For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2626 | - | - | 100% (364) | virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_2834 | - | e-125 | 61.98% (363) | PUTATIVE virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_4269 | - | e-121 | 61.73% (358) | PUTATIVE virulence factor Mce family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3527c | mce4C | 4e-56 | 38.73% (315) | MCE-family protein MCE4C |
| M. gilvum PYR-GCK | Mflv_2510 | - | 1e-124 | 62.36% (356) | virulence factor Mce family protein |
| M. tuberculosis H37Rv | Rv3497c | mce4C | 4e-56 | 38.73% (315) | MCE-family protein MCE4C |
| M. leprae Br4923 | MLBr_02591 | mce1C | 1e-48 | 32.38% (349) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_4151c | - | 1e-49 | 35.60% (309) | MCE-family protein |
| M. marinum M | MMAR_4708 | - | 1e-120 | 61.45% (358) | MCE-family protein |
| M. avium 104 | MAV_0950 | - | 1e-102 | 55.18% (357) | virulence factor Mce family protein |
| M. smegmatis MC2 155 | MSMEG_2857 | - | 1e-126 | 63.13% (358) | virulence factor Mce family protein |
| M. ulcerans Agy99 | MUL_3920 | mce3C_1 | 3e-59 | 38.66% (357) | MCE-family protein, Mce3C_1 |
| M. vanbaalenii PYR-1 | Mvan_4148 | - | 1e-125 | 63.48% (356) | virulence factor Mce family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3527c|M.bovis_AF2122/97 MLNRKPSSKHERDPLRTGIFGLVLVICVVLIAFGYSGLPFWPQGKTYDAY
Rv3497c|M.tuberculosis_H37Rv MLNRKPSSKHERDPLRTGIFGLVLVICVVLIAFGYSGLPFWPQGKTYDAY
MAB_4151c|M.abscessus_ATCC_199 -MPSKMSDIQEKDPVRTGIFGIAVVSMLVLVAFGYTGLPFWPQGKQYTGY
MUL_3920|M.ulcerans_Agy99 -----MKSFAERNQIVVGAVELAITIGIVVGSLQYDKLPLFQSGKQYSAC
TH_2626|M.thermoresistible__bu VRGALMLRYRGAHLVRSGFIGLVVIILIIAVGLDSEGLLTRATAVRYQAV
MSMEG_2857|M.smegmatis_MC2_155 -----MHKYRGTRLIRTGLLGLVLVVLIIVVGLQPQQLIQMATSVRYHAE
Mflv_2510|M.gilvum_PYR-GCK -----MLKYRGSQLIRAGFIGVILIILVIAVGLQPERLLSWATAIRYQAL
Mvan_4148|M.vanbaalenii_PYR-1 -----MLKYRGSQLARAGFIGVVLIILVIAVGLQPERLLSWATAIRYQAL
MMAR_4708|M.marinum_M -----MLKYRGAGLIRAGFIGAVLIVLVIAVGLNPEQLLQRATTVRYQAL
MAV_0950|M.avium_104 -----MLKYRGSGLVKAGLIGVVLAVMVILVGLSPDRFIAWATMVRYQAL
MLBr_02591|M.leprae_Br4923 -----MRTLELPNRLRSGLIGVLVVLLIIGVGQSFTSVPILFARPSYYGQ
* . : :: . . * .
Mb3527c|M.bovis_AF2122/97 FTDAGGITPGNSVYVSGLKVGAVSAVSLAGNSAKVTFSVDRSIVVGDQSL
Rv3497c|M.tuberculosis_H37Rv FTDAGGITPGNSVYVSGLKVGAVSAVSLAGNSAKVTFSVDRSIVVGDQSL
MAB_4151c|M.abscessus_ATCC_199 FADSGGLESGGNVFVSGIKVGQVKDVSLAGNKVRVDFTVDRSIRLGDQSL
MUL_3920|M.ulcerans_Agy99 FADAGGLTTGVRVQVSGFRVGEVSSIELDGPQVLVKFTVDKHIRLGDHTE
TH_2626|M.thermoresistible__bu FAEAGGLSAGADVTLSGLTVGRVSAVTLQRGKAHVVFTVDGTVGLRDATT
MSMEG_2857|M.smegmatis_MC2_155 FAEAGGLTAGNEVKVSGVTVGTVSDVELVNGRARVTFALDGKTRLGQDTT
Mflv_2510|M.gilvum_PYR-GCK FTEAGGLTVGNDVTVSGIKVGSVSSIKLDNGDALVGFTIDGKYALGSDTT
Mvan_4148|M.vanbaalenii_PYR-1 FAEAGGLTVGNDVTVSGIKVGSVSSIELDNGDALVGFTIDGKYALGSDTT
MMAR_4708|M.marinum_M FSDAGGLAVGNDVTVSGIKVGTVSGMSLQRGDVLVTFTVNGGVELGADST
MAV_0950|M.avium_104 FTEAGGLATGNPVVVSGMKVGTVSDVKLHRGDALVTFALKGNILLGSETT
MLBr_02591|M.leprae_Br4923 FTDTGGLNKGDKVRIAGMDVGKVEALKIDGDHVVIKFSIG-TNRIGTASR
*:::**: * * ::*. ** *. : : . : *:: : :
Mb3527c|M.bovis_AF2122/97 AAIRTDTILGERSIAVSPAGSGKST---TIPLSRTTTPYTLNGVLQDLGR
Rv3497c|M.tuberculosis_H37Rv AAIRTDTILGERSIAVSPAGSGKST---TIPLSRTTTPYTLNGVLQDLGR
MAB_4151c|M.abscessus_ATCC_199 AAIRTTTVLGEKSLSVTPAGAGRIT---EIPLGRTTTPYTLNSALSDLGA
MUL_3920|M.ulcerans_Agy99 AAIKTRGLLGTKMLEVISRGDGQLQG--TIPLDRTRSPYQLPDALGDLAT
TH_2626|M.thermoresistible__bu AHIRTGTLLGERVLTLRSAGTHRLRPNATIPESRTSAPYSLTDAVEELTA
MSMEG_2857|M.smegmatis_MC2_155 AHIRTGTLLGQRVLTVEPKGSGRIGPSGVIPVSRTGSPYSLTDAVGDFTT
Mflv_2510|M.gilvum_PYR-GCK AHIRTGTLLGERVLALDSEGSGTLDPQQVIPTTRTSSPYSLTDAVSELTS
Mvan_4148|M.vanbaalenii_PYR-1 AHIRTGTLLGERVLALDSDGSGTLDPQQVIPTTRTSSPYSLTDAVSELTA
MMAR_4708|M.marinum_M AHIRTGSLLGQRVLTVESAGGHTLRPMAVIPVSRTSSPYSLSEAVSDAAT
MAV_0950|M.avium_104 AHIRTGTLLGERMLTLESAGTGTMHPMALIPVSRTSSPYSLTEAVSDLTT
MLBr_02591|M.leprae_Br4923 LGIRTDTVLGKKVLEVETRGTQLLRPGDSLPLGQSTTPYQSYDAFFDATK
*:* :** : : : . * :* :: :** .. :
Mb3527c|M.bovis_AF2122/97 NANDLNRPQFEQALNVFTQALHDATPQVRGAVDGLTSLSRALNRRDEALQ
Rv3497c|M.tuberculosis_H37Rv NANDLNRPQFEQALNVFTQALHDATPQVRGAVDGLTSLSRALNRRDEALQ
MAB_4151c|M.abscessus_ATCC_199 SAGGIDKAQLDQSLQVITEAMRDATPQLRGALDGVASLSRTLNARDAALE
MUL_3920|M.ulcerans_Agy99 TISGLNTNQLSDSLRVLADTFSDTPPQLRVAIEGVARFSQTLDERDAQLR
TH_2626|M.thermoresistible__bu NVAATDTDTLTRSLDVLSDTIEQIAPQVGPTFEGLTRISRLLNERDSRVR
MSMEG_2857|M.smegmatis_MC2_155 NTAETDTAAINQSLDVLSETIERIAPQLAPTFDGITRLSQSLNNRNESLA
Mflv_2510|M.gilvum_PYR-GCK NTRDTDTEALNQSLDTLSQTLDQIAPQLGPTFDGLSRLSQSLNSRNDSLA
Mvan_4148|M.vanbaalenii_PYR-1 NTRDTDTASLNQSLDTLAQTLDQVAPQLGPTFDGLSRLSQSLNSRNESLA
MMAR_4708|M.marinum_M DIAGTNTDALNQSLDTLSETLNQIAPQLGPSFDGLTRLSQALNGRNQTLG
MAV_0950|M.avium_104 DTAGTNTTALNQSLDTLAATLDQIAPQMGPAFDALTRLSRTLNSRNKNLG
MLBr_02591|M.leprae_Br4923 VASGWNIDTIKQSLKVVSETIDQTYPHLSAALDGVAKFSDTIGARDKEIK
: : :* ..: :: *:: :.:.:: :* :. *: :
Mb3527c|M.bovis_AF2122/97 GLLAHAKSVTSVLSERAEQVNKLVEDGNQLFAALDARRAALSALISGIDD
Rv3497c|M.tuberculosis_H37Rv GLLAHAKSVTSVLSERAEQVNKLVEDGNQLFAALDARRAALSALISGIDD
MAB_4151c|M.abscessus_ATCC_199 QLLTHAKSVSGILSERAGQVNKLVTDGNQLFAALDERRLAISELINRIQG
MUL_3920|M.ulcerans_Agy99 GLLTNANKATTVLAERSNQVVSLIANTNALLAELTTQRAALDHISGNIAA
TH_2626|M.thermoresistible__bu DLLTEAAAVTDVLASRAEQVNALILNANDLIAVLNDRRQHIVRLLGYASA
MSMEG_2857|M.smegmatis_MC2_155 DLLKSASEITGILSERSEQVNRLILNANDLLAVVRDRRYVIVNLLANTSA
Mflv_2510|M.gilvum_PYR-GCK ELLRTAGEVTGIFSERSKQVNTLILNSNDLLAVLNERRYAITSLLSNISA
Mvan_4148|M.vanbaalenii_PYR-1 ELLRTAGDVTGIFSERSSQVNALILNANDLLAVLNERRYAITSLLANISA
MMAR_4708|M.marinum_M ELLKGAADVTGILSQRSQQLNTLILNADDLLSMLVARRQAIVRLLASTSA
MAV_0950|M.avium_104 ELFKSAGDVTGVLSERSQQVNKLILNSDVLLQVLVARRQEIVDLLANTSA
MLBr_02591|M.leprae_Br4923 HLIAQANQVASVLGDRGAQVDRLLVNTKTLIAAFNERGRAVDALLGNVAA
*: * : ::..*. *: *: : . *: . : : :
Mb3527c|M.bovis_AF2122/97 VAAQISGFVADNRKEFGPALSKLNLVLANLNERRDYITEALKRLPTYATT
Rv3497c|M.tuberculosis_H37Rv VAAQISGFVADNRKEFGPALSKLNLVLANLNERRDYITEALKRLPTYATT
MAB_4151c|M.abscessus_ATCC_199 LSQQISGFVADNRQEFRPTMEKLSVVLDDLLDRKAHISEALKRLPGYGTA
MUL_3920|M.ulcerans_Agy99 LGQQLHGLIAENEATMRPALDKLNGVLTILDNRKERLQKAIKLLDDYTMS
TH_2626|M.thermoresistible__bu VARDLQGLVAENEAELAPALERLNSVTAMLERNRDSIEAALPGLAKFQTT
MSMEG_2857|M.smegmatis_MC2_155 VARQLSALVSDNEAELAPALEKLNKVLAMLERNRDNLTASLKGLAKYQLT
Mflv_2510|M.gilvum_PYR-GCK VSQQLSGLVADNEAELAPALERLNNVTRMLEKNRDNLARMLPGAAKYYLT
Mvan_4148|M.vanbaalenii_PYR-1 VSQQLSGVVADNEAELAPALERLNNVTQMLEKNRDNLAKMLPGAAKYYLT
MMAR_4708|M.marinum_M VAKQLSGLVHDNESKLAPTLERLNAVTAMLEKNRDNLAKALPGLAKYELT
MAV_0950|M.avium_104 VAKQLTALVHDNESKLAPTLERLNSVTAMLEKNRDNISKALPGLKKFEIT
MLBr_02591|M.leprae_Br4923 FAAQVQRLINDN-PNLNHVLEQLHQLSGILVQHKDDLANTLIQVAAFLPS
.. :: .: :* : .:.:* : * .: : : : :
Mb3527c|M.bovis_AF2122/97 LGEVVGSGPGFNVNVYSVLPGPLVATVFDLVF------------------
Rv3497c|M.tuberculosis_H37Rv LGEVVGSGPGFNVNVYSVLPGPLVATVFDLVF------------------
MAB_4151c|M.abscessus_ATCC_199 LGEVVSSGPGFHVNVYGFPPATLTAVAFDTYF------------------
MUL_3920|M.ulcerans_Agy99 LGESVSSGPFFKTYVANLAPGQFVQPFIDAAFSDLGLDPNVLLPSQRTDP
TH_2626|M.thermoresistible__bu QGETVSNGFYYTANIPNLLPGQLLQPFLDYALG-----------------
MSMEG_2857|M.smegmatis_MC2_155 QGEAVNNGFYYYGFASNLLPGPAIQPFLDYALG-----------------
Mflv_2510|M.gilvum_PYR-GCK QGEIVSNGAYYNALVPNVQPAQLLQPFLEYAFG-----------------
Mvan_4148|M.vanbaalenii_PYR-1 QGEIVSNGAYYNALIPNIQPAQLLQPFLDYAFG-----------------
MMAR_4708|M.marinum_M QGETVSSGFYYNPFIPNLFTIQFFQWFIDYAFG-----------------
MAV_0950|M.avium_104 VGEAISSMYAYSAFVPNFLAPQLFQPFLDYLWG-----------------
MLBr_02591|M.leprae_Br4923 LNEAIGSGPFFKVVLHNLAPYQILQPWVDAAFKKRGIDPENFWRSAGLPE
.* :.. : .. . .:
Mb3527c|M.bovis_AF2122/97 ---QPGK---------------------------LPDS---------LAD
Rv3497c|M.tuberculosis_H37Rv ---QPGK---------------------------LPDS---------LAD
MAB_4151c|M.abscessus_ATCC_199 ---QPGK---------------------------LPAS---------LSD
MUL_3920|M.ulcerans_Agy99 PIGQPGTPPLPLP---------------------FPRTGQGGEPHRKLPD
TH_2626|M.thermoresistible__bu --FRRGV-------------------------------------NAGQPP
MSMEG_2857|M.smegmatis_MC2_155 --FRRGV-------------------------------------NAGQPP
Mflv_2510|M.gilvum_PYR-GCK --FRNGV-------------------------------------DIGQPP
Mvan_4148|M.vanbaalenii_PYR-1 --FRNGV-------------------------------------DIGQPP
MMAR_4708|M.marinum_M --FRAHG-------------------------------------APGQPP
MAV_0950|M.avium_104 --FRTFDT------------------------------------ARGPGH
MLBr_02591|M.leprae_Br4923 FRFPDPNGTRFPNGAPPPAPPVLEGTPENPGPAVPPGSPCSYTPAHPGGN
Mb3527c|M.bovis_AF2122/97 YLRGFIQE-RWIIRPKSP--------------------------------
Rv3497c|M.tuberculosis_H37Rv YLRGFIQE-RWIIRPKSP--------------------------------
MAB_4151c|M.abscessus_ATCC_199 YLNGLIGE-RQIMRPKSP--------------------------------
MUL_3920|M.ulcerans_Agy99 AITGNPDDPRYPYREPLPAPPPGGPPPGPPAPAPPELASIPQPTPSSVLV
TH_2626|M.thermoresistible__bu DNAGPRAELPFPRNGIP-----------GG--------------------
MSMEG_2857|M.smegmatis_MC2_155 DNAGPRAEFPFPNNGIP-----------GG--------------------
Mflv_2510|M.gilvum_PYR-GCK DNAGPRAQLPFPVNSLPQPGDLP----NDGNP------------------
Mvan_4148|M.vanbaalenii_PYR-1 DNAGPRAQLPFPVNSLPQPGDLP----NDGNP------------------
MMAR_4708|M.marinum_M DNAGPRALFPFPFNQNP-----------GGSR------------------
MAV_0950|M.avium_104 PSPVPRSLIPWPYNGIPVCPGCTLGGRVGGSQ------------------
MLBr_02591|M.leprae_Br4923 NTIGDEMGLPRPWNPLPCAGATAGPYGGPAFPAPIDVQTSPPNPDGLPLL
.
Mb3527c|M.bovis_AF2122/97 --------------------------------------------------
Rv3497c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_4151c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_3920|M.ulcerans_Agy99 PAPGEVSAPQTAGAGR----------------------------------
TH_2626|M.thermoresistible__bu --------------------------------------------------
MSMEG_2857|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2510|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4148|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_4708|M.marinum_M --------------------------------------------------
MAV_0950|M.avium_104 --------------------------------------------------
MLBr_02591|M.leprae_Br4923 PGIAIAGRPGDPAPNVPGTPVPLPPNAPPGARTEQLAPAAPAQDSSAPHE
Mb3527c|M.bovis_AF2122/97 --------------------------
Rv3497c|M.tuberculosis_H37Rv --------------------------
MAB_4151c|M.abscessus_ATCC_199 --------------------------
MUL_3920|M.ulcerans_Agy99 --------------------------
TH_2626|M.thermoresistible__bu --------------------------
MSMEG_2857|M.smegmatis_MC2_155 --------------------------
Mflv_2510|M.gilvum_PYR-GCK --------------------------
Mvan_4148|M.vanbaalenii_PYR-1 --------------------------
MMAR_4708|M.marinum_M --------------------------
MAV_0950|M.avium_104 --------------------------
MLBr_02591|M.leprae_Br4923 PREQLSAPLINPGGTGGSGGAGGSRN