For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_1621 | - | - | 100% (264) | dehydrogenase |
| M. thermoresistible (build 8) | TH_2445 | - | 1e-29 | 41.49% (188) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. thermoresistible (build 8) | TH_3693 | - | 1e-22 | 33.16% (193) | PUTATIVE short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2882c | - | 2e-26 | 35.94% (192) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1267 | - | 1e-107 | 72.20% (259) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2857c | - | 3e-26 | 35.94% (192) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_00862 | ephD | 2e-18 | 33.33% (210) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4023c | - | 2e-23 | 37.70% (191) | oxidoreductase |
| M. marinum M | MMAR_2849 | - | 2e-25 | 38.66% (194) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_3714 | - | 2e-27 | 35.15% (239) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_6623 | - | 1e-106 | 73.08% (260) | dehydrogenase |
| M. ulcerans Agy99 | MUL_0336 | - | 1e-23 | 36.46% (192) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_4644 | - | 5e-30 | 41.24% (194) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1267|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6623|M.smegmatis_MC2_155 --------------------------------------------------
TH_1621|M.thermoresistible__bu --------------------------------------------------
MMAR_2849|M.marinum_M --------------------------------------------------
MUL_0336|M.ulcerans_Agy99 --------------------------------------------------
Mb2882c|M.bovis_AF2122/97 --------------------------------------------------
Rv2857c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3714|M.avium_104 --------------------------------------------------
MLBr_00862|M.leprae_Br4923 MPATQSIHKVPHQFVESPDGVRLAIYQSGQPEGPAIVLVHGFPDSHVLWD
MAB_4023c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_4644|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1267|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6623|M.smegmatis_MC2_155 --------------------------------------------------
TH_1621|M.thermoresistible__bu --------------------------------------------------
MMAR_2849|M.marinum_M --------------------------------------------------
MUL_0336|M.ulcerans_Agy99 --------------------------------------------------
Mb2882c|M.bovis_AF2122/97 --------------------------------------------------
Rv2857c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3714|M.avium_104 --------------------------------------------------
MLBr_00862|M.leprae_Br4923 GVVPLLAKRFRIVRYDNRGVGQSSVPKPVSAYTMTRFADDFAAVIDELSP
MAB_4023c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_4644|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1267|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6623|M.smegmatis_MC2_155 --------------------------------------------------
TH_1621|M.thermoresistible__bu --------------------------------------------------
MMAR_2849|M.marinum_M --------------------------------------------------
MUL_0336|M.ulcerans_Agy99 --------------------------------------------------
Mb2882c|M.bovis_AF2122/97 --------------------------------------------------
Rv2857c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3714|M.avium_104 --------------------------------------------------
MLBr_00862|M.leprae_Br4923 DRPVHVLAHDWGSVGVWEYLSRSGASDRVASFTSVSGPSQDQLVDYILSG
MAB_4023c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_4644|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1267|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6623|M.smegmatis_MC2_155 --------------------------------------------------
TH_1621|M.thermoresistible__bu --------------------------------------------------
MMAR_2849|M.marinum_M --------------------------------------------------
MUL_0336|M.ulcerans_Agy99 --------------------------------------------------
Mb2882c|M.bovis_AF2122/97 --------------------------------------------------
Rv2857c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3714|M.avium_104 --------------------------------------------------
MLBr_00862|M.leprae_Br4923 LRRPWRPRTFARAVSQLFRLTYMVLFSIPVLVPMVLWIALSSATIRRTMV
MAB_4023c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_4644|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1267|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6623|M.smegmatis_MC2_155 --------------------------------------------------
TH_1621|M.thermoresistible__bu --------------------------------------------------
MMAR_2849|M.marinum_M --------------------------------------------------
MUL_0336|M.ulcerans_Agy99 --------------------------------------------------
Mb2882c|M.bovis_AF2122/97 --------------------------------------------------
Rv2857c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3714|M.avium_104 --------------------------------------------------
MLBr_00862|M.leprae_Br4923 DNISTDQIHHSATLARDAAHSVKTYPANYFRAFSGRRRGKGVPVVNVPVQ
MAB_4023c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_4644|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1267|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6623|M.smegmatis_MC2_155 --------------------------------------------------
TH_1621|M.thermoresistible__bu --------------------------------------------------
MMAR_2849|M.marinum_M --------------------------------------------------
MUL_0336|M.ulcerans_Agy99 --------------------------------------------------
Mb2882c|M.bovis_AF2122/97 --------------------------------------------------
Rv2857c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3714|M.avium_104 --------------------------------------------------
MLBr_00862|M.leprae_Br4923 LIVNTMDRYVRPYGYDATARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHD
MAB_4023c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_4644|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1267|M.gilvum_PYR-GCK -----------------------MNLAGRVALVTGGASGIGRATAVRLAA
MSMEG_6623|M.smegmatis_MC2_155 -----------------------MELQDRVALVTGGGSGIGRAAAQRLAA
TH_1621|M.thermoresistible__bu -----------------------VRLDGRAALVTGGGSGIGKATAQRLAA
MMAR_2849|M.marinum_M -----------------MSVLDLFDLSGKRALITGASTGIGKKVALAYAE
MUL_0336|M.ulcerans_Agy99 ---------------------MVDELAGKIAIVTGGASGIGRATVARFIA
Mb2882c|M.bovis_AF2122/97 ------------------MMDLSQRLAGRVAVITGGGSGIGLAAGRRMRA
Rv2857c|M.tuberculosis_H37Rv ------------------MMDLSQRLAGRVAVITGGGSGIGLAAGRRMRA
MAV_3714|M.avium_104 ------------------MMDLTQRLAGRVAVITGAGGGIGLAAARRMHA
MLBr_00862|M.leprae_Br4923 LADLVDGKQPSRALLRAQVGRSRDTFGDTLVSVTGAGSGIGRETALALAR
MAB_4023c|M.abscessus_ATCC_199 --------------MRVNPSEPR------LVVVTGAGSGIGRATAIRFAK
Mvan_4644|M.vanbaalenii_PYR-1 --------------MRFTG---------KHAIITGGGSGIGAALCRALDR
. :**.. ***
Mflv_1267|M.gilvum_PYR-GCK EGMQVCVVDIDGSAAEEVAESFGG-----IGLRCDVTDPDQVDATFAACA
MSMEG_6623|M.smegmatis_MC2_155 HGMRVCVVDIDGDAAREVAEPLGG-----LALTCDVSDPDQVNVTFDRCA
TH_1621|M.thermoresistible__bu AGMRVCVADIDADAAAEVADTVNG-----VAVRCDVSDPAQVDRVFAACT
MMAR_2849|M.marinum_M AGAQVAVAARHSDALQVVADEIAGVGGKALPIRCDVTQPDQVRGMLDQMT
MUL_0336|M.ulcerans_Agy99 EGARVVIADVEEERGESLAAALG---ADAMFCRTDVSQPEQVAAVVAAAV
Mb2882c|M.bovis_AF2122/97 EGATIVVGDVDVEAGGAAADELSG-----LFVPTDVCDEDAVNGLFDGAA
Rv2857c|M.tuberculosis_H37Rv EGATIVVGDVDVEAGGAAADELSG-----LFVPTDVCDEDAVNGLFDGAA
MAV_3714|M.avium_104 EGATIVVADIDADAGAAAADELSG-----LFVPTDVADEDAVNALFDTAV
MLBr_00862|M.leprae_Br4923 RGAEVVVSDIDEAAAKNTAAQIVASGGVAYAYALDVSDAAAVEAFAEQVS
MAB_4023c|M.abscessus_ATCC_199 RGAHVVVTDLDLDTANETVDLILAMGRNASAVQLDVTDPAHWADVARYVS
Mvan_4644|M.vanbaalenii_PYR-1 AGAQVVCTDIDEAAAGAVVSTLSPR---ARAARLDVTDAAAVQGVVDDVV
* : . . . ** :
Mflv_1267|M.gilvum_PYR-GCK AGFGRLDLAFLNAGVTIDWSGDIGSLDVAQYRRSVGVNVDGVVFGVRAAV
MSMEG_6623|M.smegmatis_MC2_155 TELGGVDVAFLNAGITIAWSGDIGALDLTDYRRSVGVNLDGVVYGVVAAV
TH_1621|M.thermoresistible__bu HELGGVDLAFLNAGITIEWSGDIAELDLAQYRRSVGVNLDGVVFGARAAV
MMAR_2849|M.marinum_M GELGGIDIAVCNAGIVSVQA--MLDMPLEEFQRIQDTNVTGVFLTAQAAA
MUL_0336|M.ulcerans_Agy99 DNFGGLHVMVNNAGVSGAMHRRFLDDDLADFHRVMAVNVLGVMAGTRDAA
Mb2882c|M.bovis_AF2122/97 ETYGRIDIAFNNAGISPPEDNLIENTELAAWQRVQDVNLKSVYLCCRAAL
Rv2857c|M.tuberculosis_H37Rv ETYGRIDIAFNNAGISPPEDNLIENTELAAWQRVQDVNLKSVYLCCRAAL
MAV_3714|M.avium_104 RRYGRIDIAFNNAGISPPDDDVIENTEPPAWQRVQDVNLKSVYLCCRAAL
MLBr_00862|M.leprae_Br4923 AKHGVPDIVVNNAGIG--QAGRFLDTPPEEFDRVLAVNLGGVVNCCRAFG
MAB_4023c|M.abscessus_ATCC_199 IEYGVPDVLVNNAGIA--LGGPFLKLTPADWDRLLSVNLMGVVHGCRVFG
Mvan_4644|M.vanbaalenii_PYR-1 ARTGRLDLIFNNAGIV--WGGDTELLTLDQWNAIIDINLRGVVHGVAAAY
* .: . ***: : *: .*
Mflv_1267|M.gilvum_PYR-GCK RTMRSLGAGTDRAILATASLAGLMPWHPDPVYSLGKHGVVGFMRSVAPNL
MSMEG_6623|M.smegmatis_MC2_155 RTMRSR-PGADRAILATASLAGILPWHPDPVYSLGKHGVVGLMRSVAPNL
TH_1621|M.thermoresistible__bu RSMRVRTRRSHGVILATASLAGLIPWHPDPVYSLGKHAVVGFMRSIAPNL
MMAR_2849|M.marinum_M RAMVDQGLGGTIITTASMSGHIINIPQQVSHYCTSKAAVVHLTKAMAVEL
MUL_0336|M.ulcerans_Agy99 RHMAAHG-GGSIVNLTSIGG--IQAGGGVMTYRASKGAVIQFTKSAAIEL
Mb2882c|M.bovis_AF2122/97 RHMVLAG-KGSIVNTASFVAVMGSATSQIS-YTASKGGVLAMSRELGVQF
Rv2857c|M.tuberculosis_H37Rv RHMVLAG-KGSIVNTASFVAVMGSATSQIS-YTASKGGVLAMSRELGVQF
MAV_3714|M.avium_104 RHMVSAR-RGSIINTASFVAVMGSATSQIS-YTAAKGGVLALSRELGVQF
MLBr_00862|M.leprae_Br4923 QRLVERGTGGHIVNVSSMAA--YAPLQSLSAYCTSKAATYMFSDCLRAEL
MAB_4023c|M.abscessus_ATCC_199 EQMVERGSG-HIVNIASAAA--FTPTAVMAPYSVSKAGVKMLTECLRLEL
Mvan_4644|M.vanbaalenii_PYR-1 PQMLRQGHG-HIVNTASMAG--LTAAGQVTSYVATKHAVVGLSMALRSEA
: :: * * .. : :
Mflv_1267|M.gilvum_PYR-GCK AAESIAVHTICPGITETGVLGDRRPLVERIG--------VPVMEPDAIAE
MSMEG_6623|M.smegmatis_MC2_155 AAEGIAVHTICPGITETGVLGDRRPLVERIG--------VPVMEPEAIAD
TH_1621|M.thermoresistible__bu APEGIAVHTICPGITETGVLGDRRPLVERIG--------VPVMEADTVSD
MMAR_2849|M.marinum_M APHQIRVNSVSPGYIRTELVEP-----------------LADYHALWEPK
MUL_0336|M.ulcerans_Agy99 AHYEIRVNAIAPGNIPTPLLASSAAGLDQEQV----ERFTAQIRQTMRED
Mb2882c|M.bovis_AF2122/97 ARQGIRVNALCPGPVNTPLLQELFAK-------------NPERAARRMVH
Rv2857c|M.tuberculosis_H37Rv ARQGIRVNALCPGPVNTPLLQELFAK-------------NPERAARRMVH
MAV_3714|M.avium_104 ARQGIRVNALCPGPVNTPLLQELFAK-------------DPQRAARRLVH
MLBr_00862|M.leprae_Br4923 DAVGVGLTTICPGVIDTNI-IQSTRIDTP----TAKQERVRDRRGQLDMM
MAB_4023c|M.abscessus_ATCC_199 GPKGVGVSAICPGFINTNIGVHGTMVGVDPEIADASQRRIQRIR-EFTEK
Mvan_4644|M.vanbaalenii_PYR-1 VPRGVGVLVVCPAAVETPILDKGAVGGFVG-------------RDYFLQT
: : :.*. * :
Mflv_1267|M.gilvum_PYR-GCK AVMVALDAPADATGTCWVAQYGKPAWPMVFAPVESPDSRLNVPVRLR---
MSMEG_6623|M.smegmatis_MC2_155 AVMAAVAAPLADTGACWVVQHGKAPTPMRFADVDCPDARLNVPVRR----
TH_1621|M.thermoresistible__bu AVLAAARAPIGQTGACWVTQHGKPAWPMTFPDVPGPDSKLNVPVRRTSG-
MMAR_2849|M.marinum_M IPLGRMGRPEELTGLYLYLASAASSYMTGSDIVIDGGYTCP---------
MUL_0336|M.ulcerans_Agy99 RPLKREGTPEDIAEAALYFAGERSRYVTGTVLPVDGGTVAGKVIRRSR--
Mb2882c|M.bovis_AF2122/97 VPLGRFAEPDEIAAAVAFLASDDASFITASTFLVDGGISSAYVTPL----
Rv2857c|M.tuberculosis_H37Rv VPLGRFAEPDEIAAAVAFLASDDASFITASTFLVDGGISSAYVTPL----
MAV_3714|M.avium_104 VPVGRFAEPGEIAAAAAFLASDDASFITASTFLVDGGISAAYVTPL----
MLBr_00862|M.leprae_Br4923 FRLRRYGPDKVADTILSAIKKNKPIRPVAPEAYALYGISRVLPQVLR---
MAB_4023c|M.abscessus_ATCC_199 LPWTPMSPELVARAVTRAIRLDLVVVPVKLESWFGYFVSRALPAVNRRLM
Mvan_4644|M.vanbaalenii_PYR-1 QGGRAYDADRLARDTLRAVERNKAILVKPTVAQAQWWFARLAPGLMNRMA
Mflv_1267|M.gilvum_PYR-GCK --------------------------------
MSMEG_6623|M.smegmatis_MC2_155 --------------------------------
TH_1621|M.thermoresistible__bu --------------------------------
MMAR_2849|M.marinum_M --------------------------------
MUL_0336|M.ulcerans_Agy99 --------------------------------
Mb2882c|M.bovis_AF2122/97 --------------------------------
Rv2857c|M.tuberculosis_H37Rv --------------------------------
MAV_3714|M.avium_104 --------------------------------
MLBr_00862|M.leprae_Br4923 ---STARIRVI---------------------
MAB_4023c|M.abscessus_ATCC_199 APFGVDRFERLGARALVKQQEHYVPALVESVG
Mvan_4644|M.vanbaalenii_PYR-1 MRFVTGQRTRQVDRYPSSAADTG---------