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M. thermoresistible (build 8) TH_2023 (-)

annotation: transcriptional regulator, TetR family protein
coordinates: 3954240 - 3954896
length: 219

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2023--100% (219)transcriptional regulator, TetR family protein
M. thermoresistible (build 8)TH_3488-3e-2631.31% (198) PUTATIVE -
M. thermoresistible (build 8)TH_0537-1e-1836.00% (200) transcriptional regulator, TetR family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1561-1e-0527.83% (212) transcriptional regulator
M. gilvum PYR-GCKMflv_2432-1e-10789.81% (216) TetR family transcriptional regulator
M. tuberculosis H37RvRv1534-1e-0527.83% (212) transcriptional regulator
M. leprae Br4923MLBr_01070-2e-0629.29% (99) putative TetR-family transcriptional regulator
M. abscessus ATCC 19977MAB_4479-4e-0834.95% (103) TetR family transcriptional regulator
M. marinum MMMAR_4752-1e-10587.96% (216) transcriptional regulatory protein
M. avium 104MAV_1626-4e-2235.90% (195) hypothetical protein MAV_1626
M. smegmatis MC2 155MSMEG_4847-1e-10790.78% (217) transcriptional regulator, TetR family protein
M. ulcerans Agy99MUL_0323-1e-10487.50% (216) transcriptional regulatory protein
M. vanbaalenii PYR-1Mvan_4220-1e-10689.81% (216) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2432|M.gilvum_PYR-GCK          MARRSPVQSVHVFPSRAASEPPVTTPSEEPAWKQRAVERSIKTAKLRAAQ
Mvan_4220|M.vanbaalenii_PYR-1       MARRSPVQSVRVLPNRPASEPPVTSPSEEPAWKQRAVERSIKTAKLRAAQ
MSMEG_4847|M.smegmatis_MC2_155      ----------------------MTSAGEEPAWKQRAVERSIKTAKLRAAQ
TH_2023|M.thermoresistible__bu      ----------------------VTTPSEEPAWKQRAVERSIKTAKLRAAQ
MMAR_4752|M.marinum_M               ----------------------MTNPSEEPAWKQRAVERSIKTAKLRAAQ
MUL_0323|M.ulcerans_Agy99           ----------------------MTNPSEEPAWKQRAVERSIKTAKLRAAQ
Mb1561|M.bovis_AF2122/97            -------------------------MSRASARRRRAVSDEDK------SQ
Rv1534|M.tuberculosis_H37Rv         -------------------------MSRASARRRRAVSDEDK------SQ
MAV_1626|M.avium_104                ----------------------MAEPNEDVEIT-----------------
MAB_4479|M.abscessus_ATCC_1997      ------------------------MAASPGLWGGRTAAQRR-------AE
MLBr_01070|M.leprae_Br4923          ----------------------MIVVGNFTQSNYVPASRGRRSSQLSGDD
                                                                                      

Mflv_2432|M.gilvum_PYR-GCK          RVQRFLDAAQAIIIEKGSTDFTVQEVVDRSRQSLRSFYLQFDGKHELLLA
Mvan_4220|M.vanbaalenii_PYR-1       RVQRFLDAAQAIIIEKGSTDFTVQEVVDRSRQSLRSFYLQFDGKHELLLA
MSMEG_4847|M.smegmatis_MC2_155      RVQRFLDAAQAIIIEKGSTDFTVQEVVDRSRQSLRSFYLQFDGKHELLLA
TH_2023|M.thermoresistible__bu      RVQRFLDAAQAIIIEKGSTDFTVQEVVDRSRQSLRSFYLQFDGKHELLLA
MMAR_4752|M.marinum_M               RVQRFLDAAQAIIIEKGSTDFTVQEVVDRSRQSLRSFYLQFDGKHELLLA
MUL_0323|M.ulcerans_Agy99           RVQRFLDAAQAIIIEKGSTDFTVQEVVDRSRQSLRSFYLQFDGKHELLLA
Mb1561|M.bovis_AF2122/97            RRDEILAAAKIVFAHKGFHATTVADIAKQAGLAYGLIYWYFDSKDDLFHA
Rv1534|M.tuberculosis_H37Rv         RRDEILAAAKIVFAHKGFHATTVADIAKQAGLAYGLIYWYFDSKDDLFHA
MAV_1626|M.avium_104                RGDRFIKTAVAILGETGRTDFTVQEVVARSKTSLRAFYQHFSSKDELLLA
MAB_4479|M.abscessus_ATCC_1997      RRERLVGAAQEIWIEQGWAAVTMRGVCARTSLNDRYFYEDFADREDLLAA
MLBr_01070|M.leprae_Br4923          REQAILAVAERLLAERPLGDFSVDELAKGAGISRPTFYFYFPSKNAVLLS
                                    * : :: .*  :  .      ::  :   :      :*  * .:. :: :

Mflv_2432|M.gilvum_PYR-GCK          LFED-----ALSRSAEQIRAATSGQESPIDRLKVAIQLLFESSRPDPSAK
Mvan_4220|M.vanbaalenii_PYR-1       LFED-----ALSRSADQIRAATGGHEEPIERLKVAIQLLFESSRPDPAAK
MSMEG_4847|M.smegmatis_MC2_155      LFED-----ALSRSADQIRAATASHSDPLERLKVAIQLLFESSRPDPAAK
TH_2023|M.thermoresistible__bu      LFED-----ALSRSADQIRAATAGKTDPLERLKTAIELLFESSRPDPNAK
MMAR_4752|M.marinum_M               LFED-----ALSRSADQIRAATETHADPLERLKVAVELLYEASRPDPTAK
MUL_0323|M.ulcerans_Agy99           LFED-----ALSRSADQIRAATETHADPLERLKVAVELLYEASRPDPTAK
Mb1561|M.bovis_AF2122/97            LMAGEEEALRAHVAAELARVGGSTEAPLRALLQAAVQATFEFFETDKATV
Rv1534|M.tuberculosis_H37Rv         LMAGEEEALRAHVAAELARVGGSTEAPLRALLQAAVQATFEFFETDKATV
MAV_1626|M.avium_104                LFDR-----TIAQSAQTWRAETAGLDSTAALKLVIDRVSQQPESSTQDSL
MAB_4479|M.abscessus_ATCC_1997      VWDG---VRDELIAQISAIVAEDPDRPPLDTLRKTITLVVERVSGDPGWA
MLBr_01070|M.leprae_Br4923          LLDD----LNMKSRSAVEALAEQLPADPAAVWRSAITAFFEVCGTHR--A
                                    :                                       :         

Mflv_2432|M.gilvum_PYR-GCK          RPLFTDFAPRLLVSHPSEVKVAHAPLLALLTELMEEASEAGQLREGINPK
Mvan_4220|M.vanbaalenii_PYR-1       RPLFTDFAPRLLVSHPSEVKVAHAPLLALLTELMEEASAAGQLRDGINPK
MSMEG_4847|M.smegmatis_MC2_155      RPLFTDFAPRLLVSHPSEVKVAHAPLLALLTELMEEAGEAGLLREGINPK
TH_2023|M.thermoresistible__bu      RPLFTDFAPRLLVSHPEEVKVAHAPLLALLTELMEEAAAAGKLREGINPK
MMAR_4752|M.marinum_M               RPLFTDFAPRLLVSHPAEVKVAHAPLVALLTELMEAAAEAGELREDLNPR
MUL_0323|M.ulcerans_Agy99           RPLFTDFAPRLLVSHPTEVKVAHAPLVTLLTELMEAAAEAGELREDLNPR
Mb1561|M.bovis_AF2122/97            KLLFRD-AYALGGRFEEHLGGIYERFIDDIEAVVVAAQRRGEVVE--APS
Rv1534|M.tuberculosis_H37Rv         KLLFRD-AYALGGRFEEHLGGIYERFIDDIEAVVVAAQRRGEVVE--APS
MAV_1626|M.avium_104                NRALTLYNQHLAETRPREYARVLSPLHRLIRDIVGQGITEGVFNPGLDVG
MAB_4479|M.abscessus_ATCC_1997      DIIFVRHVGSAVLEQ-RRIDLLHQATAVLIAAAEPYLVKNIDRTGFRMDT
MLBr_01070|M.leprae_Br4923          VAVAGAAAKATSPEVRRLWSTVMQQWIDYNTAAIQAERKCGVAPDTIPAE
                                                                                      

Mflv_2432|M.gilvum_PYR-GCK          RMAAMTMQTVM-FVAQSSGEYDENAAHPITADEVWDFCAHGFAAG-----
Mvan_4220|M.vanbaalenii_PYR-1       RMAAMTMQTVM-FVAQSSGDVDENAANPITADEVWDFCAHGFAAV-----
MSMEG_4847|M.smegmatis_MC2_155      RMAAMTMQTVM-FVAQSSGGADESTPNPITADEVWDFVAHGFSADPPA--
TH_2023|M.thermoresistible__bu      RMAAMTMQTVM-FVAQSSGGTGDGTVHPITADEVWDFVAHGFAADD----
MMAR_4752|M.marinum_M               RIAAMTMQTVM-FIAQSSGGTDDATTHPITADEVWDFCSRGFAAS-----
MUL_0323|M.ulcerans_Agy99           RIAAMTMQTVM-FIAQSSGGTDDATTHPITADEVWDFCSRGFAAS-----
Mb1561|M.bovis_AF2122/97            RMAAYTLAALVGQLAHRRLNTDDNVTAAQVADFVVSLVLDGLRPRALAVG
Rv1534|M.tuberculosis_H37Rv         RMAAYTLAALVGQLAHRRLNTDDNVTAAQVADFVVSLVLDGLRPRALAVG
MAV_1626|M.avium_104                AAAAIVMQTMMGAQRLHWLGAELNG-TPVDAGQLYDFCSRALGIRDTDED
MAB_4479|M.abscessus_ATCC_1997      LVGIGGFSELVNAWRSGLLDVSADELIEHSTRIGATLASRYLAAG-----
MLBr_01070|M.leprae_Br4923          DLAVALQLMTERVMAATFSDEKPLIPDKKVIDTLVHIWLASIYGS-----
                                      .                                 :    :        

Mflv_2432|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4220|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4847|M.smegmatis_MC2_155      --------------------------------------------------
TH_2023|M.thermoresistible__bu      --------------------------------------------------
MMAR_4752|M.marinum_M               --------------------------------------------------
MUL_0323|M.ulcerans_Agy99           --------------------------------------------------
Mb1561|M.bovis_AF2122/97            ARGGRAART-----------------------------------------
Rv1534|M.tuberculosis_H37Rv         ARGGRAART-----------------------------------------
MAV_1626|M.avium_104                AGAPSLAELFGQIGMRPGTRNGQFAMTMPVSPAVVNTSGALQGGLIATLV
MAB_4479|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_01070|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_2432|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4220|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4847|M.smegmatis_MC2_155      --------------------------------------------------
TH_2023|M.thermoresistible__bu      --------------------------------------------------
MMAR_4752|M.marinum_M               --------------------------------------------------
MUL_0323|M.ulcerans_Agy99           --------------------------------------------------
Mb1561|M.bovis_AF2122/97            --------------------------------------------------
Rv1534|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_1626|M.avium_104                DVAGGQFGLDYLRPGTTMTTADLFVRYLRPVRQGSAFAVPRMLRSGRRAM
MAB_4479|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_01070|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_2432|M.gilvum_PYR-GCK          --------------------------------------
Mvan_4220|M.vanbaalenii_PYR-1       --------------------------------------
MSMEG_4847|M.smegmatis_MC2_155      --------------------------------------
TH_2023|M.thermoresistible__bu      --------------------------------------
MMAR_4752|M.marinum_M               --------------------------------------
MUL_0323|M.ulcerans_Agy99           --------------------------------------
Mb1561|M.bovis_AF2122/97            --------------------------------------
Rv1534|M.tuberculosis_H37Rv         --------------------------------------
MAV_1626|M.avium_104                VMQVDIFGDGDDELLATATVNFAIINGDTPSSGLPPAE
MAB_4479|M.abscessus_ATCC_1997      --------------------------------------
MLBr_01070|M.leprae_Br4923          --------------------------------------