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M. thermoresistible (build 8) TH_4497 (-)

annotation: putative transcriptional regulator, TetR family
coordinates: 238738 - 239367
length: 210

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4497--100% (210)putative transcriptional regulator, TetR family
M. thermoresistible (build 8)TH_3734-8e-9181.50% (200) PUTATIVE putative transcriptional regulator, TetR family
M. thermoresistible (build 8)TH_2894-3e-2536.13% (191) PUTATIVE transcriptional regulator, TetR family

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3076c-5e-0629.85% (134) AsnC family transcriptional regulator
M. gilvum PYR-GCKMflv_2097-2e-2637.57% (189) TetR family transcriptional regulator
M. tuberculosis H37RvRv3050c-5e-0629.85% (134) AsnC family transcriptional regulator
M. leprae Br4923MLBr_01733-3e-0640.91% (66) putative TetR-family transcriptional regulator
M. abscessus ATCC 19977MAB_2812-3e-0745.90% (61) TetR family transcriptional regulator
M. marinum MMMAR_1569-1e-1530.00% (190) putative regulatory protein
M. avium 104MAV_1858-8e-1829.59% (196) transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_3142-5e-0726.00% (150) HTH-type transcriptional repressor AcnR
M. ulcerans Agy99MUL_3464-1e-1530.00% (190) putative regulatory protein
M. vanbaalenii PYR-1Mvan_4608-3e-2936.45% (203) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_1569|M.marinum_M               --MSDIAATMKCRLRVSRKRLVGTYGSMTHPNNPGTRRQADLSSRLTRRR
MUL_3464|M.ulcerans_Agy99           --MSDIAATMKCRLRVSRKRLVGTYGSMTHPNNPGTRRQADLSSRLTRRR
Mflv_2097|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4608|M.vanbaalenii_PYR-1       -------------------------------------------------M
TH_4497|M.thermoresistible__bu      -----------------------------------------------VAE
Mb3076c|M.bovis_AF2122/97           -----------------------------MVRIPRPHPSAKPGVKVDARS
Rv3050c|M.tuberculosis_H37Rv        -----------------------------MVRIPRPHPSAKPGVKVDARS
MLBr_01733|M.leprae_Br4923          MTRRSIHTRKPLKWSGCAGQHVRSGKVFDVGRISLSYPSMKPGVKIDARS
MAV_1858|M.avium_104                --------------------------------------------------
MAB_2812|M.abscessus_ATCC_1997      -----------------------------------------MATRGRGRP
MSMEG_3142|M.smegmatis_MC2_155      ------------------------------------------------MP
                                                                                      

MMAR_1569|M.marinum_M               HKLAPD-PGIRRAILVAASMSVRE-----HGVRGLSVATVLDRAQLSTRA
MUL_3464|M.ulcerans_Agy99           HKLAPD-PGIRRAILVAASMSVRE-----HGVRGLSVATVLDRAQLSTRA
Mflv_2097|M.gilvum_PYR-GCK          --------------MEAAYRCLAD-----PHAGPVSMAAILGTAGVSSRA
Mvan_4608|M.vanbaalenii_PYR-1       QPGPDH-DGDRRRIIEAAYRCLAQ-----PHAGPIPMTSILRSAGLSSRA
TH_4497|M.thermoresistible__bu      TRTVDR-SSERQHIIDAAYRCLHR-----NAGSAVSITEILDEAGLGTRA
Mb3076c|M.bovis_AF2122/97           ERWREHRKKVRNEIVDAAFRAIDR-----LGP-ELSVRQIAEEAGTAKPK
Rv3050c|M.tuberculosis_H37Rv        ERWREHRKKVRNEIVDAAFRAIDR-----LGP-ELSVRQIAEEAGTAKPK
MLBr_01733|M.leprae_Br4923          ERWREHRKKVRGEIVDAAFRALDR-----LGP-EVSVREIAEEAGTAKPK
MAV_1858|M.avium_104                -MSDHRRPTERDAIMRAAYRLISEGAAGPSASSSTSIENILRVARVNRRV
MAB_2812|M.abscessus_ATCC_1997      SGAPYDRKLRTEELLDAAERAIRN------SGGTVSIAEVAREAGFARSA
MSMEG_3142|M.smegmatis_MC2_155      RVTDDHLAARRRQILDGARRCFAK-----YGYESATVRRLEETIGLSRGA
                                                  : .*   .             .:  :          

MMAR_1569|M.marinum_M               FYRHFESKDQLVAAVFLEVARVEAVRLRTLMAKATN-PIEGVAAWIDGRL
MUL_3464|M.ulcerans_Agy99           FYRHFESKDQLVAAMFLEVARVEAVRLRTLMAKATN-PIEGVAAWIDGRL
Mflv_2097|M.gilvum_PYR-GCK          FYRHFESKDDLFLALLEQECSAVVGQVDRVADAAQGSPADQLAAWIEAMF
Mvan_4608|M.vanbaalenii_PYR-1       FYRHFLSKDDLFLALLRQECEAVIAQVDRIADAAVGSPADQLADWIAAMF
TH_4497|M.thermoresistible__bu      FYRNFSTKHDLLLELFRRDRDAVRAQLREVVARAEG-PVEALRAWMAHML
Mb3076c|M.bovis_AF2122/97           IYRHFTDKSDLLEAIGMRLRDMLWAAIFPSLDLATDSAREVIRRSVEEYV
Rv3050c|M.tuberculosis_H37Rv        IYRHFTDKSDLLEAIGMRLRDMLWAAIFPSLDLATDSAREVIRRSVEEYV
MLBr_01733|M.leprae_Br4923          IYRHFTDKSDLFEAIGIRLRDMLWAAIFPAIDLATDSAREIIRRSVDEYV
MAV_1858|M.avium_104                FYRHFASKDDLIIAMQEWAGDLILADLQKAVAAADT-PAAAVAAWIEDYL
MAB_2812|M.abscessus_ATCC_1997      CYAVFPTKADLLRSLSRRHADRLISGAWQHSMVGDT--RDQIRAFSTLVI
MSMEG_3142|M.smegmatis_MC2_155      IFHHFKDKDTLFFELAREDAERMAEVAAR----------EGLIQVMRDLL
                                     :  *  *  *.  :                          :       .

MMAR_1569|M.marinum_M               DLAFDDAVKADLRHLSMDAQSHLLNTPELVEPAYAETLEPLIEQLHLGVA
MUL_3464|M.ulcerans_Agy99           DLAFDDAVKADLRHLSMGAQSHLLNAPELVEPAYAETLEPLIEQLHLGVA
Mflv_2097|M.gilvum_PYR-GCK          DIVVDPRQRLQLTVIDSEEVRTAKGYRQTRDRLHAARERGLAEILRRGLR
Mvan_4608|M.vanbaalenii_PYR-1       DIIVDPQQRLQLTVIDSDEVRAAKGYREMRERLHAERERSLAEILRRGRR
TH_4497|M.thermoresistible__bu      DLVSNPRKRKRMATFYSEEMRRTPGYDRELEIMSAADQASIAAILHRGKA
Mb3076c|M.bovis_AF2122/97           NLVDQHPNVLRVFIQGRSAKQSEATVRTLNE--GREITLAMAEMFNNELR
Rv3050c|M.tuberculosis_H37Rv        NLVDQHPNVLRVFIQGRSAKQSEATVRTLNE--GREITLAMAEMFNNELR
MLBr_01733|M.leprae_Br4923          SLVDKHPNVLRVFIQGRFSAQSEATVRTLDE--GREITLTMAEMFNNELR
MAV_1858|M.avium_104                SIGWQEARFRDALAFMSAEVIGAPGIAAALEVTYDRHRAVLTEALAAGLA
MAB_2812|M.abscessus_ATCC_1997      DWISAEP------ELYIALDRDLTAQEQLDHGVFDLIAQVTEEHLHAQFP
MSMEG_3142|M.smegmatis_MC2_155      AAPEQYDWLATRLEIAR-KLRNDPDFHRGWAERSAELTAATTERLRRQKQ
                                                                                :     

MMAR_1569|M.marinum_M               QEVFHDVDPHSEARSIQGVVWANTEQQWASGDC-----RRDEVRESTVRF
MUL_3464|M.ulcerans_Agy99           QEVFHDVDPHSEARSIQGVVWANTEQQWASGDC-----RRDEVRESTVRF
Mflv_2097|M.gilvum_PYR-GCK          DGSFPLTEPEADAVAINAVVSRVLNTQTTDEPE-----ARKKALVAVLDF
Mvan_4608|M.vanbaalenii_PYR-1       DGSFPLAEPEIDAVAVNALVSRLLVRQTTDDPQ-----ARKQAEVAVLDF
TH_4497|M.thermoresistible__bu      EGIFTECAPESDARTIRAAVEAALLDRFQQKTTG----SVADEVDHLMGF
Mb3076c|M.bovis_AF2122/97           EMELNRAALELAAFAAFGSAASATEWWLGPEPDSPRRMPREQFVAHLTTI
Rv3050c|M.tuberculosis_H37Rv        EMELNRAALELAAFAAFGSAASATEWWLGPEPDSPRRMPREQFVAHLTTI
MLBr_01733|M.leprae_Br4923          EMELNRAASELAAFAAFGSVASATEWWLGPEPDSPRRMPREQFVAHLTII
MAV_1858|M.avium_104                DGSLPNAHPELDSFAIHAVTVRHLEARIRGRLDS----DFREVRDQIVTL
MAB_2812|M.abscessus_ATCC_1997      GDQMTRLAPIWSRLAVGGVLMTINWWSASRTMT------QDDLIGYIVET
MSMEG_3142|M.smegmatis_MC2_155      AGRLRDDVPSAVLHIYLDVVLDGLVARLASGEDSKNLSAVLDLVEASVRQ
                                       :                                     .        

MMAR_1569|M.marinum_M               CLRGLGVAPDTIAQITAPD--------------
MUL_3464|M.ulcerans_Agy99           CLRGLGVAPDTIAQITAPD--------------
Mflv_2097|M.gilvum_PYR-GCK          ALRAVGAAAR-----------------------
Mvan_4608|M.vanbaalenii_PYR-1       ALRAVGAVPGGQDTRR-----------------
TH_4497|M.thermoresistible__bu      VLRGLGAAGMEGAPDDR----------------
Mb3076c|M.bovis_AF2122/97           MMGVIVGTAEALGIAVDPDQPIHDAVPNNPAVR
Rv3050c|M.tuberculosis_H37Rv        MMGVIVGTAEALGIAVDPDQPIHDAVPNNPAVR
MLBr_01733|M.leprae_Br4923          MMAVIVGTAETLGISMNPDRPIHDAVPLDRSAS
MAV_1858|M.avium_104                MLTGLSAPAVYRTATR-----------------
MAB_2812|M.abscessus_ATCC_1997      FAEGIGEGSRLVAANC-----------------
MSMEG_3142|M.smegmatis_MC2_155      QPKPAPAVSTDHSFSDES---------------