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M. thermoresistible (build 8) TH_3708 (-)

annotation: short-chain dehydrogenase/reductase SDR
coordinates: 3979834 - 3980598
length: 255

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3708--100% (255)short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_3170-1e-7960.00% (240) PUTATIVE short-chain type dehydrogenase/reductase
M. thermoresistible (build 8)TH_3628-1e-6952.87% (244) PUTATIVE short-chain dehydrogenase/reductase SDR

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2788cfabG1e-3936.03% (247) 3-ketoacyl-(acyl-carrier-protein) reductase
M. gilvum PYR-GCKMflv_1202-4e-7254.92% (244) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37RvRv2766cfabG1e-3936.03% (247) 3-ketoacyl-(acyl-carrier-protein) reductase
M. leprae Br4923MLBr_02565fabG3e-2233.46% (254) 3-ketoacyl-(acyl-carrier-protein) reductase
M. abscessus ATCC 19977MAB_4913c-9e-6549.17% (242) putative short chain dehydrogenase/reductase
M. marinum MMMAR_5310-2e-6953.47% (245) short-chain type dehydrogenase/reductase
M. avium 104MAV_0311-2e-7154.69% (245) short-chain dehydrogenase/reductase SDR
M. smegmatis MC2 155MSMEG_6340-1e-6854.51% (244) short-chain dehydrogenase/reductase SDR
M. ulcerans Agy99MUL_4384-7e-6953.06% (245) short-chain type dehydrogenase/reductase
M. vanbaalenii PYR-1Mvan_5605-4e-7054.29% (245) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


Mb2788c|M.bovis_AF2122/97           --------------------------------------------------
Rv2766c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_5310|M.marinum_M               --------------------------------------------------
MUL_4384|M.ulcerans_Agy99           --------------------------------------------------
MAV_0311|M.avium_104                --------------------------------------------------
MSMEG_6340|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1202|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5605|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4913c|M.abscessus_ATCC_199      --------------------------------------------------
TH_3708|M.thermoresistible__bu      --------------------------------------------------
MLBr_02565|M.leprae_Br4923          MAPKCSSDLFSQIVSSGPGSFVAKQLGVPRPETLRRYRPSDAPLCGSLLI
                                                                                      

Mb2788c|M.bovis_AF2122/97           --------------------------------------------------
Rv2766c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_5310|M.marinum_M               --------------------------------------------------
MUL_4384|M.ulcerans_Agy99           --------------------------------------------------
MAV_0311|M.avium_104                --------------------------------------------------
MSMEG_6340|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1202|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5605|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4913c|M.abscessus_ATCC_199      --------------------------------------------------
TH_3708|M.thermoresistible__bu      --------------------------------------------------
MLBr_02565|M.leprae_Br4923          GGDGRLVEPLRATLEKDYDLVSNNLGGRWTDSFGGLVFDATGITAPAELK
                                                                                      

Mb2788c|M.bovis_AF2122/97           --------------------------------------------------
Rv2766c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_5310|M.marinum_M               --------------------------------------------------
MUL_4384|M.ulcerans_Agy99           --------------------------------------------------
MAV_0311|M.avium_104                --------------------------------------------------
MSMEG_6340|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1202|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5605|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4913c|M.abscessus_ATCC_199      --------------------------------------------------
TH_3708|M.thermoresistible__bu      --------------------------------------------------
MLBr_02565|M.leprae_Br4923          GLHNFFTPLLRNLGRCARVVVIGTTPDATTSTDERIAQRALEGFSRSLGK
                                                                                      

Mb2788c|M.bovis_AF2122/97           --------------------------------------------------
Rv2766c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_5310|M.marinum_M               --------------------------------------------------
MUL_4384|M.ulcerans_Agy99           --------------------------------------------------
MAV_0311|M.avium_104                --------------------------------------------------
MSMEG_6340|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1202|M.gilvum_PYR-GCK          -----------------------------------------------MT-
Mvan_5605|M.vanbaalenii_PYR-1       -----------------------------------------------MTA
MAB_4913c|M.abscessus_ATCC_199      --------------------------------------------------
TH_3708|M.thermoresistible__bu      --------------------------------------------------
MLBr_02565|M.leprae_Br4923          ELRRGATVALVYLSPDAKPAATGLESTMRFILSAKSAYVNGQVFYVGAAD
                                                                                      

Mb2788c|M.bovis_AF2122/97           -----MTSLDLTGRTAIITGASRGIGLAIAQQLAAAGAHVVLTARRQE--
Rv2766c|M.tuberculosis_H37Rv        -----MTSLDLTGRTAIITGASRGIGLAIAQQLAAAGAHVVLTARRQE--
MMAR_5310|M.marinum_M               -MGYADQLFDLTDHVVLITGGSRGLGRQMAFAAARCGADVVIASRNLDNC
MUL_4384|M.ulcerans_Agy99           -MGYADQLFDLTDHVVLITGGSRGLGRQMAFAAARCGANVVIASRNLDNC
MAV_0311|M.avium_104                -MGYAEQLFDLADRVVLITGGSRGLGREMAFGAARCGADVVIASRNLDNC
MSMEG_6340|M.smegmatis_MC2_155      -MGYADQLFDLTDRVVLITGGSRGLGREMAFGAARCGADVIIASRNLDSC
Mflv_1202|M.gilvum_PYR-GCK          --GFADRLFDLTDRVVLITGGSRGLGREMAVAAAHCGADVIIASRKYDAC
Mvan_5605|M.vanbaalenii_PYR-1       SGGFADQLFDLTDRVVLVTGGSRGLGREMAFAAARCGADVVIASRKYEAC
MAB_4913c|M.abscessus_ATCC_199      ---------MLQDKVVVVTGGSRGLGRAMVRAFAAHGADVVIASRKIDSC
TH_3708|M.thermoresistible__bu      MTPDPLAAFRLDGKVALVTGGSRGLGFEMARAFAGAGADVIISSRDEESC
MLBr_02565|M.leprae_Br4923          STPPTNWDRPLENKVAIVTGAARGIGAAIAEVVARDGARVVAID--VESA
                                              * .:..::**.:**:*  :.   *  ** *:      :  

Mb2788c|M.bovis_AF2122/97           --AADEAAAQVGDRALGVGAHAVDEDAARRCVDLTLERFG-SVDILINNA
Rv2766c|M.tuberculosis_H37Rv        --AADEAAAQVGDRALGVGAHAVDEDAARRCVDLTLERFG-SVDILINNA
MMAR_5310|M.marinum_M               VATATEIESETGRCAMAYQVHVGRWDQLDGLVAASYERFG-KIDTLINNA
MUL_4384|M.ulcerans_Agy99           VATATEIESETGRSALAYQVHVGRWDQLDGLVAASYERFG-KIDTLINNA
MAV_0311|M.avium_104                VATAQQIEHETGRRAMAYQVHVGRWDQLDGLVEASYDRFG-KIDTLINNA
MSMEG_6340|M.smegmatis_MC2_155      VVTAEEIASETGRTAFPYSVHVGHWDELDGLVDAAYERFG-KVDVLVNNA
Mflv_1202|M.gilvum_PYR-GCK          VATAEEITAQTGRAALPYGVHVGRWDELDGLVDAAYARFG-KVDVLVNNA
Mvan_5605|M.vanbaalenii_PYR-1       VATADEIAAETGRAAFPYQVHVGRWDELDGLVDAAYDRFG-RVDVLVNNA
MAB_4913c|M.abscessus_ATCC_199      QELAAQVEAEHGRRALPVACNVSSWEQCDHLVDTVYREFG-RVDVLVNNA
TH_3708|M.thermoresistible__bu      RRAAEEIGRTFAVRAVPMPCHVGRWAELDALADRALATFG-HVDVLVNNA
MLBr_02565|M.leprae_Br4923          AEALDETANRVGGTTLSLDVTAD--DAVDKITEHLHDYQGGHADILVNNA
                                         :     .  :.     .         .       *   * *:***

Mb2788c|M.bovis_AF2122/97           GTNPAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMGEHGGAVVNT
Rv2766c|M.tuberculosis_H37Rv        GTNPAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMGEHGGAVVNT
MMAR_5310|M.marinum_M               GMSPLYDKLSDVTEKLFDAVLNLNLKGPFRLSALVGERMVAAGGGSIINV
MUL_4384|M.ulcerans_Agy99           GMSPLYDKLSDVTEKLFDAVLNLNLKGPFRLSALVGERMVAADGGSIINV
MAV_0311|M.avium_104                GMSPLYDKLTDVTEKLFDAVVNLNLKGPFRLSALVGERMVAAGRGSIINV
MSMEG_6340|M.smegmatis_MC2_155      GMSPLYESLSAVTEKLYDAVFNLNLKGPFRLSALIGERMVADGGGRIINV
Mflv_1202|M.gilvum_PYR-GCK          GMSPVYDKQSDVTEKLFDAVVNLNLKGPFRLSALIGERMVADGGGSIVNV
Mvan_5605|M.vanbaalenii_PYR-1       GMSPLYESLSAVTEKLFDSVVNLNLKGPFRLSVLVGDRMVADGGGSIINV
MAB_4913c|M.abscessus_ATCC_199      GLSPLYPSLDQVSEALFDKVIGVNLKGPFRLSASIATKMAAGAGGSIINI
TH_3708|M.thermoresistible__bu      GMSPLYDKVADITETMWEKTLAVNLRAPFRLTALLAPAMVDNGGGSVINL
MLBr_02565|M.leprae_Br4923          GIT-RDKLLANMDDCRWDAVLEVNLLAPQRLTEGLVGNGSISKGGRVIVL
                                    * .          .  :   . :** .*   :  :         * ::  

Mb2788c|M.bovis_AF2122/97           ASIGGMHQSPAMGMYNATKAALIHVTKQLALELSPR-IRVNAICPGVVRT
Rv2766c|M.tuberculosis_H37Rv        ASIGGMHQSPAMGMYNATKAALIHVTKQLALELSPR-IRVNAICPGVVRT
MMAR_5310|M.marinum_M               SSAGSLRPSADIIPYAAAKAGLNAMTEGLARAFGPT-VRVNTLMAGPFLT
MUL_4384|M.ulcerans_Agy99           SSAGSLRPSADIIPYAAAKAGLNAMTEGLARAFGPT-VRVNTLMAGPFLT
MAV_0311|M.avium_104                STAGSLRPTPDIVPYAASKAGLNAMTEALAKAFGPA-VRVNTLMAGPFLT
MSMEG_6340|M.smegmatis_MC2_155      SSSGSLRPDQYMLPYAAAKAGLNVLTEGLAKAYGPT-VRVNTLMAGPFLT
Mflv_1202|M.gilvum_PYR-GCK          STHGSLRPHPSFIPYAASKAGLNAMTEGLALAFGPS-VRVNTLMPGPFLT
Mvan_5605|M.vanbaalenii_PYR-1       STHGSIRPHPSFVPYAASKAGLNAMTEALALAYGPT-VRVNTLMPGPFLT
MAB_4913c|M.abscessus_ATCC_199      SSIEAVRPDATALPYAAAKAGLNALTLGLSHTFGPT-VRTNTIQCGLFNT
TH_3708|M.thermoresistible__bu      SSIGAVRPTADIVPYAAAKAGLNAMTAALAKEYGPH-VRVNAIMPGAFAT
MLBr_02565|M.leprae_Br4923          SSMAGIAGNRGQTNYATAKAGVIGLTQALAPGLAEKGITINAVAPGFIET
                                    ::  .:        * ::**.:  :*  *:   .   :  *::  * . *

Mb2788c|M.bovis_AF2122/97           RLAEALWKDHEDP-LAATIALGRIGEPADIASAVAFLVSDAASWITGETM
Rv2766c|M.tuberculosis_H37Rv        RLAEALWKDHEDP-LAATIALGRIGEPADIASAVAFLVSDAASWITGETM
MMAR_5310|M.marinum_M               DVSKAWNLDAATQNPFGHLTLRRAGNPPEIVGAALFLASDASSFTTGSIL
MUL_4384|M.ulcerans_Agy99           DVSKAWNLDAATQNPFGHLALRRAGNPPEIVGAALFLASDASSFTTGSIL
MAV_0311|M.avium_104                DVSRAWNLEAAQENPFRHLALQRAGDPREIVGAALFLASDASSFTTGSIL
MSMEG_6340|M.smegmatis_MC2_155      DVSRAWNMSGD---PFSHLALRRAGDPREIVGAALFLMSDASSFTTGSIV
Mflv_1202|M.gilvum_PYR-GCK          DISNAWNF-EGTDNPFRGSALQRAGQPAEIVGAALFLMSDASSFTTGSIV
Mvan_5605|M.vanbaalenii_PYR-1       DISDAWTFTDGDTNPFGHSALQRAGQPAEIVGAALFLMSDASSFTTGSIV
MAB_4913c|M.abscessus_ATCC_199      DIAAAWPEGFA-EALIPSIPLRRVGEPEDIVGAALYLASEASAYCTGTTI
TH_3708|M.thermoresistible__bu      DVSEYWSAEAVAR-VVDQTALGRIGDPREIVGTALYLASDAASFTSGAVI
MLBr_02565|M.leprae_Br4923          QMTAAIPLATR-EVGRRLNSLLQGGLPVDVAETIAYFAIPASNAVTGNVI
                                     ::                .* : * * ::. :  ::   *:   :*  :

Mb2788c|M.bovis_AF2122/97           IIDGGLLLGNALGFRAAPSTEH
Rv2766c|M.tuberculosis_H37Rv        IIDGGLLLGNALGFRAAPSTEH
MMAR_5310|M.marinum_M               RADGGIP---------------
MUL_4384|M.ulcerans_Agy99           RADGGIP---------------
MAV_0311|M.avium_104                RADGGIP---------------
MSMEG_6340|M.smegmatis_MC2_155      RADGGLP---------------
Mflv_1202|M.gilvum_PYR-GCK          RADGGSA---------------
Mvan_5605|M.vanbaalenii_PYR-1       RADGGIP---------------
MAB_4913c|M.abscessus_ATCC_199      RLDGGIL---------------
TH_3708|M.thermoresistible__bu      TVDGGRD---------------
MLBr_02565|M.leprae_Br4923          RVCGQAMLGA------------
                                       *