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M. thermoresistible (build 8) TH_1335 (-)

annotation: oxidoreductase, short chain dehydrogenase/reductase family protein
coordinates: 2540465 - 2540986
length: 174

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1335--100% (174)oxidoreductase, short chain dehydrogenase/reductase family protein
M. thermoresistible (build 8)TH_3505-2e-2744.97% (149) PUTATIVE short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_3954-4e-2143.33% (120) PUTATIVE 3-oxoacyl-[acyl-carrier-protein] reductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1963c-2e-2139.16% (143) short chain dehydrogenase
M. gilvum PYR-GCKMflv_1787-2e-7984.71% (170) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37RvRv1928c-2e-2139.16% (143) short chain dehydrogenase
M. leprae Br4923MLBr_01807fabG17e-1531.06% (132) 3-oxoacyl-
M. abscessus ATCC 19977MAB_4680c-3e-1938.30% (141) putative short-chain dehydrogenase/reductase
M. marinum MMMAR_0306-2e-7277.97% (177) short-chain type dehydrogenase/reductase
M. avium 104MAV_5208-3e-7682.66% (173) oxidoreductase, short chain dehydrogenase/reductase family
M. smegmatis MC2 155MSMEG_5628-8e-7681.98% (172) oxidoreductase, short chain dehydrogenase/reductase family
M. ulcerans Agy99MUL_0327-1e-2442.14% (140) oxidoreductase
M. vanbaalenii PYR-1Mvan_4963-8e-7883.24% (173) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


Mb1963c|M.bovis_AF2122/97           ----------MSVLDLFDLHGKRALITGAS-TGIGKRVALAYVEAGAQVA
Rv1928c|M.tuberculosis_H37Rv        ----------MSVLDLFDLHGKRALITGAS-TGIGKRVALAYVEAGAQVA
Mflv_1787|M.gilvum_PYR-GCK          ---------MT-TGVSINLDGRIVVVSGAGGGGIGTTVTRLAADAGATVV
Mvan_4963|M.vanbaalenii_PYR-1       ---------MSGTGISIRLDRRIVVVSGAGGGGIGTTVTRLAAEAGATVV
MSMEG_5628|M.smegmatis_MC2_155      ------------MDKLLNLDGRIVVVSGAGGGGIGTTVTRMAAEAGATVV
TH_1335|M.thermoresistible__bu      --------------------------------------------------
MAV_5208|M.avium_104                ----------------------MVVVSGAGGGGIGTTVTAMAARAGATVI
MMAR_0306|M.marinum_M               -----------MTVDLLSLSGRVVVVAGAAGGGIGTAVTRMVARAGATVV
MUL_0327|M.ulcerans_Agy99           ---------MAIDPADVLLNGRVAVVTGAG-SGIGRGVAAGLAAFGASMA
MLBr_01807|M.leprae_Br4923          MTDAAAKVSAAPGRGKPAFVSRSILVTGGN-RGIGLAVARRLVADGHRVA
MAB_4680c|M.abscessus_ATCC_199      -----------MNGNSALLQGKNVIVTGGA-RGLGAAFSRHIVSQGGRVV
                                                                                      

Mb1963c|M.bovis_AF2122/97           IAARHLDALEKLADEIGTSGGKVVPVCCDVSQHQQVTSMLDQVTAELGGI
Rv1928c|M.tuberculosis_H37Rv        IAARHLDALEKLADEIGTSGGKVVPVCCDVSQHQQVTSMLDQVTAELGGI
Mflv_1787|M.gilvum_PYR-GCK          AVSRSQDNLDEHVVPLAGEGRDVVTVAADASTDDGIATVLDTVRRTPGRL
Mvan_4963|M.vanbaalenii_PYR-1       AVSRSKDNLDEHVVPLARKGLSVVPVAADASTDDGIATVLDHVRRTDGDL
MSMEG_5628|M.smegmatis_MC2_155      AVSRSQDNLDTHVGPLADKGLSVVTVAADASTDDGIATVLDAVRRTDGRL
TH_1335|M.thermoresistible__bu      --------------------------------------------------
MAV_5208|M.avium_104                AVSRSKENLDEHIAPLAAQGLAVLPVAADASTDEGIAAVIDQARRADGQL
MMAR_0306|M.marinum_M               AVSRGQDNLDRQVGPLVAEGLAVLPVAADVCTDEGIEATLEAVRRADGDL
MUL_0327|M.ulcerans_Agy99           IWERDPQTCAQAAAELGGLG-----IATDVRSGDQVDAALQRTQAELGAV
MLBr_01807|M.leprae_Br4923          VT--------HRASVVPDWFFG---VECDVTDNDAIGAAFKAVEEHQGPV
MAB_4680c|M.abscessus_ATCC_199      IADVLDGDGRQLAAELGDAARF---THLDVTDAEQWRELIDTTLAGFGTI
                                                                                      

Mb1963c|M.bovis_AF2122/97           DIAVCNAG---IITVTPMLDMPLEEFQRLQNTNVTGVFLTAQAAAKAMVK
Rv1928c|M.tuberculosis_H37Rv        DIAVCNAG---IITVTPMLDMPLEEFQRLQNTNVTGVFLTAQAAAKAMVK
Mflv_1787|M.gilvum_PYR-GCK          YGLVNIAGGAAPATWMPSTRVTRDDWRALFQANLETAFFMSQAISGEIRS
Mvan_4963|M.vanbaalenii_PYR-1       YGLVNIAGGAAPATWMPSTRVTREDWRALFAANLETSFFMSQAVGSELRT
MSMEG_5628|M.smegmatis_MC2_155      YGLVNVAGGAAPSTWMPATRVSRADWRELFTANLETMFFMSQAVAAEIRD
TH_1335|M.thermoresistible__bu      --------------------VRRQDWRELFHRNLETAFFMSQAVANEIRA
MAV_5208|M.avium_104                YGLVNVAGGAEPSTWMPSTRVSRTDWRKIFADNLETAFFMSQAVAAELLA
MMAR_0306|M.marinum_M               HGLVNVAGGADPSTWMPSTRVRRSDWHELFARNLEAMFFMSQAIAAELKS
MUL_0327|M.ulcerans_Agy99           TILVNNVGG---VFWSPLLQTSEKGWDALYRSNLGHVLLCTQRVARRLVA
MLBr_01807|M.leprae_Br4923          EVLVANAG---ITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIK
MAB_4680c|M.abscessus_ATCC_199      TGLVNNAG---ISSAAMVADEPLEHFRKVIEINLVGVFIGMQAVIPAMRA
                                                             :  :   *:   :   :     :  

Mb1963c|M.bovis_AF2122/97           QGQGGVIINTASMSGHIINVPQQVSHYCASKAAVIHLTKAMAVELAPHK-
Rv1928c|M.tuberculosis_H37Rv        QGQGGVIINTASMSGHIINVPQQVSHYCASKAAVIHLTKAMAVELAPHK-
Mflv_1787|M.gilvum_PYR-GCK          NGNPGAIVSVSSISG--MNTAPFHIAYGTAKAAIVAMTRTMAVELALDG-
Mvan_4963|M.vanbaalenii_PYR-1       RGLRGSIVSVSSISG--MNTAPFHIAYGTAKAAIVAMTRTMAVELALDD-
MSMEG_5628|M.smegmatis_MC2_155      NGDPGSIVSVSSISG--MNTAPFHIAYGTAKAAIVAATRTMAVELAAAG-
TH_1335|M.thermoresistible__bu      QGNPGSIVSISSISG--MNTAPFHIGYGTAKAAIVAMTRTMAVEHALHG-
MAV_5208|M.avium_104                RRLPGSIVSISSISG--MNTAPFHIAYGTAKSAIAAMTRTMALELAQSA-
MMAR_0306|M.marinum_M               RQRPGSIVSLSSISG--MNAAPFHIGYGTAKAAIVAATRTMALELACDET
MUL_0327|M.ulcerans_Agy99           AGLPGSIMAITSIEG--VRAAPGYAAYAAAKAGVVNYTKTTALELAHHG-
MLBr_01807|M.leprae_Br4923          QR-FGRYIFMGSVVG--LSGVPGQANYAASKSGLIGMARSLARELGSRS-
MAB_4680c|M.abscessus_ATCC_199      HG-CGSIVNISSAAG--LVGLALTSGYGASKWGVRGLSKVAAIELGRER-
                                        *  :   *  *  :        * ::* .:   ::  * * .    

Mb1963c|M.bovis_AF2122/97           -----IRVNSVSPGYILTELVEPY--TEYQPLWEPKIPLGRLGRPEELAG
Rv1928c|M.tuberculosis_H37Rv        -----IRVNSVSPGYILTELVEPY--TEYQPLWEPKIPLGRLGRPEELAG
Mflv_1787|M.gilvum_PYR-GCK          -----IRVNAVAPGVTETAASRMY-VDDDPERDRTAIAMGRRGTPEEQAG
Mvan_4963|M.vanbaalenii_PYR-1       -----IRVNAVAPGVTETAASRTY-VDEDPERDRTAIAMGRRGTPEEQAG
MSMEG_5628|M.smegmatis_MC2_155      -----IRVNAVAPGVTETAASATY-VDADPERDGRAIAMGRRGTPDEQAG
TH_1335|M.thermoresistible__bu      -----IRVNAVAPGVTETAASRTY-VDEDPDRDRTAIAMGRRGRPEEQAG
MAV_5208|M.avium_104                -----IRVNAVAPGVTETAASRTY-VADDPDRDRRAIAMGRRGRPEEQAG
MMAR_0306|M.marinum_M               AAGSPIRVNAVAPGVTETPASHTY-TDVDPERDRRAIAMGRRGRPDEVAG
MUL_0327|M.ulcerans_Agy99           -----IRVNAIAPDITMTEGLAQLGGAAALERIGSLVPLGRPGDVDEIAS
MLBr_01807|M.leprae_Br4923          -----ITANVVAPGFIDTEMTRAM-DSKYQEAALQAIPLGRIGAVEEIAG
MAB_4680c|M.abscessus_ATCC_199      -----IRVNSVHPGVIYTPMTAKE-GFREGEGNMPIAAMGRVGNADEVAG
                                         * .* : *.   *                   .:** *  :* *.

Mb1963c|M.bovis_AF2122/97           LYLYLASEASSYMTGSDIVIDGGYTCP-----------------------
Rv1928c|M.tuberculosis_H37Rv        LYLYLASEASSYMTGSDIVIDGGYTCP-----------------------
Mflv_1787|M.gilvum_PYR-GCK          AILFLLSDLSGYVTGQTLLVDGGLNLKWSHLGADNTSLFLKDESFREVIS
Mvan_4963|M.vanbaalenii_PYR-1       AILFLLSDLSSYITGQTLLVDGGLNLKWSHLAADNTSLFLKDESFRESIR
MSMEG_5628|M.smegmatis_MC2_155      AILFLLSDLSNYVTGQTLLVDGGLNLRWTHLGADNTSLFLKDDNFRAAIT
TH_1335|M.thermoresistible__bu      PILFLLSDLSSYITGQTLLVDGGLNLRWSHLGADNTSLFLRDESFRAAIK
MAV_5208|M.avium_104                AILFLLSELSSYVTGQTLLVDGGLDLRWSHLGADNTSLFLHDESFRAAIR
MMAR_0306|M.marinum_M               VILFLLSDLSSYITGQTLLVDGGLNLKWGHLGADNTSLFLKDESFRAAIK
MUL_0327|M.ulcerans_Agy99           VAVFLASDMARYVTGQTIHVDGGTHAAAGWYRDPQTGEYRLGPG------
MLBr_01807|M.leprae_Br4923          AVSFLASEDAGYISGAVIPVDGGLGMGH----------------------
MAB_4680c|M.abscessus_ATCC_199      AVAYLLSDAASYVTGAELAVDGGWTAGPTLTTITGQ--------------
                                       :* *: : *::*  : :***                           

Mb1963c|M.bovis_AF2122/97           -----
Rv1928c|M.tuberculosis_H37Rv        -----
Mflv_1787|M.gilvum_PYR-GCK          RH---
Mvan_4963|M.vanbaalenii_PYR-1       RI---
MSMEG_5628|M.smegmatis_MC2_155      QP---
TH_1335|M.thermoresistible__bu      EM---
MAV_5208|M.avium_104                RM---
MMAR_0306|M.marinum_M               RWDEA
MUL_0327|M.ulcerans_Agy99           -----
MLBr_01807|M.leprae_Br4923          -----
MAB_4680c|M.abscessus_ATCC_199      -----