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QPGPDHDGDRRRIIEAAYRCLAQPHAGPIPMTSILRSAGLSSRAFYRHFLSKDDLFLALLRQECEAVIAQ VDRIADAAVGSPADQLADWIAAMFDIIVDPQQRLQLTVIDSDEVRAAKGYREMRERLHAERERSLAEILR RGRRDGSFPLAEPEIDAVAVNALVSRLLVRQTTDDPQARKQAEVAVLDFALRAVGAVPGGQDTRR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4608 | - | - | 100% (206) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2744 | - | 5e-07 | 27.27% (176) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1492 | - | 5e-06 | 26.32% (171) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1510c | - | 2e-08 | 26.17% (149) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_2097 | - | 4e-79 | 78.69% (183) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1474c | - | 2e-08 | 26.17% (149) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_02568 | - | 5e-05 | 27.12% (177) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0647 | - | 2e-07 | 31.03% (87) | transcriptional regulator TetR |
| M. marinum M | MMAR_1569 | - | 2e-12 | 26.70% (191) | putative regulatory protein |
| M. avium 104 | MAV_1858 | - | 6e-18 | 35.15% (165) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0878 | - | 7e-09 | 27.84% (194) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_2894 | - | 7e-52 | 52.66% (188) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_3464 | - | 7e-12 | 26.18% (191) | putative regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4608|M.vanbaalenii_PYR-1 -----------------------------------------------MQP
Mflv_2097|M.gilvum_PYR-GCK --------------------------------------------------
TH_2894|M.thermoresistible__bu -----------------------------------------------VAT
MMAR_1569|M.marinum_M MSDIAATMKCRLRVSRKRLVGTYGSMTHPNNPGTRRQADLSSRLTRRRHK
MUL_3464|M.ulcerans_Agy99 MSDIAATMKCRLRVSRKRLVGTYGSMTHPNNPGTRRQADLSSRLTRRRHK
Mb1510c|M.bovis_AF2122/97 ---------------------------------------------MPKVS
Rv1474c|M.tuberculosis_H37Rv ---------------------------------------------MPKVS
MAB_0647|M.abscessus_ATCC_1997 ------------------------------------------MDQPARPL
MSMEG_0878|M.smegmatis_MC2_155 -----------------------------------------------MSM
MAV_1858|M.avium_104 ------------------------------------------------MS
MLBr_02568|M.leprae_Br4923 --------------------------------------------MAGGAK
Mvan_4608|M.vanbaalenii_PYR-1 GPDHDGDRRRIIEAAYRCLAQPHAGP-----IPMTSILRSAGLSSRAFYR
Mflv_2097|M.gilvum_PYR-GCK -----------MEAAYRCLADPHAGP-----VSMAAILGTAGVSSRAFYR
TH_2894|M.thermoresistible__bu DSPASEDRKRIIDAAYQCLSERHVNP-----VSVAAILARAECSSRAFYR
MMAR_1569|M.marinum_M LAPDPGIRRAILVAASMSVREHGVRG-----LSVATVLDRAQLSTRAFYR
MUL_3464|M.ulcerans_Agy99 LAPDPGIRRAILVAASMSVREHGVRG-----LSVATVLDRAQLSTRAFYR
Mb1510c|M.bovis_AF2122/97 EDHLAARRRQILDGARRCFAEYGYDK-----ATVRRLEQAIGMSRGAIFH
Rv1474c|M.tuberculosis_H37Rv EDHLAARRRQILDGARRCFAEYGYDK-----ATVRRLEQAIGMSRGAIFH
MAB_0647|M.abscessus_ATCC_1997 RADAARNRARVLEVAYQTFAEEGLG------VPIDEIARRAGVGAGTVYR
MSMEG_0878|M.smegmatis_MC2_155 RADAARNRARVLEVAYEAFAQDGLA------VPIDEIARRAGVGAGTVYR
MAV_1858|M.avium_104 DHRRPTERDAIMRAAYRLISEGAAGPSASSSTSIENILRVARVNRRVFYR
MLBr_02568|M.leprae_Br4923 RIPRAVREQQMLDAAVQMFSVNGYHK-----TSMDAIAAEAQISKPMLYL
: * . .: : . .:
Mvan_4608|M.vanbaalenii_PYR-1 HFLSKDDLFLALLRQECEAVIAQVDRIADAAVGSPADQLADWIAAMFDII
Mflv_2097|M.gilvum_PYR-GCK HFESKDDLFLALLEQECSAVVGQVDRVADAAQGSPADQLAAWIEAMFDIV
TH_2894|M.thermoresistible__bu HFESKDALFLAMVEEESAALTRRLDRIVAEHPGTPIEQLQAWVEQLFALV
MMAR_1569|M.marinum_M HFESKDQLVAAVFLEVARVEAVRLRTLMAKATN-PIEGVAAWIDGRLDLA
MUL_3464|M.ulcerans_Agy99 HFESKDQLVAAMFLEVARVEAVRLRTLMAKATN-PIEGVAAWIDGRLDLA
Mb1510c|M.bovis_AF2122/97 HFRDKDALFFALAREDT--------ERMAAVAS--REGLIGVMRDMLAAP
Rv1474c|M.tuberculosis_H37Rv HFRDKDALFFALAREDT--------ERMAAVAS--REGLIGVMRDMLAAP
MAB_0647|M.abscessus_ATCC_1997 HFPAKEDLYRAIAEDRMGSVIDKGRELLAAVDP--GEALFEFLRSM----
MSMEG_0878|M.smegmatis_MC2_155 HFPSKEDLYRAVVAERIREIVDQGQALLADGDP--GEALFDYLRLMV---
MAV_1858|M.avium_104 HFASKDDLIIAMQEWAGDLILADLQKAVAAADT-PAAAVAAWIEDYLSIG
MLBr_02568|M.leprae_Br4923 YYGSKEDLFGACLNREMSRFIAMVRADIDFTQS-PKDLLRNTIVSFLR--
:: *: * * : :
Mvan_4608|M.vanbaalenii_PYR-1 VDPQQRLQLTVIDSDEVRAAKGYREMRERLHAERERSLAEILRRGRRDGS
Mflv_2097|M.gilvum_PYR-GCK VDPRQRLQLTVIDSEEVRTAKGYRQTRDRLHAARERGLAEILRRGLRDGS
TH_2894|M.thermoresistible__bu YDPALREHMQVIDSDEVRSAKGFREVRERAHIERERSLRTILTRGRADGS
MMAR_1569|M.marinum_M FDDAVKADLRHLSMDAQSHLLNTPELVEPAYAETLEPLIEQLHLGVAQEV
MUL_3464|M.ulcerans_Agy99 FDDAVKADLRHLSMGAQSHLLNAPELVEPAYAETLEPLIEQLHLGVAQEV
Mb1510c|M.bovis_AF2122/97 DQFDWLATRLEIARKLRND-PDFSRGWAERSAELAAATTDRLRRQKQANR
Rv1474c|M.tuberculosis_H37Rv DQFDWLATRLEIARKLRND-PDFSRGWAERSAELAAATTDRLRRQKQANR
MAB_0647|M.abscessus_ATCC_1997 --MDWGGTDQGLVDALSGAGIDVQALIPHIEESFYAVLGDLLRAAQQAGT
MSMEG_0878|M.smegmatis_MC2_155 --LQCGAADRGLVEALAGAGIDVKTMVPDAEDEYMEMLGGLLRAAQRAGT
MAV_1858|M.avium_104 WQEARFRDALAFMSAEVIGAPGIAAALEVTYDRHRAVLTEALAAGLADGS
MLBr_02568|M.leprae_Br4923 -YIDANRASWIVMYIQAMSLPAFAQTVREARDQITELVAGLMRVGTRSSR
. :
Mvan_4608|M.vanbaalenii_PYR-1 FPLAEPEIDAVAVNALVSRLLVRQTTD-DPQARKQAEVAVLDFALRAVGA
Mflv_2097|M.gilvum_PYR-GCK FPLTEPEADAVAINAVVSRVLNTQTTD-EPEARKKALVAVLDFALRAVGA
TH_2894|M.thermoresistible__bu MPLTDPECDAVAIGAVVARALLEQTDL-TDDEYRVGVECVMDFALRAIGA
MMAR_1569|M.marinum_M FHDVDPHSEARSIQGVVWANTEQQWAS-GDCRRDEVRESTVRFCLRGLGV
MUL_3464|M.ulcerans_Agy99 FHDVDPHSEARSIQGVVWANTEQQWAS-GDCRRDEVRESTVRFCLRGLGV
Mb1510c|M.bovis_AF2122/97 VRDDVPSDVLRCYLDLVLDGLLARLAS-GEDPQR--LAAVLDLVENSVRR
Rv1474c|M.tuberculosis_H37Rv VRDDVPSDVLRCYLDLVLDGLLARLAS-GEDPQR--LAAVLDLVENSVRR
MAB_0647|M.abscessus_ATCC_1997 VRSDVGVHEVKALLVGCQA--MQSYNK-DVSRQV--TDVVFDGLRPRP--
MSMEG_0878|M.smegmatis_MC2_155 VRGDVTATDVKALLVGCQA--MQAYDA-TAAEHL--TGVVFDGLRVAPAS
MAV_1858|M.avium_104 LPNAHPELDSFAIHAVTVRHLEARIRGRLDSDFREVRDQIVTLMLTGLSA
MLBr_02568|M.leprae_Br4923 PDHEYEIMAGALVGAGEAMATRLTTGDIAVDEAAELMINLFWHGLKGAPA
.
Mvan_4608|M.vanbaalenii_PYR-1 VPGGQDTRR---
Mflv_2097|M.gilvum_PYR-GCK AAR---------
TH_2894|M.thermoresistible__bu DHTPYRR-----
MMAR_1569|M.marinum_M APDTIAQITAPD
MUL_3464|M.ulcerans_Agy99 APDTIAQITAPD
Mb1510c|M.bovis_AF2122/97 S-----------
Rv1474c|M.tuberculosis_H37Rv S-----------
MAB_0647|M.abscessus_ATCC_1997 ------------
MSMEG_0878|M.smegmatis_MC2_155 VPSR--------
MAV_1858|M.avium_104 PAVYRTATR---
MLBr_02568|M.leprae_Br4923 DRDFGPSIVAG-