For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_3018 (-)

annotation: carveol dehydrogenase
coordinates: 767783 - 768616
length: 278

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3018--100% (278)carveol dehydrogenase
M. thermoresistible (build 8)TH_3237-9e-8052.77% (271) PUTATIVE short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_3962-7e-7549.82% (277) PUTATIVE short-chain dehydrogenase/reductase SDR

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2771-7e-6546.89% (273) 3-ketoacyl-(acyl-carrier-protein) reductase
M. gilvum PYR-GCKMflv_2430-2e-7651.29% (271) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37RvRv2750-7e-6546.89% (273) 3-ketoacyl-(acyl-carrier-protein) reductase
M. leprae Br4923MLBr_01807fabG12e-2730.69% (277) 3-oxoacyl-
M. abscessus ATCC 19977MAB_3844c-3e-7350.74% (272) putative short-chain dehydrogenase/reductase
M. marinum MMMAR_4754-1e-7351.10% (272) short-chain type dehydrogenase/reductase
M. avium 104MAV_1393-2e-7650.18% (275) carveol dehydrogenase
M. smegmatis MC2 155MSMEG_6031-4e-7750.72% (276) carveol dehydrogenase
M. ulcerans Agy99MUL_3392fabG2e-6145.05% (273) 3-ketoacyl-(acyl-carrier-protein) reductase
M. vanbaalenii PYR-1Mvan_4222-2e-7651.66% (271) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


TH_3018|M.thermoresistible__bu      -----MNRLQGKVAFITGAARGQGRTHAVRLAQDGADIVAIDLCRQQPNL
MAB_3844c|M.abscessus_ATCC_199      ---MADQPLAGKVAFVTGAARGQGRQHAVRLAQAGADVVAIDACAPVSEY
Mb2771|M.bovis_AF2122/97            ---MIDRPLEGKVAFITGAARGLGRAHAVRLAADGANIIAVDICEQIAS-
Rv2750|M.tuberculosis_H37Rv         ---MIDRPLEGKVAFITGAARGLGRAHAVRLAADGANIIAVDICEQIAS-
MUL_3392|M.ulcerans_Agy99           MSRPLDGPLSGRVAFITGAARGQGRAHALRLARDGADVIAVDLCDQIAS-
Mflv_2430|M.gilvum_PYR-GCK          ----MAGRVEGKVAFITGAARGQGRAHAVRLAEEGADIIAVDICKQIDS-
Mvan_4222|M.vanbaalenii_PYR-1       ----MAGRVEGKVAFITGAARGQGRAHAVRLAQEGADIIAVDICKQIDS-
MSMEG_6031|M.smegmatis_MC2_155      ----MAGRVEGKVAFITGAARGQGRSHAVRLAEEGADIIAVDVCRRISSN
MMAR_4754|M.marinum_M               MTEQLGGRVAGKVAFITGAARGQGRSHAVRLAQEGADIIAVDVCKPIVEN
MAV_1393|M.avium_104                ----MAGKVEGKVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDG-
MLBr_01807|M.leprae_Br4923          ---------MTDAAAKVSAAPGRGK-----PAFVSRSILVTGGNRGIGLA
                                                .*  ..** * *:      *  . .::. .        

TH_3018|M.thermoresistible__bu      D-YAQGSPEELKETVRLVEEQGRRIIARQADVRDLASLQAVVDEALAEFG
MAB_3844c|M.abscessus_ATCC_199      AGYEAATPEDLKETVRLVEAAGRKIIAEQADVRNGAALQSVVEEAVAQFG
Mb2771|M.bovis_AF2122/97            VPYPLSTADDLAATVELVEDAGGGIVARQGDVRDRASLSVALQAGLDEFG
Rv2750|M.tuberculosis_H37Rv         VPYPLSTADDLAATVELVEDAGGGIVARQGDVRDRASLSVALQAGLDEFG
MUL_3392|M.ulcerans_Agy99           VPYPLGTAEELATTVKLVEDTGARIVASQADVRDREALAAALQAGIDELG
Mflv_2430|M.gilvum_PYR-GCK          VLIPLSTPEDLAETADLVKNAGGRIHTAEVDVRDYDALKAAVDAGVEEFG
Mvan_4222|M.vanbaalenii_PYR-1       VLIPLSSPEDLAETADLVKNAGGRIHTAEVDVRDFDALKAAVDAGVEEFG
MSMEG_6031|M.smegmatis_MC2_155      EDIPASTPEDLAETVELVKGLNRRIVAEEVDVRDYDALKAVVDSGVEQLG
MMAR_4754|M.marinum_M               TTIPASTPEDLAETADLVKGHNRRIFTAEADVRDYDALKAAVDAGVDELG
MAV_1393|M.avium_104                VKLPMSTPDDLAETVRQVEALGRRIIASQVDVRDFDAMQAAVDDGVTQLG
MLBr_01807|M.leprae_Br4923          VARRLVADGHRVAVTHRASVVPDWFFGVECDVTDNDAIGAAFKAVEEHQG
                                          :  .   ..  ..     :   : ** :  ::  ...    . *

TH_3018|M.thermoresistible__bu      HIDILVSNVGISNQG-EVVSLTDQQWSDILQTNLIGAWHACRAVLPSMIE
MAB_3844c|M.abscessus_ATCC_199      HIDILIANAGVLSWG-RLWEMSDQQWEDIIDTNLTGTWKTVKAVVPTMIE
Mb2771|M.bovis_AF2122/97            RLDIVVANAGIA-----MMQAGDDGWRDVIDVNLTGVFHTVQVAIPTLIE
Rv2750|M.tuberculosis_H37Rv         RLDIVVANAGIA-----MMQAGDDGWRDVIDVNLTGVFHTVQVAIPTLIE
MUL_3392|M.ulcerans_Agy99           QVDIVVANAGIA-----PMQSGDDGWRDVIDVNLSGAYYTVEVAIPTMIE
Mflv_2430|M.gilvum_PYR-GCK          RLDIIVANAGIGNGGQTLDKTDEPDWDDMIGVNLSGVWKTVKAGVPHILA
Mvan_4222|M.vanbaalenii_PYR-1       RLDIIVANAGIGNGGQLLHDTGEPDWDDMIGVNLSGVWKTVKAGVPHILA
MSMEG_6031|M.smegmatis_MC2_155      GLDIVVANAGIGNGGATLDKTSEADWDDMIGVNLSGVWKTVKAAVPHLIS
MMAR_4754|M.marinum_M               RLDIIVANAGIGNGGATLDKTSEHDWQEMIDVNLSGVWKSVKAAVPHLIA
MAV_1393|M.avium_104                RLDIVLANAALASEGTRLNRMDPKTWRDMIDVNLNGAWITARVAIPHIMA
MLBr_01807|M.leprae_Br4923          PVEVLVANAGITS-DMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIK
                                     ::::::*..:              : .:: .** *.:   .     :: 

TH_3018|M.thermoresistible__bu      RGQGGSVIFVSSTVGLRGAPGQS----HYAASKHGVQGLMLSLANEVGRH
MAB_3844c|M.abscessus_ATCC_199      AGNGGSIVIVSSVSGLKGTPGNG----AYVASKFGLTGLTKSLTIELAEY
Mb2771|M.bovis_AF2122/97            QGTGGSIVLISSAAGLVGIGSSDPGSLGYAAAKHGVVGLMRAYANHLAPQ
Rv2750|M.tuberculosis_H37Rv         QGTGGSIVLISSAAGLVGIGSSDPGSLGYAAAKHGVVGLMRAYANHLAPQ
MUL_3392|M.ulcerans_Agy99           QGRGGSIVLISSAAGLVGISSADAGAIGYVASKHALVGLMRVYANLLAPH
Mflv_2430|M.gilvum_PYR-GCK          GGNGGSIILTSSVGGLKAYPHTG----HYVAAKHGVVGLMRTFAVELGAQ
Mvan_4222|M.vanbaalenii_PYR-1       GGNGGSIILTSSVGGLKAYPHTG----HYVAAKHGVVGLMRTFAVELGAQ
MSMEG_6031|M.smegmatis_MC2_155      GGNGGSIILTSSVGGLKAYPHTG----HYIAAKHGVVGLMRTFAVELGQH
MMAR_4754|M.marinum_M               GGNGGSIVLTSSVGGMKAYPHCG----NYVAAKHGVVGLMRSFAVELGQH
MAV_1393|M.avium_104                GKRGGSIVFTSSIGGLRGAENIG----NYIASKHGLHGLMRTMALELGPR
MLBr_01807|M.leprae_Br4923          QRFG-RYIFMGSVVGLSGVPGQA----NYAASKSGLIGMARSLARELGSR
                                       *   :: .*  *: .          * *:* .: *:    :  :.  

TH_3018|M.thermoresistible__bu      NIRVNSVNPGAVNTEMA--LNEKLLKMFLPHLENPTREDAAELFSQLTLL
MAB_3844c|M.abscessus_ATCC_199      GIRVNSIHPYGVTTPMI--TGDAMMKILAEHPN------YLPSIAPMPLS
Mb2771|M.bovis_AF2122/97            NIRVNSVHPCGVDTPMI--NNE----FFQQWLT---TADMDAPHNLGNAL
Rv2750|M.tuberculosis_H37Rv         NIRVNSVHPCGVDTPMI--NNE----FFQQWLT---TADMDAPHNLGNAL
MUL_3392|M.ulcerans_Agy99           SIRVNSLHPSGVDPPMI--NNE----FIRHWLADL-VAETGSGPGAGNAL
Mflv_2430|M.gilvum_PYR-GCK          NIRVNSVHPTNVNTPLF--MNEPTMKLFRPDLENPGPDDMKVVGQLMHTL
Mvan_4222|M.vanbaalenii_PYR-1       NVRVNSVHPTNVNTPLF--MNEPTMKLFRPDLENPGPEDMKVVGQLMHTL
MSMEG_6031|M.smegmatis_MC2_155      SIRVNSVHPTNVNTPLF--MNEGTMKLFRPDLENPGPDDMAVVAQMMHVL
MMAR_4754|M.marinum_M               MIRVNSVHPTHVRTPML--HNEGTFKMFRPDLENPGPDDMAPICQLFHTL
MAV_1393|M.avium_104                NIRVNIVCPSSVATPML--LNEPTYRMFRPDLENPTVEDFKVASRQMHVL
MLBr_01807|M.leprae_Br4923          SITANVVAPGFIDTEMTRAM------------------DSKYQEAALQAI
                                     : .* : *  : . :                                  

TH_3018|M.thermoresistible__bu      PIPWV-EPEDVSNAVAWLASDEARYIHGAAIPVDGGQLARA
MAB_3844c|M.abscessus_ATCC_199      PTKML-EPDEISDVVLWLASDASGTLAGAQVPVDKGHLTY-
Mb2771|M.bovis_AF2122/97            PVELV-QPTDIANAVAWLASEEARYVTGVTLPVDAGFVNKR
Rv2750|M.tuberculosis_H37Rv         PVELV-QPTDIANAVAWLASEEARYVTGVTLPVDAGFVNKR
MUL_3392|M.ulcerans_Agy99           PVQIL-QADDIAGALAWLVSDEARYITGVALPVDAGCVNKR
Mflv_2430|M.gilvum_PYR-GCK          PIGWV-EPEDIANAVLFLASDEARFITGVTLPVDGGSCLK-
Mvan_4222|M.vanbaalenii_PYR-1       PIGWV-EPEDIANAVLFLASDEARFITGVTLPVDGGSCLK-
MSMEG_6031|M.smegmatis_MC2_155      PVGWV-EPRDISNAVLFLASDEARYVTGLPMTVDAGSMLK-
MMAR_4754|M.marinum_M               PIPWV-EAEDISNAVLFLASDESRYITGVTLPVDAGGCLK-
MAV_1393|M.avium_104                PIPYV-EPADISNAILFLVSDDARYITGVSLPVDGGALLK-
MLBr_01807|M.leprae_Br4923          PLGRIGAVEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH
                                    *   :    :::..: :*.*: :  : *  :.** *