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MTEQLGGRVAGKVAFITGAARGQGRSHAVRLAQEGADIIAVDVCKPIVENTTIPASTPEDLAETADLVKG HNRRIFTAEADVRDYDALKAAVDAGVDELGRLDIIVANAGIGNGGATLDKTSEHDWQEMIDVNLSGVWKS VKAAVPHLIAGGNGGSIVLTSSVGGMKAYPHCGNYVAAKHGVVGLMRSFAVELGQHMIRVNSVHPTHVRT PMLHNEGTFKMFRPDLENPGPDDMAPICQLFHTLPIPWVEAEDISNAVLFLASDESRYITGVTLPVDAGG CLK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4754 | - | - | 100% (283) | short-chain type dehydrogenase/reductase |
| M. marinum M | MMAR_1965 | fabG | 8e-65 | 48.06% (283) | short chain dehydrogenase |
| M. marinum M | MMAR_1016 | - | 2e-64 | 46.01% (276) | short-chain dehydrogenase/reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2771 | - | 2e-65 | 50.55% (273) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_2430 | - | 1e-125 | 78.85% (279) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2750 | - | 2e-65 | 50.55% (273) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 4e-24 | 32.25% (276) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0072c | - | 1e-77 | 54.95% (273) | putative short chain dehydrogenase/reductase |
| M. avium 104 | MAV_0896 | - | 1e-143 | 86.79% (280) | carveol dehydrogenase ((+)-trans-carveol dehydrogenase) |
| M. smegmatis MC2 155 | MSMEG_4849 | - | 1e-136 | 83.27% (281) | carveol dehydrogenase |
| M. thermoresistible (build 8) | TH_3237 | - | 1e-127 | 77.78% (279) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_3392 | fabG | 2e-64 | 48.06% (283) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_5168 | - | 1e-122 | 74.91% (279) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2771|M.bovis_AF2122/97 ---MIDRPLEGKVAFITGAARGLGRAHAVR---LAADGANIIAVDICEQI
Rv2750|M.tuberculosis_H37Rv ---MIDRPLEGKVAFITGAARGLGRAHAVR---LAADGANIIAVDICEQI
MUL_3392|M.ulcerans_Agy99 MSRPLDGPLSGRVAFITGAARGQGRAHALR---LARDGADVIAVDLCDQI
MAV_0896|M.avium_104 ----MTGRVEGKVAFVTGAARGQGRSHAVR---LAQEGADIIAVDICKPI
MSMEG_4849|M.smegmatis_MC2_155 ----MSGRVEGKVAFVTGAARGQGRSHALR---LAQEGADIIAIDICGPI
MMAR_4754|M.marinum_M MTEQLGGRVAGKVAFITGAARGQGRSHAVR---LAQEGADIIAVDVCKPI
Mflv_2430|M.gilvum_PYR-GCK ----MAGRVEGKVAFITGAARGQGRAHAVR---LAEEGADIIAVDICKQI
TH_3237|M.thermoresistible__bu ----MAGRLEGKVAFITGAARGQGRAHAVR---MAQEGADIIAVDICRQI
Mvan_5168|M.vanbaalenii_PYR-1 ----MGGRVEGKVAFITGAARGQGRSHAVR---LAEEGADIIAIDVCGPI
MAB_0072c|M.abscessus_ATCC_199 ----MTGRLTGKVALVTGAARGIGRAQAVR---FAQEGADIIALDICAPV
MLBr_01807|M.leprae_Br4923 ---------MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRL
.* ..** * *:. : :. * *.: :. :
Mb2771|M.bovis_AF2122/97 ASV----PYPLSTADDLAATVELVEDAGGGIVARQGDVRDRASLSVALQA
Rv2750|M.tuberculosis_H37Rv ASV----PYPLSTADDLAATVELVEDAGGGIVARQGDVRDRASLSVALQA
MUL_3392|M.ulcerans_Agy99 ASV----PYPLGTAEELATTVKLVEDTGARIVASQADVRDREALAAALQA
MAV_0896|M.avium_104 RAGVVDTAIPASTPEDLAETADLVKGHNRRIVTAEVDVRDYDALKAAVDS
MSMEG_4849|M.smegmatis_MC2_155 RPG-AETAIPASTSDDLAETANLVKGLDRRVVTAEVDVRDAAAIKAAVDS
MMAR_4754|M.marinum_M VEN---TTIPASTPEDLAETADLVKGHNRRIFTAEADVRDYDALKAAVDA
Mflv_2430|M.gilvum_PYR-GCK DSV----LIPLSTPEDLAETADLVKNAGGRIHTAEVDVRDYDALKAAVDA
TH_3237|M.thermoresistible__bu DSV----QIPLASPEDLAETADLVKGLNRRIYTAEVDVRDFDALKAAVDT
Mvan_5168|M.vanbaalenii_PYR-1 STH---TDIPAATPDDLAQTVDLVKGIGRRVVAAEVDVRDYAAVKAAVDS
MAB_0072c|M.abscessus_ATCC_199 HTT----ITPPATRADLDKTSELVESAGRRVIPGVVDVRNLRDVQTFTQD
MLBr_01807|M.leprae_Br4923 VAD--------GHRVAVTHRASVVP---DWFFGVECDVTDNDAIGAAFKA
. : .:* . ** : : . .
Mb2771|M.bovis_AF2122/97 GLDEFGRLDIVVANAGIAMMQ-----AGDDGWRDVIDVNLTGVFHTVQVA
Rv2750|M.tuberculosis_H37Rv GLDEFGRLDIVVANAGIAMMQ-----AGDDGWRDVIDVNLTGVFHTVQVA
MUL_3392|M.ulcerans_Agy99 GIDELGQVDIVVANAGIAPMQ-----SGDDGWRDVIDVNLSGAYYTVEVA
MAV_0896|M.avium_104 GVEQLGRLDIIVANAGIGNGGDTLDKTSEEDWTEMIDINLAGVWKTVKAG
MSMEG_4849|M.smegmatis_MC2_155 GVEQLGRLDIIVANAGIGNGGDTLDQTSEEDWDEMIDINLSGVWKSVKAG
MMAR_4754|M.marinum_M GVDELGRLDIIVANAGIGNGGATLDKTSEHDWQEMIDVNLSGVWKSVKAA
Mflv_2430|M.gilvum_PYR-GCK GVEEFGRLDIIVANAGIGNGGQTLDKTDEPDWDDMIGVNLSGVWKTVKAG
TH_3237|M.thermoresistible__bu GVEQLGRLDIIVANAGIGNGGETLDKTSEGDWTDMIDVNLAGVWKTVKAG
Mvan_5168|M.vanbaalenii_PYR-1 GVEQLGRLDIVVANAGIGNGGQTLDHTSEEDWNDMIDVNLSGVWKSVKAA
MAB_0072c|M.abscessus_ATCC_199 AVTEFGGLDIVCATAGITSRRMLLDMP-ESDWQTMLDVNLTGVWHTTRAA
MLBr_01807|M.leprae_Br4923 VEEHQGPVEVLVANAGITSDMLIMR-MSEEQFQKVIDVNLTGVFRVAKLA
. * :::: *.*** : : ::.:**:*.: .. .
Mb2771|M.bovis_AF2122/97 IPTLIEQGTGGSIVLISSAAGLVGIGSSDPGSLGYAAAKHGVVGLMRAYA
Rv2750|M.tuberculosis_H37Rv IPTLIEQGTGGSIVLISSAAGLVGIGSSDPGSLGYAAAKHGVVGLMRAYA
MUL_3392|M.ulcerans_Agy99 IPTMIEQGRGGSIVLISSAAGLVGISSADAGAIGYVASKHALVGLMRVYA
MAV_0896|M.avium_104 VPHMIAGGRGGSIILTSSVGGLKAYPHTG----HYVAAKHGVVGLMRAFG
MSMEG_4849|M.smegmatis_MC2_155 VPHIVAGGRGGSIVLTSSVGGLKAYPHCG----NYVAAKHGVVGLMRGFA
MMAR_4754|M.marinum_M VPHLIAGGNGGSIVLTSSVGGMKAYPHCG----NYVAAKHGVVGLMRSFA
Mflv_2430|M.gilvum_PYR-GCK VPHILAGGNGGSIILTSSVGGLKAYPHTG----HYVAAKHGVVGLMRTFA
TH_3237|M.thermoresistible__bu VPHILAGGRGGSIILTSSVGGLKAYPHTG----HYVAAKHGVVGLMRTFA
Mvan_5168|M.vanbaalenii_PYR-1 VPHLLSGGRGGSIILTSSVGGLKPYAHTG----HYIAAKHGVIGLMRTFA
MAB_0072c|M.abscessus_ATCC_199 TPHLIARG-GGAMVLVSSIAGLRGLVGVS----HYVAAKHGVVGLMRSLA
MLBr_01807|M.leprae_Br4923 SRNMIKQRFGRYIFMG-SVVGLSGVPGQA----NYAASKSGLIGMARSLA
:: * :.: * *: * *:* .::*: * .
Mb2771|M.bovis_AF2122/97 NHLAPQNIRVNSVHPCGVDTPMINNEFFQQWLT-------TADMDAPHNL
Rv2750|M.tuberculosis_H37Rv NHLAPQNIRVNSVHPCGVDTPMINNEFFQQWLT-------TADMDAPHNL
MUL_3392|M.ulcerans_Agy99 NLLAPHSIRVNSLHPSGVDPPMINNEFIRHWLAD-----LVAETGSGPGA
MAV_0896|M.avium_104 VELGQHMIRVNSVHPTHVKTPMLHNEGTFKMFRPDLENPGPDDMAPICQM
MSMEG_4849|M.smegmatis_MC2_155 VELGQHNIRVNTVHPTHVATPMLHNEGTFKMFRPDLENPGPDDMAPICQM
MMAR_4754|M.marinum_M VELGQHMIRVNSVHPTHVRTPMLHNEGTFKMFRPDLENPGPDDMAPICQL
Mflv_2430|M.gilvum_PYR-GCK VELGAQNIRVNSVHPTNVNTPLFMNEPTMKLFRPDLENPGPDDMKVVGQL
TH_3237|M.thermoresistible__bu VELGQHNIRVNSVHPTNVNTPLFMNEPTMKLFRPDLENPGPEDLKVVAQM
Mvan_5168|M.vanbaalenii_PYR-1 VELGQHSIRVNAVCPTNVNTPLFMNEGTMKLFRPDLENPGPDDLAVAAQF
MAB_0072c|M.abscessus_ATCC_199 IELAPHKIRVNTVHPTNVDTPMIQNEFVRTLFRPDLEQPTREDFAAAAKT
MLBr_01807|M.leprae_Br4923 RELGSRSITANVVAPGFIDTEMTR----------------AMDSKYQEAA
*. : * .* : * : . : :
Mb2771|M.bovis_AF2122/97 GNALPVELV-QPTDIANAVAWLASEEARYVTGVTLPVDAGFVNKR
Rv2750|M.tuberculosis_H37Rv GNALPVELV-QPTDIANAVAWLASEEARYVTGVTLPVDAGFVNKR
MUL_3392|M.ulcerans_Agy99 GNALPVQIL-QADDIAGALAWLVSDEARYITGVALPVDAGCVNKR
MAV_0896|M.avium_104 FHTLPIPWV-EPIDISNAVLFFASDEARYITGVTLPIDAGSCLK-
MSMEG_4849|M.smegmatis_MC2_155 FHTLPIPWV-EPIDISNAVLFLASDEARYITGVTLPVDAGSCLK-
MMAR_4754|M.marinum_M FHTLPIPWV-EAEDISNAVLFLASDESRYITGVTLPVDAGGCLK-
Mflv_2430|M.gilvum_PYR-GCK MHTLPIGWV-EPEDIANAVLFLASDEARFITGVTLPVDGGSCLK-
TH_3237|M.thermoresistible__bu MHTLPIGWV-EPEDIANAVLFLASDEARYITGVTLPVDGGSCLK-
Mvan_5168|M.vanbaalenii_PYR-1 MHVLPVGWV-EPVDISNAVLFLASDEARYITGLPVTVDAGSMLK-
MAB_0072c|M.abscessus_ATCC_199 MNLLDLPWV-EPLDIANASLFLASDEARYITSVSLPVDAGSTQR-
MLBr_01807|M.leprae_Br4923 LQAIPLGRIGAVEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH
: : : : :*:.* ::.*::: :::. :.:*.*