For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4244 | - | - | 100% (275) | putative Dehydrogenase/decarboxylase protein |
| M. thermoresistible (build 8) | TH_3670 | - | 2e-23 | 39.33% (178) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. thermoresistible (build 8) | TH_3427 | - | 5e-23 | 37.02% (208) | PUTATIVE short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2153c | - | 9e-19 | 30.33% (244) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_0295 | - | 3e-26 | 32.52% (246) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2129c | - | 9e-19 | 30.33% (244) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01740 | - | 2e-17 | 26.38% (254) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4335 | - | 1e-21 | 32.61% (184) | putative short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_4002 | - | 8e-41 | 38.38% (284) | dehydrogenase/decarboxylase protein |
| M. avium 104 | MAV_4982 | - | 1e-26 | 34.94% (249) | short-chain dehydrogenase/reductase SDR |
| M. smegmatis MC2 155 | MSMEG_0524 | - | 6e-27 | 40.54% (185) | short chain dehydrogenase |
| M. ulcerans Agy99 | MUL_3865 | - | 2e-37 | 38.89% (252) | dehydrogenase/decarboxylase protein |
| M. vanbaalenii PYR-1 | Mvan_5466 | - | 3e-27 | 35.41% (209) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2153c|M.bovis_AF2122/97 ----MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVM
Rv2129c|M.tuberculosis_H37Rv ----MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVM
MMAR_4002|M.marinum_M -----MSCTRQHVVVTGASSGIGRSTALRLASAGWHVYAGVRRAADGEAL
MUL_3865|M.ulcerans_Agy99 ------------MVVTGASSGIGRSTALRLASAGWHVYAGVRRAADGEAL
TH_4244|M.thermoresistible__bu --------------VTGAARGIGRSIVTQLADSGWDVVAGVRTEQDAENI
Mflv_0295|M.gilvum_PYR-GCK --------MSKVLLISGASRGLGRAITESALAAGHLVVAGVRATSSLS-D
MAV_4982|M.avium_104 --------MPKTWFITGSSRGLGRALTTAVLDHGDHVVATARRPAQLD-E
MSMEG_0524|M.smegmatis_MC2_155 ---------MTVWFITGASRGLGAQIARTALDHGADVAVGVRNPDLLPSD
Mvan_5466|M.vanbaalenii_PYR-1 --MPYPTDNPATWFVTGASRGLGAELVRQLLRRGDNVAATTRSAERLSAA
MAB_4335|M.abscessus_ATCC_1997 -MGTAVQLAGKVVAVTGGARGIGRAIATAFAAEGAKVAIGDIDKKLCENT
MLBr_01740|M.leprae_Br4923 MVKTAQYFVGKRCFVTGAASGIGRATALRLAAYGAELYLTDRHCDGLAQT
::*.: *:* . * :
Mb2153c|M.bovis_AF2122/97 GAELGGD--DRLLTVVADVRDLPAMQAAAETAVERFGGI--DVVVANAGI
Rv2129c|M.tuberculosis_H37Rv GAELGGD--DRLLTVVADVRDLPAMQAAAETAVERFGGI--DVVVANAGI
MMAR_4002|M.marinum_M QAASSG---GQLSPLLMDVTVAEQIDAAVGIVCEHIGAAGLDGLVDNAGI
MUL_3865|M.ulcerans_Agy99 QAASSG---GQLSPLLMDVTVAEQIDAAVGIVGEHIGAAGLDGLVDNAGI
TH_4244|M.thermoresistible__bu VALNP----ARITSVLLDVTEADHIAALD----RSLDGR-LDAVINNAGV
Mflv_0295|M.gilvum_PYR-GCK LATREP---DRLAVVELDVTDDRHARAAVATAVERFGRL--DVLVNNAGY
MAV_4982|M.avium_104 LVDRYG---PRIRACELDVTDRAAARRAIAAAVTAFGRI--DVVVNNAGY
MSMEG_0524|M.smegmatis_MC2_155 IA-------ERAFAVRLDVTHDADISAAVAAVVERFGRI--DVLVNNAGR
Mvan_5466|M.vanbaalenii_PYR-1 LAGVDT---GRLLPLVVDLTDAAAVDGAVAAALDRFGRL--DVVVNNAGY
MAB_4335|M.abscessus_ATCC_1997 AAEIGN----SAIGLPLDVTDHGSFEAFFDTIAATVGPV--DVIVNNAGI
MLBr_01740|M.leprae_Br4923 VSEARALGAQVPEYRALDISDYDEVAAFGADIHARHPSM--DIVMNIAGV
*: * :: **
Mb2153c|M.bovis_AF2122/97 ASYGSVLKVDPQAFRRVLDVNLLGNFHTVRATLPALIDRR--GYVLIVSS
Rv2129c|M.tuberculosis_H37Rv ASYGSVLKVDPQAFRRVLDVNLLGNFHTVRATLPALIDRR--GYVLIVSS
MMAR_4002|M.marinum_M GVASPVEMVPLDALRQQLEVNVVGQIAVTQAFLPLLRRAA--GRIVVIAS
MUL_3865|M.ulcerans_Agy99 GVASPVEMVPLDALRQQLQVNVVGQIAVTQAFLPLLRRAA--GRIVVIAS
TH_4244|M.thermoresistible__bu VVPGPLETVSPQDLRRQFDVNVIGHLAVTQAVLPRLRDSR--GRIVFISS
Mflv_0295|M.gilvum_PYR-GCK ANMSAIEDVDVDDFRAQIETNFFGVVNLTRAALPAMRRQRD-GHIVQISS
MAV_4982|M.avium_104 ANSAPVEEVSDDDFRAQVETNFFGVVNVTKAALPVLHRQRA-GHIVQISS
MSMEG_0524|M.smegmatis_MC2_155 GLLGALEEVTDAEARSLFDLNVFGLINVTRAVLPHMRASGG-GKLVHIGS
Mvan_5466|M.vanbaalenii_PYR-1 GFLGAVEETTDAEIRQMLDVQVSGVWNVLRSAVPHLRAARS-GHIINVSS
MAB_4335|M.abscessus_ATCC_1997 MPITPFDDESLESIQRQLDINVRGVMWGSQLAIKRMKPRGG-GVIVNIAS
MLBr_01740|M.leprae_Br4923 SVWGTVDRLTHDQWSNVVAINLMGPIHIIETFVPAILAAGRGGHLVNVSS
.. . :. * . : : * :: :.*
Mb2153c|M.bovis_AF2122/97 LAAFAAP-PGMAPYNMSKAGNEHFANALRLEVAHLGVSVGSAHMSWIDTA
Rv2129c|M.tuberculosis_H37Rv LAAFAAP-PGMAPYNMSKAGNEHFANALRLEVAHLGVSVGSAHMSWIDTA
MMAR_4002|M.marinum_M IGDRFTP-PFGGPLAASKAAIATLADALRQEVAPWGIKVVMIEPASINSG
MUL_3865|M.ulcerans_Agy99 IGDRFTP-PFGGPLAASKAAIATLADALRQEEAPWGIKVVMIEPASINSG
TH_4244|M.thermoresistible__bu LNGRISV-PLMGAYCASKFALEAVADALRMELAPWRIPVIVIQPTQTDTD
Mflv_0295|M.gilvum_PYR-GCK VGGRLVR-PGLAAYQSAKWAVTGFSGVLAVEVAPLGIKVTVLEPGGMRTD
MAV_4982|M.avium_104 VGGRVGGSPGIAAYQASKFAVAGFSEALAAEVAPLGIKVTIAEPGALRTE
MSMEG_0524|M.smegmatis_MC2_155 RSG-FEGEPGVGLYSASKFAVAGISEALSAELAPFGIQSMVVEPGVFRTD
Mvan_5466|M.vanbaalenii_PYR-1 ILG-LTAVPGWGLYCAGKFALNGMSEALAAELAGFGIRVTIVEPGYFRTD
MAB_4335|M.abscessus_ATCC_1997 AAG-KAGFPGLATYCATKHAVVGLSESLSLEYEPAGISVVCVMPGMVNTE
MLBr_01740|M.leprae_Br4923 AAG-LVALPWHAAYSASKYGLRGLSEVLRFDLARYRIGVSVVVPGAVRTP
* . * . .: * : : :
Mb2153c|M.bovis_AF2122/97 LVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCP
Rv2129c|M.tuberculosis_H37Rv LVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCP
MMAR_4002|M.marinum_M AADKLERDAKKAIDEFGADGARLYRDAYLGMVKAALSRERRGSPPTVVAD
MUL_3865|M.ulcerans_Agy99 AADKLERDAKKAIDEFGADGARLYRDAYLGMVKAALSRERRGSPPTVVAD
TH_4244|M.thermoresistible__bu MVRGADVMVEQTAAAMRPEHRDLYARHIGGMRKFIRQFHPSAVPADNVAA
Mflv_0295|M.gilvum_PYR-GCK WAG-SSMRIAPVREEYAA-------TVGAAAS-LSDPNVLGASDPAKVAG
MAV_4982|M.avium_104 WAG-SSMAVATVSPDYES-------TVGAMNRRRAGFNRNAPGDPARAAH
MSMEG_0524|M.smegmatis_MC2_155 FLDGSSLSMPANRIDAYDG-----TPAHDTLDWVDDANHTQLGDPVKGAA
Mvan_5466|M.vanbaalenii_PYR-1 FLTTESLALPTAAGDAYP-------AIREMTEQHLQLQGSQLGDPVKGAA
MAB_4335|M.abscessus_ATCC_1997 LISGLDTHWLLKTVEPED--------IANAVVKAVRRGVFPVFVPKMFGG
MLBr_01740|M.leprae_Br4923 LVDTIEIAGVDRQDPRFSRWVDRFRGHAVSAERAAEKILAGVAKNRYLIY
.
Mb2153c|M.bovis_AF2122/97 GWVALFRWL--KPLLSTRVGQRPIR-------------------------
Rv2129c|M.tuberculosis_H37Rv GWVALFRWL--KPLLSTRVGQRPIR-------------------------
MMAR_4002|M.marinum_M LVLKVLTMA--RPHARNVVGKD----------------------------
MUL_3865|M.ulcerans_Agy99 LVLKVLTMA--RPHARNVGGKGRQDVGDRVPLASDPGLGCAASQGFRASQ
TH_4244|M.thermoresistible__bu AVVNALTVR--RPRSRYIVGITHQ--------------------------
Mflv_0295|M.gilvum_PYR-GCK LLLDVIGMP--DPPRRLLVGPDAYR-------------------------
MAV_4982|M.avium_104 AIIEVVIAD--DPPLRLLLGSDALS-------------------------
MSMEG_0524|M.smegmatis_MC2_155 LIYEVANED--KLPRHLLLGRDAVE-------------------------
Mvan_5466|M.vanbaalenii_PYR-1 AVIHVAVTG--GGPLHQLLGSDAVS-------------------------
MAB_4335|M.abscessus_ATCC_1997 MYRTMSVLP--RSTGKFLTRKLGIQ-------------------------
MLBr_01740|M.leprae_Br4923 TSHDIRVLYGFKRLAWWPYGVVMKQVN-----------------------
Mb2153c|M.bovis_AF2122/97 --------------------------------------------------
Rv2129c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4002|M.marinum_M --------------------------------------------------
MUL_3865|M.ulcerans_Agy99 AGFAGNIQVRVKRKVVDAMAPMEMPNQDQVQALDPVFGKMAVELGQHAWS
TH_4244|M.thermoresistible__bu --------------------------------------------------
Mflv_0295|M.gilvum_PYR-GCK --------------------------------------------------
MAV_4982|M.avium_104 --------------------------------------------------
MSMEG_0524|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5466|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4335|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01740|M.leprae_Br4923 --------------------------------------------------
Mb2153c|M.bovis_AF2122/97 ---------------NTVAKLMPQMDAEVA--------------------
Rv2129c|M.tuberculosis_H37Rv ---------------NTVAKLMPQMDAEVA--------------------
MMAR_4002|M.marinum_M --------------ARMLATVSRWLPTP----------------------
MUL_3865|M.ulcerans_Agy99 LPQLTMRVKSFVFLAADLCTANLGFPLLTHVQMAGFNGVTPAECAAGIRH
TH_4244|M.thermoresistible__bu -------------FPRLQAIILPNLPPA----------------------
Mflv_0295|M.gilvum_PYR-GCK ---------------YATAAGRDLLAVDE---------------------
MAV_4982|M.avium_104 ---------------AALAKSHQQIAEAN---------------------
MSMEG_0524|M.smegmatis_MC2_155 ---------------RWRVKAAQMADDVT---------------------
Mvan_5466|M.vanbaalenii_PYR-1 ---------------YAEAKIDALVADVK---------------------
MAB_4335|M.abscessus_ATCC_1997 ---------------DFMLNAHGSDARK----------------------
MLBr_01740|M.leprae_Br4923 ---------------VVFTRALRPSPATMR--------------------
Mb2153c|M.bovis_AF2122/97 ------------ALGRFASAY---------TESLENS-------------
Rv2129c|M.tuberculosis_H37Rv ------------ALGRFASAY---------TESLENS-------------
MMAR_4002|M.marinum_M ------------ALDALRRR----------VFGLPKPGSLAISRSA----
MUL_3865|M.ulcerans_Agy99 LAPYVGYPTAAVALQQLRQQGPMGEEPAQAVEPQPLPGHIGEALDALDKD
TH_4244|M.thermoresistible__bu ------------ARDPLLRR----------LGSQP---------------
Mflv_0295|M.gilvum_PYR-GCK ------------RWRTLSMS----------TAADDVSPEQLDPLGSASR-
MAV_4982|M.avium_104 ------------RWAELSKS----------IDYPPVATPHR---AARSR-
MSMEG_0524|M.smegmatis_MC2_155 ------------AWEMKSLA----------TAHLA---------------
Mvan_5466|M.vanbaalenii_PYR-1 ------------AGRDLALT----------TDHR----------------
MAB_4335|M.abscessus_ATCC_1997 ------------AYEDRASHS---------GPSTE---------------
MLBr_01740|M.leprae_Br4923 ------------CVEPIKVG----------VYSQPRSGEGGKSGN-----
Mb2153c|M.bovis_AF2122/97 --------------------------------------------------
Rv2129c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4002|M.marinum_M --------------------------------------------------
MUL_3865|M.ulcerans_Agy99 FARFVTGQFHQRWAGDQRLTPRERALSCLAADVLNQTLDESFAMHVELAL
TH_4244|M.thermoresistible__bu --------------------------------------------------
Mflv_0295|M.gilvum_PYR-GCK --------------------------------------------------
MAV_4982|M.avium_104 --------------------------------------------------
MSMEG_0524|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5466|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4335|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01740|M.leprae_Br4923 --------------------------------------------------
Mb2153c|M.bovis_AF2122/97 ------------------------------------
Rv2129c|M.tuberculosis_H37Rv ------------------------------------
MMAR_4002|M.marinum_M ------------------------------------
MUL_3865|M.ulcerans_Agy99 AAGAGPAQLEAVLLLVAEYGIPKAWRAYRALDALTA
TH_4244|M.thermoresistible__bu ------------------------------------
Mflv_0295|M.gilvum_PYR-GCK ------------------------------------
MAV_4982|M.avium_104 ------------------------------------
MSMEG_0524|M.smegmatis_MC2_155 ------------------------------------
Mvan_5466|M.vanbaalenii_PYR-1 ------------------------------------
MAB_4335|M.abscessus_ATCC_1997 ------------------------------------
MLBr_01740|M.leprae_Br4923 ------------------------------------