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M. thermoresistible (build 8) TH_3962 (-)

annotation: short-chain dehydrogenase/reductase SDR
coordinates: 803198 - 804040
length: 281

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3962--100% (281)short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_3237-3e-8153.99% (276) PUTATIVE short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_3018-7e-7549.82% (277) PUTATIVE carveol dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2771-1e-6551.47% (272) 3-ketoacyl-(acyl-carrier-protein) reductase
M. gilvum PYR-GCKMflv_2430-2e-8053.99% (276) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37RvRv2750-1e-6551.47% (272) 3-ketoacyl-(acyl-carrier-protein) reductase
M. leprae Br4923MLBr_01740-5e-2533.33% (234) short chain dehydrogenase
M. abscessus ATCC 19977MAB_0072c-2e-6850.00% (274) putative short chain dehydrogenase/reductase
M. marinum MMMAR_4754-1e-7652.71% (277) short-chain type dehydrogenase/reductase
M. avium 104MAV_1393-7e-7950.72% (276) carveol dehydrogenase
M. smegmatis MC2 155MSMEG_6031-6e-7854.87% (277) carveol dehydrogenase
M. ulcerans Agy99MUL_3392fabG3e-6448.91% (276) 3-ketoacyl-(acyl-carrier-protein) reductase
M. vanbaalenii PYR-1Mvan_4222-1e-7952.90% (276) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2430|M.gilvum_PYR-GCK          ----MAGRVEGKVAFITGAARGQGRAHAVRLAEEGADIIAVDICKQIDS-
Mvan_4222|M.vanbaalenii_PYR-1       ----MAGRVEGKVAFITGAARGQGRAHAVRLAQEGADIIAVDICKQIDS-
MSMEG_6031|M.smegmatis_MC2_155      ----MAGRVEGKVAFITGAARGQGRSHAVRLAEEGADIIAVDVCRRISSN
MMAR_4754|M.marinum_M               MTEQLGGRVAGKVAFITGAARGQGRSHAVRLAQEGADIIAVDVCKPIVEN
MAV_1393|M.avium_104                ----MAGKVEGKVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDG-
MAB_0072c|M.abscessus_ATCC_199      ----MTGRLTGKVALVTGAARGIGRAQAVRFAQEGADIIALDICAPVHT-
TH_3962|M.thermoresistible__bu      --LSIMGAFTGKVAFVTGAARGQGRSHALRLAREGAAIVALDIAADIDE-
Mb2771|M.bovis_AF2122/97            ---MIDRPLEGKVAFITGAARGLGRAHAVRLAADGANIIAVDICEQIAS-
Rv2750|M.tuberculosis_H37Rv         ---MIDRPLEGKVAFITGAARGLGRAHAVRLAADGANIIAVDICEQIAS-
MUL_3392|M.ulcerans_Agy99           MSRPLDGPLSGRVAFITGAARGQGRAHALRLARDGADVIAVDLCDQIAS-
MLBr_01740|M.leprae_Br4923          -MVKTAQYFVGKRCFVTGAASGIGRATALRLAAYGAELYLTDR-------
                                            . *: .::**** * **: *: :*  ** :   *        

Mflv_2430|M.gilvum_PYR-GCK          VLIPLSTPEDLAETADLVKNAGGRIHTA-EVDVRDYDALKAAVDAGVEEF
Mvan_4222|M.vanbaalenii_PYR-1       VLIPLSSPEDLAETADLVKNAGGRIHTA-EVDVRDFDALKAAVDAGVEEF
MSMEG_6031|M.smegmatis_MC2_155      EDIPASTPEDLAETVELVKGLNRRIVAE-EVDVRDYDALKAVVDSGVEQL
MMAR_4754|M.marinum_M               TTIPASTPEDLAETADLVKGHNRRIFTA-EADVRDYDALKAAVDAGVDEL
MAV_1393|M.avium_104                VKLPMSTPDDLAETVRQVEALGRRIIAS-QVDVRDFDAMQAAVDDGVTQL
MAB_0072c|M.abscessus_ATCC_199      TITPPATRADLDKTSELVESAGRRVIPG-VVDVRNLRDVQTFTQDAVTEF
TH_3962|M.thermoresistible__bu      CFFPLATPEDLQETVRLVEEDGGRILAR-RGDVRNYDDVKSAVDDGIAQF
Mb2771|M.bovis_AF2122/97            VPYPLSTADDLAATVELVEDAGGGIVAR-QGDVRDRASLSVALQAGLDEF
Rv2750|M.tuberculosis_H37Rv         VPYPLSTADDLAATVELVEDAGGGIVAR-QGDVRDRASLSVALQAGLDEF
MUL_3392|M.ulcerans_Agy99           VPYPLGTAEELATTVKLVEDTGARIVAS-QADVRDREALAAALQAGIDEL
MLBr_01740|M.leprae_Br4923          ------HCDGLAQTVSEARALGAQVPEYRALDISDYDEVAAFGADIHARH
                                              *  *   ..  .  :      *: :   :         . 

Mflv_2430|M.gilvum_PYR-GCK          GRLDIIVANAGIGNGGQTLDKTDEPDWDDMIGVNLSGVWKTVKAGVPHIL
Mvan_4222|M.vanbaalenii_PYR-1       GRLDIIVANAGIGNGGQLLHDTGEPDWDDMIGVNLSGVWKTVKAGVPHIL
MSMEG_6031|M.smegmatis_MC2_155      GGLDIVVANAGIGNGGATLDKTSEADWDDMIGVNLSGVWKTVKAAVPHLI
MMAR_4754|M.marinum_M               GRLDIIVANAGIGNGGATLDKTSEHDWQEMIDVNLSGVWKSVKAAVPHLI
MAV_1393|M.avium_104                GRLDIVLANAALASEGTRLNRMDPKTWRDMIDVNLNGAWITARVAIPHIM
MAB_0072c|M.abscessus_ATCC_199      GGLDIVCATAGITSRRMLLD-MPESDWQTMLDVNLTGVWHTTRAATPHLI
TH_3962|M.thermoresistible__bu      GPIGIVVANAGIGTAYKKTWEIPEADWRAALDVNLTGVFHTVKAAVPSMI
Mb2771|M.bovis_AF2122/97            GRLDIVVANAGIAMMQ-----AGDDGWRDVIDVNLTGVFHTVQVAIPTLI
Rv2750|M.tuberculosis_H37Rv         GRLDIVVANAGIAMMQ-----AGDDGWRDVIDVNLTGVFHTVQVAIPTLI
MUL_3392|M.ulcerans_Agy99           GQVDIVVANAGIAPMQ-----SGDDGWRDVIDVNLSGAYYTVEVAIPTMI
MLBr_01740|M.leprae_Br4923          PSMDIVMNIAGVSVWG-TVDRLTHDQWSNVVAINLMGPIHIIETFVPAIL
                                      :.*:   *.:              *   : :** *     ..  * ::

Mflv_2430|M.gilvum_PYR-GCK          AGGNGGSIILTSSVGGLKAYPHTG----HYVAAKHGVVGLMRTFAVELGA
Mvan_4222|M.vanbaalenii_PYR-1       AGGNGGSIILTSSVGGLKAYPHTG----HYVAAKHGVVGLMRTFAVELGA
MSMEG_6031|M.smegmatis_MC2_155      SGGNGGSIILTSSVGGLKAYPHTG----HYIAAKHGVVGLMRTFAVELGQ
MMAR_4754|M.marinum_M               AGGNGGSIVLTSSVGGMKAYPHCG----NYVAAKHGVVGLMRSFAVELGQ
MAV_1393|M.avium_104                AGKRGGSIVFTSSIGGLRGAENIG----NYIASKHGLHGLMRTMALELGP
MAB_0072c|M.abscessus_ATCC_199      ARG-GGAMVLVSSIAGLRGLVGVS----HYVAAKHGVVGLMRSLAIELAP
TH_3962|M.thermoresistible__bu      EAGRGGSITLISSSAGLKGYQHLA----PYVSSKHAVIGLMRTLANELAE
Mb2771|M.bovis_AF2122/97            EQGTGGSIVLISSAAGLVGIGSSDPGSLGYAAAKHGVVGLMRAYANHLAP
Rv2750|M.tuberculosis_H37Rv         EQGTGGSIVLISSAAGLVGIGSSDPGSLGYAAAKHGVVGLMRAYANHLAP
MUL_3392|M.ulcerans_Agy99           EQGRGGSIVLISSAAGLVGISSADAGAIGYVASKHALVGLMRVYANLLAP
MLBr_01740|M.leprae_Br4923          AAGRGGHLVNVSSAAGLVALPWHA----AYSASKYGLRGLSEVLRFDLAR
                                        ** :   ** .*: .          * ::*:.: ** .     *. 

Mflv_2430|M.gilvum_PYR-GCK          QNIRVNSVHPTNVNTPLFMNEPTMKLFRPDLENPGPDDMKVVGQLMHTLP
Mvan_4222|M.vanbaalenii_PYR-1       QNVRVNSVHPTNVNTPLFMNEPTMKLFRPDLENPGPEDMKVVGQLMHTLP
MSMEG_6031|M.smegmatis_MC2_155      HSIRVNSVHPTNVNTPLFMNEGTMKLFRPDLENPGPDDMAVVAQMMHVLP
MMAR_4754|M.marinum_M               HMIRVNSVHPTHVRTPMLHNEGTFKMFRPDLENPGPDDMAPICQLFHTLP
MAV_1393|M.avium_104                RNIRVNIVCPSSVATPMLLNEPTYRMFRPDLENPTVEDFKVASRQMHVLP
MAB_0072c|M.abscessus_ATCC_199      HKIRVNTVHPTNVDTPMIQNEFVRTLFRPDLEQPTREDFAAAAKTMNLLD
TH_3962|M.thermoresistible__bu      HNIRVNALCPGSVRTPMIINEPTFKVFRPDLDEPTEADAMEVFRQMPALP
Mb2771|M.bovis_AF2122/97            QNIRVNSVHPCGVDTPMINNEFFQQWLT-------TADMDAPHNLGNALP
Rv2750|M.tuberculosis_H37Rv         QNIRVNSVHPCGVDTPMINNEFFQQWLT-------TADMDAPHNLGNALP
MUL_3392|M.ulcerans_Agy99           HSIRVNSLHPSGVDPPMINNEFIRHWLAD-----LVAETGSGPGAGNALP
MLBr_01740|M.leprae_Br4923          YRIGVSVVVPGAVRTPLVDTIEIAGVDRQDPRFSRWVDRFRGHAVSAERA
                                      : *. : *  * .*:. .                 :            

Mflv_2430|M.gilvum_PYR-GCK          IGWVEPEDIANAVLFLASDEARFITGVT----------------------
Mvan_4222|M.vanbaalenii_PYR-1       IGWVEPEDIANAVLFLASDEARFITGVT----------------------
MSMEG_6031|M.smegmatis_MC2_155      VGWVEPRDISNAVLFLASDEARYVTGLP----------------------
MMAR_4754|M.marinum_M               IPWVEAEDISNAVLFLASDESRYITGVT----------------------
MAV_1393|M.avium_104                IPYVEPADISNAILFLVSDDARYITGVS----------------------
MAB_0072c|M.abscessus_ATCC_199      LPWVEPLDIANASLFLASDEARYITSVS----------------------
TH_3962|M.thermoresistible__bu      VDVLEPEDISEMVAFLASDAARYVTGLA----------------------
Mb2771|M.bovis_AF2122/97            VELVQPTDIANAVAWLASEEARYVTGVT----------------------
Rv2750|M.tuberculosis_H37Rv         VELVQPTDIANAVAWLASEEARYVTGVT----------------------
MUL_3392|M.ulcerans_Agy99           VQILQADDIAGALAWLVSDEARYITGVA----------------------
MLBr_01740|M.leprae_Br4923          AEKILAGVAKNRYLIYTSHDIRVLYGFKRLAWWPYGVVMKQVNVVFTRAL
                                       : .          .*.  * : ..                       

Mflv_2430|M.gilvum_PYR-GCK          ----------LPVDGGSCLK-----------
Mvan_4222|M.vanbaalenii_PYR-1       ----------LPVDGGSCLK-----------
MSMEG_6031|M.smegmatis_MC2_155      ----------MTVDAGSMLK-----------
MMAR_4754|M.marinum_M               ----------LPVDAGGCLK-----------
MAV_1393|M.avium_104                ----------LPVDGGALLK-----------
MAB_0072c|M.abscessus_ATCC_199      ----------LPVDAGSTQR-----------
TH_3962|M.thermoresistible__bu      ----------IPVDAGQLVK-----------
Mb2771|M.bovis_AF2122/97            ----------LPVDAGFVNKR----------
Rv2750|M.tuberculosis_H37Rv         ----------LPVDAGFVNKR----------
MUL_3392|M.ulcerans_Agy99           ----------LPVDAGCVNKR----------
MLBr_01740|M.leprae_Br4923          RPSPATMRCVEPIKVGVYSQPRSGEGGKSGN
                                               .:. *   :