For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3969 | - | - | 100% (280) | short-chain dehydrogenase/reductase SDR |
| M. thermoresistible (build 8) | TH_2589 | - | 6e-39 | 38.93% (244) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. thermoresistible (build 8) | TH_3708 | - | 1e-33 | 34.96% (246) | PUTATIVE short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2025 | fabG3 | 1e-30 | 36.03% (247) | 20-beta-hydroxysteroid dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1963 | - | 3e-72 | 49.28% (276) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2002 | fabG3 | 1e-30 | 36.03% (247) | 20-beta-hydroxysteroid dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 1e-18 | 29.96% (257) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0833 | - | 4e-38 | 36.89% (244) | Short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_0587 | - | 5e-33 | 37.10% (248) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_1242 | - | 2e-31 | 33.61% (244) | short-chain dehydrogenase/reductase SDR |
| M. smegmatis MC2 155 | MSMEG_1782 | - | 7e-69 | 47.58% (269) | oxidoreductase, short chain dehydrogenase/reductase family |
| M. ulcerans Agy99 | MUL_0676 | - | 4e-28 | 32.06% (262) | carveol-like dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_4753 | - | 3e-75 | 51.45% (276) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1963|M.gilvum_PYR-GCK ----------MTDDVTPDA-VIPYPGETQDMSDRPRDDMRDYVGRGLLDG
Mvan_4753|M.vanbaalenii_PYR-1 ----------MSDDVTPEG-VIPYPGQTADMTPQPRDEMRDYTGTGLLSG
MSMEG_1782|M.smegmatis_MC2_155 MDSFESDKPGADQDLNDQHNVISYPGHTEDMADKPRDEMAQYVGRGLLEG
TH_3969|M.thermoresistible__bu ----------MGFPEQQQQ----VPGRQSAMDPVPDCGESSYRGSGKLTG
MMAR_0587|M.marinum_M --------------------------------------------MGQLEG
MAV_1242|M.avium_104 --------------------------------------------MGKLDG
MAB_0833|M.abscessus_ATCC_1997 ------------------------------------MNRETFSRLFDLTG
Mb2025|M.bovis_AF2122/97 -------------------------------------------MSGRLIG
Rv2002|M.tuberculosis_H37Rv -------------------------------------------MSGRLIG
MUL_0676|M.ulcerans_Agy99 --------------------------------------------MGALDG
MLBr_01807|M.leprae_Br4923 -----------------------------MTDAAAKVSAAPGRGKPAFVS
: .
Mflv_1963|M.gilvum_PYR-GCK KKALITGGDSGIGRAVAVAFAKEGADVAIAYLNETS-----------DAA
Mvan_4753|M.vanbaalenii_PYR-1 KRALITGGDSGIGRAVAIAFAKEGADVAIAYLEEQA-----------DAA
MSMEG_1782|M.smegmatis_MC2_155 KRALISGGDSGIGRAVAVAFAKEGADVAIAYLDEHD-----------DAT
TH_3969|M.thermoresistible__bu KRAVITGGDSGIGRAVAIAYAREGADVLVSYLNEDD-----------DAA
MMAR_0587|M.marinum_M KTALVTGGNSGIGLAAAQRLAAEGAHVFLTGRNQA------------TID
MAV_1242|M.avium_104 KVAVITGGSSGLALATAKLFVDEGAHVFITGRRRH------------ALD
MAB_0833|M.abscessus_ATCC_1997 RTAIVTGGTRGIGRALAEGYACAGANVVVASRKPE------------ACT
Mb2025|M.bovis_AF2122/97 KVALVSGGARGMGASHVRAMVAEGAKVVFGDILD-----------EEGKA
Rv2002|M.tuberculosis_H37Rv KVALVSGGARGMGASHVRAMVAEGAKVVFGDILD-----------EEGKA
MUL_0676|M.ulcerans_Agy99 RVALITGGARGQGRAHALALAGKGADIALADAPGPMAELTYPLGSEEDLL
MLBr_01807|M.leprae_Br4923 RSILVTGGNRGIGLAVARRLVADGHRVAVTHRAS----------------
: :::** * . : . . * : .
Mflv_1963|M.gilvum_PYR-GCK HTVSLIEAQGRPGLELPGDLAEPGHCRSIVEQTVKEFGGLDIVVNNVAFQ
Mvan_4753|M.vanbaalenii_PYR-1 HTVSLIEAAGQRGIQLPGDLADPSHCRGVVAETVKQLGGLDIVVNNVAFQ
MSMEG_1782|M.smegmatis_MC2_155 HTASLVERTGRRCLRLPGDLSEVEQCRAIVSRTAGALGGIDIVVNNVAYQ
TH_3969|M.thermoresistible__bu EVAQLVTDAGRRCVLVPGDLSDPAHCRSVIDRAVSEFDGLDVLVVNHAHQ
MMAR_0587|M.marinum_M AAVA---SIGSRAHGIRADVSNIEDLARVADAIAAAGRGLDVLFANAG-G
MAV_1242|M.avium_104 EAVA---SIGRNVTAVQGDAANLDDLDRLFDTVKREKGSIDILFASAGTG
MAB_0833|M.abscessus_ATCC_1997 EAVERLRSLGARALGVPTHTGDIHSLEELVRATAEEFGGIDIVVNNAA-N
Mb2025|M.bovis_AF2122/97 VAAELADAAR----YVHLDVTQPAQWTAAVDTAVTAFGGLHVLVNNAG-I
Rv2002|M.tuberculosis_H37Rv VAAELADAAR----YVHLDVTQPAQWTAAVDTAVTAFGGLHVLVNNAG-I
MUL_0676|M.ulcerans_Agy99 ATAELVGQLGRRCLPMVVDVRDPAQVNTAVERTVRELGSLDIVLANAG-I
MLBr_01807|M.leprae_Br4923 -------VVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPVEVLVANAG-I
: . : :.::. . .
Mflv_1963|M.gilvum_PYR-GCK SPADDLTEISDEQWRRTFAVNIDSFFHVTKAALSHLPDG--SAIINTASI
Mvan_4753|M.vanbaalenii_PYR-1 SPVSDLAEISDEQWRRTFAVNIDSFFHVTKAALQHLPDG--SAIINTGSI
MSMEG_1782|M.smegmatis_MC2_155 RPTEKFTDISDEQWRHTFAVNIDSFFYVTKAALEYLPDG--GAIINTASI
TH_3969|M.thermoresistible__bu MTHPTLEEISDEEWDYTFRLNIGAYFHLVKAALPHLKPG--ASIIGSSSV
MMAR_0587|M.marinum_M GEFVLLGDITIEHFTNGFMTNVAGTLFTVQTMLPLLNSG--ASIVLTGST
MAV_1242|M.avium_104 GQARRLGEITEQDFDTVFGLNTRATLFTVQKALPLFNDG--GSILMTGSI
MAB_0833|M.abscessus_ATCC_1997 ALTEPVGAFTVDGWDKSFGVNLRGPVFLVQAALPHLVASPHAAVLNVVSV
Mb2025|M.bovis_AF2122/97 LNIGTIEDYALTEWQRILDVNLTGVFLGIRAVVKPMKEAGRGSIINISSI
Rv2002|M.tuberculosis_H37Rv LNIGTIEDYALTEWQRILDVNLTGVFLGIRAVVKPMKEAGRGSIINISSI
MUL_0676|M.ulcerans_Agy99 VSTGRLEEVSDQVWQQLMDTNLTGVFHTLRAAIPVMRQQRFGRIVATSSM
MLBr_01807|M.leprae_Br4923 TSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFGRYIFMGSV
. : : : * . . : : . : *
Mflv_1963|M.gilvum_PYR-GCK NGLRGNKSLIDYSATKGAVIALTYSLAQSLAQRRIRVNCVAPGPVWTPLI
Mvan_4753|M.vanbaalenii_PYR-1 NGLRGNKTLIDYSATKGAVIALTYSLAQSLADRNIRVNCVAPGPVWTPLI
MSMEG_1782|M.smegmatis_MC2_155 NGLRGNKTLIDYSATKGAVIALTYALAQSLTERRIRVNCVAPGPVWTPLI
TH_3969|M.thermoresistible__bu NSDMPSPTLAPYAATKAAIANFSASLAQMLGDKGIRVNSVAPGPIWTPLI
MMAR_0587|M.marinum_M AAYNGSPAFSVYAATKAAIRSFGRTWAAELVSRNIRVNTVVPGPVETPGL
MAV_1242|M.avium_104 ASVKGWPDYSVYSASKAALRSFARTWLNELKDRRIRVNVLSPGQVATP-I
MAB_0833|M.abscessus_ATCC_1997 GAFMFGQGVSMYSAAKAALVSYTRSAAAELASRGVRVNALAPGAIDTD-M
Mb2025|M.bovis_AF2122/97 EGLAGTVACHGYTATKFAVRGLTKSTALELGPSGIRVNSIHPGLVKTPMT
Rv2002|M.tuberculosis_H37Rv EGLAGTVACHGYTATKFAVRGLTKSTALELGPSGIRVNSIHPGLVKTPMT
MUL_0676|M.ulcerans_Agy99 GGRMGIPELAAYNATKWGIIGLIKSVALEVAKEGITANVICPTTTQTPMM
MLBr_01807|M.leprae_Br4923 VGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVVAPGFIDTEMT
. * *:* .: : : : .* : * *
Mflv_1963|M.gilvum_PYR-GCK PATMDADKVESFGG--------QVPMGRAAQPDEIAPSYVFFAASQMSSY
Mvan_4753|M.vanbaalenii_PYR-1 PATMDAEKTASFGE--------HVPMGRAAQPDEIAPSYVFFAASRMSSY
MSMEG_1782|M.smegmatis_MC2_155 PATMDAERVESFGE--------QAPYNRAAQPDEIAPSYVFFAADQLSSY
TH_3969|M.thermoresistible__bu PSTMPPEKVARFGD--------DTPLGRAGQPAELAGAYVLLAADEGS-Y
MMAR_0587|M.marinum_M KGLAPEGQEQQLLEGEA----AKVPMGRLGKPAEIAAAVLFLASDQSS-F
MAV_1242|M.avium_104 QEKMFDAETKRQFE-------SLIPRGTMGRPEEIATAALFLASDDSS-Y
MAB_0833|M.abscessus_ATCC_1997 VRKTPPAEVERMAN--------TNHLKRLGLPDEMVGTALLLTSDAGS-Y
Mb2025|M.bovis_AF2122/97 DWVPEDIFQTALGRAAEPVEVSNLVVYLASDESSYSTGAEFVVDGGTVAG
Rv2002|M.tuberculosis_H37Rv DWVPEDIFQTALGRAAEPVEVSNLVVYLASDESSYSTGAEFVVDGGTVAG
MUL_0676|M.ulcerans_Agy99 QPAGIGDDQEVPDDLVRRMMKANPIPQPWLQPEDVSRGVVYLVTDPGVIT
MLBr_01807|M.leprae_Br4923 RAMDSKYQEAALQA---------IPLGRIGAVEEIAGAVSFLASEDAG-Y
. ..
Mflv_1963|M.gilvum_PYR-GCK YSGEVLAPIGGETLPG---
Mvan_4753|M.vanbaalenii_PYR-1 YSGEVLAPIGGETLPV---
MSMEG_1782|M.smegmatis_MC2_155 YTGEVLAPIGGETLPG---
TH_3969|M.thermoresistible__bu ISGARIAVTGGRPIL----
MMAR_0587|M.marinum_M MTGSEMFVDGGTEQL----
MAV_1242|M.avium_104 VNGVELAVDGGTSAI----
MAB_0833|M.abscessus_ATCC_1997 ITGQTIIADGGLVAR----
Mb2025|M.bovis_AF2122/97 LAHNDFGAVEVSSQPEWVT
Rv2002|M.tuberculosis_H37Rv LAHNDFGAVEVSSQPEWVT
MUL_0676|M.ulcerans_Agy99 GSVLEVGLGGSARMH----
MLBr_01807|M.leprae_Br4923 ISGAVIPVDGGLGMGH---
.