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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4072 | - | - | 100% (548) | AMP-dependent synthetase and ligase |
| M. thermoresistible (build 8) | TH_3577 | - | 5e-87 | 38.81% (554) | PUTATIVE putative putative acyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_3971 | - | 5e-76 | 36.20% (558) | PUTATIVE putative putative acyl-CoA dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2533c | fadD35 | 1e-43 | 28.75% (560) | AMP-binding domain protein |
| M. gilvum PYR-GCK | Mflv_3245 | - | 0.0 | 67.50% (523) | AMP-dependent synthetase and ligase |
| M. tuberculosis H37Rv | Rv2505c | fadD35 | 1e-43 | 28.75% (560) | AMP-binding domain protein |
| M. leprae Br4923 | MLBr_02546 | fadD2 | 8e-23 | 24.67% (531) | acyl-CoA synthetase |
| M. abscessus ATCC 19977 | MAB_4377c | - | 1e-37 | 26.83% (533) | AMP-binding domain protein |
| M. marinum M | MMAR_4026 | fadD35_1 | 3e-78 | 36.51% (545) | fatty-acid-CoA ligase FadD35_1 |
| M. avium 104 | MAV_1579 | - | 6e-76 | 37.00% (546) | putative acyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_3468 | - | 0.0 | 69.33% (525) | AMP-binding enzyme |
| M. ulcerans Agy99 | MUL_4126 | fadD3 | 1e-38 | 29.72% (545) | acyl-CoA synthetase |
| M. vanbaalenii PYR-1 | Mvan_2960 | - | 0.0 | 67.98% (531) | AMP-dependent synthetase and ligase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2533c|M.bovis_AF2122/97 ------MAAAEVVDPNRLSYDRGPSAPSLLESTIGANLAATAARYGHREA
Rv2505c|M.tuberculosis_H37Rv ------MAAAEVVDPNRLSYDRGPSAPSLLESTIGANLAATAARYGHREA
MAB_4377c|M.abscessus_ATCC_199 ----------------MKAYDAGATLSPIIEETIGENFERIARAHPDVGA
MUL_4126|M.ulcerans_Agy99 --------------------------MTSDPRTVPTALDRLVRRLPNHDA
Mflv_3245|M.gilvum_PYR-GCK --------------------------MDHTPLTVPALLTDAVRRFGERTY
Mvan_2960|M.vanbaalenii_PYR-1 --------------------------MDS--LTIPALLSAAVRARGERIY
MSMEG_3468|M.smegmatis_MC2_155 --------------------------MTPAPLTVPALLQRSVREFGDDTY
TH_4072|M.thermoresistible__bu ---------------------VAGPVNRVTALTVPALLAGAAETFGDRTY
MMAR_4026|M.marinum_M --------------------------MAADSPTVAQILRRQARCRPDHPF
MAV_1579|M.avium_104 --------------------------MPGDFATVGATLRHQARWRGDHPL
MLBr_02546|M.leprae_Br4923 MTKLRHYLERGAAEVHYLRSIFESGALGFEPPLTYAAMAVAMRKWGDLAM
: .
Mb2533c|M.bovis_AF2122/97 LVDMVA------------RRRFNYSELLTDVHRLATGLVRAGIGPGDRVG
Rv2505c|M.tuberculosis_H37Rv LVDMVA------------RRRFNYSELLTDVHRLATGLVRAGIGPGDRVG
MAB_4377c|M.abscessus_ATCC_199 LVDVSG------------DRRWTYRELDAEINRVARGLMSLGVAAGDRVG
MUL_4126|M.ulcerans_Agy99 LVTD--------------ERSFTVSELNDEVYRAAAALIELGVKPAARVG
Mflv_3245|M.gilvum_PYR-GCK VVTPGGT----------PDTRLTYADAEAQSADKARWLLANGAGKGTRVG
Mvan_2960|M.vanbaalenii_PYR-1 LVTP--------------TERLTYAAAERRSAELARWLLGQGVGKGTRVG
MSMEG_3468|M.smegmatis_MC2_155 LVTP--------------TGRATYREIDNLSVRAARWLLGQGAGKGTRVG
TH_4072|M.thermoresistible__bu VVTP--------------AERLSYRQAADRSARLARWLLREGVGKGTRVG
MMAR_4026|M.marinum_M LVCD--------------SDRISYAQADLRSAELARGLIALGIGKAAHVG
MAV_1579|M.avium_104 LICD--------------AERISYAEADVRSAELARGLIALGAGKGTHVG
MLBr_02546|M.leprae_Br4923 LPAMPARRSPHRAALIDEEGTLTYKELDRAAHALANGLIAKGVRGGDGIA
: . * *: * . :.
Mb2533c|M.bovis_AF2122/97 IWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIAV
Rv2505c|M.tuberculosis_H37Rv IWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIAV
MAB_4377c|M.abscessus_ATCC_199 IWAPNCAEWVLVQYATAKIGAILVNINPAYRTHELAYALNQSGVRTLICA
MUL_4126|M.ulcerans_Agy99 IWSPNTWHWVVACLAIHHVGAAMVPLNTRYTADEAADILARTEAPVLFAM
Mflv_3245|M.gilvum_PYR-GCK LFFANDTEWVTWWLAVSRIGALAVPLSTLYRPAEIAKVLRLADIALLVAP
Mvan_2960|M.vanbaalenii_PYR-1 LFFPNGAEWVTWWLAVSRVGAVAVPLSTMYRPAEIAKVIRLADVALLIGP
MSMEG_3468|M.smegmatis_MC2_155 LFFANGIEWITWWLAVSRIGAVAVPLSTLYTPAEIAKVLRLADVGILVAP
TH_4072|M.thermoresistible__bu LFFPNGTDWIVWWLAVSRIGALAVPLSTLYQPAEIAKVVRLADIAVLIAP
MMAR_4026|M.marinum_M LLYPNGSDFVIGMLAAARIGAVVIPISTFVTPRELHEQLVDSDTQILLSA
MAV_1579|M.avium_104 LLHPNGARFVVAMLAAARIGAVVVPFSTFVTVRELREQLLDSDVEILLSA
MLBr_02546|M.leprae_Br4923 ILARNHRWFVIANYGCARVGARIILLNSEFSGPQIKEVSEREGAKVIIYD
: * :: . .:** : :.. : :.
Mb2533c|M.bovis_AF2122/97 ASFKDADYAAMLAEVG-------------PRCPDLADVILLESDRWDALA
Rv2505c|M.tuberculosis_H37Rv ASFKDADYAAMLAEVG-------------PRCPDLADVILLESDRWDALA
MAB_4377c|M.abscessus_ATCC_199 KAFKSSDYVAMASQVM-------------PDAPGLRDVVFIGTSDWTELV
MUL_4126|M.ulcerans_Agy99 GHFLGSDRVAGLDRKA-------------LPALRHIVRIPIEEPDGTWDE
Mflv_3245|M.gilvum_PYR-GCK NRVLDIDVAQRLEAALPGLEGHRTPHLQIAAAPYLR-SIAITGHSDAPWA
Mvan_2960|M.vanbaalenii_PYR-1 TRILDIDVVSRFEEALPELSGHDGPRLALTEAPFLR-RIALTGPVAAPWA
MSMEG_3468|M.smegmatis_MC2_155 PRVLNIDVGLRLREALPELAGQPSRAIAVRATPFLR-RIAITGETDLPCA
TH_4072|M.thermoresistible__bu GTVLSIDVPARFEQAWPELAGQRAGQLALTAAPYLR-TIVLTEPTDRPWA
MMAR_4026|M.marinum_M DTFRSHDYAGRLRQLLGDTGFDGEDRLFSRAIPQLR-TAWVSYRRGAPRR
MAV_1579|M.avium_104 RSFRPHDYARRLSEAVSETDFDPGRRLFCTAAPQLRRVLFAPQTVGAP--
MLBr_02546|M.leprae_Br4923 DEYT--KVVSKAEPALG----------------KLRALGVNPDEEEPPGS
.
Mb2533c|M.bovis_AF2122/97 G----------AEPDLPALQQTAARLDGSDPVNIQYTSGTTAYPKGVTLS
Rv2505c|M.tuberculosis_H37Rv G----------AEPDLPALQQTAARLDGSDPVNIQYTSGTTAYPKGVTLS
MAB_4377c|M.abscessus_ATCC_199 AG--------AERVTETALRARMSQLSNTDPINIQYTSGTTGYPKGATLS
MUL_4126|M.ulcerans_Agy99 FI--------ETGTDTGAVTARAAAVSPDDVSDILFTSGTTGRSKGVLCA
Mflv_3245|M.gilvum_PYR-GCK TAVD-----GAQTVSPDILLAAQEQVFPGDLAIMVHTSGSTADPKGVLHT
Mvan_2960|M.vanbaalenii_PYR-1 TTID-----DADSVPSRVQAAAEAEVSPADLAIMVHTSGSTADPKGVMHT
MSMEG_3468|M.smegmatis_MC2_155 TRID-----DTG-VPQEILAAAESEVSPADLAVMVHTSGSTADPKGVLHT
TH_4072|M.thermoresistible__bu ARWKP----DAATAAPELLSAVEAEVSPADLAVMVHTSGSTADPKGVLHT
MMAR_4026|M.marinum_M TRSIECVYRLSQTIDPTMLRALEDDVDGSDVLAIVYTSGTTSAPKGVVHT
MAV_1579|M.avium_104 ----------GGGIDPALLAAMEDDVQACDPLAIVYTSGSTSTPKGVVHT
MLBr_02546|M.leprae_Br4923 TDET------LAELIARSSSAPAPKVR-KRASIIILTSGTTGTPKGANRN
: : ***:*. .**.
Mb2533c|M.bovis_AF2122/97 HRNILNNGYLVGELLGYTA-------------------QDRICIPVPFYH
Rv2505c|M.tuberculosis_H37Rv HRNILNNGYLVGELLGYTA-------------------QDRICIPVPFYH
MAB_4377c|M.abscessus_ATCC_199 HRNVLNNGFFVAESIQLQA-------------------GDRLCIPVPFYH
MUL_4126|M.ulcerans_Agy99 HRQSLSASASWAANGKITA-------------------DDRHLCINPFFH
Mflv_3245|M.gilvum_PYR-GCK HGTLVRQTSTWPAAIRAVT---------------GSPADPVILSAMPFFW
Mvan_2960|M.vanbaalenii_PYR-1 HGTVVRQTSTWPAAVRAIT---------------GSDADPVILCAMPFFW
MSMEG_3468|M.smegmatis_MC2_155 HGTLVRQTSTWPAAIRAVT---------------GSQGHARILCAMPFFW
TH_4072|M.thermoresistible__bu HGTLVRQTSTWPAAIWAVTRGSGTGSHTGAESGAGTADEPRILCAMPFFW
MMAR_4026|M.marinum_M HSALVRHQQNLN-VIRGLG------------------TDDKLFCNSPFCW
MAV_1579|M.avium_104 HGALLEHQRNLN-GIRGLT------------------ADDRLFCNSPFFW
MLBr_02546|M.leprae_Br4923 TPASLAPLGGILSKVPFRA-------------------HEVTLLPAPMFH
: *:
Mb2533c|M.bovis_AF2122/97 CFGMVMGNLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFI
Rv2505c|M.tuberculosis_H37Rv CFGMVMGNLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFI
MAB_4377c|M.abscessus_ATCC_199 CFGMVMGNLGCTTHGATIVMPAPGFDPGRTLEAIERERCVGVYGVPTMFI
MUL_4126|M.ulcerans_Agy99 NFGYKAGILACLQTGATLFPHLT-FDPLRTLQAIERHRITVLPGPPTIYQ
Mflv_3245|M.gilvum_PYR-GCK IGG-LLAAMGALHES-ITLLVMPRLDAATALDLVEAERATGIVGWPAFTQ
Mvan_2960|M.vanbaalenii_PYR-1 IGG-VLAATGALHEP-VTLLVMPKLDAETALDLAENEKATGIVGWPAFTQ
MSMEG_3468|M.smegmatis_MC2_155 IGG-LLAATGALHEP-VTLAILPKLDAGAALDLAERERITGIVGWPAFTQ
TH_4072|M.thermoresistible__bu IGG-LLAATGALHDP-VTLLVLPKLDAGTALDLIETERATGVVGWPAFTR
MMAR_4026|M.marinum_M IGGFAFGLLATLLAG-STLVCSNA-DAATTLDLLEREKPTMTNGFASTVA
MAV_1579|M.avium_104 IGGFAFGLLATLVAG-STLICSNATDAGATLDLLEAEKPTMTNGFSAGIA
MLBr_02546|M.leprae_Br4923 ALGYLHATLAMFLGS--TLVLRRRFKPATVLEDIEKHQATAMVVVPVMLS
* . . . .. .* : .: . .
Mb2533c|M.bovis_AF2122/97 AELGLPD--FTDYELGSLRTGIMAGAACPVEVMRKVISRMHMPGVSICYG
Rv2505c|M.tuberculosis_H37Rv AELGLPD--FTDYELGSLRTGIMAGAACPVEVMRKVISRMHMPGVSICYG
MAB_4377c|M.abscessus_ATCC_199 AMLADPG--FAHRDLSTLRTGIMAGSVCPVEVMKRCIDEMHMAGVAIAYG
MUL_4126|M.ulcerans_Agy99 TLLDHPA--RDDYDLSSLRFAVTGAATVPVVLVERMQSELDIDIVLTAYG
Mflv_3245|M.gilvum_PYR-GCK RMREHPS--FPRRDLSSV-----------------PMLRSGPLDIAMT--
Mvan_2960|M.vanbaalenii_PYR-1 RMREHPS--FADRDLSSA-----------------PMLRDGPLDIAMT--
MSMEG_3468|M.smegmatis_MC2_155 RLREHPT--FSVRDLSSA-----------------PMLRDGPLDIAMT--
TH_4072|M.thermoresistible__bu RLRDHPT--FDERDLGSA-----------------PMLRHGPLDIAMT--
MMAR_4026|M.marinum_M RLANHPS--FGRRDLSSMRRGNLYPIMAPEARPVDPELRHNMLGMTEAG-
MAV_1579|M.avium_104 HLAEHPS--FADRDLSSMRRGNLYPIMAVEARPADPELRHNMLGMTEAG-
MLBr_02546|M.leprae_Br4923 RILDTLENLETKSDLSSLRVVFVSGSQLGAELATRALEELGPVIYNMYG-
:*.: .
Mb2533c|M.bovis_AF2122/97 MTETSPVSTQTRADDSVDRRVGTVGRVGPHLEIKVVDPATGETVPRGVVG
Rv2505c|M.tuberculosis_H37Rv MTETSPVSTQTRADDSVDRRVGTVGRVGPHLEIKVVDPATGETVPRGVVG
MAB_4377c|M.abscessus_ATCC_199 MTETSPVSCQTLFDDDLDRRTATVGRAHPHIEIKIVDPNSGETVQRGQSG
MUL_4126|M.ulcerans_Agy99 LTEANGMGTMCRADDDALTVATTCGRPFADFELRIG-PDTGEVLLRGP--
Mflv_3245|M.gilvum_PYR-GCK ----------DVPDGFPVHRTMTETAGGFAYTEMKIVDADGAPVDDGTVG
Mvan_2960|M.vanbaalenii_PYR-1 ----------DVPDGFPVHRTMSETAGGFAHTEMKIVDDAGMPVAAGVVG
MSMEG_3468|M.smegmatis_MC2_155 ----------DVPDGFPVHRTMTETAGGFAYTDMRIVDDNGVPAPDGTVG
TH_4072|M.thermoresistible__bu ----------DVPDGFPVHRTMSETAGGFAFTEMRIVDGNGDPVPDGTVG
MMAR_4026|M.marinum_M ----SIVLISADESDQPESRRGSFGKPAPGFDTIIIEPGTGEVANVGQVG
MAV_1579|M.avium_104 ----GVVLIGDDEADQPEHRRGSFGKPAPGFEARILDPDTGAAVAVGEVG
MLBr_02546|M.leprae_Br4923 ---STEIAFATIAGPKDLQINSATVGPVVKGVKVKILDDSGKEVPRGQVG
: * *
Mb2533c|M.bovis_AF2122/97 EFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMDP-SGYVRIAGR
Rv2505c|M.tuberculosis_H37Rv EFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMDP-SGYVRIAGR
MAB_4377c|M.abscessus_ATCC_199 ELCTRGYSVMLGYWNDEAHTREVLDTDGWMHTGDLAVMRD-DGYCTIIGR
MUL_4126|M.ulcerans_Agy99 -------NVMLGYLDDPRATAAAIDADGWLHTGDIGVLDE-AGNLRITDR
Mflv_3245|M.gilvum_PYR-GCK ELWVRGVGVMAGYNK--RERSDTFDADGWYHTGDRVYRSAGDPRLFYVGR
Mvan_2960|M.vanbaalenii_PYR-1 ELLVRGVGVMAGYNK--RERSDTFDADGWYHTGDRVYRRADDPRLFFVGR
MSMEG_3468|M.smegmatis_MC2_155 ELHVRGIGVMAGYNK--RERFETFDDDGWYHTGDKVYRRPGDPRVFYVGR
TH_4072|M.thermoresistible__bu ELLVRGIGVMAGYNK--RERWEVFDADGWYHTGDRVYRKPGDPRLFYVGR
MMAR_4026|M.marinum_M ELCIRGPFVMQGYYK--RSREECFDADGWFHTGD-LVRADQDGYMYFTGR
MAV_1579|M.avium_104 ELCIRGPYLMQRYHK--RSREECFDPDGWFHTGD-LVRADADGYFYFAGR
MLBr_02546|M.leprae_Br4923 RIFVGNAFPFEGYTG----GGGKQIIDGLLSSGDVGYFDE-HDLLYISGR
: * ** :** .*
Mb2533c|M.bovis_AF2122/97 IKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKL
Rv2505c|M.tuberculosis_H37Rv IKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKL
MAB_4377c|M.abscessus_ATCC_199 LKDMVIRGGENIYPREIEEFLLTHPDIEDVHVVGVPDEKYGEELCAWVRM
MUL_4126|M.ulcerans_Agy99 LKDMYICGGFNVYPAEVEQVLARLDGVADVAVIGIPDHRLGEVGRAFIVA
Mflv_3245|M.gilvum_PYR-GCK TTELIKTSGANVSPLEVEAVIESFDEVAQCVVVGIDHVERGEEVCAVLVP
Mvan_2960|M.vanbaalenii_PYR-1 TGEMIKTSGANVSPLEVEAVIETFDDIAQCVVVGVEHADRGEEVCAVLVP
MSMEG_3468|M.smegmatis_MC2_155 TTDLIKAAGANVSPLEVEAVLAGFGEVAQCLVLGVDDAERGEEVCAVVVP
TH_4072|M.thermoresistible__bu TTELIKSGGANVSPLEVEAVIEQSPAVAQCVVVGVDDPDRGEQVCAVVVP
MMAR_4026|M.marinum_M LSSLIKTAGANVSPAEVERAIAKLG--MVAHVVGIPDPQRGQVVAAVLVV
MAV_1579|M.avium_104 LGAMIKTAGANVSAVEVEKAIAAVTGGATAYVVGIPDARRGQLVAAAVVW
MLBr_02546|M.leprae_Br4923 DDEMIVSGGENVFPAEVEDLISGHPEVVEATAIGVDDKEWGARLRAFVVK
: .* *: . *:* : .:*: . * * :
Mb2533c|M.bovis_AF2122/97 R-NDAPELTIERLREYCMGRIARFKIPR--YLWIVDEFPMTVTGKVRKVE
Rv2505c|M.tuberculosis_H37Rv R-NDAPELTIERLREYCMGRIARFKIPR--YLWIVDEFPMTVTGKVRKVE
MAB_4377c|M.abscessus_ATCC_199 R-PDRVVIDAVAIRAFASGRLAHYKIPR--YVHVVESFPMTVTGKVRKIE
MUL_4126|M.ulcerans_Agy99 R-PG-FNLDEKSVIDYTREHLANFKAPR--SVRFVDTLPRNAGGKVVKPQ
Mflv_3245|M.gilvum_PYR-GCK S---GDTVDTATLAERTRELLSPFKVPTRWITVDSARIPTLPSGKLNRKA
Mvan_2960|M.vanbaalenii_PYR-1 V---GNEVDVDSVARRTREALSSYKVPTRWVIASSEQIPTLPSGKLDRRA
MSMEG_3468|M.smegmatis_MC2_155 SGTPGDTLDVALLAQRAREQLSAYKVPTRWVIACSDDIPTLPSGKFDRKA
TH_4072|M.thermoresistible__bu THSGDHGLDVDSLAAQVGSQLSSYKVPTRWVVARADQIPTLPSGKFDRRT
MMAR_4026|M.marinum_M A-DGVGALDELALRERLETELSAYKIPTRFATLPPSEIPLLSSGKVDTHQ
MAV_1579|M.avium_104 P-DDRAALDPDALRERLKSELSAYKIPRRFASLRRADVPLLSSGKVDLRQ
MLBr_02546|M.leprae_Br4923 K--QDATIDEDAIKAYVRDHLARYKVPR--EVIFLEELPRNPTGKVLKRE
: : :: :* * .* **.
Mb2533c|M.bovis_AF2122/97 MRQQALEYLRGQQ---------
Rv2505c|M.tuberculosis_H37Rv MRQQALEYLRGQQ---------
MAB_4377c|M.abscessus_ATCC_199 MRQQTIQIFGLPEPGRTDEQ--
MUL_4126|M.ulcerans_Agy99 LRELA-----------------
Mflv_3245|M.gilvum_PYR-GCK LREWVISSPAAGVR--------
Mvan_2960|M.vanbaalenii_PYR-1 VRALIVSSGAAKAD--------
MSMEG_3468|M.smegmatis_MC2_155 LRRWIIDERLGVTAR-------
TH_4072|M.thermoresistible__bu LRARVSDGTLNAVQPVNADSRR
MMAR_4026|M.marinum_M LKKCFDA---------------
MAV_1579|M.avium_104 LRKLFDA---------------
MLBr_02546|M.leprae_Br4923 LRDFEVH---------------
::