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MSVQTDPALREHPNRVDWNARYERAGSAHAPFAPVPWLADVLRAGVPDGPVLELASGRSGTALALAAHGR QVTAIDVSDVALLQLDSEAVRRGVADRLNLVQADLGCWEPGETRFALVLSRLFWDAAIFHRACEAVMPGG VLAWESLALSGAEAGTASAKRRVKPGEPACLLPADFTVVHEGQGNCDSAPSRIMIARRSPLPGA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3351c | - | - | 100% (204) | methyltransferase |
| M. bovis AF2122 / 97 | Mb3725 | - | 5e-07 | 30.65% (124) | hypothetical protein Mb3725 |
| M. bovis AF2122 / 97 | Mb0575c | - | 6e-06 | 26.32% (152) | benzoquinone methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2895 | - | 2e-13 | 38.81% (134) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv3322c | - | 1e-117 | 100.00% (204) | methyltransferase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3178 | - | 2e-08 | 30.30% (132) | hypothetical protein MAB_3178 |
| M. marinum M | MMAR_2640 | - | 4e-10 | 31.21% (173) | methyltransferase |
| M. avium 104 | MAV_2957 | - | 2e-09 | 32.91% (158) | thiopurine S-methyltransferase (tpmt) superfamily protein |
| M. smegmatis MC2 155 | MSMEG_4544 | - | 3e-10 | 33.56% (149) | methyltransferase small subunit |
| M. thermoresistible (build 8) | TH_1722 | - | 1e-07 | 28.57% (133) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3115 | - | 2e-10 | 30.64% (173) | methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_3615 | - | 8e-12 | 40.18% (112) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3351c|M.bovis_AF2122/97 ---------------------------MSVQTDPALREHPNRVDWNARYE
Rv3322c|M.tuberculosis_H37Rv ---------------------------MSVQTDPALREHPNRVDWNARYE
MMAR_2640|M.marinum_M MSRTAERADRLSIRYPVCSPTAQVRRSCRGRRMVARVAESDRRRWDRRYA
MUL_3115|M.ulcerans_Agy99 ---------------------------------MARVAESDRRRWDRRYA
MAV_2957|M.avium_104 ------------------------------------MGEADRHRWDERYA
MSMEG_4544|M.smegmatis_MC2_155 ------------------------------------MSEHDRARWDAAYT
Mflv_2895|M.gilvum_PYR-GCK ------------------------------------MT-DVKQHWEERYS
Mvan_3615|M.vanbaalenii_PYR-1 ------------------------------------MTSEVKQHWEERYA
MAB_3178|M.abscessus_ATCC_1997 -------------------------------MHDHNNPPSDEKSWDEFYQ
TH_1722|M.thermoresistible__bu ----------------------------MATEDPGTGDPTDTIDWDSVYR
*: *
Mb3351c|M.bovis_AF2122/97 R----AGS--AHAPFAPVPWLADVLRAGVPDGPVLELASGRSGTALALAA
Rv3322c|M.tuberculosis_H37Rv R----AGS--AHAPFAPVPWLADVLRAGVPDGPVLELASGRSGTALALAA
MMAR_2640|M.marinum_M S----LGP-AAVSAARPPALLQAHLKLVPTAGRALDLGCGQGLGAVWLAR
MUL_3115|M.ulcerans_Agy99 S----LGP-AAVSAVRPPALLQAHLKLVPAAGRALDLGCGQGLGAVWLAR
MAV_2957|M.avium_104 A----NGP-PPLSSVAPPGVFARHADVFPAAGRALDLACGQGTAAVWLAL
MSMEG_4544|M.smegmatis_MC2_155 DRP--LGAGLPDGPAGPPRAFAGHVDEFPTAGSALDVACGSGENSVWLAR
Mflv_2895|M.gilvum_PYR-GCK Q-------RDRIWSGHVNRWLAEVAAPLKP-GRALDLGCGEGGDTLWLAE
Mvan_3615|M.vanbaalenii_PYR-1 E-------RDRIWSGRVNRWLAEVAASEKP-GHALDLGCGEGGDTVWLAE
MAB_3178|M.abscessus_ATCC_1997 S-------HDALWSGNANPQLVAEISSLPP-RTALDAGCGEGGDAIWLAQ
TH_1722|M.thermoresistible__bu QEAPGFDGPPPWNIGEPQPELAALHRAGAFRSDVLDAGCGHAEISMALAA
: .*: ..* . :: **
Mb3351c|M.bovis_AF2122/97 HGRQVTAIDVSDVALLQLDSEAVRRG--VADRLNLVQADLGCWE-PGETR
Rv3322c|M.tuberculosis_H37Rv HGRQVTAIDVSDVALLQLDSEAVRRG--VADRLNLVQADLGCWE-PGETR
MMAR_2640|M.marinum_M RGLDVLGLDISPVAIAQARDLAERSG--VSARCCFDVVDLDDGL-PDGPP
MUL_3115|M.ulcerans_Agy99 RGLDVLGLDISPVAIAQARDLAERSG--VSARCRFDVVDLDDGL-PDGPP
MAV_2957|M.avium_104 RGLRVLGLDVSPVAIGQARDLARRAG--VGERCRFDVADLDRGL-PVGPP
MSMEG_4544|M.smegmatis_MC2_155 RGLHVWGIDVSPVAITQATQFAARNG--VAQRCRFDVVDLDDGL-PDGPP
Mflv_2895|M.gilvum_PYR-GCK HGWEVVGVDISDTALRRAAEEADKRG--LADRVQLRQTDLSASF-PDGV-
Mvan_3615|M.vanbaalenii_PYR-1 HGWQVLGVDISDTALGRAAAEAATRG--LTDRVRFVQMNLSEAF-PEGV-
MAB_3178|M.abscessus_ATCC_1997 HGWQVTGMDFAHTALRRAADNAVKVDPELANRISWTQADLTAWQ-PNRQ-
TH_1722|M.thermoresistible__bu DGYTVVGIDLSPTAIAAANRTAQERG---LATASFVQGDITDFGGYDGRF
* * .:*.: .*: * . ::
Mb3351c|M.bovis_AF2122/97 FALVLSRLFW------DAAIFHRACEAVMPGG----VLAWESLALSGAEA
Rv3322c|M.tuberculosis_H37Rv FALVLSRLFW------DAAIFHRACEAVMPGG----VLAWESLALSGAEA
MMAR_2640|M.marinum_M VDVIVCHNFR------DRRLDAAIIDRLAPGG----LVALVALSEVGAAA
MUL_3115|M.ulcerans_Agy99 VDLIVCHNFR------DRRLDAAIIERLAPGG----LVALVALSEVGAAA
MAV_2957|M.avium_104 ADVIVCCKFR------DRRLDRAIVERLAPGG----LLAIAVLSEVGAGP
MSMEG_4544|M.smegmatis_MC2_155 VDVVLCHRFR------DPRLYEALRARLAPGG----LLAICVLSEVGAEA
Mflv_2895|M.gilvum_PYR-GCK FDLVSAQFLQSMVHLDRERIFAAAARAVAPGG----VLIVVDHAAAPPWA
Mvan_3615|M.vanbaalenii_PYR-1 FDLVSAQFLQSMVHLDRERIFAAAARAVAPGG----VLVIVDHGAAPSWA
MAB_3178|M.abscessus_ATCC_1997 FDLVTSHFMHLPTNL-REPVFAALAAAVAPGG----TLLIVGHHPSDMQA
TH_1722|M.thermoresistible__bu NTIIDSTLFHSIPVQARDGYLRSIHRAAAPGARYFALVFAKGAFPEEMEQ
:: . : **. :
Mb3351c|M.bovis_AF2122/97 GT------------ASAKRRVKPGEPACLLPADFTVVHE------GQGNC
Rv3322c|M.tuberculosis_H37Rv GT------------ASAKRRVKPGEPACLLPADFTVVHE------GQGNC
MMAR_2640|M.marinum_M G----------------TYRAAPGELSAAF-AELDPIAA------GEGDG
MUL_3115|M.ulcerans_Agy99 G----------------TYRAAPGELSTAF-AELDPIAA------GEGDG
MAV_2957|M.avium_104 G----------------PFRAAPGELTAAF-ADLQPIAA------GEADG
MSMEG_4544|M.smegmatis_MC2_155 G----------------RFRAPAGELRAHF-GALQVIAE------NERDG
Mflv_2895|M.gilvum_PYR-GCK PPEVHEHRFSTVDEVLATIDLGEGSWERLRADVVERDAI------GPDGE
Mvan_3615|M.vanbaalenii_PYR-1 PEHIREHVFPGVEEVLATVDLGDGQWRRVRADRVERDAT------GPDGQ
MAB_3178|M.abscessus_ATCC_1997 AIGRPDLPDWYFTAEDIADTLNPKEWTIIVAESRSRKFT------RDDEE
TH_1722|M.thermoresistible__bu GPGPNPVDEDELREAVSKYWEIDEIRPAFIHANMPPDVPGVESFDTDEKG
Mb3351c|M.bovis_AF2122/97 DSAPSRIMIARRSPLPGA----
Rv3322c|M.tuberculosis_H37Rv DSAPSRIMIARRSPLPGA----
MMAR_2640|M.marinum_M R----AWLLARA----------
MUL_3115|M.ulcerans_Agy99 R----AWLLARA----------
MAV_2957|M.avium_104 Q----AWLLARASQSEPMVERR
MSMEG_4544|M.smegmatis_MC2_155 E----AWLLAR-----------
Mflv_2895|M.gilvum_PYR-GCK AGVLRDNLIVVRRCA-------
Mvan_3615|M.vanbaalenii_PYR-1 QAVLIDNLIVLRRL--------
MAB_3178|M.abscessus_ATCC_1997 FDIADTVLRAERKPTTESA---
TH_1722|M.thermoresistible__bu RTKLPAFLLSAHKA--------
: