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MEIKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALFRDVVEVVE QDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVVLGWAGFRDVAQRYSLGMTEQ LITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDPKRARRETRQVLRRLIDGMLNG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0078 | - | - | 100% (201) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. tuberculosis H37Rv | Rv1534 | - | 1e-08 | 23.00% (200) | transcriptional regulator |
| M. tuberculosis H37Rv | Rv3295 | - | 2e-07 | 38.78% (98) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0080 | - | 1e-109 | 99.50% (201) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3666 | - | 4e-09 | 28.49% (179) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02677 | - | 7e-62 | 71.43% (175) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4352c | - | 7e-21 | 30.10% (196) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0224 | - | 1e-100 | 93.50% (200) | transcriptional regulatory protein |
| M. avium 104 | MAV_5253 | - | 2e-93 | 86.50% (200) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1565 | - | 2e-08 | 26.14% (176) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3094 | - | 2e-32 | 38.10% (189) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_4890 | - | 3e-98 | 91.50% (200) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_2744 | - | 6e-10 | 28.65% (178) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0078|M.tuberculosis_H37Rv --MEIKRRTQEER-----SAATREALITGARKLWGLRGYAEVGTPEIATE
Mb0080|M.bovis_AF2122/97 --MEIKRRTQEER-----SAATREALITGARKLWGLRGYAEVGTPEIATE
MMAR_0224|M.marinum_M --MEIKRRTQEER-----SAATREALITAARKLWGSRGYAEVGTPEIAAE
MUL_4890|M.ulcerans_Agy99 --MESKRRTQEER-----SAATREALITAARKLWGSRGYAEVGTPEIAAE
MAV_5253|M.avium_104 --MESKRRTQEER-----SAATRDALIAAARKLWGLRGYTEVGTPEIAAA
MLBr_02677|M.leprae_Br4923 --MESQRRTQEER-----STATRDALTLARHRLWRLRGYAEVGTPEIAKE
TH_3094|M.thermoresistible__bu --MSKRGGRVEDRRA--RGDQTRRDLIDAGRALFVDPGYFHTSVGDLVER
Mflv_3666|M.gilvum_PYR-GCK -----MPRVTDDH-----LAARRRQILDGARRCFAEYGYESATVRRLEQT
Mvan_2744|M.vanbaalenii_PYR-1 -----MPRVTDDH-----LAARRRQILDGARRCFAEYGYDRATVRRLEQT
MAB_4352c|M.abscessus_ATCC_199 -----MVPLRQAQ-----ALATRQRLVDVATELFALHGFTSVTTTSLSEA
MSMEG_1565|M.smegmatis_MC2_155 MRQTRAARSGPGRPAGTDSVDTRQRVIDAACRCFAQFGYGPATNNQIAEM
: * : : *: . :
Rv0078|M.tuberculosis_H37Rv AGV-TRGAMYHQFADKAALFRDVVEVVEQDVMARMATLVAASGAATPADA
Mb0080|M.bovis_AF2122/97 AGV-TRGAMYHQFADKAALFRDVVEVVEQDVMARMATLVAASGAATPADA
MMAR_0224|M.marinum_M AGV-TRGAMYHQFADKAALFGEVVEAVEQDVMTRMATSVAASGAATPADA
MUL_4890|M.ulcerans_Agy99 AGV-TRGAMYHQFADKAALFGEVVEAVEQDVMTRMATSVTTSGAATPADA
MAV_5253|M.avium_104 AGV-TRGAMYHQFADKAALFRAVVEAVEQDVMARMAVVVAESGASTPTDA
MLBr_02677|M.leprae_Br4923 ADT-TRGAVYHQFTDKAALFRDVVETVEQDAMAQIASVVASSGAKTPVDA
TH_3094|M.thermoresistible__bu SGVGTRGAFYHHFPDKAALFRAVFEDVEQDLTLRSIASPPEG--SDSWER
Mflv_3666|M.gilvum_PYR-GCK IGL-SRGAIFHHFRDKDTLFFELAR----EDAERMADVAAREGLIQVMRD
Mvan_2744|M.vanbaalenii_PYR-1 IGL-SRGAIFHHFRDKDTLFFELAR----EDAERMADVAAREGLIQVMRD
MAB_4352c|M.abscessus_ATCC_199 SGM-TRGALYHHFANMTEVMEAVFERAEGFLVAEVNHS--LTSIESPAER
MSMEG_1565|M.smegmatis_MC2_155 AGV-TAGSVYYHFGTKNKLFEAVCDDVYGKILTRVMLAVSGS--HSVVGL
. : *:.:::* :: : .
Rv0078|M.tuberculosis_H37Rv IRAAVDAWLEVSG-DPEVRQLIL---LDAPVVLGWAGFRDVAQRYSLGMT
Mb0080|M.bovis_AF2122/97 IRAAVDAWLEVSG-DPEVRQLVL---LDAPVVLGWAGFRDVAQRYSLGMT
MMAR_0224|M.marinum_M IRAAVDAWLEVSG-DPEVRQLIL---LDAPAVLGWAGFRDVAQRYSLGMT
MUL_4890|M.ulcerans_Agy99 IRAAVDAWLEVSG-DPEVRQLIL---LDAPAVLGWAGFCDVAQRYSLGMT
MAV_5253|M.avium_104 IRAAVDAWLEVSA-DPEVRQLIL---LDAPSVLGWAEFRDVAQRYSLGMT
MLBr_02677|M.leprae_Br4923 IRAKVDAWLEGLA-DPQVRQLIL---LYAPSVLGWAAFRDVAQHYSLGMT
TH_3094|M.thermoresistible__bu LTRGLHGFLDAAA-EPEVQRIIL---IDGPVVLGWQTLRSIEERSSLAMI
Mflv_3666|M.gilvum_PYR-GCK MLAAPDQFDWLAT-RLEIARKLR---NDPAFSQGWAER---SAELSAATT
Mvan_2744|M.vanbaalenii_PYR-1 MLAAPDQFNWLAT-RLEIARKLR---NDPAFSRGWAER---SAELSAATT
MAB_4352c|M.abscessus_ATCC_199 FLAIGSAVLDVLAREPIVQRIVF---VEAPMALGWSRWRALDGGRSLGLI
MSMEG_1565|M.smegmatis_MC2_155 LRAVLTESMRINHESPELAGFVATAPIDARRHRELAESFATQGARMADAL
: : :
Rv0078|M.tuberculosis_H37Rv EQ-LITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATAD-----DPKR
Mb0080|M.bovis_AF2122/97 EQ-LITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATAD-----DPKR
MMAR_0224|M.marinum_M EQ-LITEAIRAGQLDRHPVRPLAHVLIGALDEAAMFIATAD-----DPKR
MUL_4890|M.ulcerans_Agy99 EQ-LITEAIRAGQLDRHPVRPLAHVLIGALDEAAMFIATAD-----DPKR
MAV_5253|M.avium_104 EQ-LLTEAIRAGELAEQPVRPLAHVLIGALDEAAMVIATAD-----DPDR
MLBr_02677|M.leprae_Br4923 EQQLLSEASRARQLA----QPLDHVLIGKLYESAMAIRRHHRLPEASPAR
TH_3094|M.thermoresistible__bu QQ-ILRRAIADGSIEEQPVTALTHMLVSAVEEASLLIAHST-----DPER
Mflv_3666|M.gilvum_PYR-GCK ER-LRRQKQAGRLRDDVDGEVLRTYLELVLDGLVARLASGD-----DPEK
Mvan_2744|M.vanbaalenii_PYR-1 ER-LRRQKRAGRLRDDVPGDVLRTYLELVLDGLVARLASGD-----DPEK
MAB_4352c|M.abscessus_ATCC_199 QDILEELYRRGELVEAVDPQMAAQLILGAINESGMYAAAAP------SER
MSMEG_1565|M.smegmatis_MC2_155 TDAVRSGQDAGDIAADLDPVRVARLISAVVDGFAHAAVSAD------PDE
: : : . .
Rv0078|M.tuberculosis_H37Rv -------------AR------------RETRQVLRRLIDGMLNG------
Mb0080|M.bovis_AF2122/97 -------------AR------------RETRQVLRRLIDGMLNG------
MMAR_0224|M.marinum_M -------------AR------------RESRQVLRRLIDGMLND------
MUL_4890|M.ulcerans_Agy99 -------------AR------------RESRQVLRRLIDGMLND------
MAV_5253|M.avium_104 -------------AR------------RETRQVLQRLVDGMFDAR-----
MLBr_02677|M.leprae_Br4923 NQTGAAPTHREHVARPSCEALTRHIRHRSTRTRSHRGKRGELLPRAATSS
TH_3094|M.thermoresistible__bu --------AR-----------------SDAEAVLDTLLNALTRRRSRSR-
Mflv_3666|M.gilvum_PYR-GCK -----------------------------LSAVLDLVEASVRQP------
Mvan_2744|M.vanbaalenii_PYR-1 -----------------------------LGAVLDLVEASVRQQ------
MAB_4352c|M.abscessus_ATCC_199 S--------------------------SRAAEQLTLLCRGLLSPRSG---
MSMEG_1565|M.smegmatis_MC2_155 ------------------------------MDNMNELFQSLLLDTT----
.
Rv0078|M.tuberculosis_H37Rv --
Mb0080|M.bovis_AF2122/97 --
MMAR_0224|M.marinum_M --
MUL_4890|M.ulcerans_Agy99 --
MAV_5253|M.avium_104 --
MLBr_02677|M.leprae_Br4923 LL
TH_3094|M.thermoresistible__bu --
Mflv_3666|M.gilvum_PYR-GCK --
Mvan_2744|M.vanbaalenii_PYR-1 --
MAB_4352c|M.abscessus_ATCC_199 --
MSMEG_1565|M.smegmatis_MC2_155 --