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ARQARAGVTRRKIITAAVDLFAEIGYPATGLGEIIERADMTKGALYYHFDSKEALAEAIIAESGASMLAA FQNITETSSPALENLIHGLFVVCDFTRTDRVADIGLHLLQTFAGINDTTARVYASWLDAISAQLHRAAAE GDLREGLDPGAVADVVLSALLGAEALTRAGTSGTDLRERLVRTWDLLLPALVEPASLDYFREFLARESMR RSPGTD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2193 | - | - | 100% (217) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_2195 | - | 3e-25 | 33.33% (204) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5424 | - | 6e-09 | 29.31% (174) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1047 | - | 6e-09 | 27.50% (160) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3637 | - | 9e-10 | 30.06% (173) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1019 | - | 6e-09 | 27.50% (160) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 9e-08 | 30.00% (90) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4352c | - | 3e-11 | 27.55% (196) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1444 | - | 2e-08 | 50.00% (56) | TetR family transcriptional regulator |
| M. avium 104 | MAV_1141 | - | 3e-46 | 41.41% (227) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3094 | - | 7e-11 | 29.59% (196) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_4765 | - | 2e-08 | 25.15% (163) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5860 | - | 1e-09 | 29.94% (167) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2193|M.smegmatis_MC2_155 ------------------------------MARQARAGVTRRKIITAAVD
MAV_1141|M.avium_104 ------------------------------MARQVRSEATRQKILDSAIE
Mb1047|M.bovis_AF2122/97 ----------------------------------MTGTERRHQLIGIARS
Rv1019|M.tuberculosis_H37Rv ----------------------------------MTGTERRHQLIGIARS
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
MAB_4352c|M.abscessus_ATCC_199 ----------------------------MVPLRQAQALATRQRLVDVATE
TH_3094|M.thermoresistible__bu ----------------------MSKRGGRVEDRRARGDQTRRDLIDAGRA
Mflv_3637|M.gilvum_PYR-GCK ---------------MENETLSVSAGRKRGRPVAADSEQTRRTVLAAARD
MUL_4765|M.ulcerans_Agy99 -------------------MMQLTASRGPGRPPAAKADDTRRRIVGAARE
MMAR_1444|M.marinum_M ----------------------------------MRAASTRERLVTEAMR
Mvan_5860|M.vanbaalenii_PYR-1 ----------------------------------MADPSTRSRILDATAE
* ::
MSMEG_2193|M.smegmatis_MC2_155 LFAEIGYPATGLGEIIERADM--TKGALYYHFDS-KEALAEAIIAESGAS
MAV_1141|M.avium_104 VFGEVGYAAAGWSTIIERTGM--TKGALYHHFDS-KESLASNIIEEGSDR
Mb1047|M.bovis_AF2122/97 LFAERGYDGTSIEEIAQRANV--SKPVVYEHFGG-KEGLYAVVVDREMSA
Rv1019|M.tuberculosis_H37Rv LFAERGYDGTSIEEIAQRANV--SKPVVYEHFGG-KEGLYAVVVDREMSA
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGV--SKPVLYQHFSS-KLELYLAVLERHMNN
MAB_4352c|M.abscessus_ATCC_199 LFALHGFTSVTTTSLSEASGM--TRGALYHHFAN-MTEVMEAVFERAEGF
TH_3094|M.thermoresistible__bu LFVDPGYFHTSVGDLVERSGVG-TRGAFYHHFPD-KAALFRAVFEDVEQD
Mflv_3637|M.gilvum_PYR-GCK IIAERGYQATTFQQIAQRAGV--SRPTLHYYFAT-REDLYDALLADVCER
MUL_4765|M.ulcerans_Agy99 VFSERGYDGATFQAIAVSADL--TRPAINHYFAS-KQALYREVVVQTNEL
MMAR_1444|M.marinum_M LFGERGYHATSVAQIEAAAGLASGSGALYHHFDS-KESLLEAGIDRQLDR
Mvan_5860|M.vanbaalenii_PYR-1 LYRRQGMPATGLKQISAAAQAP--FGSIYHHFPGGKEAISVEVIRREGIR
: * . : : . :* : .
MSMEG_2193|M.smegmatis_MC2_155 ---MLAAFQNITETSSPALENLIHGLFVVCDFTRTDRVADIGLHLLQ-TF
MAV_1141|M.avium_104 ---LLSAFRNVCGSSSPGLENLVHGTFTIVEVLRSDKMVRAAAQLAT-AL
Mb1047|M.bovis_AF2122/97 ---LLDGITSSLTNNRSRVR--VERVALALLTYVEERTDGFRIMIRD-SP
Rv1019|M.tuberculosis_H37Rv ---LLDGITSSLTNNRSRVR--VERVALALLTYVEERTDGFRIMIRD-SP
MLBr_00815|M.leprae_Br4923 ---LVSSVQQALRTTTNNRQR-LHAAVQAFFDFIEHDGQGYRLIFEN-DN
MAB_4352c|M.abscessus_ATCC_199 ---LVAEVNHSLTSIESPAERFLAIGSAVLDVLAREPIVQRIVFVEAPMA
TH_3094|M.thermoresistible__bu ---LTLRSIASPPEGSDSWER-LTRGLHGFLDAAAEPEVQRIILIDGPVV
Mflv_3637|M.gilvum_PYR-GCK ---LGRCAAAAAGQDSLRGQLAAFMAEMNRLAVAEPAMMKLVVTARIDHH
MUL_4765|M.ulcerans_Agy99 ---VVAAGVERARSVQTLLGQLCTFVMVAKEADASHPATTAFLATAVLES
MMAR_1444|M.marinum_M RRAMGDLRALFAGLGDPRSELTLLGRYVLAVLDEESQLLQIAAALPTGRP
Mvan_5860|M.vanbaalenii_PYR-1 ---YAELVGAQLADTDPLTGIPQLFEKAGRDLEAQDYSEACSIETIALEV
MSMEG_2193|M.smegmatis_MC2_155 AGINDT------TARVYASWLDAISAQLHRAAAEGDLREGLDPGAVADVV
MAV_1141|M.avium_104 SGFNGA------ASRFYANLVLETAQEARRAIKEGDLRDDIDPDVLSASL
Mb1047|M.bovis_AF2122/97 ASIS---------SGTYSSLLNDAVSQVSSILAGDFARRGLDP-DLAPLY
Rv1019|M.tuberculosis_H37Rv ASIS---------SGTYSSLLNDAVSQVSSILAGDFARRGLDP-DLAPLY
MLBr_00815|M.leprae_Br4923 ITEP----------RVAAQVRVATESCIDAVFALISADSRLDP-HRARMV
MAB_4352c|M.abscessus_ATCC_199 LGWSRW------RALDGGRSLGLIQDILEELYRRGELVEAVDPQMAAQLI
TH_3094|M.thermoresistible__bu LGWQTL------RSIEERSSLAMIQQILRRAIADGSIEEQPVT-ALTHML
Mflv_3637|M.gilvum_PYR-GCK GARIGTGEGRGAATDIVSTVHDFYDAVVLAAAARGELPAGHDPHAVADML
MUL_4765|M.ulcerans_Agy99 QRHPELRR---SDHDAVAATREFLDTAVRDAIQRGELEAGVDASQLAEAL
MMAR_1444|M.marinum_M AQLDDA------YAALFAGLNAELTDWVKELVPTISKQQALTIGTVAVNS
Mvan_5860|M.vanbaalenii_PYR-1 ASTNER------LRVEAAEVFQSWLTGLAAWFGRLALTEPECR-RLAMIT
:
MSMEG_2193|M.smegmatis_MC2_155 LSALLGAEALT-------RAGTSGTDLRERLVRTWDLLLPALVEPASLDY
MAV_1141|M.avium_104 MGTIFGARLIASTISGHGRIGDIIGDPTARLHQIWSLLLPGIVSQASLPY
Mb1047|M.bovis_AF2122/97 AQALVGSVSMT---------AQWWLDAREPKKEVVAAHLVNLVWNG-LTH
Rv1019|M.tuberculosis_H37Rv AQALVGSVSMT---------AQWWLDAREPKKEVVAAHLVNLVWNG-LTH
MLBr_00815|M.leprae_Br4923 AVGLVGISVDC---------ARYWLDTNRPISKSDAVEGTVQFAWGGLSH
MAB_4352c|M.abscessus_ATCC_199 LGAINESGMYA---------AAAPSERSSRAAEQLTLLCRGLLSPRSG--
TH_3094|M.thermoresistible__bu VSAVEEASLLIAH-------STDPERARSDAEAVLDTLLNALTRRRSRSR
Mflv_3637|M.gilvum_PYR-GCK AAVFWGLGFHAR-----MLTADIGVDGVPEVARQLLSVLDSGLLDGALRA
MUL_4765|M.ulcerans_Agy99 LLLLCGVGFYAG--------FVGSYRDMENILDTLCKMMAGTLWKPRS--
MMAR_1444|M.marinum_M LFGNRATSTVFR-------TPVADLTDEQYIAEWATMLVNRIELLRKL--
Mvan_5860|M.vanbaalenii_PYR-1 LTALEGAFVLCR--------TLRSIDPIIAAGHGVQAAVRAAATTRRS--
MSMEG_2193|M.smegmatis_MC2_155 FREFLARESMRRS---PGTD----
MAV_1141|M.avium_104 FEQFLRREGMRHATANPGAEPEGE
Mb1047|M.bovis_AF2122/97 LEADPRLQDE--------------
Rv1019|M.tuberculosis_H37Rv LEADPRLQDE--------------
MLBr_00815|M.leprae_Br4923 VPLTRL------------------
MAB_4352c|M.abscessus_ATCC_199 ------------------------
TH_3094|M.thermoresistible__bu ------------------------
Mflv_3637|M.gilvum_PYR-GCK PADA--------------------
MUL_4765|M.ulcerans_Agy99 ------------------------
MMAR_1444|M.marinum_M ------------------------
Mvan_5860|M.vanbaalenii_PYR-1 ------------------------