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M. thermoresistible (build 8) TH_3237 (-)

annotation: short-chain dehydrogenase/reductase SDR
coordinates: 3956486 - 3957322
length: 279

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3237--100% (279)short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_3962-3e-8153.99% (276) PUTATIVE short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_3018-9e-8052.77% (271) PUTATIVE carveol dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2771-3e-6851.82% (274) 3-ketoacyl-(acyl-carrier-protein) reductase
M. gilvum PYR-GCKMflv_2430-1e-14489.21% (278) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37RvRv2750-3e-6851.82% (274) 3-ketoacyl-(acyl-carrier-protein) reductase
M. leprae Br4923MLBr_01807fabG11e-2435.12% (205) 3-oxoacyl-
M. abscessus ATCC 19977MAB_0072c-6e-8055.27% (275) putative short chain dehydrogenase/reductase
M. marinum MMMAR_4754-1e-12777.78% (279) short-chain type dehydrogenase/reductase
M. avium 104MAV_0896-1e-13381.56% (282) carveol dehydrogenase ((+)-trans-carveol dehydrogenase)
M. smegmatis MC2 155MSMEG_6031-1e-13482.08% (279) carveol dehydrogenase
M. ulcerans Agy99MUL_3392fabG3e-6448.04% (281) 3-ketoacyl-(acyl-carrier-protein) reductase
M. vanbaalenii PYR-1Mvan_4222-1e-14389.21% (278) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


Mb2771|M.bovis_AF2122/97            ---MIDRPLEGKVAFITGAARGLGRAHAVR---LAADGANIIAVDICEQI
Rv2750|M.tuberculosis_H37Rv         ---MIDRPLEGKVAFITGAARGLGRAHAVR---LAADGANIIAVDICEQI
MUL_3392|M.ulcerans_Agy99           MSRPLDGPLSGRVAFITGAARGQGRAHALR---LARDGADVIAVDLCDQI
Mflv_2430|M.gilvum_PYR-GCK          ----MAGRVEGKVAFITGAARGQGRAHAVR---LAEEGADIIAVDICKQI
Mvan_4222|M.vanbaalenii_PYR-1       ----MAGRVEGKVAFITGAARGQGRAHAVR---LAQEGADIIAVDICKQI
TH_3237|M.thermoresistible__bu      ----MAGRLEGKVAFITGAARGQGRAHAVR---MAQEGADIIAVDICRQI
MSMEG_6031|M.smegmatis_MC2_155      ----MAGRVEGKVAFITGAARGQGRSHAVR---LAEEGADIIAVDVCRRI
MMAR_4754|M.marinum_M               MTEQLGGRVAGKVAFITGAARGQGRSHAVR---LAQEGADIIAVDVCKPI
MAV_0896|M.avium_104                ----MTGRVEGKVAFVTGAARGQGRSHAVR---LAQEGADIIAVDICKPI
MAB_0072c|M.abscessus_ATCC_199      ----MTGRLTGKVALVTGAARGIGRAQAVR---FAQEGADIIALDICAPV
MLBr_01807|M.leprae_Br4923          ---------MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRL
                                                .*  ..** * *:.  :    :.  *   *.: :.  :

Mb2771|M.bovis_AF2122/97            AS-----VPYPLSTADDLAATVELVEDAGGGIVARQGDVRDRASLSVALQ
Rv2750|M.tuberculosis_H37Rv         AS-----VPYPLSTADDLAATVELVEDAGGGIVARQGDVRDRASLSVALQ
MUL_3392|M.ulcerans_Agy99           AS-----VPYPLGTAEELATTVKLVEDTGARIVASQADVRDREALAAALQ
Mflv_2430|M.gilvum_PYR-GCK          DS-----VLIPLSTPEDLAETADLVKNAGGRIHTAEVDVRDYDALKAAVD
Mvan_4222|M.vanbaalenii_PYR-1       DS-----VLIPLSSPEDLAETADLVKNAGGRIHTAEVDVRDFDALKAAVD
TH_3237|M.thermoresistible__bu      DS-----VQIPLASPEDLAETADLVKGLNRRIYTAEVDVRDFDALKAAVD
MSMEG_6031|M.smegmatis_MC2_155      SS----NEDIPASTPEDLAETVELVKGLNRRIVAEEVDVRDYDALKAVVD
MMAR_4754|M.marinum_M               ---VEN-TTIPASTPEDLAETADLVKGHNRRIFTAEADVRDYDALKAAVD
MAV_0896|M.avium_104                RAGVVD-TAIPASTPEDLAETADLVKGHNRRIVTAEVDVRDYDALKAAVD
MAB_0072c|M.abscessus_ATCC_199      HT-----TITPPATRADLDKTSELVESAGRRVIPGVVDVRNLRDVQTFTQ
MLBr_01807|M.leprae_Br4923          VA------------DGHRVAVTHRASVVPDWFFGVECDVTDNDAIGAAFK
                                                    .   . . ..     .     ** :   : .  .

Mb2771|M.bovis_AF2122/97            AGLDEFGRLDIVVANAGIAMMQ-----AGDDGWRDVIDVNLTGVFHTVQV
Rv2750|M.tuberculosis_H37Rv         AGLDEFGRLDIVVANAGIAMMQ-----AGDDGWRDVIDVNLTGVFHTVQV
MUL_3392|M.ulcerans_Agy99           AGIDELGQVDIVVANAGIAPMQ-----SGDDGWRDVIDVNLSGAYYTVEV
Mflv_2430|M.gilvum_PYR-GCK          AGVEEFGRLDIIVANAGIGNGGQTLDKTDEPDWDDMIGVNLSGVWKTVKA
Mvan_4222|M.vanbaalenii_PYR-1       AGVEEFGRLDIIVANAGIGNGGQLLHDTGEPDWDDMIGVNLSGVWKTVKA
TH_3237|M.thermoresistible__bu      TGVEQLGRLDIIVANAGIGNGGETLDKTSEGDWTDMIDVNLAGVWKTVKA
MSMEG_6031|M.smegmatis_MC2_155      SGVEQLGGLDIVVANAGIGNGGATLDKTSEADWDDMIGVNLSGVWKTVKA
MMAR_4754|M.marinum_M               AGVDELGRLDIIVANAGIGNGGATLDKTSEHDWQEMIDVNLSGVWKSVKA
MAV_0896|M.avium_104                SGVEQLGRLDIIVANAGIGNGGDTLDKTSEEDWTEMIDINLAGVWKTVKA
MAB_0072c|M.abscessus_ATCC_199      DAVTEFGGLDIVCATAGITSRRMLLDMP-ESDWQTMLDVNLTGVWHTTRA
MLBr_01807|M.leprae_Br4923          AVEEHQGPVEVLVANAGITSDMLIMR-MSEEQFQKVIDVNLTGVFRVAKL
                                        . * :::: *.***           :  :  ::.:**:*.:  .. 

Mb2771|M.bovis_AF2122/97            AIPTLIEQGTGGSIVLISSAAGLVGIGSSDPGSLGYAAAKHGVVGLMRAY
Rv2750|M.tuberculosis_H37Rv         AIPTLIEQGTGGSIVLISSAAGLVGIGSSDPGSLGYAAAKHGVVGLMRAY
MUL_3392|M.ulcerans_Agy99           AIPTMIEQGRGGSIVLISSAAGLVGISSADAGAIGYVASKHALVGLMRVY
Mflv_2430|M.gilvum_PYR-GCK          GVPHILAGGNGGSIILTSSVGGLKAYPHTG----HYVAAKHGVVGLMRTF
Mvan_4222|M.vanbaalenii_PYR-1       GVPHILAGGNGGSIILTSSVGGLKAYPHTG----HYVAAKHGVVGLMRTF
TH_3237|M.thermoresistible__bu      GVPHILAGGRGGSIILTSSVGGLKAYPHTG----HYVAAKHGVVGLMRTF
MSMEG_6031|M.smegmatis_MC2_155      AVPHLISGGNGGSIILTSSVGGLKAYPHTG----HYIAAKHGVVGLMRTF
MMAR_4754|M.marinum_M               AVPHLIAGGNGGSIVLTSSVGGMKAYPHCG----NYVAAKHGVVGLMRSF
MAV_0896|M.avium_104                GVPHMIAGGRGGSIILTSSVGGLKAYPHTG----HYVAAKHGVVGLMRAF
MAB_0072c|M.abscessus_ATCC_199      ATPHLIARG-GGAMVLVSSIAGLRGLVGVS----HYVAAKHGVVGLMRSL
MLBr_01807|M.leprae_Br4923          ASRNMIKQRFGRYIFMG-SVVGLSGVPGQAN----YAASKSGLIGMARSL
                                    .   ::    *  :.:  *  *: .          * *:* .::*: *  

Mb2771|M.bovis_AF2122/97            ANHLAPQNIRVNSVHPCGVDTPMINNEFFQQWLT-------TADMDAPHN
Rv2750|M.tuberculosis_H37Rv         ANHLAPQNIRVNSVHPCGVDTPMINNEFFQQWLT-------TADMDAPHN
MUL_3392|M.ulcerans_Agy99           ANLLAPHSIRVNSLHPSGVDPPMINNEFIRHWLAD-----LVAETGSGPG
Mflv_2430|M.gilvum_PYR-GCK          AVELGAQNIRVNSVHPTNVNTPLFMNEPTMKLFRPDLENPGPDDMKVVGQ
Mvan_4222|M.vanbaalenii_PYR-1       AVELGAQNVRVNSVHPTNVNTPLFMNEPTMKLFRPDLENPGPEDMKVVGQ
TH_3237|M.thermoresistible__bu      AVELGQHNIRVNSVHPTNVNTPLFMNEPTMKLFRPDLENPGPEDLKVVAQ
MSMEG_6031|M.smegmatis_MC2_155      AVELGQHSIRVNSVHPTNVNTPLFMNEGTMKLFRPDLENPGPDDMAVVAQ
MMAR_4754|M.marinum_M               AVELGQHMIRVNSVHPTHVRTPMLHNEGTFKMFRPDLENPGPDDMAPICQ
MAV_0896|M.avium_104                GVELGQHMIRVNSVHPTHVKTPMLHNEGTFKMFRPDLENPGPDDMAPICQ
MAB_0072c|M.abscessus_ATCC_199      AIELAPHKIRVNTVHPTNVDTPMIQNEFVRTLFRPDLEQPTREDFAAAAK
MLBr_01807|M.leprae_Br4923          ARELGSRSITANVVAPGFIDTEMTR----------------AMDSKYQEA
                                    .  *. : : .* : *  : . :                    :      

Mb2771|M.bovis_AF2122/97            LGNALPVELVQP-TDIANAVAWLASEEARYVTGVTLPVDAGFVNKR
Rv2750|M.tuberculosis_H37Rv         LGNALPVELVQP-TDIANAVAWLASEEARYVTGVTLPVDAGFVNKR
MUL_3392|M.ulcerans_Agy99           AGNALPVQILQA-DDIAGALAWLVSDEARYITGVALPVDAGCVNKR
Mflv_2430|M.gilvum_PYR-GCK          LMHTLPIGWVEP-EDIANAVLFLASDEARFITGVTLPVDGGSCLK-
Mvan_4222|M.vanbaalenii_PYR-1       LMHTLPIGWVEP-EDIANAVLFLASDEARFITGVTLPVDGGSCLK-
TH_3237|M.thermoresistible__bu      MMHTLPIGWVEP-EDIANAVLFLASDEARYITGVTLPVDGGSCLK-
MSMEG_6031|M.smegmatis_MC2_155      MMHVLPVGWVEP-RDISNAVLFLASDEARYVTGLPMTVDAGSMLK-
MMAR_4754|M.marinum_M               LFHTLPIPWVEA-EDISNAVLFLASDESRYITGVTLPVDAGGCLK-
MAV_0896|M.avium_104                MFHTLPIPWVEP-IDISNAVLFFASDEARYITGVTLPIDAGSCLK-
MAB_0072c|M.abscessus_ATCC_199      TMNLLDLPWVEP-LDIANASLFLASDEARYITSVSLPVDAGSTQR-
MLBr_01807|M.leprae_Br4923          ALQAIPLGRIGAVEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH
                                      : : :  : .  :*:.*  ::.*::: :::.  :.:*.*