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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3605 | - | - | 100% (302) | NAD dependent epimerase/dehydratase family protein |
| M. thermoresistible (build 8) | TH_4244 | - | 5e-23 | 32.04% (284) | PUTATIVE putative Dehydrogenase/decarboxylase protein |
| M. thermoresistible (build 8) | TH_3670 | - | 3e-22 | 33.60% (247) | PUTATIVE short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2237c | ephD | 1e-21 | 30.22% (278) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_4152 | - | 1e-102 | 65.19% (293) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2214c | ephD | 1e-21 | 30.22% (278) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_00862 | ephD | 8e-24 | 30.55% (275) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_1305 | - | 2e-28 | 34.60% (263) | short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_3561 | - | 8e-29 | 32.62% (282) | oxidoreductase |
| M. avium 104 | MAV_1273 | - | 1e-102 | 66.67% (291) | NAD dependent epimerase/dehydratase family protein |
| M. smegmatis MC2 155 | MSMEG_3426 | - | 1e-25 | 32.45% (265) | short chain dehydrogenase |
| M. ulcerans Agy99 | MUL_2794 | - | 9e-29 | 32.06% (287) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_5466 | - | 1e-25 | 38.54% (192) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4152|M.gilvum_PYR-GCK --------------------------------------------------
MAV_1273|M.avium_104 --------------------------------------------------
TH_3605|M.thermoresistible__bu --------------------------------------------------
MMAR_3561|M.marinum_M --------------------------------------------------
MUL_2794|M.ulcerans_Agy99 --------------------------------------------------
MAB_1305|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_3426|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5466|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2237c|M.bovis_AF2122/97 MPATQQMS----RLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWD
Rv2214c|M.tuberculosis_H37Rv MPATQQMS----RLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWD
MLBr_00862|M.leprae_Br4923 MPATQSIHKVPHQFVESPDGVRLAIYQSGQPEGPAIVLVHGFPDSHVLWD
Mflv_4152|M.gilvum_PYR-GCK --------------------------------------------------
MAV_1273|M.avium_104 --------------------------------------------------
TH_3605|M.thermoresistible__bu --------------------------------------------------
MMAR_3561|M.marinum_M --------------------------------------------------
MUL_2794|M.ulcerans_Agy99 --------------------------------------------------
MAB_1305|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_3426|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5466|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2237c|M.bovis_AF2122/97 GVVPLLAERFRIVRYDNRGVGRSSVPKPISAYTMAHFADDFDAVIGELSP
Rv2214c|M.tuberculosis_H37Rv GVVPLLAERFRIVRYDNRGVGRSSVPKPISAYTMAHFADDFDAVIGELSP
MLBr_00862|M.leprae_Br4923 GVVPLLAKRFRIVRYDNRGVGQSSVPKPVSAYTMTRFADDFAAVIDELSP
Mflv_4152|M.gilvum_PYR-GCK --------------------------------------------------
MAV_1273|M.avium_104 --------------------------------------------------
TH_3605|M.thermoresistible__bu --------------------------------------------------
MMAR_3561|M.marinum_M --------------------------------------------------
MUL_2794|M.ulcerans_Agy99 --------------------------------------------------
MAB_1305|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_3426|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5466|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2237c|M.bovis_AF2122/97 GEPVHVLAHDWGSVGVWEYLRRPGASDRVASFTSVSGPSQDHLVNYVYGG
Rv2214c|M.tuberculosis_H37Rv GEPVHVLAHDWGSVGVWEYLRRPGASDRVASFTSVSGPSQDHLVNYVYGG
MLBr_00862|M.leprae_Br4923 DRPVHVLAHDWGSVGVWEYLSRSGASDRVASFTSVSGPSQDQLVDYILSG
Mflv_4152|M.gilvum_PYR-GCK --------------------------------------------------
MAV_1273|M.avium_104 --------------------------------------------------
TH_3605|M.thermoresistible__bu --------------------------------------------------
MMAR_3561|M.marinum_M --------------------------------------------------
MUL_2794|M.ulcerans_Agy99 --------------------------------------------------
MAB_1305|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_3426|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5466|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2237c|M.bovis_AF2122/97 LRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSSAAVRRNMV
Rv2214c|M.tuberculosis_H37Rv LRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSSAAVRRNMV
MLBr_00862|M.leprae_Br4923 LRRPWRPRTFARAVSQLFRLTYMVLFSIPVLVPMVLWIALSSATIRRTMV
Mflv_4152|M.gilvum_PYR-GCK --------------------------------------------------
MAV_1273|M.avium_104 --------------------------------------------------
TH_3605|M.thermoresistible__bu --------------------------------------------------
MMAR_3561|M.marinum_M --------------------------------------------------
MUL_2794|M.ulcerans_Agy99 --------------------------------------------------
MAB_1305|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_3426|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5466|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2237c|M.bovis_AF2122/97 GDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQ
Rv2214c|M.tuberculosis_H37Rv GDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQ
MLBr_00862|M.leprae_Br4923 DNISTDQIHHSATLARDAAHSVKTYPANYFRAFSGRRRGKGVPVVNVPVQ
Mflv_4152|M.gilvum_PYR-GCK --------------------------------------------------
MAV_1273|M.avium_104 --------------------------------------------------
TH_3605|M.thermoresistible__bu --------------------------------------------------
MMAR_3561|M.marinum_M --------------------------------------------------
MUL_2794|M.ulcerans_Agy99 --------------------------------------------------
MAB_1305|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_3426|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5466|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2237c|M.bovis_AF2122/97 LIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHD
Rv2214c|M.tuberculosis_H37Rv LIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHD
MLBr_00862|M.leprae_Br4923 LIVNTMDRYVRPYGYDATARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHD
Mflv_4152|M.gilvum_PYR-GCK -------------------MAERAGAQRRVALITGASRGLGFASAVRLYR
MAV_1273|M.avium_104 -------------------MAE-----PRSVVITGASRGLGFASALRMYR
TH_3605|M.thermoresistible__bu -------------------VTDRQPAGPRSVVITGASRGLGLASATHLYR
MMAR_3561|M.marinum_M -----------------------MTSTPPVALITGVSSGIGAAIAVRLAS
MUL_2794|M.ulcerans_Agy99 -----------------------MTSTPPVALITGVSSGIGAAIAVRLAS
MAB_1305|M.abscessus_ATCC_1997 ------------------------MSEHWTVLVTGASSGIGASAARIFAE
MSMEG_3426|M.smegmatis_MC2_155 ---------------------------MKTFFITGVSSGLGQAFANGALA
Mvan_5466|M.vanbaalenii_PYR-1 --------------------MPYPTDNPATWFVTGASRGLGAELVRQLLR
Mb2237c|M.bovis_AF2122/97 FADLADGKQPSRALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAR
Rv2214c|M.tuberculosis_H37Rv FADLADGKQPSRALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAR
MLBr_00862|M.leprae_Br4923 LADLVDGKQPSRALLRAQVGRSRDTFGDTLVSVTGAGSGIGRETALALAR
:**.. *:* .
Mflv_4152|M.gilvum_PYR-GCK EGWGVVAAMRTPERGMPRLR----EATGASEDDDRLVGVQLDLMDAASIA
MAV_1273|M.avium_104 EGWRVVAAMRTPDQGMPLLRRAIRDGTGQDPDDDRLIGVQLDLTDSASVA
TH_3605|M.thermoresistible__bu RGWRVVAAMRSVDAGMARLA----ETTGAAADDPRLIPVALDLTDAASIT
MMAR_3561|M.marinum_M AGFRVVGTSRAPQR--------------LAP-IPGVETLALDVTDDTAVR
MUL_2794|M.ulcerans_Agy99 AGFRVVGTSRAPQR--------------LAP-IPGVETLALDVTDDTAVR
MAB_1305|M.abscessus_ATCC_1997 RGHRVFGTSRNPDT--------------ITDRVPGVQYLRLDQTD----K
MSMEG_3426|M.smegmatis_MC2_155 AGHRVVGTVR-KDSDAAAFES---------TAPDRAHARQLDVTDDAAVT
Mvan_5466|M.vanbaalenii_PYR-1 RGDNVAATTRSAERLSAALAG---------VDTGRLLPLVVDLTDAAAVD
Mb2237c|M.bovis_AF2122/97 EGAEIVISDIDEATVKDTAAE-------IAARGGIAYPYVLDVSDAEAVE
Rv2214c|M.tuberculosis_H37Rv EGAEIVISDIDEATVKDTAAE-------IAARGGIAYPYVLDVSDAEAVE
MLBr_00862|M.leprae_Br4923 RGAEVVVSDIDEAAAKNTAAQ-------IVASGGVAYAYALDVSDAAAVE
* : : :* *
Mflv_4152|M.gilvum_PYR-GCK AAAKSIDEAVGAPYAVVHNAGISAAGVVEETDIELWERMFTTHVMGPVAL
MAV_1273|M.avium_104 AAAKAIEEAVGAPYAIVHNAGISAAGMVEETDTALWQRMFATSVLGPVAL
TH_3605|M.thermoresistible__bu AAAKEIEGSVGAPYAVVHNAGISAAGMVEETPLSLWEQMFATTVFGPVAL
MMAR_3561|M.marinum_M SVVSEVIDRTGRIDVLVNNAGLGIAGAAEESSIDQARSLFDTNFFGLIRL
MUL_2794|M.ulcerans_Agy99 SVVSEVIDRTGHIDVLVNNAGLGIAGAAEESSIDQARSLFDTNFFGLIRL
MAB_1305|M.abscessus_ATCC_1997 ASIAECVAQAGEVDILVNNAGESQIGALEDVSMDDFEKLYMTNVFGPVAL
MSMEG_3426|M.smegmatis_MC2_155 AVVAEVEKNIGPIDVVIANAGYGVEGIFEETPIAEMRAQFATNVFGVAAT
Mvan_5466|M.vanbaalenii_PYR-1 GAVAAALDRFGRLDVVVNNAGYGFLGAVEETTDAEIRQMLDVQVSGVWNV
Mb2237c|M.bovis_AF2122/97 AFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFDRVLAVNLGGVVNG
Rv2214c|M.tuberculosis_H37Rv AFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFDRVLAVNLGGVVNG
MLBr_00862|M.leprae_Br4923 AFAEQVSAKHGVPDIVVNNAGIGQAGRFLDTPPEEFDRVLAVNLGGVVNC
. * :: *** . * : . . *
Mflv_4152|M.gilvum_PYR-GCK TKALLPSMRAAGQG-RIVLVSSASGVRGQPATAPYSAAKGALERWGEAMA
MAV_1273|M.avium_104 TQALLPSMRAAGRG-RIVLVSSAAGVRGQPGTAPYSAAKGALERWGESLA
TH_3605|M.thermoresistible__bu TRELLPGMRRAGRG-RIVLVSSQQGVWGMPSTAPYSAAKGALERWAEAMA
MMAR_3561|M.marinum_M TNEVLPHMRRRGSG-RIINISSVLGFLPAPYAALYAASKHAVEGYTESLD
MUL_2794|M.ulcerans_Agy99 TNEVLPHMRRRGSG-RIINISSVLGFLPAPYAALYAASKHAVEGYTESLD
MAB_1305|M.abscessus_ATCC_1997 TKAVLPGMRERRRG-AVVMVGSMAGTLHVPFRSTYSSAKSALHTVADCLR
MSMEG_3426|M.smegmatis_MC2_155 LQAALPYLRERRKG-HLMAVTSMGGLMAVPGMSAYCASKFAVEGMLESIR
Mvan_5466|M.vanbaalenii_PYR-1 LRSAVPHLRAARSG-HIINVSSILGLTAVPGWGLYCAGKFALNGMSEALA
Mb2237c|M.bovis_AF2122/97 CRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCLR
Rv2214c|M.tuberculosis_H37Rv CRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCLR
MLBr_00862|M.leprae_Br4923 CRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCLR
. : * :: : * . . *.:.* * :.:
Mflv_4152|M.gilvum_PYR-GCK VEIAPFGLGVTILVTGTYDTDIITDAGTTDNRDLAGPYARIHQTMDSRGR
MAV_1273|M.avium_104 GEIAPFGLGVTVLVAGTYDTEIITDAGTTDDRNFSGPYARLHTTMNTRGR
TH_3605|M.thermoresistible__bu GEVNPFGIGVTVLVTGVYDTEIITDAGTTDCRDLQGVYARHHRTMDKRGR
MMAR_3561|M.marinum_M HELREYGVRALLVEPSYTRTDFESNMWEADTP--QAAYADNRAAVRAVVA
MUL_2794|M.ulcerans_Agy99 HELREYGVRALLVEPSYTRTDFESNMWEADTP--QAAYADNRAAVRAVVA
MAB_1305|M.abscessus_ATCC_1997 YEVAPFGITVSTVEPGVIATGIETRRNRIVPD--GSPYRDAFRTVDAAMA
MSMEG_3426|M.smegmatis_MC2_155 KEISGFGIHVTAIEPGSFRTDWAGRSMTRADRSIADYDELFEPIRAARLK
Mvan_5466|M.vanbaalenii_PYR-1 AELAGFGIRVTIVEPGYFRTDFLTTESLALPTAAGDAYPAIREMTEQHLQ
Mb2237c|M.bovis_AF2122/97 AELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFA
Rv2214c|M.tuberculosis_H37Rv AELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFA
MLBr_00862|M.leprae_Br4923 AELDAVGVGLTTICPGVIDTNIIQSTRIDTPTAKQERVRDRRGQLDMMFR
*: *: : .. *
Mflv_4152|M.gilvum_PYR-GCK FAMG-MARPPERFTDGLVKALEDTAAFRRHGVGPDASMLLLSNRILPAAG
MAV_1273|M.avium_104 LAVS-FARPPERFTDGLCKALDDRAPFRRRGVGPDASMLLAANRILPASG
TH_3605|M.thermoresistible__bu AAVAKAARPPEKFALALSKALDNPQPFVKRPAGPSARMLMIANRILPPAT
MMAR_3561|M.marinum_M DKIR-NAELPAVVADATYAAATDKRIKLRYPAGRHARQLALLKRIAPAAV
MUL_2794|M.ulcerans_Agy99 NKIR-NAELPAVVADATYAAAIDKRIKLRYPAGRHARQLALLKRIAPAAV
MAB_1305|M.abscessus_ATCC_1997 AREE-HGTATDELGRLVVDVALSPSPKPLYAKGSNAPIIMTAQRLLPARL
MSMEG_3426|M.smegmatis_MC2_155 ASGN-QLGNPVKAAEAVLAILDEPEPPAHLVLGSDALRLVGAARAAVDED
Mvan_5466|M.vanbaalenii_PYR-1 LQGS-QLGDPVKGAAAVIHVAVTGGGPLHQLLGSDAVSYAEAKIDALVAD
Mb2237c|M.bovis_AF2122/97 LRSY----GPDKVADAIVSAVKKKKP--IRPVAPEAYALYGISRVLPQAL
Rv2214c|M.tuberculosis_H37Rv LRSY----GPDKVADAIVSAVKKKKP--IRPVAPEAYALYGISRVLPQAL
MLBr_00862|M.leprae_Br4923 LRRY----GPDKVADTILSAIKKNKP--IRPVAPEAYALYGISRVLPQVL
. . *
Mflv_4152|M.gilvum_PYR-GCK MHHMSRVVLGIPRQGAMRDGAWPLTTAQRAMVAAAKVIPQPVMQRLVQWS
MAV_1273|M.avium_104 MHHLSRVVLGIPRQGSMRDGAWPLTHGQRAMVLVARVLPQPVLQRLAALA
TH_3605|M.thermoresistible__bu LHQMIRLSLGLPRFG-------RLTTREDTHA------------------
MMAR_3561|M.marinum_M LDNGIRKQTGLNSPRPTPVLAER---------------------------
MUL_2794|M.ulcerans_Agy99 LDNGIRKQTGLNSPRPTPVLAER---------------------------
MAB_1305|M.abscessus_ATCC_1997 FLKFLARMHGLKVR------------------------------------
MSMEG_3426|M.smegmatis_MC2_155 IRRWEELSRSTDFADGAQLAST----------------------------
Mvan_5466|M.vanbaalenii_PYR-1 VKAGRDLALTTDHR------------------------------------
Mb2237c|M.bovis_AF2122/97 RSTARLRVI-----------------------------------------
Rv2214c|M.tuberculosis_H37Rv RSTARLRVI-----------------------------------------
MLBr_00862|M.leprae_Br4923 RSTARIRVI-----------------------------------------
Mflv_4152|M.gilvum_PYR-GCK ---TRRAAGSGGGTSEG
MAV_1273|M.avium_104 GRFSSPKSAARQGDQEG
TH_3605|M.thermoresistible__bu -----------------
MMAR_3561|M.marinum_M -----------------
MUL_2794|M.ulcerans_Agy99 -----------------
MAB_1305|M.abscessus_ATCC_1997 -----------------
MSMEG_3426|M.smegmatis_MC2_155 -----------------
Mvan_5466|M.vanbaalenii_PYR-1 -----------------
Mb2237c|M.bovis_AF2122/97 -----------------
Rv2214c|M.tuberculosis_H37Rv -----------------
MLBr_00862|M.leprae_Br4923 -----------------