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SDIAATMKCRLRVSRKRLVGTYGSMTHPNNPGTRRQADLSSRLTRRRHKLAPDPGIRRAILVAASMSVRE HGVRGLSVATVLDRAQLSTRAFYRHFESKDQLVAAVFLEVARVEAVRLRTLMAKATNPIEGVAAWIDGRL DLAFDDAVKADLRHLSMDAQSHLLNTPELVEPAYAETLEPLIEQLHLGVAQEVFHDVDPHSEARSIQGVV WANTEQQWASGDCRRDEVRESTVRFCLRGLGVAPDTIAQITAPD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1569 | - | - | 100% (255) | putative regulatory protein |
| M. marinum M | MMAR_5312 | - | 4e-10 | 29.35% (184) | hypothetical protein MMAR_5312 |
| M. marinum M | MMAR_4752 | - | 2e-06 | 24.73% (186) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2534 | - | 2e-05 | 24.54% (216) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2097 | - | 3e-11 | 28.40% (169) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2506 | - | 2e-05 | 24.54% (216) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 2e-05 | 22.73% (220) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0599 | - | 3e-08 | 24.87% (197) | TetR family transcriptional regulator |
| M. avium 104 | MAV_2439 | - | 7e-62 | 60.51% (195) | transcriptional regulator, TetR family protein, putative |
| M. smegmatis MC2 155 | MSMEG_6009 | - | 5e-07 | 24.63% (203) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2894 | - | 4e-16 | 33.33% (189) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_3464 | - | 1e-142 | 98.82% (255) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4608 | - | 3e-12 | 26.70% (191) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_0599|M.abscessus_ATCC_1997 ----------------------------------MDKVSEVRESDALRAG
MSMEG_6009|M.smegmatis_MC2_155 -----------------------------------------MAPDTP---
Mb2534|M.bovis_AF2122/97 -------------------------------MTASAPDGRPGQPEATNRR
Rv2506|M.tuberculosis_H37Rv -------------------------------MTASAPDGRPGQPEATNRR
MMAR_1569|M.marinum_M MSDIAATMKCRLRVSRKRLVGTYGSMTHPNNPGTRRQADLSSRLTRRRHK
MUL_3464|M.ulcerans_Agy99 MSDIAATMKCRLRVSRKRLVGTYGSMTHPNNPGTRRQADLSSRLTRRRHK
MAV_2439|M.avium_104 --------------------------------------------------
Mflv_2097|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4608|M.vanbaalenii_PYR-1 -----------------------------------------------MQP
TH_2894|M.thermoresistible__bu -----------------------------------------------VAT
MLBr_00815|M.leprae_Br4923 -----------------MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSN
MAB_0599|M.abscessus_ATCC_1997 GSPQPSRRDELLSLAAEMFAERGLRATTVRDIADAAGILSGSLYHHFDSK
MSMEG_6009|M.smegmatis_MC2_155 -SQPASRRDELLQLAATMFADRGLKATTVRDIADSAGILSGSLYHHFKSK
Mb2534|M.bovis_AF2122/97 SQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNK
Rv2506|M.tuberculosis_H37Rv SQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNK
MMAR_1569|M.marinum_M LAPDPGIRRAILVAASMSVREHGVRGLSVATVLDRAQLSTRAFYRHFESK
MUL_3464|M.ulcerans_Agy99 LAPDPGIRRAILVAASMSVREHGVRGLSVATVLDRAQLSTRAFYRHFESK
MAV_2439|M.avium_104 ------MRRAILDAASTTLRRQGVDGLSIAAVLSRASLSTRAFYRHFGSK
Mflv_2097|M.gilvum_PYR-GCK -----------MEAAYRCLADPHAGPVSMAAILGTAGVSSRAFYRHFESK
Mvan_4608|M.vanbaalenii_PYR-1 GPDHDGDRRRIIEAAYRCLAQPHAGPIPMTSILRSAGLSSRAFYRHFLSK
TH_2894|M.thermoresistible__bu DSPASEDRKRIIDAAYQCLSERHVNPVSVAAILARAECSSRAFYRHFESK
MLBr_00815|M.leprae_Br4923 RLSRDKRRGQLLIVASDVFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSK
: * . : : * :*:** .*
MAB_0599|M.abscessus_ATCC_1997 EAIVDELLRDFLEGLFARYREIAAANLN-PVDTLKGLFLASFDAIETKHA
MSMEG_6009|M.smegmatis_MC2_155 EQMVEEVLRDFLDWLFGRYQQILDTATS-PLEKLTGLFMASFEAIEHRHA
Mb2534|M.bovis_AF2122/97 ESLLVELLVGVSARLLAGARDVTTRSAN-LAAALDGLIEFHLDFALGEAD
Rv2506|M.tuberculosis_H37Rv ESLLVELLVGVSARLLAGARDVTTRSAN-LAAALDGLIEFHLDFALGEAD
MMAR_1569|M.marinum_M DQLVAAVFLEVARVEAVRLRTLMAKATN-PIEGVAAWIDGRLDLAFDDAV
MUL_3464|M.ulcerans_Agy99 DQLVAAMFLEVARVEAVRLRTLMAKATN-PIEGVAAWIDGRLDLAFDDAV
MAV_2439|M.avium_104 DELVAAVFLEHARAEKRRLRRRMTGAAS-EAEAVAAWIDGRLDLAFDDRI
Mflv_2097|M.gilvum_PYR-GCK DDLFLALLEQECSAVVGQVDRVADAAQGSPADQLAAWIEAMFDIVVDPRQ
Mvan_4608|M.vanbaalenii_PYR-1 DDLFLALLRQECEAVIAQVDRIADAAVGSPADQLADWIAAMFDIIVDPQQ
TH_2894|M.thermoresistible__bu DALFLAMVEEESAALTRRLDRIVAEHPGTPIEQLQAWVEQLFALVYDPAL
MLBr_00815|M.leprae_Br4923 LELYLAVLERHMNNLVSSVQQALRTTTN-NRQRLHAAVQAFFDFIEHDGQ
: :. . : . :
MAB_0599|M.abscessus_ATCC_1997 QVAIYQAEAPRLLSQERFAYLNELNTEQRQLWLEVLRDGIAQGYFRPDLD
MSMEG_6009|M.smegmatis_MC2_155 QVVIYQDEAKRLSDLPQFDFVETRNKEQRKMWVDILQEGVADGSFRPDLD
Mb2534|M.bovis_AF2122/97 LIRIQDRDLAHLPAVAER-QVRKAQRQYVEVWVGVLRELNPG---LAEAD
Rv2506|M.tuberculosis_H37Rv LIRIQDRDLAHLPAVAER-QVRKAQRQYVEVWVGVLRELNPG---LAEAD
MMAR_1569|M.marinum_M KADLRHLSMDAQSHLLNTPELVEPAYAETLEPLIEQLHLGVAQEVFHDVD
MUL_3464|M.ulcerans_Agy99 KADLRHLSMGAQSHLLNAPELVEPAYAETLEPLIEQLHLGVAQEVFHDVD
MAV_2439|M.avium_104 GNDLRRLSLEAQSQAMGPAELIQPAYAEMLEPLRDALQRGSQNGVFHDVD
Mflv_2097|M.gilvum_PYR-GCK RLQLTVIDSEEVRTAKGYRQTRDRLHAARERGLAEILRRGLRDGSFPLTE
Mvan_4608|M.vanbaalenii_PYR-1 RLQLTVIDSDEVRAAKGYREMRERLHAERERSLAEILRRGRRDGSFPLAE
TH_2894|M.thermoresistible__bu REHMQVIDSDEVRSAKGFREVRERAHIERERSLRTILTRGRADGSMPLTD
MLBr_00815|M.leprae_Br4923 GYRLIFENDNITEP-----RVAAQVRVATESCIDAVFALISADSRLDPHR
: . :
MAB_0599|M.abscessus_ATCC_1997 VAVVYRFIRDATWVSVRWFRPGG-SRTAQEVAEQYLSIVLGGITVGSFSN
MSMEG_6009|M.smegmatis_MC2_155 VDLVYRFIRDTTWVSVRWYKPGG-PLSAEQVGQQYLAIVLGGITQSQGDK
Mb2534|M.bovis_AF2122/97 ARLMAHAVFGLLNSTPHSMKAAD-SKPARTVRARAVLRAMTVAALSAADR
Rv2506|M.tuberculosis_H37Rv ARLMAHAVFGLLNSTPHSMKAAD-SKPARTVRARAVLRAMTVAALSAADR
MMAR_1569|M.marinum_M PHSEARSIQGVVWANTEQQWASG-DCRRDEVRESTVRFCLRGLGVAPDTI
MUL_3464|M.ulcerans_Agy99 PHSEARSIQGVVWANTEQQWASG-DCRRDEVRESTVRFCLRGLGVAPDTI
MAV_2439|M.avium_104 PVTQAQFIHGVVWTGIARQWASG-DCDRDDLRRRVQRFCLRGLGIADEVI
Mflv_2097|M.gilvum_PYR-GCK PEADAVAINAVVSRVLNTQTTDE-PEARKKALVAVLDFALRAVGAAAR--
Mvan_4608|M.vanbaalenii_PYR-1 PEIDAVAVNALVSRLLVRQTTDD-PQARKQAEVAVLDFALRAVGAVPGGQ
TH_2894|M.thermoresistible__bu PECDAVAIGAVVARALLEQTDLT-DDEYRVGVECVMDFALRAIGADHTPY
MLBr_00815|M.leprae_Br4923 ARMVAVGLVGISVDCARYWLDTNRPISKSDAVEGTVQFAWGGLSHVPLTR
:
MAB_0599|M.abscessus_ATCC_1997 SPEK------
MSMEG_6009|M.smegmatis_MC2_155 HA--------
Mb2534|M.bovis_AF2122/97 CL--------
Rv2506|M.tuberculosis_H37Rv CL--------
MMAR_1569|M.marinum_M AQITAPD---
MUL_3464|M.ulcerans_Agy99 AQITAPD---
MAV_2439|M.avium_104 DRVCFVMERG
Mflv_2097|M.gilvum_PYR-GCK ----------
Mvan_4608|M.vanbaalenii_PYR-1 DTRR------
TH_2894|M.thermoresistible__bu RR--------
MLBr_00815|M.leprae_Br4923 L---------