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KTFFITGVSSGLGQAFANGALAAGHRVVGTVRKDSDAAAFESTAPDRAHARQLDVTDDAAVTAVVAEVEK NIGPIDVVIANAGYGVEGIFEETPIAEMRAQFATNVFGVAATLQAALPYLRERRKGHLMAVTSMGGLMAV PGMSAYCASKFAVEGMLESIRKEISGFGIHVTAIEPGSFRTDWAGRSMTRADRSIADYDELFEPIRAARL KASGNQLGNPVKAAEAVLAILDEPEPPAHLVLGSDALRLVGAARAAVDEDIRRWEELSRSTDFADGAQLA ST*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3426 | - | - | 100% (283) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_2026 | - | 2e-59 | 43.07% (274) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_1114 | - | 2e-52 | 43.61% (266) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1914c | - | 8e-21 | 32.35% (238) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_0295 | - | 2e-49 | 40.94% (276) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1882c | - | 8e-21 | 32.35% (238) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_00862 | ephD | 4e-21 | 32.22% (239) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_1305 | - | 8e-27 | 32.69% (260) | short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_1614 | - | 3e-51 | 38.83% (273) | short chain dehydrogenase |
| M. avium 104 | MAV_1976 | - | 1e-112 | 69.86% (282) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_3670 | - | 2e-46 | 39.07% (279) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_3423 | - | 3e-51 | 38.46% (273) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_0982 | - | 3e-49 | 41.73% (266) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_3426|M.smegmatis_MC2_155 --------------------------------------------------
MAV_1976|M.avium_104 --------------------------------------------------
MMAR_1614|M.marinum_M --------------------------------------------------
MUL_3423|M.ulcerans_Agy99 --------------------------------------------------
TH_3670|M.thermoresistible__bu --------------------------------------------------
Mvan_0982|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0295|M.gilvum_PYR-GCK --------------------------------------------------
Mb1914c|M.bovis_AF2122/97 --------------------------------------------------
Rv1882c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1305|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00862|M.leprae_Br4923 MPATQSIHKVPHQFVESPDGVRLAIYQSGQPEGPAIVLVHGFPDSHVLWD
MSMEG_3426|M.smegmatis_MC2_155 --------------------------------------------------
MAV_1976|M.avium_104 --------------------------------------------------
MMAR_1614|M.marinum_M --------------------------------------------------
MUL_3423|M.ulcerans_Agy99 --------------------------------------------------
TH_3670|M.thermoresistible__bu --------------------------------------------------
Mvan_0982|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0295|M.gilvum_PYR-GCK --------------------------------------------------
Mb1914c|M.bovis_AF2122/97 --------------------------------------------------
Rv1882c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1305|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00862|M.leprae_Br4923 GVVPLLAKRFRIVRYDNRGVGQSSVPKPVSAYTMTRFADDFAAVIDELSP
MSMEG_3426|M.smegmatis_MC2_155 --------------------------------------------------
MAV_1976|M.avium_104 --------------------------------------------------
MMAR_1614|M.marinum_M --------------------------------------------------
MUL_3423|M.ulcerans_Agy99 --------------------------------------------------
TH_3670|M.thermoresistible__bu --------------------------------------------------
Mvan_0982|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0295|M.gilvum_PYR-GCK --------------------------------------------------
Mb1914c|M.bovis_AF2122/97 --------------------------------------------------
Rv1882c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1305|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00862|M.leprae_Br4923 DRPVHVLAHDWGSVGVWEYLSRSGASDRVASFTSVSGPSQDQLVDYILSG
MSMEG_3426|M.smegmatis_MC2_155 --------------------------------------------------
MAV_1976|M.avium_104 --------------------------------------------------
MMAR_1614|M.marinum_M --------------------------------------------------
MUL_3423|M.ulcerans_Agy99 --------------------------------------------------
TH_3670|M.thermoresistible__bu --------------------------------------------------
Mvan_0982|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0295|M.gilvum_PYR-GCK --------------------------------------------------
Mb1914c|M.bovis_AF2122/97 --------------------------------------------------
Rv1882c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1305|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00862|M.leprae_Br4923 LRRPWRPRTFARAVSQLFRLTYMVLFSIPVLVPMVLWIALSSATIRRTMV
MSMEG_3426|M.smegmatis_MC2_155 --------------------------------------------------
MAV_1976|M.avium_104 --------------------------------------------------
MMAR_1614|M.marinum_M --------------------------------------------------
MUL_3423|M.ulcerans_Agy99 --------------------------------------------------
TH_3670|M.thermoresistible__bu --------------------------------------------------
Mvan_0982|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0295|M.gilvum_PYR-GCK --------------------------------------------------
Mb1914c|M.bovis_AF2122/97 --------------------------------------------------
Rv1882c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1305|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00862|M.leprae_Br4923 DNISTDQIHHSATLARDAAHSVKTYPANYFRAFSGRRRGKGVPVVNVPVQ
MSMEG_3426|M.smegmatis_MC2_155 --------------------------------------------------
MAV_1976|M.avium_104 --------------------------------------------------
MMAR_1614|M.marinum_M --------------------------------------------------
MUL_3423|M.ulcerans_Agy99 --------------------------------------------------
TH_3670|M.thermoresistible__bu --------------------------------------------------
Mvan_0982|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0295|M.gilvum_PYR-GCK --------------------------------------------------
Mb1914c|M.bovis_AF2122/97 --------------------------------------------------
Rv1882c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1305|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00862|M.leprae_Br4923 LIVNTMDRYVRPYGYDATARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHD
MSMEG_3426|M.smegmatis_MC2_155 ---------------------------MKTFFITGVSSGLGQAFANGALA
MAV_1976|M.avium_104 --------------------------MPKTFFITGVSSGLGRALAHGALE
MMAR_1614|M.marinum_M ---------------------------MSTWLITGCSTGLGRALAEAVID
MUL_3423|M.ulcerans_Agy99 ---------------------------MSTWLITGCSTGLGRALAEAVID
TH_3670|M.thermoresistible__bu --------------MGSNVWG------SKVWFITGASRGFGREWAIAALD
Mvan_0982|M.vanbaalenii_PYR-1 --------------MPGHPTGIDPGMTEKVWFITGASRGFGREWAIAALD
Mflv_0295|M.gilvum_PYR-GCK --------------------------MSKVLLISGASRGLGRAITESALA
Mb1914c|M.bovis_AF2122/97 ---------------------------MKAIFITGAGSGMGREGATLFHA
Rv1882c|M.tuberculosis_H37Rv ---------------------------MKAIFITGAGSGMGREGATLFHA
MAB_1305|M.abscessus_ATCC_1997 ------------------------MSEHWTVLVTGASSGIGASAARIFAE
MLBr_00862|M.leprae_Br4923 LADLVDGKQPSRALLRAQVGRSRDTFGDTLVSVTGAGSGIGRETALALAR
::* . *:* :
MSMEG_3426|M.smegmatis_MC2_155 AGHRVVGTVRKDSDAAAF---ESTAPDRAHARQLDVTDDAAVTAVVAEVE
MAV_1976|M.avium_104 AGHTVIGTVRKTADLAPF---EALD-AKAHGRILDVTDHAAVIDTVAEAE
MMAR_1614|M.marinum_M AGHHTVATARSVGGVADL---VQRSPERVLPLALDITEPDQITAAVQAAQ
MUL_3423|M.ulcerans_Agy99 AGHHTVATARSVGGVADL---AQRSPERVLPLALDITEPDQITAAMQAAQ
TH_3670|M.thermoresistible__bu RGDRVAATARDVSTLDDL---RDRFGDAVLAMTLDVTDRAADFAAVQRAH
Mvan_0982|M.vanbaalenii_PYR-1 RGDKVAATARDLSTLDDL---TAKYGDALLPLTLDVTDRDADFAAVTQAH
Mflv_0295|M.gilvum_PYR-GCK AGHLVVAGVRATSSLSDL---ATREPDRLAVVELDVTDDRHARAAVATAV
Mb1914c|M.bovis_AF2122/97 NGWRVGAIDRNEDGLAALR--VQLGAERLWARAVDVTDKAALEGALADFC
Rv1882c|M.tuberculosis_H37Rv NGWRVGAIDRNEDGLAALR--VQLGAERLWARAVDVTDKAALEGALADFC
MAB_1305|M.abscessus_ATCC_1997 RGHRVFGTSRNPDTITDR-------VPGVQYLRLDQTDKASIAECVAQAG
MLBr_00862|M.leprae_Br4923 RGAEVVVSDIDEAAAKNTAAQIVASGGVAYAYALDVSDAAAVEAFAEQVS
* . :* ::
MSMEG_3426|M.smegmatis_MC2_155 KN--IGPIDVVIANAGYGVEGIFEETPIAEMRAQFATNVFGVAATLQAAL
MAV_1976|M.avium_104 AS--IGPIDVLIANAGYGLEGVFEETPLSEVRAQFETNFFGAAATVQSVL
MMAR_1614|M.marinum_M QR--FGGIDVLVNNAGYGYRAAVEEGDDAEVRDLFETHFFGTVALIKAVL
MUL_3423|M.ulcerans_Agy99 QR--FGGIDVLVNNAGYGYRAAVEEGDDAEVRDLFETHFFGTVALIKAVL
TH_3670|M.thermoresistible__bu DH--FGRLDIVVNNAGYGHFGFVEELTETEVRDQMETNFFGALWVTQAAL
Mvan_0982|M.vanbaalenii_PYR-1 DH--FGRLDIVVNNAGYGQFGFVEELSEQEARAQIDTNVFGALWITQAAL
Mflv_0295|M.gilvum_PYR-GCK ER--FGRLDVLVNNAGYANMSAIEDVDVDDFRAQIETNFFGVVNLTRAAL
Mb1914c|M.bovis_AF2122/97 AGNVGGGLDMMWNNAGIGEGGWFEDVPYEAAVRVVDVNFKAVLTGAYAAL
Rv1882c|M.tuberculosis_H37Rv AGNVGGGLDMMWNNAGIGEGGWFEDVPYEAAVRVVDVNFKAVLTGAYAAL
MAB_1305|M.abscessus_ATCC_1997 EV------DILVNNAGESQIGALEDVSMDDFEKLYMTNVFGPVALTKAVL
MLBr_00862|M.leprae_Br4923 AK--HGVPDIVVNNAGIGQAGRFLDTPPEEFDRVLAVNLGGVVNCCRAFG
*:: *** . . . : .:. . :
MSMEG_3426|M.smegmatis_MC2_155 PYLRER-RKGHLMAVTSMGGLMAVPGMSAYCASKFAVEGMLESIRKEISG
MAV_1976|M.avium_104 PYMRKR-RGGHIMAVTSMGGLMTVPGLSVYCASKYALEGLLESIGKEVAG
MMAR_1614|M.marinum_M PDMRAR-RSGAIVNISSIAVALTPVGSGYYAAAKAAMEGMSGALHGELAP
MUL_3423|M.ulcerans_Agy99 PDMRAR-RSGAIVNISSIAVALTPVGSGYYAAAKAAMEGMSGALHGELAP
TH_3670|M.thermoresistible__bu PYLRRQ-RSGHIIQVSSIGGVSAFADLGAYHASKWALEGLSQSLSLEVAP
Mvan_0982|M.vanbaalenii_PYR-1 PYLRAQ-RSGHLIQVSSIGGIVAFPNLGIYHASKWALEGFSQALAQEVAE
Mflv_0295|M.gilvum_PYR-GCK PAMRRQ-RDGHIVQISSVGGRLVRPGLAAYQSAKWAVTGFSGVLAVEVAP
Mb1914c|M.bovis_AF2122/97 PYLKKA-PGSLMFSTSSSSGTYGMPRIAVYSATKHAVKGLTEALSVEWQR
Rv1882c|M.tuberculosis_H37Rv PYLKKA-PGSLMFSTSSSSGTYGMPRIAVYSATKHAVKGLTEALSVEWQR
MAB_1305|M.abscessus_ATCC_1997 PGMRER-RRGAVVMVGSMAGTLHVPFRSTYSSAKSALHTVADCLRYEVAP
MLBr_00862|M.leprae_Br4923 QRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCLRAELDA
: . :. * . . * ::* * . : *
MSMEG_3426|M.smegmatis_MC2_155 FGIHVTAIEPGSFRTDWAGRSMTRADRSIADYDELFEPIRAARLKASGNQ
MAV_1976|M.avium_104 FGIHVTAIEPGSFRTDWAGRSMVRAERAIDDYDAVFEPIRSARLRANGNQ
MMAR_1614|M.marinum_M LGISVTVVEPGAFRTDFAGRSLVQSTRMINDYAATAGQRRKENDTMHGNQ
MUL_3423|M.ulcerans_Agy99 LGISVTVVEPGAFRTDFAGRSLVQSTRMINDYAATAGQRRKENDTMHGNQ
TH_3670|M.thermoresistible__bu FGIHVTLIEPGGYATDWGGSSARRSA-TMPEYAESRAEADRVR-SQRVAR
Mvan_0982|M.vanbaalenii_PYR-1 FGIHVTLIEPGGYSTDWAGASAKRAT-ALPAYAEAHAATERTR-QARTAR
Mflv_0295|M.gilvum_PYR-GCK LGIKVTVLEPGGMRTDWAGSSMRIAP-VREEYAATVGAAASLS-DPNVLG
Mb1914c|M.bovis_AF2122/97 HGVRVADVLPGLIDTAILTSTRQHSD--EGPYTISAEQIRAAAPKKGMFR
Rv1882c|M.tuberculosis_H37Rv HGVRVADVLPGLIDTAILTSTRQHSD--EGPYTISAEQIRAAAPKKGMFR
MAB_1305|M.abscessus_ATCC_1997 FGITVSTVEPGVIATGIETRRNRIVP-DGSPYRDAFRTVDAAMAAREEHG
MLBr_00862|M.leprae_Br4923 VGVGLTTICPGVIDTNIIQSTRIDTP---TAKQERVRDRRGQLDMMFRLR
*: :: : ** *
MSMEG_3426|M.smegmatis_MC2_155 LGNPVKAAEAVLAILDEPEPPAHLVLGSDALRLVGAARAAVDEDIRRWEE
MAV_1976|M.avium_104 LGDPAKAATAILTAVEAAQPPRHLLLGSDALRLIRAGRDAVDADIAAWES
MMAR_1614|M.marinum_M PGDPAKAAAAIITAVESPAPPAFLLLGPDALMAYRHIAQRRDVEITDWEQ
MUL_3423|M.ulcerans_Agy99 PGDPAKAAAAIITAVESPAPPAFLLLGPDALMAYRHIAQRRDVEITDWEQ
TH_3670|M.thermoresistible__bu PGDPKASAAALLKVVDAEKPPLRVFFGELPLQIVNADYQSRLQTWEEWQP
Mvan_0982|M.vanbaalenii_PYR-1 PGDPQASARALLTVVDAPEPPLRVFFGELPLELARADYESRLANWEKWQP
Mflv_0295|M.gilvum_PYR-GCK ASDPAKVAGLLLDVIGMPDPPRRLLVGPDAYRYATAAGRDLLAVDERWRT
Mb1914c|M.bovis_AF2122/97 LMPSSSVAEAAWRAYQHP--TRLHWYVPRSIRWIDRLKGVSPEFVRRHIA
Rv1882c|M.tuberculosis_H37Rv LMPSSSVAEAAWRAYQHP--TRLHWYVPRSIRWIDRLKGVSPEFVRRHIA
MAB_1305|M.abscessus_ATCC_1997 -TATDELGRLVVDVALSPSPKPLYAKGSNAPIIMTAQRLLPARLFLKFLA
MLBr_00862|M.leprae_Br4923 RYGPDKVADTILSAIKKNKPIRPVAPEAYALYGISRVLPQVLRSTARIRV
. . .
MSMEG_3426|M.smegmatis_MC2_155 LSRSTDFADGAQLAST-------
MAV_1976|M.avium_104 LSRSTDFPDGHQIAAS-------
MMAR_1614|M.marinum_M LTAGTNLTP--------------
MUL_3423|M.ulcerans_Agy99 LTAGTNLTP--------------
TH_3670|M.thermoresistible__bu IAVLAQG----------------
Mvan_0982|M.vanbaalenii_PYR-1 VAIEAQG----------------
Mflv_0295|M.gilvum_PYR-GCK LSMSTAADDVSPEQLDPLGSASR
Mb1914c|M.bovis_AF2122/97 KSLATLEPKRK------------
Rv1882c|M.tuberculosis_H37Rv KSLATLEPKRK------------
MAB_1305|M.abscessus_ATCC_1997 RMHGLKVR---------------
MLBr_00862|M.leprae_Br4923 I----------------------