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MTTGVSINLDGRIVVVSGAGGGGIGTTVTRLAADAGATVVAVSRSQDNLDEHVVPLAGEGRDVVTVAADA STDDGIATVLDTVRRTPGRLYGLVNIAGGAAPATWMPSTRVTRDDWRALFQANLETAFFMSQAISGEIRS NGNPGAIVSVSSISGMNTAPFHIAYGTAKAAIVAMTRTMAVELALDGIRVNAVAPGVTETAASRMYVDDD PERDRTAIAMGRRGTPEEQAGAILFLLSDLSGYVTGQTLLVDGGLNLKWSHLGADNTSLFLKDESFREVI SRH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1787 | - | - | 100% (283) | short-chain dehydrogenase/reductase SDR |
| M. gilvum PYR-GCK | Mflv_2424 | - | 1e-31 | 34.39% (253) | short-chain dehydrogenase/reductase SDR |
| M. gilvum PYR-GCK | Mflv_1825 | - | 7e-30 | 35.34% (249) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2788c | fabG | 5e-28 | 33.20% (253) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. tuberculosis H37Rv | Rv2766c | fabG | 5e-28 | 33.20% (253) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 4e-20 | 29.67% (246) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0607 | - | 8e-28 | 31.89% (254) | short chain dehydrogenase |
| M. marinum M | MMAR_0306 | - | 1e-109 | 71.63% (282) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_5208 | - | 1e-117 | 77.04% (270) | oxidoreductase, short chain dehydrogenase/reductase family |
| M. smegmatis MC2 155 | MSMEG_5628 | - | 1e-130 | 84.42% (276) | oxidoreductase, short chain dehydrogenase/reductase family |
| M. thermoresistible (build 8) | TH_1335 | - | 3e-79 | 84.71% (170) | oxidoreductase, short chain dehydrogenase/reductase family |
| M. ulcerans Agy99 | MUL_0327 | - | 1e-34 | 36.03% (247) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_4963 | - | 1e-136 | 88.21% (280) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1787|M.gilvum_PYR-GCK ---------MT-TGVSINLDGRIVVVSGAGGGGIGTTVTRLAADAGATVV
Mvan_4963|M.vanbaalenii_PYR-1 ---------MSGTGISIRLDRRIVVVSGAGGGGIGTTVTRLAAEAGATVV
MSMEG_5628|M.smegmatis_MC2_155 ------------MDKLLNLDGRIVVVSGAGGGGIGTTVTRMAAEAGATVV
TH_1335|M.thermoresistible__bu --------------------------------------------------
MAV_5208|M.avium_104 ----------------------MVVVSGAGGGGIGTTVTAMAARAGATVI
MMAR_0306|M.marinum_M -----------MTVDLLSLSGRVVVVAGAAGGGIGTAVTRMVARAGATVV
MUL_0327|M.ulcerans_Agy99 ---------MAIDPADVLLNGRVAVVTGAG-SGIGRGVAAGLAAFGASMA
Mb2788c|M.bovis_AF2122/97 -------------MTSLDLTGRTAIITGAS-RGIGLAIAQQLAAAGAHVV
Rv2766c|M.tuberculosis_H37Rv -------------MTSLDLTGRTAIITGAS-RGIGLAIAQQLAAAGAHVV
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGN-RGIGLAVARRLVADGHRVA
MAB_0607|M.abscessus_ATCC_1997 ----------MRTPYDLGLEGRVVLVTGGV-RGVGAGISQVFADQGATVV
Mflv_1787|M.gilvum_PYR-GCK AVSRSQDNLDEHVVPLAGEGRDVVTVAADASTDDGIATVLDTVRRTPGRL
Mvan_4963|M.vanbaalenii_PYR-1 AVSRSKDNLDEHVVPLARKGLSVVPVAADASTDDGIATVLDHVRRTDGDL
MSMEG_5628|M.smegmatis_MC2_155 AVSRSQDNLDTHVGPLADKGLSVVTVAADASTDDGIATVLDAVRRTDGRL
TH_1335|M.thermoresistible__bu --------------------------------------------------
MAV_5208|M.avium_104 AVSRSKENLDEHIAPLAAQGLAVLPVAADASTDEGIAAVIDQARRADGQL
MMAR_0306|M.marinum_M AVSRGQDNLDRQVGPLVAEGLAVLPVAADVCTDEGIEATLEAVRRADGDL
MUL_0327|M.ulcerans_Agy99 IWERDPQTCAQAAAELGGLG-----IATDVRSGDQVDAALQRTQAELGAV
Mb2788c|M.bovis_AF2122/97 LTARRQEAADEAAAQVGDRALG---VGAHAVDEDAARRCVDLTLERFGSV
Rv2766c|M.tuberculosis_H37Rv LTARRQEAADEAAAQVGDRALG---VGAHAVDEDAARRCVDLTLERFGSV
MLBr_01807|M.leprae_Br4923 VTHR--------ASVVPDWFFG---VECDVTDNDAIGAAFKAVEEHQGPV
MAB_0607|M.abscessus_ATCC_1997 TCARR-------PGDAPYEFH-----SCDVRDEESVDTLIGAIVAAHGRL
Mflv_1787|M.gilvum_PYR-GCK YGLVNIAGGAAPATWMPSTRVTRDDWRALFQANLETAFFMSQAISGEIRS
Mvan_4963|M.vanbaalenii_PYR-1 YGLVNIAGGAAPATWMPSTRVTREDWRALFAANLETSFFMSQAVGSELRT
MSMEG_5628|M.smegmatis_MC2_155 YGLVNVAGGAAPSTWMPATRVSRADWRELFTANLETMFFMSQAVAAEIRD
TH_1335|M.thermoresistible__bu --------------------VRRQDWRELFHRNLETAFFMSQAVANEIRA
MAV_5208|M.avium_104 YGLVNVAGGAEPSTWMPSTRVSRTDWRKIFADNLETAFFMSQAVAAELLA
MMAR_0306|M.marinum_M HGLVNVAGGADPSTWMPSTRVRRSDWHELFARNLEAMFFMSQAIAAELKS
MUL_0327|M.ulcerans_Agy99 TILVNNVGG---VFWSPLLQTSEKGWDALYRSNLGHVLLCTQRVARRLVA
Mb2788c|M.bovis_AF2122/97 DILINNAGTN--PAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMG
Rv2766c|M.tuberculosis_H37Rv DILINNAGTN--PAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMG
MLBr_01807|M.leprae_Br4923 EVLVANAGIT--SDM-LIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIK
MAB_0607|M.abscessus_ATCC_1997 DAVVNNAGG---APFALAADASHNFHRKIIELNLLSALLVSQRANAVMQK
. : ** : :.
Mflv_1787|M.gilvum_PYR-GCK NGNPGAIVSVSSISGMNTAPFHIAYGTAKAAIVAMTRTMAVELALDG---
Mvan_4963|M.vanbaalenii_PYR-1 RGLRGSIVSVSSISGMNTAPFHIAYGTAKAAIVAMTRTMAVELALDD---
MSMEG_5628|M.smegmatis_MC2_155 NGDPGSIVSVSSISGMNTAPFHIAYGTAKAAIVAATRTMAVELAAAG---
TH_1335|M.thermoresistible__bu QGNPGSIVSISSISGMNTAPFHIGYGTAKAAIVAMTRTMAVEHALHG---
MAV_5208|M.avium_104 RRLPGSIVSISSISGMNTAPFHIAYGTAKSAIAAMTRTMALELAQSA---
MMAR_0306|M.marinum_M RQRPGSIVSLSSISGMNAAPFHIGYGTAKAAIVAATRTMALELACDETAA
MUL_0327|M.ulcerans_Agy99 AGLPGSIMAITSIEGVRAAPGYAAYAAAKAGVVNYTKTTALELAHHG---
Mb2788c|M.bovis_AF2122/97 EHGG-AVVNTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSPR----
Rv2766c|M.tuberculosis_H37Rv EHGG-AVVNTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSPR----
MLBr_01807|M.leprae_Br4923 QRFG-RYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRS---
MAB_0607|M.abscessus_ATCC_1997 QDGGGTIVNITSVSAGRPSPGTAAYGAAKAGLESLTRSLAVEWAPK----
: *: . * * ::*:.: :: * * .
Mflv_1787|M.gilvum_PYR-GCK ---IRVNAVAPGVTETAASRMY-VDDDP-ERDRTAIAMGRRGTPEEQAGA
Mvan_4963|M.vanbaalenii_PYR-1 ---IRVNAVAPGVTETAASRTY-VDEDP-ERDRTAIAMGRRGTPEEQAGA
MSMEG_5628|M.smegmatis_MC2_155 ---IRVNAVAPGVTETAASATY-VDADP-ERDGRAIAMGRRGTPDEQAGA
TH_1335|M.thermoresistible__bu ---IRVNAVAPGVTETAASRTY-VDEDP-DRDRTAIAMGRRGRPEEQAGP
MAV_5208|M.avium_104 ---IRVNAVAPGVTETAASRTY-VADDP-DRDRRAIAMGRRGRPEEQAGA
MMAR_0306|M.marinum_M GSPIRVNAVAPGVTETPASHTY-TDVDP-ERDRRAIAMGRRGRPDEVAGV
MUL_0327|M.ulcerans_Agy99 ---IRVNAIAPDITMTEGLAQLGGAAAL-ERIGSLVPLGRPGDVDEIASV
Mb2788c|M.bovis_AF2122/97 ---IRVNAICPGVVRTRLAEALWKDHE--DPLAATIALGRIGEPADIASA
Rv2766c|M.tuberculosis_H37Rv ---IRVNAICPGVVRTRLAEALWKDHE--DPLAATIALGRIGEPADIASA
MLBr_01807|M.leprae_Br4923 ---ITANVVAPGFIDTEMTRAMDSKYQ--EAALQAIPLGRIGAVEEIAGA
MAB_0607|M.abscessus_ATCC_1997 ---VRVNALAAGMIRTELSEMHYGDEDGIAAVGATVPLGRLANPDEIGWT
: .*.:.... * :.:** . : .
Mflv_1787|M.gilvum_PYR-GCK ILFLLSDLSGYVTGQTLLVDGGLNLKWSHLGADNTSLFLKDESFREVISR
Mvan_4963|M.vanbaalenii_PYR-1 ILFLLSDLSSYITGQTLLVDGGLNLKWSHLAADNTSLFLKDESFRESIRR
MSMEG_5628|M.smegmatis_MC2_155 ILFLLSDLSNYVTGQTLLVDGGLNLRWTHLGADNTSLFLKDDNFRAAITQ
TH_1335|M.thermoresistible__bu ILFLLSDLSSYITGQTLLVDGGLNLRWSHLGADNTSLFLRDESFRAAIKE
MAV_5208|M.avium_104 ILFLLSELSSYVTGQTLLVDGGLDLRWSHLGADNTSLFLHDESFRAAIRR
MMAR_0306|M.marinum_M ILFLLSDLSSYITGQTLLVDGGLNLKWGHLGADNTSLFLKDESFRAAIKR
MUL_0327|M.ulcerans_Agy99 AVFLASDMARYVTGQTIHVDGGTHAAAGWYRDPQTGEYRLGPG-------
Mb2788c|M.bovis_AF2122/97 VAFLVSDAASWITGETMIIDGGLLLGNALGFRAAPSTEH-----------
Rv2766c|M.tuberculosis_H37Rv VAFLVSDAASWITGETMIIDGGLLLGNALGFRAAPSTEH-----------
MLBr_01807|M.leprae_Br4923 VSFLASEDAGYISGAVIPVDGGLGMGH-----------------------
MAB_0607|M.abscessus_ATCC_1997 AAFLASPLSSYVTGSVLTVHGGGERPAFLDAANVNSNENGEKE-------
** * : :::* .: :.**
Mflv_1787|M.gilvum_PYR-GCK H---
Mvan_4963|M.vanbaalenii_PYR-1 I---
MSMEG_5628|M.smegmatis_MC2_155 P---
TH_1335|M.thermoresistible__bu M---
MAV_5208|M.avium_104 M---
MMAR_0306|M.marinum_M WDEA
MUL_0327|M.ulcerans_Agy99 ----
Mb2788c|M.bovis_AF2122/97 ----
Rv2766c|M.tuberculosis_H37Rv ----
MLBr_01807|M.leprae_Br4923 ----
MAB_0607|M.abscessus_ATCC_1997 ----