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MSRPLDGPLSGRVAFITGAARGQGRAHALRLARDGADVIAVDLCDQIASVPYPLGTAEELATTVKLVEDT GARIVASQADVRDREALAAALQAGIDELGQVDIVVANAGIAPMQSGDDGWRDVIDVNLSGAYYTVEVAIP TMIEQGRGGSIVLISSAAGLVGISSADAGAIGYVASKHALVGLMRVYANLLAPHSIRVNSLHPSGVDPPM INNEFIRHWLADLVAETGSGPGAGNALPVQILQADDIAGALAWLVSDEARYITGVALPVDAGCVNKR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3392 | fabG | - | 100% (277) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. ulcerans Agy99 | MUL_0768 | - | 6e-44 | 38.19% (254) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. ulcerans Agy99 | MUL_0676 | - | 4e-39 | 35.94% (281) | carveol-like dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2771 | - | 1e-109 | 70.33% (273) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_3996 | - | 9e-94 | 61.11% (270) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. tuberculosis H37Rv | Rv2750 | - | 1e-109 | 70.33% (273) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 9e-24 | 30.45% (266) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_3081 | - | 4e-89 | 60.44% (273) | Short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_1965 | fabG | 1e-152 | 98.92% (277) | short chain dehydrogenase |
| M. avium 104 | MAV_3641 | - | 1e-116 | 72.83% (276) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. smegmatis MC2 155 | MSMEG_2687 | - | 1e-111 | 72.59% (270) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. thermoresistible (build 8) | TH_3053 | - | 1e-110 | 71.75% (269) | PUTATIVE carveol dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_2391 | - | 7e-97 | 63.97% (272) | 3-ketoacyl-(acyl-carrier-protein) reductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3996|M.gilvum_PYR-GCK MA--------------ELTGKVAFITGAARGQGRAHAVK---LASEGADI
Mvan_2391|M.vanbaalenii_PYR-1 MG--------------ELTGKVAFITGAARGQGRAHAVK---LASEGADI
MUL_3392|M.ulcerans_Agy99 MSRPLDGP---------LSGRVAFITGAARGQGRAHALR---LARDGADV
MMAR_1965|M.marinum_M MSRPLDGP---------LSGRVAFITGAARGQGRAHALR---LARDGADV
Mb2771|M.bovis_AF2122/97 ---MIDRP---------LEGKVAFITGAARGLGRAHAVR---LAADGANI
Rv2750|M.tuberculosis_H37Rv ---MIDRP---------LEGKVAFITGAARGLGRAHAVR---LAADGANI
MAV_3641|M.avium_104 MPRSSEGP---------LTGKVAFITGAARGQGRAHAVR---LAADGADI
MSMEG_2687|M.smegmatis_MC2_155 MSDTAP-----------LSGKVAFITGAARGQGRAEAVR---LAADGADI
TH_3053|M.thermoresistible__bu VADRQPGPDLPPGRSDSLRGRVAFITGAARGQGRAHAVR---LASEGADV
MAB_3081|M.abscessus_ATCC_1997 MG--------------KLDGKVAFITGAARGQGRAHAIK---LASEGASI
MLBr_01807|M.leprae_Br4923 ------------------MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRG
.* ..** * *:. : *. *
Mflv_3996|M.gilvum_PYR-GCK IALDLCAQIDSVPYPLATPDDMAATVKLVEEAGGRIATYEADVRDRDAVK
Mvan_2391|M.vanbaalenii_PYR-1 IALDLCAQIDSVPYPLATPEDLAATAKLVEDAGARIVTYQADVRDRDAVK
MUL_3392|M.ulcerans_Agy99 IAVDLCDQIASVPYPLGTAEELATTVKLVEDTGARIVASQADVRDREALA
MMAR_1965|M.marinum_M IAVDLCDQIASVPYPLGTAEELATTVKLVEDTGARIVASQADVRDREALA
Mb2771|M.bovis_AF2122/97 IAVDICEQIASVPYPLSTADDLAATVELVEDAGGGIVARQGDVRDRASLS
Rv2750|M.tuberculosis_H37Rv IAVDICEQIASVPYPLSTADDLAATVELVEDAGGGIVARQGDVRDRASLS
MAV_3641|M.avium_104 IAVDLCDQIASVPYPLATPEELAATVKLVEDIGSRIVARQADVRDRESLS
MSMEG_2687|M.smegmatis_MC2_155 IAVDLCAQIASVPYPLATPDDLATTAELVEKAGGRIVTRQADVRDEPELA
TH_3053|M.thermoresistible__bu IAVDLCDQIASVPYPLAGADDLAETARMVEEAGGRIVARQADVRDRDGLQ
MAB_3081|M.abscessus_ATCC_1997 IAVDICAQIPSVEYPMATTEDLDLTVKEVDALGRAISAHETDVRDREALQ
MLBr_01807|M.leprae_Br4923 IGLAVARRLVADGHRVAVTHRASVVP-------DWFFGVECDVTDNDAIG
*.: :. :: : : :. .. . : : ** *. :
Mflv_3996|M.gilvum_PYR-GCK AVVRDGTEKFGDRLDIVIANAGIA--PMA--A-ADAWQDVIDVNLTGVYN
Mvan_2391|M.vanbaalenii_PYR-1 AAVRDGTGKLGDRLDIVVANAGIA--PMA--S-ADAWQDVIDVNLTGVYN
MUL_3392|M.ulcerans_Agy99 AALQAGIDELG-QVDIVVANAGIA--PMQ--SGDDGWRDVIDVNLSGAYY
MMAR_1965|M.marinum_M AALQAGIDELG-QVDIVVANAGIA--PMQ--SGDDGWRDVIDVNLSGAYY
Mb2771|M.bovis_AF2122/97 VALQAGLDEFG-RLDIVVANAGIA--MMQ--AGDDGWRDVIDVNLTGVFH
Rv2750|M.tuberculosis_H37Rv VALQAGLDEFG-RLDIVVANAGIA--MMQ--AGDDGWRDVIDVNLTGVFH
MAV_3641|M.avium_104 AALQAGLDEFG-RLDIVVANAGIA--PMS--AGDDGWHDVIDVNLTGVYH
MSMEG_2687|M.smegmatis_MC2_155 AALAAGLDEFG-RLDIVVANAGIA--PML--SGPEGWRDVIDVNLTGVHH
TH_3053|M.thermoresistible__bu QALQAGLDELG-RLDIVIANAGIA--PLQ--SGPDGWRDVIDVNLTGVHH
MAB_3081|M.abscessus_ATCC_1997 AAFDAGVHDLG-PVDIVVANAGIA--TLTPECGDDGWRDVLDVNLTGVYH
MLBr_01807|M.leprae_Br4923 AAFKAVEEHQG-PVEVLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFR
.. . * :::::*****: : : ::.*:****:*..
Mflv_3996|M.gilvum_PYR-GCK TIDVAMKPMVKFGNGGAIVLTSSVAGLVGIGAPLGGSVGYAAAKHGIVGI
Mvan_2391|M.vanbaalenii_PYR-1 TVDVAMKPMVKFGNGGSIVLTSSVAGLIGLGAPIAGSVGYAAAKHGIVGI
MUL_3392|M.ulcerans_Agy99 TVEVAIPTMIEQGRGGSIVLISSAAGLVGISSADAGAIGYVASKHALVGL
MMAR_1965|M.marinum_M TVEVAIPTMIEQGRGGSIVLISSAAGLVGISSADAGAIGYAASKHALVGL
Mb2771|M.bovis_AF2122/97 TVQVAIPTLIEQGTGGSIVLISSAAGLVGIGSSDPGSLGYAAAKHGVVGL
Rv2750|M.tuberculosis_H37Rv TVQVAIPTLIEQGTGGSIVLISSAAGLVGIGSSDPGSLGYAAAKHGVVGL
MAV_3641|M.avium_104 TIKVAIPALVKQGTGGSIVLISSSAGLAGVGSADPGSVGYVAAKHGVVGL
MSMEG_2687|M.smegmatis_MC2_155 TVEVAIPTLVEQGDGGAIVLISSVAGLVGIGGGDRGSLGYTAAKHGIVGL
TH_3053|M.thermoresistible__bu TVEVAVPTLVEQGDGGSIVLISSVAGLVGMGGAKPGALGYTAAKHGIVGL
MAB_3081|M.abscessus_ATCC_1997 TIEVARPSMVQRGAGGSIVLTSSVAGLTGMVMDNPGGLAYTAAKHGLVGL
MLBr_01807|M.leprae_Br4923 VAKLASRNMIKQRFG-RYIFMGSVVGLSGVP----GQANYAASKSGLIGM
. .:* ::: * :: .* .** *: * *.*:* .::*:
Mflv_3996|M.gilvum_PYR-GCK MRVYANFLAQYSIRVNSVHPAGVNTPMIDNDFTRSWLDGMAQQSQGGPDM
Mvan_2391|M.vanbaalenii_PYR-1 MRVYANFLAQYSIRVNSVHPAAVNTPMIDNEFTRSWLDGMAQQSEGGPDM
MUL_3392|M.ulcerans_Agy99 MRVYANLLAPHSIRVNSLHPSGVDPPMINNEFIRHWLADLVAETGSGPGA
MMAR_1965|M.marinum_M MRVYANLLAPHSIRVNSLHPSGVDTPMINNEFIRRWLADLVAETGSGPGA
Mb2771|M.bovis_AF2122/97 MRAYANHLAPQNIRVNSVHPCGVDTPMINNEFFQQWLT--TADMDAPHNL
Rv2750|M.tuberculosis_H37Rv MRAYANHLAPQNIRVNSVHPCGVDTPMINNEFFQQWLT--TADMDAPHNL
MAV_3641|M.avium_104 MRVYANLLAGQMIRVNSIHPSGVETPMINNEFTREWLAKMAAATDTPGAM
MSMEG_2687|M.smegmatis_MC2_155 MRAYANHLAPHSIRVNSVHPTGVDTPMIDNEFTRGWLAHITEETGRPVDM
TH_3053|M.thermoresistible__bu MRQYANLLAPHHIRVNSVHPTGVDTPMIDNEFTRQFLQQVLAEAQRPMDM
MAB_3081|M.abscessus_ATCC_1997 MRSYANMLAPHNIRVNTIHPSGVATPMLINPVTEKLFADGSPEGMS--DT
MLBr_01807|M.leprae_Br4923 ARSLARELGSRSITANVVAPG-----FIDTEMTRAMDSKYQEAALQAIPL
* *. *. * .* : * :: . . .
Mflv_3996|M.gilvum_PYR-GCK GNALPVQTLEPEDIANAVYWLVSDAARYVTGITLPVDAGFVNKR
Mvan_2391|M.vanbaalenii_PYR-1 GNALPVSALEPEDIANAVFWLVSDAARYVTGITLPVDAGYINKR
MUL_3392|M.ulcerans_Agy99 GNALPVQILQADDIAGALAWLVSDEARYITGVALPVDAGCVNKR
MMAR_1965|M.marinum_M GNALPVQILQADDIAGALAWLVSDEARYITGVALPVDAGCVNKR
Mb2771|M.bovis_AF2122/97 GNALPVELVQPTDIANAVAWLASEEARYVTGVTLPVDAGFVNKR
Rv2750|M.tuberculosis_H37Rv GNALPVELVQPTDIANAVAWLASEEARYVTGVTLPVDAGFVNKR
MAV_3641|M.avium_104 GNAMPVEVLAPEDVANAVAWLVSDQARYITGVTLPVDAGFLNK-
MSMEG_2687|M.smegmatis_MC2_155 GNALPVQAIDADDVANAVAWLVSDQARYVTGVTLPVDAGIVNKR
TH_3053|M.thermoresistible__bu GNALPVQAIEPEDVANAVAWLVSDAARYVTGVALPVDAGSVNKR
MAB_3081|M.abscessus_ATCC_1997 GNALPVVLMEPEDMANTVAWLVSEDARYITGVALPVDAGFTNRR
MLBr_01807|M.leprae_Br4923 GRIG-----AVEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH
*. ::*.:: :*.*: * *::* .:***.*