For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4269 | - | - | 100% (361) | virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_2834 | - | e-128 | 63.13% (358) | PUTATIVE virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_2626 | - | e-121 | 61.73% (358) | PUTATIVE virulence factor Mce family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0177 | mce1C | 2e-56 | 34.44% (360) | MCE-family protein MCE1C |
| M. gilvum PYR-GCK | Mflv_2510 | - | 1e-142 | 68.82% (356) | virulence factor Mce family protein |
| M. tuberculosis H37Rv | Rv1968 | mce3C | 2e-57 | 34.45% (357) | MCE-family protein MCE3C |
| M. leprae Br4923 | MLBr_02591 | mce1C | 2e-50 | 31.94% (360) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_4151c | - | 8e-49 | 33.03% (327) | MCE-family protein |
| M. marinum M | MMAR_4708 | - | 1e-129 | 65.00% (360) | MCE-family protein |
| M. avium 104 | MAV_0950 | - | 1e-121 | 62.57% (358) | virulence factor Mce family protein |
| M. smegmatis MC2 155 | MSMEG_2857 | - | 1e-130 | 64.25% (358) | virulence factor Mce family protein |
| M. ulcerans Agy99 | MUL_3920 | mce3C_1 | 1e-61 | 35.75% (358) | MCE-family protein, Mce3C_1 |
| M. vanbaalenii PYR-1 | Mvan_4148 | - | 1e-142 | 68.82% (356) | virulence factor Mce family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2510|M.gilvum_PYR-GCK ----MLKYRGSQLIRAGFIGVILIILVIAVGLQPERLLSWATAIRYQALF
Mvan_4148|M.vanbaalenii_PYR-1 ----MLKYRGSQLARAGFIGVVLIILVIAVGLQPERLLSWATAIRYQALF
TH_4269|M.thermoresistible__bu ----MRKYRETNLMRAGFIGFVLIVLVITIGLQPERIIQWATSIRYQALF
MMAR_4708|M.marinum_M ----MLKYRGAGLIRAGFIGAVLIVLVIAVGLNPEQLLQRATTVRYQALF
MAV_0950|M.avium_104 ----MLKYRGSGLVKAGLIGVVLAVMVILVGLSPDRFIAWATMVRYQALF
MSMEG_2857|M.smegmatis_MC2_155 ----MHKYRGTRLIRTGLLGLVLVVLIIVVGLQPQQLIQMATSVRYHAEF
Rv1968|M.tuberculosis_H37Rv ----MKSFAERNRLAIGTVGIVVVAAVALAALQYQRLPFFNQGTRVSAYF
MUL_3920|M.ulcerans_Agy99 ----MKSFAERNQIVVGAVELAITIGIVVGSLQYDKLPLFQSGKQYSACF
MAB_4151c|M.abscessus_ATCC_199 MPSKMSDIQEKDPVRTGIFGIAVVSMLVLVAFGYTGLPFWPQGKQYTGYF
Mb0177|M.bovis_AF2122/97 ----MRTLEPPNRMRIGLMGIVVALLVVAVGQSFTSVPMLFAKPSYYGQF
MLBr_02591|M.leprae_Br4923 ----MRTLELPNRLRSGLIGVLVVLLIIGVGQSFTSVPILFARPSYYGQF
* * . : : . . . *
Mflv_2510|M.gilvum_PYR-GCK TEAGGLTVGNDVTVSGIKVGSVSSIKLDNGDALVGFTIDGKYALGSDTTA
Mvan_4148|M.vanbaalenii_PYR-1 AEAGGLTVGNDVTVSGIKVGSVSSIELDNGDALVGFTIDGKYALGSDTTA
TH_4269|M.thermoresistible__bu SEAGGITVGNDVTISGIKVGTVNEVTLHDGDALVTFTVAGKHQLGAQTTA
MMAR_4708|M.marinum_M SDAGGLAVGNDVTVSGIKVGTVSGMSLQRGDVLVTFTVNGGVELGADSTA
MAV_0950|M.avium_104 TEAGGLATGNPVVVSGMKVGTVSDVKLHRGDALVTFALKGNILLGSETTA
MSMEG_2857|M.smegmatis_MC2_155 AEAGGLTAGNEVKVSGVTVGTVSDVELVNGRARVTFALDGKTRLGQDTTA
Rv1968|M.tuberculosis_H37Rv ADAGGLRTGNTVEVSGYPVGKVSSISLDGPGVLVEFKVDTDVRLGNRTEV
MUL_3920|M.ulcerans_Agy99 ADAGGLTTGVRVQVSGFRVGEVSSIELDGPQVLVKFTVDKHIRLGDHTEA
MAB_4151c|M.abscessus_ATCC_199 ADSGGLESGGNVFVSGIKVGQVKDVSLAGNKVRVDFTVDRSIRLGDQSLA
Mb0177|M.bovis_AF2122/97 TDSGGLHKGDRVRIAGLGVGTVEGLKIDGDHIVVKFSIG-TNTIGTESRL
MLBr_02591|M.leprae_Br4923 TDTGGLNKGDKVRIAGMDVGKVEALKIDGDHVVIKFSIG-TNRIGTASRL
:::**: * * ::* ** *. : : : * : :* :
Mflv_2510|M.gilvum_PYR-GCK HIRTGTLLGERVLALDSEGSGTLDPQQVIPTTRTSSPYSLTDAVSELTSN
Mvan_4148|M.vanbaalenii_PYR-1 HIRTGTLLGERVLALDSDGSGTLDPQQVIPTTRTSSPYSLTDAVSELTAN
TH_4269|M.thermoresistible__bu HIRTGSLLGERVITLESYGSEPLRGTDVIPTSRTSSPYSLTDAVGDLATN
MMAR_4708|M.marinum_M HIRTGSLLGQRVLTVESAGGHTLRPMAVIPVSRTSSPYSLSEAVSDAATD
MAV_0950|M.avium_104 HIRTGTLLGERMLTLESAGTGTMHPMALIPVSRTSSPYSLTEAVSDLTTD
MSMEG_2857|M.smegmatis_MC2_155 HIRTGTLLGQRVLTVEPKGSGRIGPSGVIPVSRTGSPYSLTDAVGDFTTN
Rv1968|M.tuberculosis_H37Rv AIKTKGLLGSKFLDVTPRGDGRLDS--PIPIERTTSPYQLPDALGDLAAT
MUL_3920|M.ulcerans_Agy99 AIKTRGLLGTKMLEVISRGDGQLQG--TIPLDRTRSPYQLPDALGDLATT
MAB_4151c|M.abscessus_ATCC_199 AIRTTTVLGEKSLSVTPAGAGRIT---EIPLGRTTTPYTLNSALSDLGAS
Mb0177|M.bovis_AF2122/97 AIRTDTILGRKVLEIEPRGAQALPPGGVLPVGQSTTPYQIYDAFFDVTKA
MLBr_02591|M.leprae_Br4923 GIRTDTVLGKKVLEVETRGTQLLRPGDSLPLGQSTTPYQSYDAFFDATKV
*:* :** : : : . * : :* :: :** .*. :
Mflv_2510|M.gilvum_PYR-GCK TRDTDTEALNQSLDTLSQTLDQIAPQLGPTFDGLSRLSQSLNSRNDSLAE
Mvan_4148|M.vanbaalenii_PYR-1 TRDTDTASLNQSLDTLAQTLDQVAPQLGPTFDGLSRLSQSLNSRNESLAE
TH_4269|M.thermoresistible__bu TAGTDTAALNQALDTLSATIDQIAPRLGPTFDGLSRLSRSLNDRNENLAG
MMAR_4708|M.marinum_M IAGTNTDALNQSLDTLSETLNQIAPQLGPSFDGLTRLSQALNGRNQTLGE
MAV_0950|M.avium_104 TAGTNTTALNQSLDTLAATLDQIAPQMGPAFDALTRLSRTLNSRNKNLGE
MSMEG_2857|M.smegmatis_MC2_155 TAETDTAAINQSLDVLSETIERIAPQLAPTFDGITRLSQSLNNRNESLAD
Rv1968|M.tuberculosis_H37Rv ISGLHTERLSESLATLAQTFADTPAHFRNAIHGVARLAQTLDERDNQLRS
MUL_3920|M.ulcerans_Agy99 ISGLNTNQLSDSLRVLADTFSDTPPQLRVAIEGVARFSQTLDERDAQLRG
MAB_4151c|M.abscessus_ATCC_199 AGGIDKAQLDQSLQVITEAMRDATPQLRGALDGVASLSRTLNARDAALEQ
Mb0177|M.bovis_AF2122/97 ASGWDIETVKRSLNVLSETVDQTYPHLSAALDGVAKFSDTIGKRDEQITH
MLBr_02591|M.leprae_Br4923 ASGWNIDTIKQSLKVVSETIDQTYPHLSAALDGVAKFSDTIGARDKEIKH
. :. :* .:: :. .:: ::..:: :: ::. *: :
Mflv_2510|M.gilvum_PYR-GCK LLRTAGEVTGIFSERSKQVNTLILNSNDLLAVLNERRYAITSLLSNISAV
Mvan_4148|M.vanbaalenii_PYR-1 LLRTAGDVTGIFSERSSQVNALILNANDLLAVLNERRYAITSLLANISAV
TH_4269|M.thermoresistible__bu LLASAGEVTKVLAERSQQLNTLILNANDLLAVLNERREAIVTLLANTSAV
MMAR_4708|M.marinum_M LLKGAADVTGILSQRSQQLNTLILNADDLLSMLVARRQAIVRLLASTSAV
MAV_0950|M.avium_104 LFKSAGDVTGVLSERSQQVNKLILNSDVLLQVLVARRQEIVDLLANTSAV
MSMEG_2857|M.smegmatis_MC2_155 LLKSASEITGILSERSEQVNRLILNANDLLAVVRDRRYVIVNLLANTSAV
Rv1968|M.tuberculosis_H37Rv LLANAAKATGVLANRTDQIVGLVRDTNVVLAQLRTQSAALDRIWANISAV
MUL_3920|M.ulcerans_Agy99 LLTNANKATTVLAERSNQVVSLIANTNALLAELTTQRAALDHISGNIAAL
MAB_4151c|M.abscessus_ATCC_199 LLTHAKSVSGILSERAGQVNKLVTDGNQLFAALDERRLAISELINRIQGL
Mb0177|M.bovis_AF2122/97 LLAQANQVASILGDRSDQVDRLLVNAKTLIAAFNERGRAVDALLGNISAF
MLBr_02591|M.leprae_Br4923 LIAQANQVASVLGDRGAQVDRLLVNTKTLIAAFNERGRAVDALLGNVAAF
*: * . : ::.:* *: *: : . :: . : : : ..
Mflv_2510|M.gilvum_PYR-GCK SQQLSGLVADNEAELAPALERLNNVTRMLEKNRDNLARMLPGAAKYYLTQ
Mvan_4148|M.vanbaalenii_PYR-1 SQQLSGVVADNEAELAPALERLNNVTQMLEKNRDNLAKMLPGAAKYYLTQ
TH_4269|M.thermoresistible__bu AQELTALVADNEAELAPTLERLNSVMEMLERNRDNIAKILPNLKKFILAQ
MMAR_4708|M.marinum_M AKQLSGLVHDNESKLAPTLERLNAVTAMLEKNRDNLAKALPGLAKYELTQ
MAV_0950|M.avium_104 AKQLTALVHDNESKLAPTLERLNSVTAMLEKNRDNISKALPGLKKFEITV
MSMEG_2857|M.smegmatis_MC2_155 ARQLSALVSDNEAELAPALEKLNKVLAMLERNRDNLTASLKGLAKYQLTQ
Rv1968|M.tuberculosis_H37Rv AEQLRGFIAENRQQLRPALDKLNGVLAIVENRKERVRQAIPLINTYVMSL
MUL_3920|M.ulcerans_Agy99 GQQLHGLIAENEATMRPALDKLNGVLTILDNRKERLQKAIKLLDDYTMSL
MAB_4151c|M.abscessus_ATCC_199 SQQISGFVADNRQEFRPTMEKLSVVLDDLLDRKAHISEALKRLPGYGTAL
Mb0177|M.bovis_AF2122/97 SAQVQNLINDN-PNLNHVLEQLRILTDLLVDRKEDLAETLTILGRFSASF
MLBr_02591|M.leprae_Br4923 AAQVQRLINDN-PNLNHVLEQLHQLSGILVQHKDDLANTLIQVAAFLPSL
. :: .: :* : .:::* : : .: : : : :
Mflv_2510|M.gilvum_PYR-GCK GEIVSNGAYYNALVPNVQPAQLLQPFLEYAFG------------------
Mvan_4148|M.vanbaalenii_PYR-1 GEIVSNGAYYNALIPNIQPAQLLQPFLDYAFG------------------
TH_4269|M.thermoresistible__bu GETLANGPYYNAFVPNLNPAQILQPFLDYAFG------------------
MMAR_4708|M.marinum_M GETVSSGFYYNPFIPNLFTIQFFQWFIDYAFG------------------
MAV_0950|M.avium_104 GEAISSMYAYSAFVPNFLAPQLFQPFLDYLWG------------------
MSMEG_2857|M.smegmatis_MC2_155 GEAVNNGFYYYGFASNLLPGPAIQPFLDYALG------------------
Rv1968|M.tuberculosis_H37Rv GESLSSGPFFKAYVVNLLPGQFVQPFISAAFSDLGLDP------------
MUL_3920|M.ulcerans_Agy99 GESVSSGPFFKTYVANLAPGQFVQPFIDAAFSDLGLDP------------
MAB_4151c|M.abscessus_ATCC_199 GEVVSSGPGFHVNVYGFPPATLTAVAFDTYF-------------------
Mb0177|M.bovis_AF2122/97 GETFASGPYFKVLLANLVPGQILQPFVDAAFKKRGISPEDFWRSAGLPAY
MLBr_02591|M.leprae_Br4923 NEAIGSGPFFKVVLHNLAPYQILQPWVDAAFKKRGIDPENFWRSAGLPEF
.* . . : .. . ..
Mflv_2510|M.gilvum_PYR-GCK ---------FRNGV-DIGQPPDNAGPRAQ---------------------
Mvan_4148|M.vanbaalenii_PYR-1 ---------FRNGV-DIGQPPDNAGPRAQ---------------------
TH_4269|M.thermoresistible__bu ---------FRRGT-NAGQPPDTVGPRAE---------------------
MMAR_4708|M.marinum_M ---------FRAHG-APGQPPDNAGPRAL---------------------
MAV_0950|M.avium_104 ---------FRTFDTARGPGHPSPVPRSL---------------------
MSMEG_2857|M.smegmatis_MC2_155 ---------FRRGV-NAGQPPDNAGPRAE---------------------
Rv1968|M.tuberculosis_H37Rv -------ATLLPSQLTDPPTGQPGTPPLP---------------------
MUL_3920|M.ulcerans_Agy99 -------NVLLPSQRTDPPIGQPGTPPLP---------------------
MAB_4151c|M.abscessus_ATCC_199 ---------------------QPGKLPAS---------------------
Mb0177|M.bovis_AF2122/97 RWPDPNGTRFPNGAPPPPPPVLEGTPEHPGPAVPPGSPCSYTPPADG---
MLBr_02591|M.leprae_Br4923 RFPDPNGTRFPNGAPPPAPPVLEGTPENPGPAVPPGSPCSYTPAHPGGNN
Mflv_2510|M.gilvum_PYR-GCK -------LPFPVNSLPQPGDLP----NDGNP-------------------
Mvan_4148|M.vanbaalenii_PYR-1 -------LPFPVNSLPQPGDLP----NDGNP-------------------
TH_4269|M.thermoresistible__bu -------LPLPYNAIPG-----------GTR-------------------
MMAR_4708|M.marinum_M -------FPFPFNQNP-----------GGSR-------------------
MAV_0950|M.avium_104 -------IPWPYNGIPVCPGCTLGGRVGGSQ-------------------
MSMEG_2857|M.smegmatis_MC2_155 -------FPFPNNGIPG-----------G---------------------
Rv1968|M.tuberculosis_H37Rv -------MPYPRTGQGGEPRLTLPDAITGNPGDPRYPYRPEPPAPPPGGP
MUL_3920|M.ulcerans_Agy99 -------LPFPRTGQGGEPHRKLPDAITGNPDDPRYPYREPLPAPPPGGP
MAB_4151c|M.abscessus_ATCC_199 -------LSDYLNGLIGE----------------RQIMRPKSP-------
Mb0177|M.bovis_AF2122/97 -------LPRPWDPLPCANLTQGPFGGPDFPAPLDVATSPPNPDGPPPAP
MLBr_02591|M.leprae_Br4923 TIGDEMGLPRPWNPLPCAGATAGPYGGPAFPAPIDVQTSPPNPDGLPLLP
:.
Mflv_2510|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4148|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4269|M.thermoresistible__bu --------------------------------------------------
MMAR_4708|M.marinum_M --------------------------------------------------
MAV_0950|M.avium_104 --------------------------------------------------
MSMEG_2857|M.smegmatis_MC2_155 --------------------------------------------------
Rv1968|M.tuberculosis_H37Rv PPGPPAQQPGDQP-------------------------------------
MUL_3920|M.ulcerans_Agy99 PPGPPAPAPPELASIPQPTPSSVLVPAPGEVSAPQTAGAGR---------
MAB_4151c|M.abscessus_ATCC_199 --------------------------------------------------
Mb0177|M.bovis_AF2122/97 GLPIAGRPGEVPPNVPGTPVPIPQEAPPGARTLPLGPAPGPAPPPAAPGP
MLBr_02591|M.leprae_Br4923 GIAIAGRPGDPAPNVPGTPVPLPPNAPPGARTEQLAPA---AP---AQDS
Mflv_2510|M.gilvum_PYR-GCK -------------------------------
Mvan_4148|M.vanbaalenii_PYR-1 -------------------------------
TH_4269|M.thermoresistible__bu -------------------------------
MMAR_4708|M.marinum_M -------------------------------
MAV_0950|M.avium_104 -------------------------------
MSMEG_2857|M.smegmatis_MC2_155 -------------------------------
Rv1968|M.tuberculosis_H37Rv -------------------------------
MUL_3920|M.ulcerans_Agy99 -------------------------------
MAB_4151c|M.abscessus_ATCC_199 -------------------------------
Mb0177|M.bovis_AF2122/97 PAPPGPGPQLPAPFINPGGTGGSGVTGGSEN
MLBr_02591|M.leprae_Br4923 SAPHEPREQLSAPLINPGGTGGSGGAGGSRN