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TDTSAETTILTEDSTDQRLLNAAERLFAERGVDAVSLRAIMAAAGTNVASVHYHFGSKERLIEALLDRYL DQIEKRRFALLDVAETARTLRAIAEAIVTPLSEIAEEGSTAWLSTLGKLLISGHPALIPMSVSFQPQAAR LQELILRLRPDATLPSIRFGVTHAVTLTCVVLGDIAHTNRLMSLSGTYLDDGQMNAQLIDMVTAILAGPP DES*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0835c | - | - | 100% (214) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1578c | - | 1e-10 | 43.53% (85) | putative transcriptional regulator TetR |
| M. abscessus ATCC 19977 | MAB_0483c | - | 8e-10 | 43.37% (83) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1711c | - | 6e-09 | 42.11% (57) | hypothetical protein Mb1711c |
| M. gilvum PYR-GCK | Mflv_2416 | - | 7e-12 | 32.39% (142) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1685c | - | 6e-09 | 42.11% (57) | hypothetical protein Rv1685c |
| M. leprae Br4923 | MLBr_00949 | - | 9e-05 | 30.77% (52) | hypothetical protein MLBr_00949 |
| M. marinum M | MMAR_4764 | - | 7e-12 | 41.35% (104) | hypothetical protein MMAR_4764 |
| M. avium 104 | MAV_2967 | - | 5e-11 | 38.05% (113) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_4858 | - | 2e-12 | 40.59% (101) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2278 | - | 6e-12 | 31.69% (142) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_0335 | - | 3e-12 | 42.31% (104) | hypothetical protein MUL_0335 |
| M. vanbaalenii PYR-1 | Mvan_2880 | - | 3e-13 | 39.82% (113) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1711c|M.bovis_AF2122/97 -------------------------MAAPDNSRRRPGRPAGSSDTRERIL
Rv1685c|M.tuberculosis_H37Rv -------------------------MAAPDNSRRRPGRPAGSSDTRERIL
MMAR_4764|M.marinum_M -----------------------------MTAVGRAVRGERASSTQEAIL
MUL_0335|M.ulcerans_Agy99 -----------------------------MTAVGRAVRGERASSTQEAIL
Mflv_2416|M.gilvum_PYR-GCK MQSGATTFLNGTTHLKQSLDLPGVTRFTDRVTTARTVRADRATGTQEAIL
MSMEG_4858|M.smegmatis_MC2_155 --------------MTRFTGLVTTASRTASRTAARTARADRATSTQEAIL
TH_2278|M.thermoresistible__bu -----------------------VVQFTEGVTAARTVRADRASSTQEAIL
MAV_2967|M.avium_104 -------------------------MFTEAMTAERIARSDRSTGTREAIL
MAB_0835c|M.abscessus_ATCC_199 ---------------------------MTDTSAETTILTEDS--TDQRLL
Mvan_2880|M.vanbaalenii_PYR-1 -------------------------------------MSRIEADTREHLL
MLBr_00949|M.leprae_Br4923 -----------------------------MTTSARTHRWAKTGAIQRRIL
. :*
Mb1711c|M.bovis_AF2122/97 SSARELFAHNGIDRTSIRAVAAKAG-VDAALVHHYFGTKQQLFAAAIHIP
Rv1685c|M.tuberculosis_H37Rv SSARELFAHNGIDRTSIRAVAAKAG-VDAALVHHYFGTKQQLFAAAIHIP
MMAR_4764|M.marinum_M VAAERLFAEHGVFAVSNRQVSEAAGQGNNAAVGYHFGTKTDLVRAIEQKH
MUL_0335|M.ulcerans_Agy99 VAAERLFAEHGVFAVSNRQVSEAAGQGNNAAVGYHFGTKTDLVRAIEQKH
Mflv_2416|M.gilvum_PYR-GCK KAAERLYAEHGVFAVSNRQVSEAAGQGNNAAVGYHFGTKADLVRAIEHKH
MSMEG_4858|M.smegmatis_MC2_155 KAAERLYAEHGVFAVSNRQVSEAAGQGNNAAVGYHFGTKTDLVRAIEHKH
TH_2278|M.thermoresistible__bu KAAERLYAERGMFAVSNRQVSEAAGQGNNAAVGYHFGTKTDLVRAIEQKH
MAV_2967|M.avium_104 SAAEVLFAERGMYAVSNRQISEAAGQGNNAAACYHFGTRVDLLRAIEGKH
MAB_0835c|M.abscessus_ATCC_199 NAAERLFAERGVDAVSLRAIMAAAG-TNVASVHYHFGSKERLIEALLDRY
Mvan_2880|M.vanbaalenii_PYR-1 TVAERLFLDAGYENVSVRAVCATAG-VNPAAVHYHFGSKVGLVSALLEAR
MLBr_00949|M.leprae_Br4923 DAAIEVFATRSFTTATMTDAMTGSG-AIIGSIYHHFGGKRKLFLAIFEQM
* :: . .: :* . ::** : *. *
Mb1711c|M.bovis_AF2122/97 IDPMVIIGPIREAPVEELG-----------------YKLPSLLLPIWDSE
Rv1685c|M.tuberculosis_H37Rv IDPMVIIGPIREAPVEELG-----------------YKLPSLLLPIWDSE
MMAR_4764|M.marinum_M RVPVERLREQMVAAAAAKGVAATMRDWVACLVCPLTEHLAVLGNPTWYAR
MUL_0335|M.ulcerans_Agy99 RVPIERLREQMVAAAAAKGAAATMRDWVACLVCPLTEHLAVLGNPTWYAR
Mflv_2416|M.gilvum_PYR-GCK RGPIEELREQRVAAIDSSG---DMRDWVAALVCPLTDHLAALGNPTWYAR
MSMEG_4858|M.smegmatis_MC2_155 RGPIEYLREQMIGTVQGST---DLRDWVGALVRPLTDHLAALGNPTWYAR
TH_2278|M.thermoresistible__bu RVEIERLLEKMVAETGDST---DLRDWVACLVCSLTEHLHQLGNPTWYAR
MAV_2967|M.avium_104 REPIEKLRAQMLAAVGDST---ELRDWVGTLVRPLTDHLSALGTPSWYAR
MAB_0835c|M.abscessus_ATCC_199 LDQIEKRRFALLDVAETAR----TLRAIAEAIVTPLSEIAEEGSTAWLST
Mvan_2880|M.vanbaalenii_PYR-1 LGPLWEDALTEAAGEGPAG----ISDAVRIVVEPLVELAGDPAGRLYLHL
MLBr_00949|M.leprae_Br4923 GRQRRPPHRRGDATSGPIR--------------------------PSGDR
Mb1711c|M.bovis_AF2122/97 LGAGLIA-TLRSLISGSDVGLARSFLEEVVTVELGSRVDNPPGTGKIRTQ
Rv1685c|M.tuberculosis_H37Rv LGAGLIA-TLRSLISGSDVGLARSFLEEVVTVELGSRVDNPPGTGKIRTQ
MMAR_4764|M.marinum_M FAAQAMT-DPAYHNIIVKDALSSPSLVQVIDGINSCLPDLPVDVRYERNL
MUL_0335|M.ulcerans_Agy99 FAAQAMT-DPAYHNIIVKDALSSPSLVQVIDGINSCLPDLPVDVRYERNL
Mflv_2416|M.gilvum_PYR-GCK FAAQVMT-DPAYHNMIVKDALSSPSLVRVLDGINGCLPDLPVDVRVERNI
MSMEG_4858|M.smegmatis_MC2_155 FAAQVMT-DPAYHNIIVRDALSSPSLVQVIEGMNNCLPDLPAEIRAERNI
TH_2278|M.thermoresistible__bu FAAQALA-DPAYQKIVVKDALASPALVRVVEGITRCLPDLPAAVVVERNI
MAV_2967|M.avium_104 FAAQAMA-DPSYRHVVTKDALSSPLLVRTLDGINRCLPELPRRVRAERMV
MAB_0835c|M.abscessus_ATCC_199 LGKLLISGHPALIPMSVSFQPQAARLQELILRLRPDATLPSIRFGVTHAV
Mvan_2880|M.vanbaalenii_PYR-1 LSRLLLA---RVELSWTRRWFAVAPWVALLRRHLPELSERDAEARWMLAF
MLBr_00949|M.leprae_Br4923 SAAGIRS---------PRTGPTSRRCGKTGTRPGCCRPETHLQASRSPVA
. :
Mb1711c|M.bovis_AF2122/97 FVASQLMG--VVMARYIVRIEPFASLPAEQIVQTIAPNLQRYLTGELPDD
Rv1685c|M.tuberculosis_H37Rv FVASQLMG--VVMARYIVRIEPFASLPAEQIVQTIAPNLQRYLTGELPDD
MMAR_4764|M.marinum_M MARNLLMHTCADLERALAAGTSVPRPSWREAATGLIDAITGLWLAPVTAR
MUL_0335|M.ulcerans_Agy99 MARNLLMHTCADLERALAAGTSVPRPFWREAATGQIDAITGLWLAPVTAR
Mflv_2416|M.gilvum_PYR-GCK MGRNLLMHSCADRERLLAQGSPVPRGSWQSAATGLIDAIIGLWHAPVTER
MSMEG_4858|M.smegmatis_MC2_155 MARNLLMHSCAERERALAQGAPVPRSSWQGAASGLIDAIVGLWLAPVTGE
TH_2278|M.thermoresistible__bu MARNLLMHTCADFERAFAEGDPVPRASWQAVGNGLIDAIVGLWRAPVTEP
MAV_2967|M.avium_104 MVRNLLMHTCAEHEGALAEHGPRSRSAWPVAAEGLIDAIVGLWRAPVHVA
MAB_0835c|M.abscessus_ATCC_199 TLTCVVLGDIAHTNRLMSLSGTYLDD--GQMNAQLIDMVTAILAGPPDES
Mvan_2880|M.vanbaalenii_PYR-1 ELIFTQFGDPLAGDRRLSARR----------VQTLQAFVAAGLSAPVESR
MLBr_00949|M.leprae_Br4923 TA------------------------------------------------
Mb1711c|M.bovis_AF2122/97 LAP--------------------
Rv1685c|M.tuberculosis_H37Rv LAP--------------------
MMAR_4764|M.marinum_M E----------------------
MUL_0335|M.ulcerans_Agy99 E----------------------
Mflv_2416|M.gilvum_PYR-GCK P----------------------
MSMEG_4858|M.smegmatis_MC2_155 DR---------------------
TH_2278|M.thermoresistible__bu PQ---------------------
MAV_2967|M.avium_104 AAAGPTGQTTAPATGQTDHRGAP
MAB_0835c|M.abscessus_ATCC_199 -----------------------
Mvan_2880|M.vanbaalenii_PYR-1 -----------------------
MLBr_00949|M.leprae_Br4923 -----------------------