For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2406 | - | 100% (418) | PROBABLE CONSERVED INTEGRAL MEMBRANE TRANSPORT PROTEIN | |
| M. thermoresistible (build 8) | TH_1986 | - | 6e-23 | 27.53% (396) | tetracycline-resistance determinant TetV |
| M. thermoresistible (build 8) | TH_1317 | - | 1e-20 | 25.00% (412) | transmembrane transport protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1288c | - | 1e-148 | 65.12% (410) | integral membrane transport protein |
| M. gilvum PYR-GCK | Mflv_2234 | - | 1e-176 | 77.36% (402) | H+ antiporter protein |
| M. tuberculosis H37Rv | Rv1258c | - | 1e-148 | 65.12% (410) | integral membrane transport protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1409c | - | 1e-131 | 56.75% (400) | putative drug antiporter protein precursor |
| M. marinum M | MMAR_4182 | - | 1e-148 | 64.23% (411) | hypothetical protein MMAR_4182 |
| M. avium 104 | MAV_1406 | - | 1e-143 | 63.80% (395) | transporter, major facilitator family protein |
| M. smegmatis MC2 155 | MSMEG_5187 | - | 6e-22 | 26.58% (395) | tetracycline-resistance determinant TetV |
| M. ulcerans Agy99 | MUL_3826 | - | 2e-06 | 19.68% (188) | hypothetical protein MUL_3826 |
| M. vanbaalenii PYR-1 | Mvan_4461 | - | 1e-177 | 77.04% (405) | H+ antiporter protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2234|M.gilvum_PYR-GCK -------------------MTPDTTPRSRTPLLLIMFAALMAGAGNGISI
Mvan_4461|M.vanbaalenii_PYR-1 -------------------MTPNEAPSRRGPLLLILFAALMAGAGNGISL
TH_2406|M.thermoresistible__bu -----------------------MSTSTRGPVLLIYSAALTAGAGNGISI
Mb1288c|M.bovis_AF2122/97 -----------------------MRNSNRGPAFLILFATLMAAAGDGVSI
Rv1258c|M.tuberculosis_H37Rv -----------------------MRNSNRGPAFLILFATLMAAAGDGVSI
MMAR_4182|M.marinum_M -----------------------MRNSSRGPAFLILFATLAACAGNGISI
MAV_1406|M.avium_104 ---------------------------------MILFATLLATAGTGISI
MAB_1409c|M.abscessus_ATCC_199 -------------MSTPTADSPTINQVNRGPVLLLLFASVVAAIGNGVSI
MSMEG_5187|M.smegmatis_MC2_155 -----------MRSPRPVAGWRVLAPFRIREYRLLIAAVTLSIFAEGMWS
MUL_3826|M.ulcerans_Agy99 MMRPRATVAAATPTTDLAAGRALITPRRRNFIFVALVLGILLSSLDQTIV
:
Mflv_2234|M.gilvum_PYR-GCK VAFPWLVLQRTGSALDASIVAMAGTLPLLAATLIAGAAVDFLGRR-----
Mvan_4461|M.vanbaalenii_PYR-1 VAFPWLVLQRTGSALDASIVAMAGTLPLLAATLIAGAAVDFLGRR-----
TH_2406|M.thermoresistible__bu IAFPWLVLQRNGSALEASVVAMAATXPLLVATLFAGVAVDYLGRR-----
Mb1288c|M.bovis_AF2122/97 VAFPWLVLQREGSAGQASIVASATMLPLLFATLVAGTAVDYFGRR-----
Rv1258c|M.tuberculosis_H37Rv VAFPWLVLQREGSAGQASIVASATMLPLLFATLVAGTAVDYFGRR-----
MMAR_4182|M.marinum_M VAFPWLVLEREGSAGQASIVAGAITLPLLFSTLVAGTAVDYFGRR-----
MAV_1406|M.avium_104 VAFPWLALQHRHSATDASIVAAAMTLPLVLATLIAGTAVDFFGRR-----
MAB_1409c|M.abscessus_ATCC_199 VALPWLVLQRNGSAADAAIVAAAGTLPLVFSTLISGTAVDYFGRR-----
MSMEG_5187|M.smegmatis_MC2_155 VVMALQVIAIDNDPASLSLVATCLGVGLVAFVLVGGITADRINQR-----
MUL_3826|M.ulcerans_Agy99 AIALPTIVADLGEAGRQSWVVTSYLLASTIATALVGKLGDMFGRKRVFQV
: .. : *. . . . * * :.::
Mflv_2234|M.gilvum_PYR-GCK --RVSMISDALSALSVAAVPVIALVFGADAVNVAVLA-ALAALGAFFDPA
Mvan_4461|M.vanbaalenii_PYR-1 --RVSMISDALSALSVAAVPVLALAFGTDVINVAVLA-GLAALGAIFDPA
TH_2406|M.thermoresistible__bu --RVSMISDLLSALSVAAVPVIALTFGVQAVNVAVLA-ALAALGAFFDPA
Mb1288c|M.bovis_AF2122/97 --RVSMVADALSGAAVAGVPLVAWGYGGDAVNVLVLA-VLAALAAAFGPA
Rv1258c|M.tuberculosis_H37Rv --RVSMVADALSGAAVAGVPLVAWGYGGDAVNVLVLA-VLAALAAAFGPA
MMAR_4182|M.marinum_M --PVSMVSDALSGSAVAIVPLIAWAFGDDAVSVAVLA-ALGACSATFDPA
MAV_1406|M.avium_104 --RVSLVCDWLSGAAVTAVPLTAWIFGAAAIDVAELA-VLAFCAAAFDPA
MAB_1409c|M.abscessus_ATCC_199 --VMSIFSDVLSLVSVSAIPILAMTTG---LNVPLLA-ALAALGAIFDPA
MSMEG_5187|M.smegmatis_MC2_155 --TIIIAVEVVNFVTVAVISALALLGVLKIWHMAVAAGILGIAAAFFFPA
MUL_3826|M.ulcerans_Agy99 AVLLFVAGSVSCGLTQSMTMLVASRALQGVGGGAITVTAIALIGEVVPLR
: : . : : * . :. . .
Mflv_2234|M.gilvum_PYR-GCK GMTARETMLPEAAHRAGWTLDRANSFFEAVF--NLAYIVGPGIGGLLIAT
Mvan_4461|M.vanbaalenii_PYR-1 GMTARETMLPEAANRAGWTLDHANSVFEAIF--NLAYIVGPGIGGLLIAT
TH_2406|M.thermoresistible__bu GMTARETMLPEAAARAGWTLDKTNSGYEAIF--NLAYIVGPGIGGLLIAT
Mb1288c|M.bovis_AF2122/97 GMTARDSMLPEAAARAGWSLDRINGAYEAIL--NLAFIVGPAIGGLMIAT
Rv1258c|M.tuberculosis_H37Rv GMTARDSMLPEAAARAGWSLDRINGAYEAIL--NLAFIVGPAIGGLMIAT
MMAR_4182|M.marinum_M GITARQSMLPEAAARAGWSLDRINSSYEAIL--NLAFVVGPGIGGLMIAT
MAV_1406|M.avium_104 GMTARQSMLPEAAARAGWSLDRTNSSYEAML--NLAFIVGPGLGGLLIAT
MAB_1409c|M.abscessus_ATCC_199 GITARESMLPAAAKSAGWSLDKMNSMYEATF--NVAYIVGPGLGGLLIAS
MSMEG_5187|M.smegmatis_MC2_155 YSAILPRILPPEQLLA---ANGVEGVVRPVF--QRS--VGPAVAGMVIGA
MUL_3826|M.ulcerans_Agy99 DRGRYQGILGAVIGIATIGGPLLGGYFTDCLGWRWAFWINLPVSAVVICV
:* * . : . : :. :..::*
Mflv_2234|M.gilvum_PYR-GCK LGGIDTMWVTAGAFVLSIAAIAVLRLEGTARPDPSTMSDGVWAGILEGLR
Mvan_4461|M.vanbaalenii_PYR-1 LGGIDTMWVTAGAFGLSIFAIAALKLEGAGRPDPTAMSDGVWAGIIEGLR
TH_2406|M.thermoresistible__bu LGGVNTMWVTAALFVVSIVTIAALRLEGAGLPDRALLTDSVLAGIVEGLR
Mb1288c|M.bovis_AF2122/97 VGGITTMWITATAFGLSILAIAALQLEGAGKPHHTSRPQGLVSGIAEGLR
Rv1258c|M.tuberculosis_H37Rv VGGITTMWITATAFGLSILAIAALQLEGAGKPHHTSRPQGLVSGIAEGLR
MMAR_4182|M.marinum_M VGGITTMWITAGAFGLSLLAIGALRLEGAGRPHHETRPDGLVSGVTQGLR
MAV_1406|M.avium_104 LGGINTMWVTAGCFALSFLAIGALRLEGAGKPPRATRPVGLVTGIAEGVR
MAB_1409c|M.abscessus_ATCC_199 VGGVNTMWVTAASFVVSIIAIALLKVDGAGKPAHETRPTGVFSGVLEGLR
MSMEG_5187|M.smegmatis_MC2_155 TMPSIGAVVVAVLFALGLALLVATRPPAQPASEHHERP-HVLRDLREGFA
MUL_3826|M.ulcerans_Agy99 ATAAIPALAATTRPVIDYAGIMFIGLSLAALTLATSLGGSVYAWGSAPII
.: :. : . : .
Mflv_2234|M.gilvum_PYR-GCK ------------FVWNNKVLRT--------------LAFVDLAATGLYMP
Mvan_4461|M.vanbaalenii_PYR-1 ------------FVWRNKVLRT--------------LALVDLVATGLYVP
TH_2406|M.thermoresistible__bu ------------FVWRTPVLRA--------------LLIVDLVVTGLYMP
Mb1288c|M.bovis_AF2122/97 ------------FVWNLRVLRT--------------LGMIDLTVTALYLP
Rv1258c|M.tuberculosis_H37Rv ------------FVWNLRVLRT--------------LGMIDLTVTALYLP
MMAR_4182|M.marinum_M ------------FVWNLRVLRA--------------LALIDLTVTALYLP
MAV_1406|M.avium_104 ------------FVWNLRVLRT--------------LGLIDLAVTALYLP
MAB_1409c|M.abscessus_ATCC_199 ------------FFWNIKILRT--------------IALVDMAITALYLP
MSMEG_5187|M.smegmatis_MC2_155 ------------FVLKTPWLLW--------------TVLFASMFVLVVLG
MUL_3826|M.ulcerans_Agy99 GLFTAAGVTLAVFVWVETIAAQPILPIRLFAAPVFSVCCVLAFVVGFAML
*. . . . :
Mflv_2234|M.gilvum_PYR-GCK MESVLFPKYFTD--RDEPAQLGWVLMALSIGGLLGALGFAVLS-------
Mvan_4461|M.vanbaalenii_PYR-1 MESVLFPKYFTD--RNEPAQLGWVLMALSIGGLIGALGYAVMS-------
TH_2406|M.thermoresistible__bu MESVLFPKYFTD--RDEPAHLGWVLMALSIGGLTGALAYAWVS-------
Mb1288c|M.bovis_AF2122/97 MESVLFPKYFTD--HQQPVQLGWALMAIAGGGLVGALGYAVLA-------
Rv1258c|M.tuberculosis_H37Rv MESVLFPKYFTD--HQQPVQLGWALMAIAGGGLVGALGYAVLA-------
MMAR_4182|M.marinum_M MESVLFPTYFSD--RQQPAQLGSVLVALSLGSLVGALGYGMLS-------
MAV_1406|M.avium_104 MESVLFPKYFAD--QHQPAQLGWALMALALGGVAGALGYAVLS-------
MAB_1409c|M.abscessus_ATCC_199 IESVLLPKHFSD--IGAPQQLGWMLMAISVGGLLGALGYATMV-------
MSMEG_5187|M.smegmatis_MC2_155 PIEVLLPFIAQDRFADGARAYGFILAFFGIGSAMGALTVSSRR-------
MUL_3826|M.ulcerans_Agy99 GALIFVPTFMQYVNGVSATASGLRILPMVIGMLITSIGSGSMVGRTGRYK
::.* . * : : * :: .
Mflv_2234|M.gilvum_PYR-GCK -KYLKRRTVMLTAVLTLGVAMTVIAFLPPLPIILVLCALVGFVYGPIAPI
Mvan_4461|M.vanbaalenii_PYR-1 -RYMKRRTVMLTAVLTLGVAMTVIAFLPPLPIILVLCAIVGFVYGPIAPI
TH_2406|M.thermoresistible__bu -RFVSRRATLITAVLTLGATMTVIAFLPPLPLILAMAAVGGFAYGPIQPI
Mb1288c|M.bovis_AF2122/97 -IRVPRRVTMSTAVLTLGLASMVIAFLPPLPVIMVLCAVVGLVYGPIQPI
Rv1258c|M.tuberculosis_H37Rv -IRVPRRVTMSTAVLTLGLASMVIAFLPPLPVIMVLCAVVGLVYGPIQPI
MMAR_4182|M.marinum_M -NYVSRRTIMLTAVLTLGAATTGIALLPPLPVILVLCALIGVVYGPIQPI
MAV_1406|M.avium_104 -ARLRRRTAVLTATLTFGATTAGIAVLPPLPVILGLCAVTGVVYGPIQPI
MAB_1409c|M.abscessus_ATCC_199 -RHFQRRTIMLCATFTAGITTLGMSLLPPIAVLLVLAACLGFIYGPVAPI
MSMEG_5187|M.smegmatis_MC2_155 -MPRRYLTTMMLMWGLGSIPLVIVGYTSSFPLMAAATFVIGVTDGAGMVI
MUL_3826|M.ulcerans_Agy99 IFPVLGTALMTLAFLLMSRTDESTSAAVQSVYLLILGSAIGMSSQVLVII
. : . . . : *. *
Mflv_2234|M.gilvum_PYR-GCK YN---------------------------YVMQTRAPQHLRGRVVGVMGS
Mvan_4461|M.vanbaalenii_PYR-1 YN---------------------------YVMQTRAPQHLRGRVVGVMGS
TH_2406|M.thermoresistible__bu YN---------------------------YVMQTRAPQHLRGRVVGVMGS
Mb1288c|M.bovis_AF2122/97 YN---------------------------YVIQTRAAQHLRGRVVGVMTS
Rv1258c|M.tuberculosis_H37Rv YN---------------------------YVIQTRAAQHLRGRVVGVMTS
MMAR_4182|M.marinum_M YN---------------------------YVMQTRAPHYLRGRVVGVMTS
MAV_1406|M.avium_104 YN---------------------------FVMQTRAPHHLRGRVVGVMAG
MAB_1409c|M.abscessus_ATCC_199 AN---------------------------FVMQTRSPEHLRGRVVGVMTS
MSMEG_5187|M.smegmatis_MC2_155 WG---------------------------TLLQRRVPTEMLGRVSSLDFF
MUL_3826|M.ulcerans_Agy99 VQNTSEFEDLGVATSGVSLFRTIGGSFGAAIFGSLFVNFLNSRLASALTA
:: : .*: .
Mflv_2234|M.gilvum_PYR-GCK LAYAAGPLGLILAGPLADSAGLHVTFLALSLPMLALGIVSVF--------
Mvan_4461|M.vanbaalenii_PYR-1 LAYAAGPLGLILAGPLADATGLRTTFLALSLPMLALGIVAVF--------
TH_2406|M.thermoresistible__bu LAYAAGPLGLVIAGPLADSAGLRVTFLALSLPMVALGLIAIG--------
Mb1288c|M.bovis_AF2122/97 LAYAAGPLGLLLAGPLTDAAGLHATFLALALPIVCTGLVAIR--------
Rv1258c|M.tuberculosis_H37Rv LAYAAGPLGLLLAGPLTDAAGLHATFLALALPIVCTGLVAIR--------
MMAR_4182|M.marinum_M LAYAAGPLGLLLAGPVADAAGLKVAFFALALPIAITGLMCIR--------
MAV_1406|M.avium_104 LTYAAGPLGLLVAGPLADAAGLKATFLTLAVPILAIGVVACG--------
MAB_1409c|M.abscessus_ATCC_199 TAYCAGPLGFMLAGPIADKFGVATTLVILGAPMLLIAIASTR--------
MSMEG_5187|M.smegmatis_MC2_155 VSLAFMPLSFAIVGPLSKVVSMEVIFATAGLVPVAIAAVAFT--------
MUL_3826|M.ulcerans_Agy99 TEVASSPEALHRQSPAVAAPIVHAYAGSLAQVFLCAAPVAAIGFVLALFM
. * .: .* : . . . .
Mflv_2234|M.gilvum_PYR-GCK ----LPALRELDTPHP----------------------------------
Mvan_4461|M.vanbaalenii_PYR-1 ----LPALRDLDRPAAGP--------------------------------
TH_2406|M.thermoresistible__bu ----LPVLTTLNQPAADQIDLQFDD-------------------------
Mb1288c|M.bovis_AF2122/97 ----LPALRELDLAPQADIDRPVGSAQ-----------------------
Rv1258c|M.tuberculosis_H37Rv ----LPALRELDLAPQADIDRPVGSAQ-----------------------
MMAR_4182|M.marinum_M ----LPSLRELDHAPTQDISETSLL-------------------------
MAV_1406|M.avium_104 ----LPSLRELDRAPQFADDPGA---------------------------
MAB_1409c|M.abscessus_ATCC_199 ----MRVLRELDQDEPQPDKEPTR--------------------------
MSMEG_5187|M.smegmatis_MC2_155 ----AARMHRDEVANPLL--------------------------------
MUL_3826|M.ulcerans_Agy99 REVPLRDIHNRDHDARVPSGDGSGQQNKLEGDLDTGQSVGAPGKEPDFGV
: :
Mflv_2234|M.gilvum_PYR-GCK --------
Mvan_4461|M.vanbaalenii_PYR-1 --------
TH_2406|M.thermoresistible__bu --------
Mb1288c|M.bovis_AF2122/97 --------
Rv1258c|M.tuberculosis_H37Rv --------
MMAR_4182|M.marinum_M --------
MAV_1406|M.avium_104 --------
MAB_1409c|M.abscessus_ATCC_199 --------
MSMEG_5187|M.smegmatis_MC2_155 --------
MUL_3826|M.ulcerans_Agy99 DPAMGPVR