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MSPSPSALLADHPDRIRWNAKYECADPTEAVFAPISWLGDVLQFGVPEGPVLELACGRSGTALGLAAAGR CVTAIDVSDTALVQLELEATRRELADRLTLVHADLCSWQSGDGRFALVLCRLFWHPPTFRQACEAVAPGG VVAWEAWRRPIDVARDTRRAEWCLKPGQPESELPAGFTVIRVVDTDGSEPSRRIIAQRSL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3120 | - | - | 100% (200) | hypothetical protein Rv3120 |
| M. tuberculosis H37Rv | Rv3322c | - | 1e-54 | 56.50% (200) | methyltransferase |
| M. tuberculosis H37Rv | Rv0560c | - | 1e-06 | 29.07% (172) | benzoquinone methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3351c | - | 1e-54 | 56.50% (200) | methyltransferase |
| M. gilvum PYR-GCK | Mflv_2895 | - | 1e-10 | 41.07% (112) | methyltransferase type 11 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3178 | - | 3e-08 | 35.58% (104) | hypothetical protein MAB_3178 |
| M. marinum M | MMAR_0089 | - | 5e-07 | 30.19% (106) | hypothetical protein MMAR_0089 |
| M. avium 104 | MAV_2216 | cheR | 3e-08 | 31.39% (137) | CheR methyltransferase SAM binding domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_4303 | - | 2e-11 | 42.16% (102) | methyltransferase |
| M. thermoresistible (build 8) | TH_0144 | - | 4e-07 | 35.58% (104) | methyltransferase |
| M. ulcerans Agy99 | MUL_3115 | - | 7e-07 | 29.05% (148) | methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_3615 | - | 2e-09 | 37.50% (112) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3120|M.tuberculosis_H37Rv --------------------------------------------------
Mb3351c|M.bovis_AF2122/97 --------------------------------------------------
Mflv_2895|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3615|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2216|M.avium_104 --------------------------------------------------
TH_0144|M.thermoresistible__bu --------------------------------------------------
MSMEG_4303|M.smegmatis_MC2_155 MENKPWDSIIVGGGAAGLSAALVLGRARRRVLLVDAGEQSNLPAHGIGGL
MAB_3178|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_3115|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0089|M.marinum_M --------------------------------------------------
Rv3120|M.tuberculosis_H37Rv --------------------------------------------------
Mb3351c|M.bovis_AF2122/97 --------------------------------------------------
Mflv_2895|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3615|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2216|M.avium_104 --------------------------------------------------
TH_0144|M.thermoresistible__bu --------------------------------------------------
MSMEG_4303|M.smegmatis_MC2_155 LGSDGRAPADLYAAGHAELAAYPSVQVRRGEVIAGRRGFALDLADGGHEH
MAB_3178|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_3115|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0089|M.marinum_M --------------------------------------------------
Rv3120|M.tuberculosis_H37Rv --------------------------------------------------
Mb3351c|M.bovis_AF2122/97 --------------------------------------------------
Mflv_2895|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3615|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2216|M.avium_104 --------------------------------------------------
TH_0144|M.thermoresistible__bu --------------------------------------------------
MSMEG_4303|M.smegmatis_MC2_155 ARTVLLAAGMDYLPPNIPGLGELWGRSVFHCPFCHGWEVRDAPLAVIARG
MAB_3178|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_3115|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0089|M.marinum_M --------------------------------------------------
Rv3120|M.tuberculosis_H37Rv --------------------------------------------------
Mb3351c|M.bovis_AF2122/97 --------------------------------------------------
Mflv_2895|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3615|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2216|M.avium_104 --------------------------------------------------
TH_0144|M.thermoresistible__bu --------------------------------------------------
MSMEG_4303|M.smegmatis_MC2_155 ERAVHSALLLRAWSDDIVVLTNGPDGLDDAQTEKLGAAGIPVNDASIARL
MAB_3178|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_3115|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0089|M.marinum_M --------------------------------------------------
Rv3120|M.tuberculosis_H37Rv --------------------------------------------------
Mb3351c|M.bovis_AF2122/97 --------------------------------------------------
Mflv_2895|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3615|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2216|M.avium_104 --------------------------------------------------
TH_0144|M.thermoresistible__bu --------------------------------------------------
MSMEG_4303|M.smegmatis_MC2_155 VAHDGELVAVEFTDGTRLSRRGALVATTLHQRSPLAAQLGAIGAPTPLAG
MAB_3178|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_3115|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0089|M.marinum_M --------------------------------------------------
Rv3120|M.tuberculosis_H37Rv --------------------------------------------------
Mb3351c|M.bovis_AF2122/97 --------------------------------------------------
Mflv_2895|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3615|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2216|M.avium_104 --------------------------------------------------
TH_0144|M.thermoresistible__bu --------------------------------------------------
MSMEG_4303|M.smegmatis_MC2_155 DAVVVDTFGRTTVPGLFAAGDLTGNLPQVATAVAAGSQTAAAIVQHLLAE
MAB_3178|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_3115|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0089|M.marinum_M --------------------------------------------------
Rv3120|M.tuberculosis_H37Rv --MSPSPSALLADHPDRIRWNAKYECADPTEAVFAPI-SWLGDVLQFGVP
Mb3351c|M.bovis_AF2122/97 --MSVQTDPALREHPNRVDWNARYERAGSAHAPFAPV-PWLADVLRAGVP
Mflv_2895|M.gilvum_PYR-GCK -----------MT-DVKQHWEERYSQRDRIWSGHVN--RWLAEVAAP-LK
Mvan_3615|M.vanbaalenii_PYR-1 -----------MTSEVKQHWEERYAERDRIWSGRVN--RWLAEVAAS-EK
MAV_2216|M.avium_104 ------MDTSCEPGEAGRFWEERYRGAERVWSGRVN--PRLAELAAD-LP
TH_0144|M.thermoresistible__bu -----------------------------MWSGRVN--ARLAEVAGE-LP
MSMEG_4303|M.smegmatis_MC2_155 DIGLPTPPWPTEGLSPAEYWERHYGEREQIWSGRVN--PQLEKVASD-LP
MAB_3178|M.abscessus_ATCC_1997 ------MHDHNNPPSDEKSWDEFYQSHDALWSGNAN--PQLVAEISS-LP
MUL_3115|M.ulcerans_Agy99 --------MARVAESDRRRWDRRYASLGPAAVSAVRPPALLQAHLKLVPA
MMAR_0089|M.marinum_M ------------MTEPRMDWDSAYRQDVRPPWSIGAPQPELAALIEGGKV
*
Rv3120|M.tuberculosis_H37Rv EGPVLELACGRSGTALGLAAAGRCVTAIDVSDTALVQLELEATRR--ELA
Mb3351c|M.bovis_AF2122/97 DGPVLELASGRSGTALALAAHGRQVTAIDVSDVALLQLDSEAVRR--GVA
Mflv_2895|M.gilvum_PYR-GCK PGRALDLGCGEGGDTLWLAEHGWEVVGVDISDTALRRAAEEADKR--GLA
Mvan_3615|M.vanbaalenii_PYR-1 PGHALDLGCGEGGDTVWLAEHGWQVLGVDISDTALGRAAAEAATR--GLT
MAV_2216|M.avium_104 AGRALDLGCGEGADALWLAQRGWTVLAVDISATALRRAAEAAASR--KLL
TH_0144|M.thermoresistible__bu PGRALDVGCGEGADAMWLAERGWQVTAVDISQTALDRAAAEAASR--GLT
MSMEG_4303|M.smegmatis_MC2_155 AGHALDLGCGEGGDAVWLAERGWRVTAVDISHTALSRAAAEAGRR--GVA
MAB_3178|M.abscessus_ATCC_1997 PRTALDAGCGEGGDAIWLAQHGWQVTGMDFAHTALRRAADNAVKVDPELA
MUL_3115|M.ulcerans_Agy99 AGRALDLGCGQGLGAVWLARRGLDVLGLDISPVAIAQARDLAERS--GVS
MMAR_0089|M.marinum_M RSEVLDAGCGEAELSLALAAQGYSVVGLDASATAIATASAAAAER---GL
.*: ..*.. :: ** * * .:* : .*: *
Rv3120|M.tuberculosis_H37Rv DRLTLVHADLCSWQSGDGRFALVLCRLFW------HPPTFRQACEAVAPG
Mb3351c|M.bovis_AF2122/97 DRLNLVQADLGCWEPGETRFALVLSRLFW------DAAIFHRACEAVMPG
Mflv_2895|M.gilvum_PYR-GCK DRVQLRQTDLSASFP-DGVFDLVSAQFLQSMVHLDRERIFAAAARAVAPG
Mvan_3615|M.vanbaalenii_PYR-1 DRVRFVQMNLSEAFP-EGVFDLVSAQFLQSMVHLDRERIFAAAARAVAPG
MAV_2216|M.avium_104 ARIDFQRHDLNESFP-EGMFDLISAQYFHSPVHLDRDAVLRRAATRVKPG
TH_0144|M.thermoresistible__bu --IDFQRHELPATFP-DGQFELVSAHFLHSEVELDRVRILRRAAEAVVPG
MSMEG_4303|M.smegmatis_MC2_155 DRITFERHDLSESFP-DGEFDLVSAQFLHSTVRLERPRILSTAARAIRPG
MAB_3178|M.abscessus_ATCC_1997 NRISWTQADLTAWQP-NRQFDLVTSHFMHLPTNL-REPVFAALAAAVAPG
MUL_3115|M.ulcerans_Agy99 ARCRFDVVDLDDGLPDGPPVDLIVCHNFR------DRRLDAAIIERLAPG
MMAR_0089|M.marinum_M TTASFAAADVTAFDGYDGRFNTVMDSGLLHVAG---PRELVRGERESFIG
:: . : : *
Rv3120|M.tuberculosis_H37Rv GVVAWEAWRRPIDVARDTRRAEWCLKPGQPES---ELPAGFTVIRVV---
Mb3351c|M.bovis_AF2122/97 GVLAWESLALSGAEAG-TASAKRRVKPGEPAC---LLPADFTVVHEG---
Mflv_2895|M.gilvum_PYR-GCK GVLIVVDHAAAPPWAPPEVHEHRFSTVDEVLATIDLGEGSWERLRADVVE
Mvan_3615|M.vanbaalenii_PYR-1 GVLVIVDHGAAPSWAPEHIREHVFPGVEEVLATVDLGDGQWRRVRADRVE
MAV_2216|M.avium_104 GVLLIVDHGAAPPWAQHDGHH--FPGVEEVLGSLRLDPDGWTRLRAEAAG
TH_0144|M.thermoresistible__bu GLLLIVDHGAPPPWAPDHVHEFEFPSAQEVVESLQLPEGQWELLRAEPVK
MSMEG_4303|M.smegmatis_MC2_155 GHLVIVDHGKMPPNATRVPHDHPFPSAEEVLAGLDLPASEWERVRVEAVH
MAB_3178|M.abscessus_ATCC_1997 GTLLIVGHHPSDMQAAIGRPDLPDWYFTAEDIADTLNPKEWTIIVAESRS
MUL_3115|M.ulcerans_Agy99 GLVALVALSEVGAAAGTYRAAPGELST---------AFAELDPIAAG---
MMAR_0089|M.marinum_M GYRRQHSGQAVGSPAMNAADDGCTRASSRR--------------------
* *
Rv3120|M.tuberculosis_H37Rv ------DTD-GSEPSRRIIAQRSL------
Mb3351c|M.bovis_AF2122/97 ------QGNCDSAPSRIMIARRSPLPGA--
Mflv_2895|M.gilvum_PYR-GCK RDAIGPDGEAGVLRDNLIVVRRCA------
Mvan_3615|M.vanbaalenii_PYR-1 RDATGPDGQQAVLIDNLIVLRRL-------
MAV_2216|M.avium_104 REMTGPNGEVGTLMDNIMMLRRTEQAYAAS
TH_0144|M.thermoresistible__bu RDAVGPDGQQGTLIDNVIMLRRR-------
MSMEG_4303|M.smegmatis_MC2_155 REATGPDGQPMPMVDNVMVLRRTS------
MAB_3178|M.abscessus_ATCC_1997 RKFTR-DDEEFDIADTVLRAERKPTTESA-
MUL_3115|M.ulcerans_Agy99 -----------EGDGRAWLLARA-------
MMAR_0089|M.marinum_M ------------------------------