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AGLRRKLLLEAAADLFARQGFHAVGIDDIGAAAGVSGPAVYRHFQNKDAILRELCDAAMTELLAGARRAT TAGTPTEVLHALVDLHAAFGARRRGLLAVYAREHRSLSPLATRALRRRQHSYESFWVEALVRARGDLDRE RAQGLVAAVLSLLNASAYMPASLDDATIEAMLAAAAVAALFSRAVTQQVDGAPHRI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2061c | - | - | 100% (197) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4541 | - | 2e-26 | 37.22% (180) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4912c | - | 2e-13 | 31.50% (127) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2534 | - | 4e-26 | 37.50% (184) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2551 | - | 2e-26 | 39.67% (184) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2506 | - | 4e-26 | 37.50% (184) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 8e-10 | 27.15% (151) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_3853 | - | 2e-26 | 37.97% (187) | putative regulatory protein |
| M. avium 104 | MAV_1669 | - | 2e-25 | 38.71% (186) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_4718 | - | 2e-28 | 40.88% (181) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4549 | - | 2e-11 | 29.94% (177) | PUTATIVE putative TetR-family protein transcriptional regulator |
| M. ulcerans Agy99 | MUL_3785 | - | 1e-26 | 37.97% (187) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4092 | - | 1e-24 | 38.92% (185) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2534|M.bovis_AF2122/97 ------------MTASAPDGRPGQPEATNRRSQ--LKSDRRFQLLAAAER
Rv2506|M.tuberculosis_H37Rv ------------MTASAPDGRPGQPEATNRRSQ--LKSDRRFQLLAAAER
MAV_1669|M.avium_104 -----------------------------------MKSDRRLQLLSAAER
MMAR_3853|M.marinum_M ------------MAASAPDEQTATP---NRRSQ--QKSDRRLQLLSAAER
MUL_3785|M.ulcerans_Agy99 ------------MAASAPDEQTATP---NRRSQ--QKSDRRLQLLSAAER
Mflv_2551|M.gilvum_PYR-GCK ------------MAPTEI---------SSPRSR--AKSDRRDQLVAAAER
Mvan_4092|M.vanbaalenii_PYR-1 ------------MTTTDA---------TSPRSR--AKSDRRGQLIGAAER
MSMEG_4718|M.smegmatis_MC2_155 ------------MSS------------VTRRSQ--AKSDRRSQLIAAAER
MAB_2061c|M.abscessus_ATCC_199 -----------------------------------MAGLRRKLLLEAAAD
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
TH_4549|M.thermoresistible__bu ---------------------------VDGLTE--QQREQRERILRAAAE
:* :: .*
Mb2534|M.bovis_AF2122/97 LFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVSARLLA
Rv2506|M.tuberculosis_H37Rv LFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVSARLLA
MAV_1669|M.avium_104 LFAERGFLAVRLEDIGASAGVSGPAIYRHFPNKESLLVELLVGISTRLLA
MMAR_3853|M.marinum_M LFAERGFLAVRLEDIGAAAGISGPAIYRHFPNKESLLVELLVGISSRLLA
MUL_3785|M.ulcerans_Agy99 LFAERGFLAVRLEDIGAAAGISGPAIYRHFPNKESLLVELLVGISSRLLA
Mflv_2551|M.gilvum_PYR-GCK LFAEHGYLAVRLEDIGSAAGISGPAVYRHFPNKEALLVELLVGISTRLLA
Mvan_4092|M.vanbaalenii_PYR-1 LIAEHGYLAVRLEDIGAAAGISGPAIYRHFPNKEALLVELLVGISTRLLA
MSMEG_4718|M.smegmatis_MC2_155 LVAERGYLAVRLEDIGAAVGVSGPAIYRHFPNKEAMLVELLVGISTRLLD
MAB_2061c|M.abscessus_ATCC_199 LFARQGFHAVGIDDIGAAAGVSGPAVYRHFQNKDAILRELCDAAMTELLA
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
TH_4549|M.thermoresistible__bu ILAEQGRDAVTTRNVSAAAGVQPPTIYRHFGDMRRLIDDAASLGMAEYLK
:.. :* *. ::. .*:. *.:*:** . : . :
Mb2534|M.bovis_AF2122/97 GARDVTT-RSANLAAALDGLIEFHLDFALGEADLIRIQDRD---------
Rv2506|M.tuberculosis_H37Rv GARDVTT-RSANLAAALDGLIEFHLDFALGEADLIRIQDRD---------
MAV_1669|M.avium_104 GARQVRA-RSADAAAALDGLIDFHLDFALNEPDLIRIQDRD---------
MMAR_3853|M.marinum_M GARQVTT-NSNDAAAALDGLIDFHLDFALGEPDLIRIQDRD---------
MUL_3785|M.ulcerans_Agy99 GARQVTT-NSNDAAAALDGLIDFHLDFALGEPDLIRIQDRD---------
Mflv_2551|M.gilvum_PYR-GCK GATDVVG-ADDDAASTLENLIDFHLDFALDESDLIRIQDRD---------
Mvan_4092|M.vanbaalenii_PYR-1 GAVEVVDRAGDDADSALEGLIDFHLDFVFGEPDLIRIQDRD---------
MSMEG_4718|M.smegmatis_MC2_155 GAREVVE-THDDPAKALDALVDFHLDFAFDESDLIRIQDRD---------
MAB_2061c|M.abscessus_ATCC_199 GARRATT--AGTPTEVLHALVDLHAAFGARRRGLLAVYARE---------
MLBr_00815|M.leprae_Br4923 SVQQALR-TTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFEN---------
TH_4549|M.thermoresistible__bu AKRERAL--TDDPVHDLRDGWDLHVEFGLRHPATYTVLYGDPRPDAKPRA
. * : . * : :
Mb2534|M.bovis_AF2122/97 -----------------LAHLPAVAERQVRKAQRQYVEVWVGVLRELNPG
Rv2506|M.tuberculosis_H37Rv -----------------LAHLPAVAERQVRKAQRQYVEVWVGVLRELNPG
MAV_1669|M.avium_104 -----------------LAYLPKPAERQVRKAQRQYVEVWVGVLRELNPE
MMAR_3853|M.marinum_M -----------------LGHLPAAAERQVRKAQRQYVEIWVGVLRQLDPG
MUL_3785|M.ulcerans_Agy99 -----------------LGHLPAAAERQVRKAQRQYVEIWVGVLRQLDPG
Mflv_2551|M.gilvum_PYR-GCK -----------------LGNLPPAAKRQVRRKQRQYVEIWVDVLRRCTPG
Mvan_4092|M.vanbaalenii_PYR-1 -----------------LGNLPPAAKRQVRRKQRQYVEIWVDVLRRRTPG
MSMEG_4718|M.smegmatis_MC2_155 -----------------LAHLPDTAKRQVRRAQRQYVEIWVSVLTRLRRD
MAB_2061c|M.abscessus_ATCC_199 -----------------HRSLSPLATRALRRRQHSYESFWVEALVRARGD
MLBr_00815|M.leprae_Br4923 -----------------DNITEPRVAAQVRVATESCIDAVFALIS-ADSR
TH_4549|M.thermoresistible__bu VAEGDAILRSLMQRVAEAGRLRIGVDRAAEMMHSACRGVTLTLISQTPAE
. . . :
Mb2534|M.bovis_AF2122/97 LAEADARLMAHAVFGLLNSTPHSMKAADS---KPARTVRARAVLRAMTVA
Rv2506|M.tuberculosis_H37Rv LAEADARLMAHAVFGLLNSTPHSMKAADS---KPARTVRARAVLRAMTVA
MAV_1669|M.avium_104 LAEADARLTAHAVFGLLNSTPHSMKSQDSGRGKPARAARSRAIMRAMTVA
MMAR_3853|M.marinum_M LAEADARLMAHAAFGLLNSTPHSMKSADT---KSACAPHSRAVMRAMTVA
MUL_3785|M.ulcerans_Agy99 LAEADARLMAHAAFGLLNSTPHSMESADT---KSACAPHSRAVMRAMTVA
Mflv_2551|M.gilvum_PYR-GCK LSEADARLMAHGTFGLLNSTAHSMKPGTT--KT--AEAGSRTVLREMTVA
Mvan_4092|M.vanbaalenii_PYR-1 LTETDARLMAHAAFGLLNSTPHGVKPGLN--KA--AEASSRTVLRTMTVA
MSMEG_4718|M.smegmatis_MC2_155 LPEEEARVMAHATFGLLNSTPHSVKPAVT--KAQSSTAQSRGVLRRMTVA
MAB_2061c|M.abscessus_ATCC_199 LDRERAQGLVAAVLSLLNASAYMPASLDDATIEAMLAAAAVAALFSRAVT
MLBr_00815|M.leprae_Br4923 LDPHRARMVAVGLVGISVDCARYWLDTNR----PISKSDAVEGTVQFAWG
TH_4549|M.thermoresistible__bu RDPELSAATREAMLAAITTGGAAGPADGAG--VATRAIALKSVLETGGAG
: . ..
Mb2534|M.bovis_AF2122/97 ALSAADRCL----------
Rv2506|M.tuberculosis_H37Rv ALSAADRCL----------
MAV_1669|M.avium_104 ALAAGNQCP----------
MMAR_3853|M.marinum_M ALTVDVGA-----------
MUL_3785|M.ulcerans_Agy99 ALTVDVGA-----------
Mflv_2551|M.gilvum_PYR-GCK ALTSAERRRG---------
Mvan_4092|M.vanbaalenii_PYR-1 ALTSAGRRA----------
MSMEG_4718|M.smegmatis_MC2_155 ALTATG-------------
MAB_2061c|M.abscessus_ATCC_199 QQVDGAPHRI---------
MLBr_00815|M.leprae_Br4923 GLSHVPLTRL---------
TH_4549|M.thermoresistible__bu VLTEAEAELLKEWLDRLSQ