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RRAILDAASTTLRRQGVDGLSIAAVLSRASLSTRAFYRHFGSKDELVAAVFLEHARAEKRRLRRRMTGAA SEAEAVAAWIDGRLDLAFDDRIGNDLRRLSLEAQSQAMGPAELIQPAYAEMLEPLRDALQRGSQNGVFHD VDPVTQAQFIHGVVWTGIARQWASGDCDRDDLRRRVQRFCLRGLGIADEVIDRVCFVMERG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2439 | - | - | 100% (202) | transcriptional regulator, TetR family protein, putative |
| M. avium 104 | MAV_0309 | - | 5e-12 | 29.51% (183) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_1858 | - | 6e-10 | 30.12% (166) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0790c | - | 2e-06 | 25.99% (177) | hypothetical protein Mb0790c |
| M. gilvum PYR-GCK | Mflv_2097 | - | 3e-14 | 30.98% (184) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0767c | - | 2e-06 | 25.99% (177) | hypothetical protein Rv0767c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1589 | - | 3e-07 | 27.27% (165) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1569 | - | 7e-62 | 60.51% (195) | putative regulatory protein |
| M. smegmatis MC2 155 | MSMEG_6564 | - | 9e-08 | 29.77% (131) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2894 | - | 4e-18 | 33.33% (189) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_3464 | - | 3e-61 | 60.00% (195) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4608 | - | 3e-15 | 29.57% (186) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1569|M.marinum_M MSDIAATMKCRLRVSRKRLVGTYGSMTHPNNPGTRRQADLSSRLTRRRHK
MUL_3464|M.ulcerans_Agy99 MSDIAATMKCRLRVSRKRLVGTYGSMTHPNNPGTRRQADLSSRLTRRRHK
MAV_2439|M.avium_104 --------------------------------------------------
Mflv_2097|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4608|M.vanbaalenii_PYR-1 -----------------------------------------------MQP
TH_2894|M.thermoresistible__bu -----------------------------------------------VAT
Mb0790c|M.bovis_AF2122/97 --------------------------MSSDVLVTTPAQRQTEPHAEAVSR
Rv0767c|M.tuberculosis_H37Rv --------------------------MSSDVLVTTPAQRQTEPHAEAVSR
MAB_1589|M.abscessus_ATCC_1997 -----------------------------MTSHRERGARAGASSRRDSVR
MSMEG_6564|M.smegmatis_MC2_155 -------------------------------------------MTTAEAP
MMAR_1569|M.marinum_M LAPDPGIRRAILVAASMSVREHGVRGLSVATVLDRAQLSTRAFYRHFESK
MUL_3464|M.ulcerans_Agy99 LAPDPGIRRAILVAASMSVREHGVRGLSVATVLDRAQLSTRAFYRHFESK
MAV_2439|M.avium_104 ------MRRAILDAASTTLRRQGVDGLSIAAVLSRASLSTRAFYRHFGSK
Mflv_2097|M.gilvum_PYR-GCK -----------MEAAYRCLADPHAGPVSMAAILGTAGVSSRAFYRHFESK
Mvan_4608|M.vanbaalenii_PYR-1 GPDHDGDRRRIIEAAYRCLAQPHAGPIPMTSILRSAGLSSRAFYRHFLSK
TH_2894|M.thermoresistible__bu DSPASEDRKRIIDAAYQCLSERHVNPVSVAAILARAECSSRAFYRHFESK
Mb0790c|M.bovis_AF2122/97 NRRQQATFRKVLAAAMATLREKSYADLTVRLVAARAKVAPATAYTYFSSK
Rv0767c|M.tuberculosis_H37Rv NRRQQATFRKVLAAAMATLREKSYADLTVRLVAARAKVAPATAYTYFSSK
MAB_1589|M.abscessus_ATCC_1997 GEQKLRTRTALMEAALELSRTQAFSGLSLRDVARGAGISPTAFYRHFSSL
MSMEG_6564|M.smegmatis_MC2_155 RRRSEKSRVAIVEATRALLLERGFDGLSIEAVAAKAGVGKQTIYRWWPSR
: *: :.: : * . : * : *
MMAR_1569|M.marinum_M DQLVAAVFLEVARVEAVRLRTLMAKATN-PIEGVAAWIDGRLDLAFDDAV
MUL_3464|M.ulcerans_Agy99 DQLVAAMFLEVARVEAVRLRTLMAKATN-PIEGVAAWIDGRLDLAFDDAV
MAV_2439|M.avium_104 DELVAAVFLEHARAEKRRLRRRMTGAAS-EAEAVAAWIDGRLDLAFDDRI
Mflv_2097|M.gilvum_PYR-GCK DDLFLALLEQECSAVVGQVDRVADAAQGSPADQLAAWIEAMFDIVVDPRQ
Mvan_4608|M.vanbaalenii_PYR-1 DDLFLALLRQECEAVIAQVDRIADAAVGSPADQLADWIAAMFDIIVDPQQ
TH_2894|M.thermoresistible__bu DALFLAMVEEESAALTRRLDRIVAEHPGTPIEQLQAWVEQLFALVYDPAL
Mb0790c|M.bovis_AF2122/97 NHLIAEVYLD----LVRQVPCVTDVNVPMPIRVTSSLRHLALVVADEPEI
Rv0767c|M.tuberculosis_H37Rv NHLIAEVYLD----LVRQVPCVTDVNVPMPIRVTSSLRHLALVVADEPEI
MAB_1589|M.abscessus_ATCC_1997 DDLGVALAEEGMRIARGIAREIRRREPATLAESMRILAEQVQENP-----
MSMEG_6564|M.smegmatis_MC2_155 HALVADVLLEDADKILARMPKTDDVTAD-----LASWAGTLAAALTTRRG
. * : :
MMAR_1569|M.marinum_M KADLRHLSMDAQSHLLNTPELVEPAYAETLEPLIEQLHLGVAQEVFHDVD
MUL_3464|M.ulcerans_Agy99 KADLRHLSMGAQSHLLNAPELVEPAYAETLEPLIEQLHLGVAQEVFHDVD
MAV_2439|M.avium_104 GNDLRRLSLEAQSQAMGPAELIQPAYAEMLEPLRDALQRGSQNGVFHDVD
Mflv_2097|M.gilvum_PYR-GCK RLQLTVIDSEEVRTAKGYRQTRDRLHAARERGLAEILRRGLRDGSFPLTE
Mvan_4608|M.vanbaalenii_PYR-1 RLQLTVIDSDEVRAAKGYREMRERLHAERERSLAEILRRGRRDGSFPLAE
TH_2894|M.thermoresistible__bu REHMQVIDSDEVRSAKGFREVRERAHIERERSLRTILTRGRADGSMPLTD
Mb0790c|M.bovis_AF2122/97 GAACTAALLDGG-ADPAVRAVRDRIGAEIHRRITSAIGPGADPGTVFALE
Rv0767c|M.tuberculosis_H37Rv GAACTAALLDGG-ADPAVRAVRDRIGAEIHRRITSAIGPGADPGTVFALE
MAB_1589|M.abscessus_ATCC_1997 -DQLRFVVTERYTAPTEVRRAVNIEMRLLAGELAIDLARRDQMRLWDSAD
MSMEG_6564|M.smegmatis_MC2_155 HAMLKTLMAASLEHEDTAARLREGFSRPLIESVRDRLRD-------EDID
: : : :
MMAR_1569|M.marinum_M PHSEARSIQGVVWANTEQQWASGDCRRDEVRESTVRFCLRGLGVAPDTIA
MUL_3464|M.ulcerans_Agy99 PHSEARSIQGVVWANTEQQWASGDCRRDEVRESTVRFCLRGLGVAPDTIA
MAV_2439|M.avium_104 PVTQAQFIHGVVWTGIARQWASGDCDRDDLRRRVQRFCLRGLGIADEVID
Mflv_2097|M.gilvum_PYR-GCK PEADAVAINAVVSRVLNTQTTDEPEARKKALVAVLDFALRAVGAAAR---
Mvan_4608|M.vanbaalenii_PYR-1 PEIDAVAVNALVSRLLVRQTTDDPQARKQAEVAVLDFALRAVGAVPGGQD
TH_2894|M.thermoresistible__bu PECDAVAIGAVVARALLEQTDLTDDEYRVGVECVMDFALRAIGADHTPYR
Mb0790c|M.bovis_AF2122/97 MAFFGALVQAGSGTFTYHEIADR-------LGYVVGLILAGANEPSTGGS
Rv0767c|M.tuberculosis_H37Rv MAFFGALVQAGSGTFTYHEIADR-------LGYVVGLILAGANEPSTGGS
MAB_1589|M.abscessus_ATCC_1997 LTTAANLILSIAANAVAELVQPDTDTTEVVDSASNALTMAFVGLQNWKPA
MSMEG_6564|M.smegmatis_MC2_155 ADHAQAAADALLGAVVNAVLSEGRSYSRQRAETSARIIVAGLRP------
. : :
MMAR_1569|M.marinum_M QITAPD---
MUL_3464|M.ulcerans_Agy99 QITAPD---
MAV_2439|M.avium_104 RVCFVMERG
Mflv_2097|M.gilvum_PYR-GCK ---------
Mvan_4608|M.vanbaalenii_PYR-1 TRR------
TH_2894|M.thermoresistible__bu R--------
Mb0790c|M.bovis_AF2122/97 E--------
Rv0767c|M.tuberculosis_H37Rv E--------
MAB_1589|M.abscessus_ATCC_1997 QR-------
MSMEG_6564|M.smegmatis_MC2_155 ---------