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MSDIAATMKCRLRVSRKRLVGTYGSMTHPNNPGTRRQADLSSRLTRRRHKLAPDPGIRRAILVAASMSVR EHGVRGLSVATVLDRAQLSTRAFYRHFESKDQLVAAMFLEVARVEAVRLRTLMAKATNPIEGVAAWIDGR LDLAFDDAVKADLRHLSMGAQSHLLNAPELVEPAYAETLEPLIEQLHLGVAQEVFHDVDPHSEARSIQGV VWANTEQQWASGDCRRDEVRESTVRFCLRGLGVAPDTIAQITAPD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3464 | - | - | 100% (255) | putative regulatory protein |
| M. ulcerans Agy99 | MUL_4386 | - | 3e-09 | 30.43% (184) | hypothetical protein MUL_4386 |
| M. ulcerans Agy99 | MUL_0323 | - | 3e-06 | 23.78% (185) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2534 | - | 8e-06 | 24.07% (216) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2097 | - | 6e-11 | 28.40% (169) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2506 | - | 8e-06 | 24.07% (216) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0599 | - | 9e-09 | 25.87% (201) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1569 | - | 1e-142 | 98.82% (255) | putative regulatory protein |
| M. avium 104 | MAV_2439 | - | 5e-61 | 60.00% (195) | transcriptional regulator, TetR family protein, putative |
| M. smegmatis MC2 155 | MSMEG_0343 | - | 9e-07 | 26.47% (102) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_2894 | - | 9e-16 | 33.33% (189) | PUTATIVE transcriptional regulator, TetR family |
| M. vanbaalenii PYR-1 | Mvan_4608 | - | 1e-11 | 26.18% (191) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2534|M.bovis_AF2122/97 -------------------------------MTASAPDGRPGQPEATNRR
Rv2506|M.tuberculosis_H37Rv -------------------------------MTASAPDGRPGQPEATNRR
MUL_3464|M.ulcerans_Agy99 MSDIAATMKCRLRVSRKRLVGTYGSMTHPNNPGTRRQADLSSRLTRRRHK
MMAR_1569|M.marinum_M MSDIAATMKCRLRVSRKRLVGTYGSMTHPNNPGTRRQADLSSRLTRRRHK
MAV_2439|M.avium_104 --------------------------------------------------
Mflv_2097|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4608|M.vanbaalenii_PYR-1 -----------------------------------------------MQP
TH_2894|M.thermoresistible__bu -----------------------------------------------VAT
MSMEG_0343|M.smegmatis_MC2_155 -------------------------------MHSGGVLIVVDSPPGTAKA
MAB_0599|M.abscessus_ATCC_1997 ----------------------------------MDKVSEVRESDALRAG
Mb2534|M.bovis_AF2122/97 SQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNK
Rv2506|M.tuberculosis_H37Rv SQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNK
MUL_3464|M.ulcerans_Agy99 LAPDPGIRRAILVAASMSVREHGVRGLSVATVLDRAQLSTRAFYRHFESK
MMAR_1569|M.marinum_M LAPDPGIRRAILVAASMSVREHGVRGLSVATVLDRAQLSTRAFYRHFESK
MAV_2439|M.avium_104 ------MRRAILDAASTTLRRQGVDGLSIAAVLSRASLSTRAFYRHFGSK
Mflv_2097|M.gilvum_PYR-GCK -----------MEAAYRCLADPHAGPVSMAAILGTAGVSSRAFYRHFESK
Mvan_4608|M.vanbaalenii_PYR-1 GPDHDGDRRRIIEAAYRCLAQPHAGPIPMTSILRSAGLSSRAFYRHFLSK
TH_2894|M.thermoresistible__bu DSPASEDRKRIIDAAYQCLSERHVNPVSVAAILARAECSSRAFYRHFESK
MSMEG_0343|M.smegmatis_MC2_155 RTRDPDRKNRILLAASELIGRRGFHAVSIADIGNAAGITGSGVYRHFESK
MAB_0599|M.abscessus_ATCC_1997 GSPQPSRRDELLSLAAEMFAERGLRATTVRDIADAAGILSGSLYHHFDSK
: * . : : * ..*:** .*
Mb2534|M.bovis_AF2122/97 ESLLVELLVGVSARLLAGARDVTTRSAN-----LAAALDGLIEFHLDFAL
Rv2506|M.tuberculosis_H37Rv ESLLVELLVGVSARLLAGARDVTTRSAN-----LAAALDGLIEFHLDFAL
MUL_3464|M.ulcerans_Agy99 DQLVAAMFLEVARVEAVRLRTLMAKATN-PIEGVAAWIDGRLDLAFDDAV
MMAR_1569|M.marinum_M DQLVAAVFLEVARVEAVRLRTLMAKATN-PIEGVAAWIDGRLDLAFDDAV
MAV_2439|M.avium_104 DELVAAVFLEHARAEKRRLRRRMTGAAS-EAEAVAAWIDGRLDLAFDDRI
Mflv_2097|M.gilvum_PYR-GCK DDLFLALLEQECSAVVGQVDRVADAAQGSPADQLAAWIEAMFDIVVDPRQ
Mvan_4608|M.vanbaalenii_PYR-1 DDLFLALLRQECEAVIAQVDRIADAAVGSPADQLADWIAAMFDIIVDPQQ
TH_2894|M.thermoresistible__bu DALFLAMVEEESAALTRRLDRIVAEHPGTPIEQLQAWVEQLFALVYDPAL
MSMEG_0343|M.smegmatis_MC2_155 SAILVALFDQVIDDLIAEEKRILDETDD-----LPTALAELIEGQVEFVI
MAB_0599|M.abscessus_ATCC_1997 EAIVDELLRDFLEGLFARYREIAAANLN-----PVDTLKGLFLASFDAIE
. :. :. . : : :
Mb2534|M.bovis_AF2122/97 GEADLIRIQDRDLAHLPAVAERQVRKAQRQY-VEVWVGVLRE--LNPG-L
Rv2506|M.tuberculosis_H37Rv GEADLIRIQDRDLAHLPAVAERQVRKAQRQY-VEVWVGVLRE--LNPG-L
MUL_3464|M.ulcerans_Agy99 -KADLRHLSMGAQSHLLNAPELVEPAYAETL-EPLIEQLHLG--VAQEVF
MMAR_1569|M.marinum_M -KADLRHLSMDAQSHLLNTPELVEPAYAETL-EPLIEQLHLG--VAQEVF
MAV_2439|M.avium_104 -GNDLRRLSLEAQSQAMGPAELIQPAYAEML-EPLRDALQRG--SQNGVF
Mflv_2097|M.gilvum_PYR-GCK -RLQLTVIDSEEVRTAKGYRQTRDRLHAARE-RGLAEILRRG--LRDGSF
Mvan_4608|M.vanbaalenii_PYR-1 -RLQLTVIDSDEVRAAKGYREMRERLHAERE-RSLAEILRRG--RRDGSF
TH_2894|M.thermoresistible__bu -REHMQVIDSDEVRSAKGFREVRERAHIERE-RSLRTILTRG--RADGSM
MSMEG_0343|M.smegmatis_MC2_155 GDRQLAQVYHNEINNLPEEDRRRLRRKQRLY-LEEWVHLVNE--LRED-L
MAB_0599|M.abscessus_ATCC_1997 TKHAQVAIYQAEAPRLLSQERFAYLNELNTEQRQLWLEVLRDGIAQGYFR
: . :
Mb2534|M.bovis_AF2122/97 AEADARLMAHAVFGLLNSTPHSMKAADS---KPARTVRARAVLRAMTVAA
Rv2506|M.tuberculosis_H37Rv AEADARLMAHAVFGLLNSTPHSMKAADS---KPARTVRARAVLRAMTVAA
MUL_3464|M.ulcerans_Agy99 HDVDPHSEARSIQGVVWANTEQQWASGDCRRDEVRESTVRFCLRGLGVAP
MMAR_1569|M.marinum_M HDVDPHSEARSIQGVVWANTEQQWASGDCRRDEVRESTVRFCLRGLGVAP
MAV_2439|M.avium_104 HDVDPVTQAQFIHGVVWTGIARQWASGDCDRDDLRRRVQRFCLRGLGIAD
Mflv_2097|M.gilvum_PYR-GCK PLTEPEADAVAINAVVSRVLNTQTTDEPEARKKALVAVLDFALRAVGAAA
Mvan_4608|M.vanbaalenii_PYR-1 PLAEPEIDAVAVNALVSRLLVRQTTDDPQARKQAEVAVLDFALRAVGAVP
TH_2894|M.thermoresistible__bu PLTDPECDAVAIGAVVARALLEQTDLTDDEYRVGVECVMDFALRAIGADH
MSMEG_0343|M.smegmatis_MC2_155 DDTEARVIVHAAIGAIQSPLFHNTGLADDRLRVLLADSARSILSTDRRTP
MAB_0599|M.abscessus_ATCC_1997 PDLDVAVVYRFIRDATWVSVRWFRPGGSRTAQEVAEQYLSIVLGGITVGS
: *
Mb2534|M.bovis_AF2122/97 LSAADRCL-----
Rv2506|M.tuberculosis_H37Rv LSAADRCL-----
MUL_3464|M.ulcerans_Agy99 DTIAQITAPD---
MMAR_1569|M.marinum_M DTIAQITAPD---
MAV_2439|M.avium_104 EVIDRVCFVMERG
Mflv_2097|M.gilvum_PYR-GCK R------------
Mvan_4608|M.vanbaalenii_PYR-1 GGQDTRR------
TH_2894|M.thermoresistible__bu TPYRR--------
MSMEG_0343|M.smegmatis_MC2_155 -------------
MAB_0599|M.abscessus_ATCC_1997 FSNSPEK------