For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TGRVEGKVAFVTGAARGQGRSHAVRLAQEGADIIAVDICKPIRAGVVDTAIPASTPEDLAETADLVKGHN RRIVTAEVDVRDYDALKAAVDSGVEQLGRLDIIVANAGIGNGGDTLDKTSEEDWTEMIDINLAGVWKTVK AGVPHMIAGGRGGSIILTSSVGGLKAYPHTGHYVAAKHGVVGLMRAFGVELGQHMIRVNSVHPTHVKTPM LHNEGTFKMFRPDLENPGPDDMAPICQMFHTLPIPWVEPIDISNAVLFFASDEARYITGVTLPIDAGSCL K*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0896 | - | - | 100% (282) | carveol dehydrogenase ((+)-trans-carveol dehydrogenase) |
| M. avium 104 | MAV_0846 | - | e-130 | 79.08% (282) | carveol dehydrogenase |
| M. avium 104 | MAV_2983 | - | e-122 | 75.18% (282) | carveol dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2771 | - | 4e-65 | 48.56% (278) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_2430 | - | 1e-127 | 79.08% (282) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2750 | - | 4e-65 | 48.56% (278) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01740 | - | 1e-22 | 33.17% (208) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0072c | - | 1e-79 | 53.41% (279) | putative short chain dehydrogenase/reductase |
| M. marinum M | MMAR_4754 | - | 1e-143 | 86.79% (280) | short-chain type dehydrogenase/reductase |
| M. smegmatis MC2 155 | MSMEG_4849 | - | 1e-145 | 88.30% (282) | carveol dehydrogenase |
| M. thermoresistible (build 8) | TH_3237 | - | 1e-133 | 81.56% (282) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_3392 | fabG | 6e-61 | 45.04% (282) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_5168 | - | 1e-125 | 75.89% (282) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2771|M.bovis_AF2122/97 ---MIDRPLEGKVAFITGAARGLGRAHAVRLAADGANIIAVDICEQIASV
Rv2750|M.tuberculosis_H37Rv ---MIDRPLEGKVAFITGAARGLGRAHAVRLAADGANIIAVDICEQIASV
MUL_3392|M.ulcerans_Agy99 MSRPLDGPLSGRVAFITGAARGQGRAHALRLARDGADVIAVDLCDQIASV
MAV_0896|M.avium_104 ----MTGRVEGKVAFVTGAARGQGRSHAVRLAQEGADIIAVDICKPIRAG
MSMEG_4849|M.smegmatis_MC2_155 ----MSGRVEGKVAFVTGAARGQGRSHALRLAQEGADIIAIDICGPIRPG
MMAR_4754|M.marinum_M MTEQLGGRVAGKVAFITGAARGQGRSHAVRLAQEGADIIAVDVCKPIVEN
Mflv_2430|M.gilvum_PYR-GCK ----MAGRVEGKVAFITGAARGQGRAHAVRLAEEGADIIAVDICKQIDSV
TH_3237|M.thermoresistible__bu ----MAGRLEGKVAFITGAARGQGRAHAVRMAQEGADIIAVDICRQIDSV
Mvan_5168|M.vanbaalenii_PYR-1 ----MGGRVEGKVAFITGAARGQGRSHAVRLAEEGADIIAIDVCGPISTH
MAB_0072c|M.abscessus_ATCC_199 ----MTGRLTGKVALVTGAARGIGRAQAVRFAQEGADIIALDICAPVHTT
MLBr_01740|M.leprae_Br4923 -MVKTAQYFVGKRCFVTGAASGIGRATALRLAAYGAELYLTDR-------
. *: .::**** * **: *:*:* **:: *
Mb2771|M.bovis_AF2122/97 ----PYPLSTADDLAATVELVEDAGGGIVAR-QGDVRDRASLSVALQAGL
Rv2750|M.tuberculosis_H37Rv ----PYPLSTADDLAATVELVEDAGGGIVAR-QGDVRDRASLSVALQAGL
MUL_3392|M.ulcerans_Agy99 ----PYPLGTAEELATTVKLVEDTGARIVAS-QADVRDREALAAALQAGI
MAV_0896|M.avium_104 VVDTAIPASTPEDLAETADLVKGHNRRIVTA-EVDVRDYDALKAAVDSGV
MSMEG_4849|M.smegmatis_MC2_155 -AETAIPASTSDDLAETANLVKGLDRRVVTA-EVDVRDAAAIKAAVDSGV
MMAR_4754|M.marinum_M ---TTIPASTPEDLAETADLVKGHNRRIFTA-EADVRDYDALKAAVDAGV
Mflv_2430|M.gilvum_PYR-GCK ----LIPLSTPEDLAETADLVKNAGGRIHTA-EVDVRDYDALKAAVDAGV
TH_3237|M.thermoresistible__bu ----QIPLASPEDLAETADLVKGLNRRIYTA-EVDVRDFDALKAAVDTGV
Mvan_5168|M.vanbaalenii_PYR-1 ---TDIPAATPDDLAQTVDLVKGIGRRVVAA-EVDVRDYAAVKAAVDSGV
MAB_0072c|M.abscessus_ATCC_199 ----ITPPATRADLDKTSELVESAGRRVIPG-VVDVRNLRDVQTFTQDAV
MLBr_01740|M.leprae_Br4923 ---------HCDGLAQTVSEARALGAQVPEYRALDISDYDEVAAFGADIH
* * . .. . : *: : : .
Mb2771|M.bovis_AF2122/97 DEFGRLDIVVANAGIAMMQ-----AGDDGWRDVIDVNLTGVFHTVQVAIP
Rv2750|M.tuberculosis_H37Rv DEFGRLDIVVANAGIAMMQ-----AGDDGWRDVIDVNLTGVFHTVQVAIP
MUL_3392|M.ulcerans_Agy99 DELGQVDIVVANAGIAPMQ-----SGDDGWRDVIDVNLSGAYYTVEVAIP
MAV_0896|M.avium_104 EQLGRLDIIVANAGIGNGGDTLDKTSEEDWTEMIDINLAGVWKTVKAGVP
MSMEG_4849|M.smegmatis_MC2_155 EQLGRLDIIVANAGIGNGGDTLDQTSEEDWDEMIDINLSGVWKSVKAGVP
MMAR_4754|M.marinum_M DELGRLDIIVANAGIGNGGATLDKTSEHDWQEMIDVNLSGVWKSVKAAVP
Mflv_2430|M.gilvum_PYR-GCK EEFGRLDIIVANAGIGNGGQTLDKTDEPDWDDMIGVNLSGVWKTVKAGVP
TH_3237|M.thermoresistible__bu EQLGRLDIIVANAGIGNGGETLDKTSEGDWTDMIDVNLAGVWKTVKAGVP
Mvan_5168|M.vanbaalenii_PYR-1 EQLGRLDIVVANAGIGNGGQTLDHTSEEDWNDMIDVNLSGVWKSVKAAVP
MAB_0072c|M.abscessus_ATCC_199 TEFGGLDIVCATAGITSRRMLLDMP-ESDWQTMLDVNLTGVWHTTRAATP
MLBr_01740|M.leprae_Br4923 ARHPSMDIVMNIAGVSVWG-TVDRLTHDQWSNVVAINLMGPIHIIETFVP
. :**: **: . * :: :** * .. *
Mb2771|M.bovis_AF2122/97 TLIEQGTGGSIVLISSAAGLVGIGSSDPGSLGYAAAKHGVVGLMRAYANH
Rv2750|M.tuberculosis_H37Rv TLIEQGTGGSIVLISSAAGLVGIGSSDPGSLGYAAAKHGVVGLMRAYANH
MUL_3392|M.ulcerans_Agy99 TMIEQGRGGSIVLISSAAGLVGISSADAGAIGYVASKHALVGLMRVYANL
MAV_0896|M.avium_104 HMIAGGRGGSIILTSSVGGLKAYPHTG----HYVAAKHGVVGLMRAFGVE
MSMEG_4849|M.smegmatis_MC2_155 HIVAGGRGGSIVLTSSVGGLKAYPHCG----NYVAAKHGVVGLMRGFAVE
MMAR_4754|M.marinum_M HLIAGGNGGSIVLTSSVGGMKAYPHCG----NYVAAKHGVVGLMRSFAVE
Mflv_2430|M.gilvum_PYR-GCK HILAGGNGGSIILTSSVGGLKAYPHTG----HYVAAKHGVVGLMRTFAVE
TH_3237|M.thermoresistible__bu HILAGGRGGSIILTSSVGGLKAYPHTG----HYVAAKHGVVGLMRTFAVE
Mvan_5168|M.vanbaalenii_PYR-1 HLLSGGRGGSIILTSSVGGLKPYAHTG----HYIAAKHGVIGLMRTFAVE
MAB_0072c|M.abscessus_ATCC_199 HLIARG-GGAMVLVSSIAGLRGLVGVS----HYVAAKHGVVGLMRSLAIE
MLBr_01740|M.leprae_Br4923 AILAAGRGGHLVNVSSAAGLVALPWHA----AYSASKYGLRGLSEVLRFD
:: * ** :: ** .*: * *:*:.: ** .
Mb2771|M.bovis_AF2122/97 LAPQNIRVNSVHPCGVDTPMINNEFFQQWLT-------TADMDAPHNLGN
Rv2750|M.tuberculosis_H37Rv LAPQNIRVNSVHPCGVDTPMINNEFFQQWLT-------TADMDAPHNLGN
MUL_3392|M.ulcerans_Agy99 LAPHSIRVNSLHPSGVDPPMINNEFIRHWLAD-----LVAETGSGPGAGN
MAV_0896|M.avium_104 LGQHMIRVNSVHPTHVKTPMLHNEGTFKMFRPDLENPGPDDMAPICQMFH
MSMEG_4849|M.smegmatis_MC2_155 LGQHNIRVNTVHPTHVATPMLHNEGTFKMFRPDLENPGPDDMAPICQMFH
MMAR_4754|M.marinum_M LGQHMIRVNSVHPTHVRTPMLHNEGTFKMFRPDLENPGPDDMAPICQLFH
Mflv_2430|M.gilvum_PYR-GCK LGAQNIRVNSVHPTNVNTPLFMNEPTMKLFRPDLENPGPDDMKVVGQLMH
TH_3237|M.thermoresistible__bu LGQHNIRVNSVHPTNVNTPLFMNEPTMKLFRPDLENPGPEDLKVVAQMMH
Mvan_5168|M.vanbaalenii_PYR-1 LGQHSIRVNAVCPTNVNTPLFMNEGTMKLFRPDLENPGPDDLAVAAQFMH
MAB_0072c|M.abscessus_ATCC_199 LAPHKIRVNTVHPTNVDTPMIQNEFVRTLFRPDLEQPTREDFAAAAKTMN
MLBr_01740|M.leprae_Br4923 LARYRIGVSVVVPGAVRTPLVDTIEIAGVDRQDPRFSRWVDRFRGHAVSA
*. * *. : * * .*:. . :
Mb2771|M.bovis_AF2122/97 ALPVELVQPTDIANAVAWLASEEARYVTGVT-------------------
Rv2750|M.tuberculosis_H37Rv ALPVELVQPTDIANAVAWLASEEARYVTGVT-------------------
MUL_3392|M.ulcerans_Agy99 ALPVQILQADDIAGALAWLVSDEARYITGVA-------------------
MAV_0896|M.avium_104 TLPIPWVEPIDISNAVLFFASDEARYITGVT-------------------
MSMEG_4849|M.smegmatis_MC2_155 TLPIPWVEPIDISNAVLFLASDEARYITGVT-------------------
MMAR_4754|M.marinum_M TLPIPWVEAEDISNAVLFLASDESRYITGVT-------------------
Mflv_2430|M.gilvum_PYR-GCK TLPIGWVEPEDIANAVLFLASDEARFITGVT-------------------
TH_3237|M.thermoresistible__bu TLPIGWVEPEDIANAVLFLASDEARYITGVT-------------------
Mvan_5168|M.vanbaalenii_PYR-1 VLPVGWVEPVDISNAVLFLASDEARYITGLP-------------------
MAB_0072c|M.abscessus_ATCC_199 LLDLPWVEPLDIANASLFLASDEARYITSVS-------------------
MLBr_01740|M.leprae_Br4923 ERAAEKILAGVAKNRYLIYTSHDIRVLYGFKRLAWWPYGVVMKQVNVVFT
: . . .*.: * : ..
Mb2771|M.bovis_AF2122/97 -------------LPVDAGFVNKR----------
Rv2750|M.tuberculosis_H37Rv -------------LPVDAGFVNKR----------
MUL_3392|M.ulcerans_Agy99 -------------LPVDAGCVNKR----------
MAV_0896|M.avium_104 -------------LPIDAGSCLK-----------
MSMEG_4849|M.smegmatis_MC2_155 -------------LPVDAGSCLK-----------
MMAR_4754|M.marinum_M -------------LPVDAGGCLK-----------
Mflv_2430|M.gilvum_PYR-GCK -------------LPVDGGSCLK-----------
TH_3237|M.thermoresistible__bu -------------LPVDGGSCLK-----------
Mvan_5168|M.vanbaalenii_PYR-1 -------------VTVDAGSMLK-----------
MAB_0072c|M.abscessus_ATCC_199 -------------LPVDAGSTQR-----------
MLBr_01740|M.leprae_Br4923 RALRPSPATMRCVEPIKVGVYSQPRSGEGGKSGN
.:. * :