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M. thermoresistible (build 8) TH_3670 (-)

annotation: short-chain dehydrogenase/reductase SDR
coordinates: 2187121 - 2187960
length: 280

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3670--100% (280)short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_3427-2e-2733.33% (237) PUTATIVE short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_4244-2e-2339.33% (178) PUTATIVE putative Dehydrogenase/decarboxylase protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1277c-6e-2430.34% (267) short-chain type dehydrogenase/reductase
M. gilvum PYR-GCKMflv_0295-1e-5443.28% (268) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37RvRv1245c-6e-2430.34% (267) short-chain type dehydrogenase/reductase
M. leprae Br4923MLBr_01094-5e-2230.29% (241) short chain alcohol dehydrogenase
M. abscessus ATCC 19977MAB_3919c-8e-2733.20% (247) putative short chain dehydrogenase/reductase
M. marinum MMMAR_1614-2e-4640.30% (268) short chain dehydrogenase
M. avium 104MAV_4982-2e-6247.21% (269) short-chain dehydrogenase/reductase SDR
M. smegmatis MC2 155MSMEG_1114-1e-11673.43% (271) short chain dehydrogenase
M. ulcerans Agy99MUL_3423-1e-4639.93% (268) short chain dehydrogenase
M. vanbaalenii PYR-1Mvan_0982-1e-12175.28% (271) short chain dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_1114|M.smegmatis_MC2_155      -----------MSEKVWFITGASRGFGREWAIAALDRGDKVAATARDTAT
Mvan_0982|M.vanbaalenii_PYR-1       MPGHPTGIDPGMTEKVWFITGASRGFGREWAIAALDRGDKVAATARDLST
TH_3670|M.thermoresistible__bu      MGSN------VWGSKVWFITGASRGFGREWAIAALDRGDRVAATARDVST
MMAR_1614|M.marinum_M               ------------MS-TWLITGCSTGLGRALAEAVIDAGHHTVATARSVGG
MUL_3423|M.ulcerans_Agy99           ------------MS-TWLITGCSTGLGRALAEAVIDAGHHTVATARSVGG
Mflv_0295|M.gilvum_PYR-GCK          ------------MSKVLLISGASRGLGRAITESALAAGHLVVAGVRATSS
MAV_4982|M.avium_104                ------------MPKTWFITGSSRGLGRALTTAVLDHGDHVVATARRPAQ
Mb1277c|M.bovis_AF2122/97           --------MEGFAGKVAVVTGAGSGIGQALAIELARSGAKVAISDVDTDG
Rv1245c|M.tuberculosis_H37Rv        --------MEGFAGKVAVVTGAGSGIGQALAIELARSGAKVAISDVDTDG
MLBr_01094|M.leprae_Br4923          --------MEGFAGKVAVVTGAGSGIGQALAIELARSGAKLAISDVDGEG
MAB_3919c|M.abscessus_ATCC_199      --------MKNFDNKVAVITGAGSGIGRSLALALAQRGARLALSDIDTAG
                                                   . .::*.. *:*:  :      *   .        

MSMEG_1114|M.smegmatis_MC2_155      LADLADKYGDA---LLPLQLDVDDRAADFAAVKQAHEHFGRLDIVVNNAG
Mvan_0982|M.vanbaalenii_PYR-1       LDDLTAKYGDA---LLPLTLDVTDRDADFAAVTQAHDHFGRLDIVVNNAG
TH_3670|M.thermoresistible__bu      LDDLRDRFGDA---VLAMTLDVTDRAADFAAVQRAHDHFGRLDIVVNNAG
MMAR_1614|M.marinum_M               VADLVQRSPER---VLPLALDITEPDQITAAVQAAQQRFGGIDVLVNNAG
MUL_3423|M.ulcerans_Agy99           VADLAQRSPER---VLPLALDITEPDQITAAMQAAQQRFGGIDVLVNNAG
Mflv_0295|M.gilvum_PYR-GCK          LSDLATREPDR---LAVVELDVTDDRHARAAVATAVERFGRLDVLVNNAG
MAV_4982|M.avium_104                LDELVDRYGPR---IRACELDVTDRAAARRAIAAAVTAFGRIDVVVNNAG
Mb1277c|M.bovis_AF2122/97           LADTEHRLKAISTPVKTDRLDVTEREAFLAYADAVNEHFGTVNQIYNNAG
Rv1245c|M.tuberculosis_H37Rv        LADTEHRLKAISTPVKTDRLDVTEREAFLAYADAVNEHFGTVNQIYNNAG
MLBr_01094|M.leprae_Br4923          LAQTEGQLKAIGASARTDRLDVTEREAFLTYADVVHENFGKVNQIYNNAG
MAB_3919c|M.abscessus_ATCC_199      VADTAGRCEKAGATAIPFELDVADRAAVYAHAADVKNEFGQVNLVFNNAG
                                    : :   :            **: :          .   ** :: : ****

MSMEG_1114|M.smegmatis_MC2_155      YGQFGFIEELSEAEARAQIETNLFGALWVTQAALPILRAQRSGHIIQVSS
Mvan_0982|M.vanbaalenii_PYR-1       YGQFGFVEELSEQEARAQIDTNVFGALWITQAALPYLRAQRSGHLIQVSS
TH_3670|M.thermoresistible__bu      YGHFGFVEELTETEVRDQMETNFFGALWVTQAALPYLRRQRSGHIIQVSS
MMAR_1614|M.marinum_M               YGYRAAVEEGDDAEVRDLFETHFFGTVALIKAVLPDMRARRSGAIVNISS
MUL_3423|M.ulcerans_Agy99           YGYRAAVEEGDDAEVRDLFETHFFGTVALIKAVLPDMRARRSGAIVNISS
Mflv_0295|M.gilvum_PYR-GCK          YANMSAIEDVDVDDFRAQIETNFFGVVNLTRAALPAMRRQRDGHIVQISS
MAV_4982|M.avium_104                YANSAPVEEVSDDDFRAQVETNFFGVVNVTKAALPVLHRQRAGHIVQISS
Mb1277c|M.bovis_AF2122/97           IAFTGDIEVSQFKDIERVMDVDFWGVVNGTKAFLPHLIASGDGHVINISS
Rv1245c|M.tuberculosis_H37Rv        IAFTGDIEVSQFKDIERVMDVDFWGVVNGTKAFLPHLIASGDGHVINISS
MLBr_01094|M.leprae_Br4923          IAFTGDVEVSHFKDIERVMDVDYWGVVNGTKAFLPYLISSGDGHVINISS
MAB_3919c|M.abscessus_ATCC_199      VALSADVKDMEWDDFDWLMNINFWGVAHGTKAFLPHLIESGDGHIVNVSS
                                     .  . ::     :    .: . :*.    :* ** :     * ::::**

MSMEG_1114|M.smegmatis_MC2_155      IGG-ISAFPLVGMYHASKWALEGFSQSLAQEVEGFG--INVTLIEPGGFS
Mvan_0982|M.vanbaalenii_PYR-1       IGG-IVAFPNLGIYHASKWALEGFSQALAQEVAEFG--IHVTLIEPGGYS
TH_3670|M.thermoresistible__bu      IGG-VSAFADLGAYHASKWALEGLSQSLSLEVAPFG--IHVTLIEPGGYA
MMAR_1614|M.marinum_M               IAVALTP-VGSGYYAAAKAAMEGMSGALHGELAPLG--ISVTVVEPGAFR
MUL_3423|M.ulcerans_Agy99           IAVALTP-VGSGYYAAAKAAMEGMSGALHGELAPLG--ISVTVVEPGAFR
Mflv_0295|M.gilvum_PYR-GCK          VGGRLVR-PGLAAYQSAKWAVTGFSGVLAVEVAPLG--IKVTVLEPGGMR
MAV_4982|M.avium_104                VGGRVGGSPGIAAYQASKFAVAGFSEALAAEVAPLG--IKVTIAEPGALR
Mb1277c|M.bovis_AF2122/97           VFG-LFSAPGQAAYNSAKFAVRGFTEALRQEMALAGHPVKVTTVHPGGVK
Rv1245c|M.tuberculosis_H37Rv        VFG-LFSAPGQAAYNSAKFAVRGFTEALRQEMALAGHPVKVTTVHPGGVK
MLBr_01094|M.leprae_Br4923          VFG-LFSVPGQAAYNSAKFAVRGFTEALREEMALAGRPVNVTTVYPGGIK
MAB_3919c|M.abscessus_ATCC_199      VFG-LMGIPSQSAYNAAKFAVRGFTESLRQEIRAAKFPVGVTCVHPGGIK
                                    :   :      . * ::* *: *::  *  *:      : **   **.  

MSMEG_1114|M.smegmatis_MC2_155      TDWAGSSAKHAT-PIADYDELRDATNTARSQRNS-KPGDPKASASAVLKI
Mvan_0982|M.vanbaalenii_PYR-1       TDWAGASAKRAT-ALPAYAEAHAATERTRQARTA-RPGDPQASARALLTV
TH_3670|M.thermoresistible__bu      TDWGGSSARRSA-TMPEYAESRAEADRVRSQRVA-RPGDPKASAAALLKV
MMAR_1614|M.marinum_M               TDFAGRSLVQSTRMINDYAATAGQRRKENDTMHGNQPGDPAKAAAAIITA
MUL_3423|M.ulcerans_Agy99           TDFAGRSLVQSTRMINDYAATAGQRRKENDTMHGNQPGDPAKAAAAIITA
Mflv_0295|M.gilvum_PYR-GCK          TDWAGSSMRIAP-VREEYAATVGAAAS-LSDPNVLGASDPAKVAGLLLDV
MAV_4982|M.avium_104                TEWAGSSMAVAT-VSPDYESTVGAMNRRRAGFNRNAPGDPARAAHAIIEV
Mb1277c|M.bovis_AF2122/97           TAIAR--------NAT-AAEGLDQAELAETFDKRVAHLSPQRAAQIILTG
Rv1245c|M.tuberculosis_H37Rv        TAIAR--------NAT-AAEGLDQAELAETFDKRVAHLSPQRAAQIILTG
MLBr_01094|M.leprae_Br4923          TAIAR--------NAT-AAEGLDVSKIASRFDTWVAHTSPQHAARIILKA
MAB_3919c|M.abscessus_ATCC_199      TNIAS--------SARGIPDGVDRETVRKGFQ-LMAITRPDSAARIILRG
                                    *  .                                   *   *  ::  

MSMEG_1114|M.smegmatis_MC2_155      VDAEKPPLRVFFGERPLEIAKADYERRIKLWEEWQPVAVEAQG-------
Mvan_0982|M.vanbaalenii_PYR-1       VDAPEPPLRVFFGELPLELARADYESRLANWEKWQPVAIEAQG-------
TH_3670|M.thermoresistible__bu      VDAEKPPLRVFFGELPLQIVNADYQSRLQTWEEWQPIAVLAQG-------
MMAR_1614|M.marinum_M               VESPAPPAFLLLGPDALMAYRHIAQRRDVEITDWEQLTAGTNLTP-----
MUL_3423|M.ulcerans_Agy99           VESPAPPAFLLLGPDALMAYRHIAQRRDVEITDWEQLTAGTNLTP-----
Mflv_0295|M.gilvum_PYR-GCK          IGMPDPPRRLLVGPDAYRYATAAGRDLLAVDERWRTLSMSTAADDVSPEQ
MAV_4982|M.avium_104                VIADDPPLRLLLGSDALSAALAKSHQQIAEANRWAELSKSIDYPPVATPH
Mb1277c|M.bovis_AF2122/97           VAKNKA--RVLVGVDAKVLDLVVRLTG-SGYQRIFP------------II
Rv1245c|M.tuberculosis_H37Rv        VAKNKA--RVLVGVDAKVLDLVVRLTG-SGYQRIFP------------II
MLBr_01094|M.leprae_Br4923          VRKKKA--RVLVGPDAKVANVVVRFSGGAGYQRLFA------------QV
MAB_3919c|M.abscessus_ATCC_199      VEKNRP--RVLIGPDARVFDAIPRIIG-PRYEDLMAPFYGMGRYGIGKKI
                                    :    .   ::.*  .                                  

MSMEG_1114|M.smegmatis_MC2_155      ---------
Mvan_0982|M.vanbaalenii_PYR-1       ---------
TH_3670|M.thermoresistible__bu      ---------
MMAR_1614|M.marinum_M               ---------
MUL_3423|M.ulcerans_Agy99           ---------
Mflv_0295|M.gilvum_PYR-GCK          LDPLGSASR
MAV_4982|M.avium_104                R---AARSR
Mb1277c|M.bovis_AF2122/97           TGRLIPRPR
Rv1245c|M.tuberculosis_H37Rv        TGRLIPRPR
MLBr_01094|M.leprae_Br4923          ASRLILNQR
MAB_3919c|M.abscessus_ATCC_199      AGRFGIEL-