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M. thermoresistible (build 8) TH_2894 (-)

annotation: transcriptional regulator, TetR family
coordinates: 4150761 - 4151375
length: 205

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2894--100% (205)transcriptional regulator, TetR family
M. thermoresistible (build 8)TH_3734-1e-2535.38% (195) PUTATIVE putative transcriptional regulator, TetR family
M. thermoresistible (build 8)TH_4497-3e-2536.13% (191) PUTATIVE putative transcriptional regulator, TetR family

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0080-6e-0626.74% (172) transcriptional regulatory protein
M. gilvum PYR-GCKMflv_2097-9e-5254.10% (183) TetR family transcriptional regulator
M. tuberculosis H37RvRv0078-8e-0626.74% (172) transcriptional regulatory protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2061c-1e-0627.75% (191) TetR family transcriptional regulator
M. marinum MMMAR_1569-4e-1633.33% (189) putative regulatory protein
M. avium 104MAV_2439-5e-1833.33% (189) transcriptional regulator, TetR family protein, putative
M. smegmatis MC2 155MSMEG_2193-6e-0726.14% (176) transcriptional regulator, TetR family protein
M. ulcerans Agy99MUL_3464-6e-1633.33% (189) putative regulatory protein
M. vanbaalenii PYR-1Mvan_4608-1e-5152.66% (188) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb0080|M.bovis_AF2122/97            ------------------------------------------MEIKRRTQ
Rv0078|M.tuberculosis_H37Rv         ------------------------------------------MEIKRRTQ
Mflv_2097|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4608|M.vanbaalenii_PYR-1       -----------------------------------------------MQP
TH_2894|M.thermoresistible__bu      -----------------------------------------------VAT
MMAR_1569|M.marinum_M               MSDIAATMKCRLRVSRKRLVGTYGSMTHPNNPGTRRQADLSSRLTRRRHK
MUL_3464|M.ulcerans_Agy99           MSDIAATMKCRLRVSRKRLVGTYGSMTHPNNPGTRRQADLSSRLTRRRHK
MAV_2439|M.avium_104                --------------------------------------------------
MAB_2061c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_2193|M.smegmatis_MC2_155      -----------------------------------------------MAR
                                                                                      

Mb0080|M.bovis_AF2122/97            EERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADK
Rv0078|M.tuberculosis_H37Rv         EERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADK
Mflv_2097|M.gilvum_PYR-GCK          -----------MEAAYRCLADPHAGPVSMAAILGTAGVSSRAFYRHFESK
Mvan_4608|M.vanbaalenii_PYR-1       GPDHDGDRRRIIEAAYRCLAQPHAGPIPMTSILRSAGLSSRAFYRHFLSK
TH_2894|M.thermoresistible__bu      DSPASEDRKRIIDAAYQCLSERHVNPVSVAAILARAECSSRAFYRHFESK
MMAR_1569|M.marinum_M               LAPDPGIRRAILVAASMSVREHGVRGLSVATVLDRAQLSTRAFYRHFESK
MUL_3464|M.ulcerans_Agy99           LAPDPGIRRAILVAASMSVREHGVRGLSVATVLDRAQLSTRAFYRHFESK
MAV_2439|M.avium_104                ------MRRAILDAASTTLRRQGVDGLSIAAVLSRASLSTRAFYRHFGSK
MAB_2061c|M.abscessus_ATCC_199      --MAGLRRKLLLEAAADLFARQGFHAVGIDDIGAAAGVSGPAVYRHFQNK
MSMEG_2193|M.smegmatis_MC2_155      QARAGVTRRKIITAAVDLFAEIGYPATGLGEIIERADMTKGALYYHFDSK
                                               : .*                :   *  :  *.* :* .*

Mb0080|M.bovis_AF2122/97            AALFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPE
Rv0078|M.tuberculosis_H37Rv         AALFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPE
Mflv_2097|M.gilvum_PYR-GCK          DDLFLALLEQECSAVVGQVDRVADAAQGS-PADQLAAWIEAMFDIVVDPR
Mvan_4608|M.vanbaalenii_PYR-1       DDLFLALLRQECEAVIAQVDRIADAAVGS-PADQLADWIAAMFDIIVDPQ
TH_2894|M.thermoresistible__bu      DALFLAMVEEESAALTRRLDRIVAEHPGT-PIEQLQAWVEQLFALVYDPA
MMAR_1569|M.marinum_M               DQLVAAVFLEVARVEAVRLRTLMAKATN--PIEGVAAWIDGRLDLAFDDA
MUL_3464|M.ulcerans_Agy99           DQLVAAMFLEVARVEAVRLRTLMAKATN--PIEGVAAWIDGRLDLAFDDA
MAV_2439|M.avium_104                DELVAAVFLEHARAEKRRLRRRMTGAAS--EAEAVAAWIDGRLDLAFDDR
MAB_2061c|M.abscessus_ATCC_199      DAILRELCDAAMTELLAGARRATTAGTP---TEVLHALVD--LHAAFGAR
MSMEG_2193|M.smegmatis_MC2_155      EALAEAIIAESGASMLAAFQNITETSSP-----ALENLIHG-LFVVCDFT
                                      :   :                           :   :   :    .  

Mb0080|M.bovis_AF2122/97            VR-QLVLLDAPVVLGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQ--P
Rv0078|M.tuberculosis_H37Rv         VR-QLILLDAPVVLGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQ--P
Mflv_2097|M.gilvum_PYR-GCK          QRLQLTVIDSEEVRTAKGYRQTRDRLHAARERGLAEILRRGLRDGSF--P
Mvan_4608|M.vanbaalenii_PYR-1       QRLQLTVIDSDEVRAAKGYREMRERLHAERERSLAEILRRGRRDGSF--P
TH_2894|M.thermoresistible__bu      LREHMQVIDSDEVRSAKGFREVRERAHIERERSLRTILTRGRADGSM--P
MMAR_1569|M.marinum_M               VKADLRHLSMDAQSHLLNTPELVEPAYAETLEPLIEQLHLGVAQEVF--H
MUL_3464|M.ulcerans_Agy99           VKADLRHLSMGAQSHLLNAPELVEPAYAETLEPLIEQLHLGVAQEVF--H
MAV_2439|M.avium_104                IGNDLRRLSLEAQSQAMGPAELIQPAYAEMLEPLRDALQRGSQNGVF--H
MAB_2061c|M.abscessus_ATCC_199      RRGLLAVYAREHRSLSPLATRALRRRQHSYESFWVEALVRARGDLDR--E
MSMEG_2193|M.smegmatis_MC2_155      RTDRVADIGLHLLQTFAGINDTTARVYASWLDAISAQLHRAAAEGDLREG
                                        :                                   .         

Mb0080|M.bovis_AF2122/97            VRP--LAQVLIGALDEAAMFIATADDPKRARRETRQVLRRLIDGMLNG--
Rv0078|M.tuberculosis_H37Rv         VRP--LAQVLIGALDEAAMFIATADDPKRARRETRQVLRRLIDGMLNG--
Mflv_2097|M.gilvum_PYR-GCK          LTEPEADAVAINAVVSRVLNTQTTDEPEARKKALVAVLDFALRAVGAAAR
Mvan_4608|M.vanbaalenii_PYR-1       LAEPEIDAVAVNALVSRLLVRQTTDDPQARKQAEVAVLDFALRAVGAVPG
TH_2894|M.thermoresistible__bu      LTDPECDAVAIGAVVARALLEQTDLTDDEYRVGVECVMDFALRAIGADHT
MMAR_1569|M.marinum_M               DVDPHSEARSIQGVVWANTEQQWASGDCRRDEVRESTVRFCLRGLGVAPD
MUL_3464|M.ulcerans_Agy99           DVDPHSEARSIQGVVWANTEQQWASGDCRRDEVRESTVRFCLRGLGVAPD
MAV_2439|M.avium_104                DVDPVTQAQFIHGVVWTGIARQWASGDCDRDDLRRRVQRFCLRGLGIADE
MAB_2061c|M.abscessus_ATCC_199      RAQGLVAAVLSLLNASAYMPASLDDATIEAMLAAAAVAALFSRAVTQQVD
MSMEG_2193|M.smegmatis_MC2_155      LDPGAVADVVLSALLGAEALTRAGTSGTDLRERLVRTWDLLLPALVEPAS
                                                                        .      .:     

Mb0080|M.bovis_AF2122/97            --------------------
Rv0078|M.tuberculosis_H37Rv         --------------------
Mflv_2097|M.gilvum_PYR-GCK          --------------------
Mvan_4608|M.vanbaalenii_PYR-1       GQDTRR--------------
TH_2894|M.thermoresistible__bu      PYRR----------------
MMAR_1569|M.marinum_M               TIAQITAPD-----------
MUL_3464|M.ulcerans_Agy99           TIAQITAPD-----------
MAV_2439|M.avium_104                VIDRVCFVMERG--------
MAB_2061c|M.abscessus_ATCC_199      GAPHRI--------------
MSMEG_2193|M.smegmatis_MC2_155      LDYFREFLARESMRRSPGTD