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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3971 | - | - | 100% (550) | putative putative acyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_3577 | - | 2e-92 | 39.69% (509) | PUTATIVE putative putative acyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_4072 | - | 5e-76 | 36.20% (558) | PUTATIVE AMP-dependent synthetase and ligase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2533c | fadD35 | 1e-54 | 29.63% (540) | AMP-binding domain protein |
| M. gilvum PYR-GCK | Mflv_4363 | - | 2e-91 | 39.05% (525) | AMP-dependent synthetase and ligase |
| M. tuberculosis H37Rv | Rv2505c | fadD35 | 1e-54 | 29.63% (540) | AMP-binding domain protein |
| M. leprae Br4923 | MLBr_02661 | - | 9e-32 | 25.14% (533) | acyl-CoA synthetase |
| M. abscessus ATCC 19977 | MAB_4377c | - | 2e-52 | 30.48% (525) | AMP-binding domain protein |
| M. marinum M | MMAR_4026 | fadD35_1 | 5e-91 | 38.05% (502) | fatty-acid-CoA ligase FadD35_1 |
| M. avium 104 | MAV_1579 | - | 2e-95 | 41.05% (497) | putative acyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_2216 | - | 2e-88 | 37.57% (527) | AMP-binding enzyme |
| M. ulcerans Agy99 | MUL_4126 | fadD3 | 1e-38 | 27.98% (504) | acyl-CoA synthetase |
| M. vanbaalenii PYR-1 | Mvan_1981 | - | 4e-85 | 38.08% (499) | AMP-dependent synthetase and ligase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2533c|M.bovis_AF2122/97 MAAAEVVDPNRLSYDRGPSAPSLLE-----------------STIGANLA
Rv2505c|M.tuberculosis_H37Rv MAAAEVVDPNRLSYDRGPSAPSLLE-----------------STIGANLA
MAB_4377c|M.abscessus_ATCC_199 ----------MKAYDAGATLSPIIE-----------------ETIGENFE
MUL_4126|M.ulcerans_Agy99 --------------------MTSDP-----------------RTVPTALD
Mflv_4363|M.gilvum_PYR-GCK ------------------------MSDP--------------CTVAEVLR
Mvan_1981|M.vanbaalenii_PYR-1 -----------------------MTPDP--------------ATVADVLR
MMAR_4026|M.marinum_M -----------------------MAADS--------------PTVAQILR
MAV_1579|M.avium_104 -----------------------MPGDF--------------ATVGATLR
MSMEG_2216|M.smegmatis_MC2_155 -----------------------MAETL--------------VELLEGLR
TH_3971|M.thermoresistible__bu -----------------------MTSTPSATRVFRYEPLPYDAVLPAMLA
MLBr_02661|M.leprae_Br4923 MKSESITSSRAPVEQIDARLTGQFES----------------PSIASLVE
: .
Mb2533c|M.bovis_AF2122/97 ATAARYGHREALVDMVA---RRRFNYSELLTDVHRLATGLVRAGIGPGDR
Rv2505c|M.tuberculosis_H37Rv ATAARYGHREALVDMVA---RRRFNYSELLTDVHRLATGLVRAGIGPGDR
MAB_4377c|M.abscessus_ATCC_199 RIARAHPDVGALVDVSG---DRRWTYRELDAEINRVARGLMSLGVAAGDR
MUL_4126|M.ulcerans_Agy99 RLVRRLPNHDALVTD-----ERSFTVSELNDEVYRAAAALIELGVKPAAR
Mflv_4363|M.gilvum_PYR-GCK AQRRHG-DKPLLICDD-----ERLSYAEADERSAVLAARLTTLGVGKGSH
Mvan_1981|M.vanbaalenii_PYR-1 RQRLWA-DKPLLVCDR-----TRLSYGEADERSAVLAQRLVALGAGKGTH
MMAR_4026|M.marinum_M RQARCRPDHPFLVCDS-----DRISYAQADLRSAELARGLIALGIGKAAH
MAV_1579|M.avium_104 HQARWRGDHPLLICDA-----ERISYAEADVRSAELARGLIALGAGKGTH
MSMEG_2216|M.smegmatis_MC2_155 D----RGDHTLLVCDD-----ERLTYADAEHRSARLADALIALGAGKGTH
TH_3971|M.thermoresistible__bu AVTGAHSAGDLVVTVTGDGSVERITYGEAEDRSADMAARLLAAGVTKGVR
MLBr_02661|M.leprae_Br4923 AAAIRNPSAPALVVTDN---RIVVSYRDLLRLVDDLTVQLALGGLLPGDR
:: . : : * * . :
Mb2533c|M.bovis_AF2122/97 VGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVI
Rv2505c|M.tuberculosis_H37Rv VGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVI
MAB_4377c|M.abscessus_ATCC_199 VGIWAPNCAEWVLVQYATAKIGAILVNINPAYRTHELAYALNQSGVRTLI
MUL_4126|M.ulcerans_Agy99 VGIWSPNTWHWVVACLAIHHVGAAMVPLNTRYTADEAADILARTEAPVLF
Mflv_4363|M.gilvum_PYR-GCK VGILYPNGAQWVVAMLAAARIGAVVVPFSTFSTAVELRRQLRDSDVGVLL
Mvan_1981|M.vanbaalenii_PYR-1 VGLLYPNSAEFVVAMLAATRIGAVVVPFSTFGTAPEVRRQLVDSDVSVLL
MMAR_4026|M.marinum_M VGLLYPNGSDFVIGMLAAARIGAVVIPISTFVTPRELHEQLVDSDTQILL
MAV_1579|M.avium_104 VGLLHPNGARFVVAMLAAARIGAVVVPFSTFVTVRELREQLLDSDVEILL
MSMEG_2216|M.smegmatis_MC2_155 VGVLYPNGADFVVAMLAVARVGAVVVPFSTFLTEAELRVQLLDSDVSIML
TH_3971|M.thermoresistible__bu VGILAPNGPDFVTAFLATARIGAVAVPINTFFQPPELEWVLRDADIHTLL
MLBr_02661|M.leprae_Br4923 VALCAASNIEFVVGLLAASRAGLIVVPLDPALPVNEQCIRSQAAGVRVTL
*.: .. :* * . * : :.. * : :
Mb2533c|M.bovis_AF2122/97 AVASFKDADYAAMLAEVG-------------PRCPDLADVILLESDRWDA
Rv2505c|M.tuberculosis_H37Rv AVASFKDADYAAMLAEVG-------------PRCPDLADVILLESDRWDA
MAB_4377c|M.abscessus_ATCC_199 CAKAFKSSDYVAMASQVM-------------PDAPGLRDVVFIGTSDWTE
MUL_4126|M.ulcerans_Agy99 AMGHFLGSDRVAGLDRKA-------------LPALRHIVRIPIEEPDGTW
Mflv_4363|M.gilvum_PYR-GCK ATRAFRTHDYVRALGEAVGVPLDDG--PLLSAEVPVLRHVVFD---AECG
Mvan_1981|M.vanbaalenii_PYR-1 AARSFRSHDYVQTLTDAVGARPTHG--PVFSTAAPVLRHVLFDDQDSDAR
MMAR_4026|M.marinum_M SADTFRSHDYAGRLRQLLGDTGFDGEDRLFSRAIPQLR-TAWVSYRRGAP
MAV_1579|M.avium_104 SARSFRPHDYARRLSEAVSETDFDPGRRLFCTAAPQLRRVLFAPQTVGAP
MSMEG_2216|M.smegmatis_MC2_155 SARSFRSHDYVGQISRVR-------------ADAPCLRHVVFEIPAAGDP
TH_3971|M.thermoresistible__bu AVETLLGRDMFERIEAAAGEWQVVDG-QLRIERLPQLRNILPLGTARREW
MLBr_02661|M.leprae_Br4923 VDSLALEGVSDQRAATMR-------------YWPIAVSYGSVTGASEGSL
Mb2533c|M.bovis_AF2122/97 LAG----------AEPDLPALQQTAARLDGS--DPVNIQYTSGTTAYPKG
Rv2505c|M.tuberculosis_H37Rv LAG----------AEPDLPALQQTAARLDGS--DPVNIQYTSGTTAYPKG
MAB_4377c|M.abscessus_ATCC_199 LVAG--------AERVTETALRARMSQLSNT--DPINIQYTSGTTGYPKG
MUL_4126|M.ulcerans_Agy99 DEFI--------ETGTDTGAVTARAAAVSPD--DVSDILFTSGTTGRSKG
Mflv_4363|M.gilvum_PYR-GCK G-------------AAD---VSALEGDVDGS--DVLAIIYTSGSTSDPKG
Mvan_1981|M.vanbaalenii_PYR-1 G-------------RVDDALLRAMEDDVDGC--DPLAVIYTSGSTSAPKG
MMAR_4026|M.marinum_M RRTRSIECVYRLSQTIDPTMLRALEDDVDGS--DVLAIVYTSGTTSAPKG
MAV_1579|M.avium_104 ------------GGGIDPALLAAMEDDVQAC--DPLAIVYTSGSTSTPKG
MSMEG_2216|M.smegmatis_MC2_155 E------------------RRAGLEADVEGS--DVLAIIYTSGSTGAPKG
TH_3971|M.thermoresistible__bu P--------SSWPDPVPENFRKACEATVRSA--DDLLVIYTSGSTSTPKG
MLBr_02661|M.leprae_Br4923 LVH-----------LDDTAALHPVTSTPDGLRHDDAMIMFTGGTTGLPKM
* : :*.*:*. .*
Mb2533c|M.bovis_AF2122/97 VTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMGNLAATSHG
Rv2505c|M.tuberculosis_H37Rv VTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMGNLAATSHG
MAB_4377c|M.abscessus_ATCC_199 ATLSHRNVLNNGFFVAESIQLQAGDRLCIPVPFYHCFGMVMGNLGCTTHG
MUL_4126|M.ulcerans_Agy99 VLCAHRQSLSASASWAANGKITADDRHLCINPFFHNFGYKAGILACLQTG
Mflv_4363|M.gilvum_PYR-GCK VVHTHTSLLAHQRGLNEIRGLTAEDRLFCNSPFFWIGGFAFGLLATLVAG
Mvan_1981|M.vanbaalenii_PYR-1 VVHTHAALLAHQRSLNEIRRLTADDRLFCNSPFFWIGGFAFGLLATLVAG
MMAR_4026|M.marinum_M VVHTHSALVRHQQNLNVIRGLGTDDKLFCNSPFCWIGGFAFGLLATLLAG
MAV_1579|M.avium_104 VVHTHGALLEHQRNLNGIRGLTADDRLFCNSPFFWIGGFAFGLLATLVAG
MSMEG_2216|M.smegmatis_MC2_155 VVHTHSSLLAHQRDLNVLRGLTADDKLFCNSPFFWVGGLAFALLASMIAG
TH_3971|M.thermoresistible__bu IIHTHGTTITHSRFIATAHDWDHNDRIYVPMVFFWVAGLVFGFLGPMQVG
MLBr_02661|M.leprae_Br4923 VPWTDGNIAGSVHAIITAYQLGPQDATVVVMPLYHGHGLIAALLSTLASG
:. * : * . *. *
Mb2533c|M.bovis_AF2122/97 AAMVIPAPG-FDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELG
Rv2505c|M.tuberculosis_H37Rv AAMVIPAPG-FDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELG
MAB_4377c|M.abscessus_ATCC_199 ATIVMPAPG-FDPGRTLEAIERERCVGVYGVPTMFIAMLADPGFAHRDLS
MUL_4126|M.ulcerans_Agy99 ATLFPHLT--FDPLRTLQAIERHRITVLPGPPTIYQTLLDHPARDDYDLS
Mflv_4363|M.gilvum_PYR-GCK -STLICSTA-SDAGRTLDLLEAEKPTMTNGFVAGITHLTRHPSFARRDLS
Mvan_1981|M.vanbaalenii_PYR-1 -ATLICSNA-TDAADTLDLLEAEKPTVTNGFVAGITHLPRHPSFARRDLS
MMAR_4026|M.marinum_M -STLVCSNA--DAATTLDLLEREKPTMTNGFASTVARLANHPSFGRRDLS
MAV_1579|M.avium_104 -STLICSNA-TDAGATLDLLEAEKPTMTNGFSAGIAHLAEHPSFADRDLS
MSMEG_2216|M.smegmatis_MC2_155 -ATLVCSNS-TDAGATFDLLEAEKPTITNGFVAGIAHLTRHPSFPHRNLS
TH_3971|M.thermoresistible__bu -AAILTEHK-FDAGEVLRLLQSEKATYTTGFGHIGPALVNHPDFASTDLS
MLBr_02661|M.leprae_Br4923 GVVLLPARARFSARTFWDDIDAVAATWYTAAPAIHRILLELASTQSFRSK
. .. :: . . .
Mb2533c|M.bovis_AF2122/97 SLRTGIMAGAACPVEVMRKVISRMHMPG-VSICYGMTETSPVSTQT----
Rv2505c|M.tuberculosis_H37Rv SLRTGIMAGAACPVEVMRKVISRMHMPG-VSICYGMTETSPVSTQT----
MAB_4377c|M.abscessus_ATCC_199 TLRTGIMAGSVCPVEVMKRCIDEMHMAG-VAIAYGMTETSPVSCQT----
MUL_4126|M.ulcerans_Agy99 SLRFAVTGAATVPVVLVERMQSELDIDI-VLTAYGLTEANGMGTMC----
Mflv_4363|M.gilvum_PYR-GCK SMRRGNLYSIMAPDVRPADPELRHNMLG-MTEAGSVVLLSGD--------
Mvan_1981|M.vanbaalenii_PYR-1 SMRRGNLYPIMAAGARPADAELRHNMLG-MTETGSVVLLSGD--------
MMAR_4026|M.marinum_M SMRRGNLYPIMAPEARPVDPELRHNMLG-MTEAGSIVLISAD--------
MAV_1579|M.avium_104 SMRRGNLYPIMAVEARPADPELRHNMLG-MTEAGGVVLIGDD--------
MSMEG_2216|M.smegmatis_MC2_155 SIRRGNLYPLMAPDVRPADPDLRHNMLG-STESGSVVLLDPD--------
TH_3971|M.thermoresistible__bu SLREGYQQVLLPPERRTPDPSLRVAQLG-MTETCSSHTWWPP--------
MLBr_02661|M.leprae_Br4923 RAKLRFIRSCSAPLTQETAQALREEFLAPVICAFGMTEATHQVTTTNIKW
: . .
Mb2533c|M.bovis_AF2122/97 -RADDSVDRRVGTVGRVGPHLEIKVVDPATGETVPRGVVGEFCTRGYSVM
Rv2505c|M.tuberculosis_H37Rv -RADDSVDRRVGTVGRVGPHLEIKVVDPATGETVPRGVVGEFCTRGYSVM
MAB_4377c|M.abscessus_ATCC_199 -LFDDDLDRRTATVGRAHPHIEIKIVDPNSGETVQRGQSGELCTRGYSVM
MUL_4126|M.ulcerans_Agy99 -RADDDALTVATTCGRPFADFELRIG-PDTGEVLLRGP---------NVM
Mflv_4363|M.gilvum_PYR-GCK --ESDQPEARRGSYGFLAPGFDARVVDPDTGSDTDG-AVGELVLRGPHLM
Mvan_1981|M.vanbaalenii_PYR-1 --DSDQPESRRGSFGFLAPGFQARVVDPDTGCDVAVSTPGVLLLRGPFLM
MMAR_4026|M.marinum_M --ESDQPESRRGSFGKPAPGFDTIIIEPGTGEVANVGQVGELCIRGPFVM
MAV_1579|M.avium_104 --EADQPEHRRGSFGKPAPGFEARILDPDTGAAVAVGEVGELCIRGPYLM
MSMEG_2216|M.smegmatis_MC2_155 --DTDQPEHRRGSFGRPAPGFETKVLD-----------SGELCIRGPYLM
TH_3971|M.thermoresistible__bu --HEELPEAKRGSLGVSAPGYEHKIVD-EAGNEVPNGVTGEICVRGTAMM
MLBr_02661|M.leprae_Br4923 FGQGENPTVTNGLVG-QSTGVQIRIVGSD-GQPLPPDTVGEVWLRGSTVV
: * . : : ::
Mb2533c|M.bovis_AF2122/97 AGYWNDPQKTAEVIDADGWMHTGDLAEMDPSGYVRIAGRIKDLVVRGGEN
Rv2505c|M.tuberculosis_H37Rv AGYWNDPQKTAEVIDADGWMHTGDLAEMDPSGYVRIAGRIKDLVVRGGEN
MAB_4377c|M.abscessus_ATCC_199 LGYWNDEAHTREVLDTDGWMHTGDLAVMRDDGYCTIIGRLKDMVIRGGEN
MUL_4126|M.ulcerans_Agy99 LGYLDDPRATAAAIDADGWLHTGDIGVLDEAGNLRITDRLKDMYICGGFN
Mflv_4363|M.gilvum_PYR-GCK QRYYG--RSREECFDADGWFHTGDLVRRDDDGVFYFVGRAGSMIKTAGAN
Mvan_1981|M.vanbaalenii_PYR-1 QGYYG--RAREDCFDGDGWFDTGDLVRRDGDGVFYFIGRTGTMIKTAGAN
MMAR_4026|M.marinum_M QGYYK--RSREECFDADGWFHTGDLVRADQDGYMYFTGRLSSLIKTAGAN
MAV_1579|M.avium_104 QRYHK--RSREECFDPDGWFHTGDLVRADADGYFYFAGRLGAMIKTAGAN
MSMEG_2216|M.smegmatis_MC2_155 QGYYG--RSREECFDTDGWFHTGDLVRVDDDGYFYFLGRAGAMIKTAGAN
TH_3971|M.thermoresistible__bu RAMVG--RHWFELVDRDGWLHTKDAGYRDDDGHLYFAGRLDEMIKTSGTN
MLBr_02661|M.leprae_Br4923 RGYLGDPAITAANFT-HGWLRTGDLGSLSVTGDLRIRGRIKELINRSGEK
. .**: * * * : .* : .* :
Mb2533c|M.bovis_AF2122/97 ISPREIEELLHTHPD-----IVDGHVIGVPDAKYGEELMAVVKLRNDAPE
Rv2505c|M.tuberculosis_H37Rv ISPREIEELLHTHPD-----IVDGHVIGVPDAKYGEELMAVVKLRNDAPE
MAB_4377c|M.abscessus_ATCC_199 IYPREIEEFLLTHPD-----IEDVHVVGVPDEKYGEELCAWVRMRPDRVV
MUL_4126|M.ulcerans_Agy99 VYPAEVEQVLARLDG-----VADVAVIGIPDHRLGEVGRAFIVARPG-FN
Mflv_4363|M.gilvum_PYR-GCK VAPAEVEKALSAALQAV-DAGVAVHVVGLPDPERGQIVAAVIATDNG-TV
Mvan_1981|M.vanbaalenii_PYR-1 VAPGEVEKAIIAVIP---DPDVVVHVVGLPDAERGQLVAAVIASD---TE
MMAR_4026|M.marinum_M VSPAEVERAIAKLG-------MVAHVVGIPDPQRGQVVAAVLVVADGVGA
MAV_1579|M.avium_104 VSAVEVEKAIAAVTG-----GATAYVVGIPDARRGQLVAAAVVWPDDRAA
MSMEG_2216|M.smegmatis_MC2_155 VTPDEVQKALQHVLEGRDMRDVTVQVVGLPDQERGQLVAAVVATADP-AA
TH_3971|M.thermoresistible__bu VAPMEVEAALGKIEAVR-----IAYVVGVPDPEKGAIVSAAVVLNEG-YT
MLBr_02661|M.leprae_Br4923 ISPERVEGVLASHHN-----VMEVAVFGDPDKVYGETVTAVIVPREVIAP
: . .:: : *.* ** * * :
Mb2533c|M.bovis_AF2122/97 LTIERLREYCMGRIARFKIPR---YLWIVDEFPMTVTGKVRKVEMRQQAL
Rv2505c|M.tuberculosis_H37Rv LTIERLREYCMGRIARFKIPR---YLWIVDEFPMTVTGKVRKVEMRQQAL
MAB_4377c|M.abscessus_ATCC_199 IDAVAIRAFASGRLAHYKIPR---YVHVVESFPMTVTGKVRKIEMRQQTI
MUL_4126|M.ulcerans_Agy99 LDEKSVIDYTREHLANFKAPR---SVRFVDTLPRNAGGKVVKPQLRELA-
Mflv_4363|M.gilvum_PYR-GCK FDEPAVKEALSTQVSAYKIPRRVLSLRHTE-IPTMSSGKIDLAALRRLFD
Mvan_1981|M.vanbaalenii_PYR-1 VDVSGLQETLRSHLSAYKIPRRVATVRHAD-IPMLSSGKVDLSALRRLFG
MMAR_4026|M.marinum_M LDELALRERLETELSAYKIPTRFATLPPSE-IPLLSSGKVDTHQLKKCFD
MAV_1579|M.avium_104 LDPDALRERLKSELSAYKIPRRFASLRRAD-VPLLSSGKVDLRQLRKLFD
MSMEG_2216|M.smegmatis_MC2_155 FDEAAVRAALRAQLSSYKVPRRFAVIHSDE-LPVKSSGKIDVAALRELFD
TH_3971|M.thermoresistible__bu ATADDLVAECRSRLAAYKVPKKWAILSDADRLPYTTTNKIDKVRLTQLMA
MLBr_02661|M.leprae_Br4923 TP-SELAVFCRDRLAAFEVPTR---FQEASALPHTAKGSLDRRAVAEQFA
: .:: :: * . . .* ..: : .
Mb2533c|M.bovis_AF2122/97 EYLRGQQ-------
Rv2505c|M.tuberculosis_H37Rv EYLRGQQ-------
MAB_4377c|M.abscessus_ATCC_199 QIFGLPEPGRTDEQ
MUL_4126|M.ulcerans_Agy99 --------------
Mflv_4363|M.gilvum_PYR-GCK D-------------
Mvan_1981|M.vanbaalenii_PYR-1 ALR-----------
MMAR_4026|M.marinum_M A-------------
MAV_1579|M.avium_104 A-------------
MSMEG_2216|M.smegmatis_MC2_155 D-------------
TH_3971|M.thermoresistible__bu SGELC---------
MLBr_02661|M.leprae_Br4923 HRG-----------