For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
AERNRTDDAVVGKIVVEVVYRLSAQLAEATASIQGTLEREIVELRGDVQLLDLLHASVEGNVAAVLNAIH YDIPIERVESPTAALEYARRLAQRGVPVNALVRAYRLGHKEMLERIIDGVQEAGADPALSLDVFNRISEV TFNYIDWISQQVVAAYEAERDRWLENRSRVRNVRIAEILDGGDIDTDAMTKSIRYPLRKVHLALVLWFPD DATDGNEFERLERFLDELAEHLGTGNALFVAADRITGWGWIPLRANDAGLTGRVRRFVAGHTDAPHVALG QALPGVEGFRRAHRQARNAHRVGVAVGASAPAVMAVSDEGLSAAALMGADLPDAGAWVRETLGPLSTDSD NDAVLRETLRVFLREGGSYKAAAERLHLHYNSVKYRVARAVERRGRPIDDERLDVEMALLVCQWFGAVVP GPER*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3452 | - | - | 100% (425) | hypothetical protein MUL_3452 |
| M. ulcerans Agy99 | MUL_3434 | - | e-113 | 50.25% (408) | hypothetical protein MUL_3434 |
| M. ulcerans Agy99 | MUL_2557 | - | e-108 | 50.87% (401) | hypothetical protein MUL_2557 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1464 | - | 1e-49 | 32.56% (390) | hypothetical protein Mb1464 |
| M. gilvum PYR-GCK | Mflv_4621 | - | 8e-92 | 43.10% (413) | hypothetical protein Mflv_4621 |
| M. tuberculosis H37Rv | Rv1429 | - | 1e-49 | 32.56% (390) | hypothetical protein Rv1429 |
| M. leprae Br4923 | MLBr_01052 | - | 9e-21 | 27.08% (336) | hypothetical protein MLBr_01052 |
| M. abscessus ATCC 19977 | MAB_2657c | - | 8e-19 | 28.45% (239) | hypothetical protein MAB_2657c |
| M. marinum M | MMAR_1582 | - | 0.0 | 96.94% (425) | hypothetical protein MMAR_1582 |
| M. avium 104 | MAV_2195 | - | 1e-06 | 34.11% (129) | hypothetical protein MAV_2195 |
| M. smegmatis MC2 155 | MSMEG_6492 | - | 4e-07 | 26.86% (242) | GAF domain-containing protein |
| M. thermoresistible (build 8) | TH_2938 | - | 1e-119 | 55.82% (378) | PUTATIVE putative conserved hypothetical protein |
| M. vanbaalenii PYR-1 | Mvan_3753 | - | 4e-07 | 33.87% (124) | hypothetical protein Mvan_3753 |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_3452|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1582|M.marinum_M --------------------------------------------------
TH_2938|M.thermoresistible__bu --------------------------------------------------
Mflv_4621|M.gilvum_PYR-GCK --------------------------------------------------
Mb1464|M.bovis_AF2122/97 --------------------------------------------------
Rv1429|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01052|M.leprae_Br4923 --------------------------------------------------
MAB_2657c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_2195|M.avium_104 --------------------------------------------------
Mvan_3753|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6492|M.smegmatis_MC2_155 MTWLGALRRLSASATAEEDLSHVLAEIAETARSLLGFDFCGVLLPDEQSR
MUL_3452|M.ulcerans_Agy99 ---------------------MAERNRTDDAVVGKIVVEVVYRLSAQLAE
MMAR_1582|M.marinum_M ---------------------MAERNRTDDAAVSKIAVEVVDRLSAQLAE
TH_2938|M.thermoresistible__bu -----------------------------------------------VGY
Mflv_4621|M.gilvum_PYR-GCK ---------------------MLDSSEVQDTPG-HAVHHLFRDLGDLVRE
Mb1464|M.bovis_AF2122/97 ----------------------------MAEAGGGPISVIARHMQLIRDD
Rv1429|M.tuberculosis_H37Rv ----------------------------MAEAGGGPISVIARHMQLIRDD
MLBr_01052|M.leprae_Br4923 -----------------------MARQHPSPRVRELIREGARIALNPTQE
MAB_2657c|M.abscessus_ATCC_199 -------MNEGSERVHTQSMTPDQLWPDASEPVRRLIRELAEKMLARSGE
MAV_2195|M.avium_104 --------------------MNDNPFAGPFAKHPRSPLETLDTVPESVLR
Mvan_3753|M.vanbaalenii_PYR-1 --------------------MTDNRFIP-----PRSTVEVLENVPESTLR
MSMEG_6492|M.smegmatis_MC2_155 HLRVRGASGLSSDYVDRVNSDRPLVLHGGSPSSRAFHTAEAVAIRDVTAE
MUL_3452|M.ulcerans_Agy99 ATASIQGTLEREI--VELRGDVQLLD------------------LLHASV
MMAR_1582|M.marinum_M ATASIQGTLEREI--VELRGDAQLLD------------------LLHASV
TH_2938|M.thermoresistible__bu GPGSRQG-----------SGCRQLLE------------------LLRDSV
Mflv_4621|M.gilvum_PYR-GCK LPESIHGLLIEQV--AELAADQQLKE------------------LLSDTV
Mb1464|M.bovis_AF2122/97 FISELFDKMKAEI--RGLDYDARMAD------------------LWRASI
Rv1429|M.tuberculosis_H37Rv FISELFDKMKAEI--RGLDYDARMAD------------------LWRASI
MLBr_01052|M.leprae_Br4923 WIDQLDRATFAAN--PAIANDPVLAK------------------VVRRAS
MAB_2657c|M.abscessus_ATCC_199 VAGDLTAASLEDPRYRTIADDPVIAE------------------VDARLT
MAV_2195|M.avium_104 RLKQYSGRLATEAVSVMQDRLPFFAD------------------LEASQR
Mvan_3753|M.vanbaalenii_PYR-1 RLKQYSGRLATQAVHAMEERLPFFAE------------------LDASQR
MSMEG_6492|M.smegmatis_MC2_155 PGFELWAGIANEQGYRSMIAVPLVARGEVLGTLNGYYGAVHTYTRFEVER
. .
MUL_3452|M.ulcerans_Agy99 EGNVAAVLNAIHYDIPIERVESP-TAALEYARRLAQRG--VPVNALVRAY
MMAR_1582|M.marinum_M EGNVAAVLNAIHYDIPIERVESP-TAALEYARRLAQRG--VPVNALVRAY
TH_2938|M.thermoresistible__bu EGNIDTIFSAIQHDIPIEEVAPP-TAALEYARRLARHG--VEPHALLRAY
Mflv_4621|M.gilvum_PYR-GCK AANVDTWFSVVRHSIPFDRMESP-TAALEHARRMAQRE--VPVNALLRAY
Mb1464|M.bovis_AF2122/97 TENFVTAVHYLDRDTPQSLVEAP-AAALAYARAAAQRD--IPLSGLVRAH
Rv1429|M.tuberculosis_H37Rv TENFVTAVHYLDRDTPQSLVEAP-AAALAYARAAAQRD--IPLSGLVRAH
MLBr_01052|M.leprae_Br4923 RAHLVHWATANLRDPGAPVPAHLGPEPLTMARDLVRRG--RDVLALD-IY
MAB_2657c|M.abscessus_ATCC_199 VSNLKHWLTSNISEPGHRVRPATGSAMRTYARDVVLRG--LTTDDIQ-SW
MAV_2195|M.avium_104 ASVSLVVQTAVVNFAEWMQDPKSNVRHTAQAFELVPQD--LARRIALRHS
Mvan_3753|M.vanbaalenii_PYR-1 ASVQLVVQTAVVNFAEWMRDPRSNVSYTAQAFEVVPQD--LRRRIALRQS
MSMEG_6492|M.smegmatis_MC2_155 MTLLANHAAIAVSSARRLDELRALTASLRRQRDALTRSEQIHDRLLAVTL
:
MUL_3452|M.ulcerans_Agy99 RLGHKEMLERIIDGVQEAGADPALSLDVFNRISEVTFNYIDWISQQVVAA
MMAR_1582|M.marinum_M RLGHKEMLERIIDGVQEAGADPALSLDVFNRISEVTFNYIDWISQQVVAA
TH_2938|M.thermoresistible__bu RLGQQKLLDIVLHEIRSLDWEREVSLEFVVGVTNATFGYIDGISQRVVEV
Mflv_4621|M.gilvum_PYR-GCK RLGHQYGLNLIIAGLRSADLPPEEKLALIEHITRVSFRYIDWMSEQVLET
Mb1464|M.bovis_AF2122/97 RLGHARFLEVAMQYVS--LLEPADRVSTIIELVNRSARLVDLVADQLIVA
Rv1429|M.tuberculosis_H37Rv RLGHARFLEVAMQYVS--LLEPADRVSTIIELVNRSARLVDLVADQLIVA
MLBr_01052|M.leprae_Br4923 RVGQYTAWRRWMEIAFTLTSDPQELREILNVSAQSINEYVAATLEAIATH
MAB_2657c|M.abscessus_ATCC_199 RAVQRVGWKWWLAACFQVTDDKEQLCELIEVTSNSLTTFVDDSIAELAEH
MAV_2195|M.avium_104 VEMVRVTMEFFEEVVPLLARSEEQ----LTALTVGVLKYSRDLAFTAATA
Mvan_3753|M.vanbaalenii_PYR-1 VEMVRVTMEFFEEVVPLLARSEDQ----LAAMTAGILRYSRDLAFAAATA
MSMEG_6492|M.smegmatis_MC2_155 RSGGLDGIAAVLQGLIGRPILIDDIQHEVLACSVVTTDFPDTTWRAAAEA
.
MUL_3452|M.ulcerans_Agy99 YEAER---------------------------------------------
MMAR_1582|M.marinum_M YEAER---------------------------------------------
TH_2938|M.thermoresistible__bu YQQER---------------------------------------------
Mflv_4621|M.gilvum_PYR-GCK YQTER---------------------------------------------
Mb1464|M.bovis_AF2122/97 YEHEH---------------------------------------------
Rv1429|M.tuberculosis_H37Rv YEHEH---------------------------------------------
MLBr_01052|M.leprae_Br4923 MQLER---------------------------------------------
MAB_2657c|M.abscessus_ATCC_199 VRRVR---------------------------------------------
MAV_2195|M.avium_104 YADAA---------------------------------------------
Mvan_3753|M.vanbaalenii_PYR-1 YADQA---------------------------------------------
MSMEG_6492|M.smegmatis_MC2_155 GTGSSPVPVGQFDGTTYLASAVHLGDEVAARIWFPETSIDLDPIMVRAVE
MUL_3452|M.ulcerans_Agy99 -------------DRWLENRSRVRNVRIAEILDGGDIDTDAMTKSIRYPL
MMAR_1582|M.marinum_M -------------DRWLENRSRVRNVRIAEILDGGDIDTDAMTRSIRYPL
TH_2938|M.thermoresistible__bu -------------ERWLENRNSLRAMRVRELLDGGEVDVDTASATVGYPL
Mflv_4621|M.gilvum_PYR-GCK -------------AEWDERRRSLRAQAIRDILNGRDVDLTEASSAMRYFL
Mb1464|M.bovis_AF2122/97 -------------DRWLSRRSGLQQQWVSELLADTPVDVPRAERALGYRL
Rv1429|M.tuberculosis_H37Rv -------------DRWLSRRSGLQQQWVSELLADTPVDVPRAERALGYRL
MLBr_01052|M.leprae_Br4923 -------------DELTRSTHAERLEVVDLILEGAPVTQERAEARLGYRL
MAB_2657c|M.abscessus_ATCC_199 -------------EELAGGSQLQRYATVELLLQGADIAPARAEAQLGYAL
MAV_2195|M.avium_104 -------------EARGTWDSRMEASVVDAVVRGDTGPELLSRAAALNWD
Mvan_3753|M.vanbaalenii_PYR-1 -------------EARGAWDTRMEANLVDAVVRGGTRPELQSQAAALNWD
MSMEG_6492|M.smegmatis_MC2_155 HASIVTALELLRCQTAAEVEQRLRGELLSDVLSSGAALSDRLLDRAHRLG
. : :: .
MUL_3452|M.ulcerans_Agy99 RKVHLALVLWFPDDA-TDGNEFERLER---FLDELAEHLGT-GNALFVAA
MMAR_1582|M.marinum_M RKVHLALVLWFPDDA-TDGNEFERLER---FLDELAEHLGT-GNALFVAA
TH_2938|M.thermoresistible__bu RRTHLAVCVWTPDGS-AGDNELDRLQR---YVRGLAEALGAPGDSLFIAL
Mflv_4621|M.gilvum_PYR-GCK GATHVALMVWLDRDAGADTDEFIAMER---FMQHAVSATGA-KQSVYFSI
Mb1464|M.bovis_AF2122/97 DGVHIAAVVWVDSAVPIGDVVAQFDQVRCLLAGELGPELGPVANSLMVPT
Rv1429|M.tuberculosis_H37Rv DGVHIAAVVWVDSAVPIGDVVAQFDQVRCLLAGELGPELGPVANSLMVPT
MLBr_01052|M.leprae_Br4923 GLTHTAAVIWSDDLDGDHGYLDQAAEA--------FSHVVESTQQLIVVA
MAB_2657c|M.abscessus_ATCC_199 TGSHIGAVVWVDSEK-EIAALERASEQ--------VMRACGADRRLTVVA
MAV_2195|M.avium_104 TTAPATVVVGTPAPGRDGSTGPGDSERAS-------QHVRDIAAQHGRAA
Mvan_3753|M.vanbaalenii_PYR-1 ATAPATVIVGMPRPDR--------AEFAG-------DDVHEVADRNGRTA
MSMEG_6492|M.smegmatis_MC2_155 HDLTVPHIAIVGAFTGLDPVAERRAYERS-LVLLAKESAAHRPKPVVAMH
MUL_3452|M.ulcerans_Agy99 DRITGWGWIPLRANDA-GLTGRVRRFVAGHTDAPHVALGQALPGVEGFRR
MMAR_1582|M.marinum_M DRVTGWGWIPLRVNDA-GLAERVRRFVAGHTDAPHVALGQALPGVEGFRR
TH_2938|M.thermoresistible__bu DRLTGCGWIPLPGDAATGAVAGVRRYAAEHPDGPHLALGDPLPGLDGFRR
Mflv_4621|M.gilvum_PYR-GCK DRLVGCAWMTVHRPSD--YLSQLRDFVRAQPDGPRLSVGEPLPGIEGFRR
Mb1464|M.bovis_AF2122/97 DEREARLWFSPAPTRA-FAPSRIRAAFESAGIRARLACGRVGDGLRGFRA
Rv1429|M.tuberculosis_H37Rv DEREARLWFSPAPTRA-FAPSRIRAAFESAGIRARLACGRVGDGLRGFRA
MLBr_01052|M.leprae_Br4923 SAATRWVWLADALALD---VPEVQKALLNLS-KARVAIGTSSAGIEGFRR
MAB_2657c|M.abscessus_ATCC_199 GTVALWLWIPAKTTPT---VAVLMDSLGRRS-GVRVALGRAATGMAGFRR
MAV_2195|M.avium_104 LTDVHGTWLVAIVSGQLSPTDKFLGDLLEAFSDGPVVVGPTAPMLTAAYH
Mvan_3753|M.vanbaalenii_PYR-1 LSDVHGTWLVAIISGGLSPTDRFLSELMTVFADGPVVIGPTAPTLGAAHR
MSMEG_6492|M.smegmatis_MC2_155 AGTIVMLWPAQDAADAAGAGEVVRQAMRAASADRQATVAVGPGDVASHRE
* . . : .
MUL_3452|M.ulcerans_Agy99 AHRQARNAHRVGVAV-GASAPAVMAVSDEGLSAAALMGADLPDAGAWVRE
MMAR_1582|M.marinum_M AHRQARNAHRVGVAV-GASAPAVVAVSDEGLSAAALMGADLPEAGAWVRE
TH_2938|M.thermoresistible__bu SYRQALRTRAVAVAA-GASAPRVTAAADPGLSAAALLTGDLAEARTWVQE
Mflv_4621|M.gilvum_PYR-GCK TYRQAEQARVVAVAADGSSRHRIVAARDPGVALASMLMTDDATLKEWIHD
Mb1464|M.bovis_AF2122/97 SLKQAERVKALALAG--GARPGGRVMFYDDVAPVALLADDLEELRRFVTD
Rv1429|M.tuberculosis_H37Rv SLKQAERVKALALAG--GARPGGRVMFYDDVAPVALLADDLEELRRFVTD
MLBr_01052|M.leprae_Br4923 SHLEALTAQRTLARL----KSHQQVAFFADVQLVSLITQNPEDAKEFITS
MAB_2657c|M.abscessus_ATCC_199 THMDAAAAQRLLARL----GSPLSVVRYEDVHLMDLLSADPASADQFVTD
MAV_2195|M.avium_104 SASEAISGMNAVGGW----RGAPRPVLARELLPERALMGDASAIVALHTD
Mvan_3753|M.vanbaalenii_PYR-1 SATEAIAGMNAVAGW----AGAPRPVSARELLPERALLGDATAGAALEAE
MSMEG_6492|M.smegmatis_MC2_155 SYQTAKGALQVAIMS--GRTAAVVGLDDLGIAGLLLRINDPAALSTFARR
: * : :
MUL_3452|M.ulcerans_Agy99 TLGPLSTDSDND-AVLRETLRVFLREGGSYKAAAERLHLHYNSVKYRVAR
MMAR_1582|M.marinum_M TLGPLSTDSDND-AVLRETLRVFLREGGSYKAAAERLHLHYNSVKYRVAR
TH_2938|M.thermoresistible__bu VLGPLSADTKND-ARLRETLGVFLRHGSSYTAAADELNLHFNTVKYRVQR
Mflv_4621|M.gilvum_PYR-GCK VLGPLAQNTASD-QRLRDTLRVFLRAGSSFKAAANELQIHANTVKYRVNR
Mb1464|M.bovis_AF2122/97 VLGDLSVDDERN-SWLRETLREFLLRNRSYVATADAMILHRNTIQYRVIQ
Rv1429|M.tuberculosis_H37Rv VLGDLSVDDERN-SWLRETLREFLLRNRSYVATADAMILHRNTIQYRVIQ
MLBr_01052|M.leprae_Br4923 TLGDFESAS----PALQQTLLTFINEQCNASRAAKRLFTHRNTLLRRIES
MAB_2657c|M.abscessus_ATCC_199 VLGEFQSAS----PVLHQTVLTYVEEALNRTSTAERLYTHRNTIDRRLAR
MAV_2195|M.avium_104 VMGPLADAG----PTLIETLDAFLDSGGAIEACARKLFVHPNTVRYRLKR
Mvan_3753|M.vanbaalenii_PYR-1 VMRPLSDAG----PALMETLDAYLDSGGAIEACARKLFVHPNTVRYRLKR
MSMEG_6492|M.smegmatis_MC2_155 TLAPILDYDHAHRTELLVTLRAYLECRQERSATATRLVIHPNTVAQRLRR
.: : * *: :: * : * *:: *:
MUL_3452|M.ulcerans_Agy99 AVERRGRPIDD--ERLDVEMALLVCQWFGAVVPGPER-------------
MMAR_1582|M.marinum_M AVERRGRPIDD--ERLDVEMALLVCQWFGAVVLGPER-------------
TH_2938|M.thermoresistible__bu AVERRGRPIVP--DRLDVELALLICQWFGAAVLRPQR-------------
Mflv_4621|M.gilvum_PYR-GCK ALERRGRPIAA--ERLDVEVALLMCYWLGEVALNPTQALGRS--------
Mb1464|M.bovis_AF2122/97 AMELCGQNLDDPDAAFRVQMALEVCRWMAPAVLRAKQ-------------
Rv1429|M.tuberculosis_H37Rv AMELCGQNLDDPDAAFRVQMALEVCRWMAPAVLRAKQ-------------
MLBr_01052|M.leprae_Br4923 AEKLLPRPLDH--TSVHIAVALEALQWRGDQTNTSGPRAGRNDGVPA---
MAB_2657c|M.abscessus_ATCC_199 VDELLPKPFAR--NPIEVAAALTLLRVRAGR-------------------
MAV_2195|M.avium_104 ITDFTGRDPMQPRDAYVLRVAATVGQLNYPTHPPSAAGAAMPAVPLPVNG
Mvan_3753|M.vanbaalenii_PYR-1 IADFTGRDPTVPRDAYVLRVASSVGRLARQAH-LSAAPAAASAQAIGVAS
MSMEG_6492|M.smegmatis_MC2_155 IESLCSVTLTDPAVILQFSAALTVYDIAALD-------------------
. . *
MUL_3452|M.ulcerans_Agy99 ---------
MMAR_1582|M.marinum_M ---------
TH_2938|M.thermoresistible__bu ---------
Mflv_4621|M.gilvum_PYR-GCK ---------
Mb1464|M.bovis_AF2122/97 ---------
Rv1429|M.tuberculosis_H37Rv ---------
MLBr_01052|M.leprae_Br4923 ---------
MAB_2657c|M.abscessus_ATCC_199 ---------
MAV_2195|M.avium_104 AARGQSGG-
Mvan_3753|M.vanbaalenii_PYR-1 VTSPENLGT
MSMEG_6492|M.smegmatis_MC2_155 ---------