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MHDHNNPPSDEKSWDEFYQSHDALWSGNANPQLVAEISSLPPRTALDAGCGEGGDAIWLAQHGWQVTGMD FAHTALRRAADNAVKVDPELANRISWTQADLTAWQPNRQFDLVTSHFMHLPTNLREPVFAALAAAVAPGG TLLIVGHHPSDMQAAIGRPDLPDWYFTAEDIADTLNPKEWTIIVAESRSRKFTRDDEEFDIADTVLRAER KPTTESA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3178 | - | - | 100% (217) | hypothetical protein MAB_3178 |
| M. abscessus ATCC 19977 | MAB_4799c | - | 5e-09 | 33.33% (138) | hypothetical protein MAB_4799c |
| M. abscessus ATCC 19977 | MAB_2834c | - | 8e-08 | 29.50% (139) | hypothetical protein MAB_2834c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1412c | - | 1e-08 | 28.82% (170) | putative transferase |
| M. gilvum PYR-GCK | Mflv_2895 | - | 8e-33 | 49.28% (138) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv1377c | - | 1e-08 | 28.82% (170) | putative transferase |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_2640 | - | 4e-09 | 31.82% (154) | methyltransferase |
| M. avium 104 | MAV_2216 | cheR | 4e-30 | 36.54% (208) | CheR methyltransferase SAM binding domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_4303 | - | 1e-31 | 37.86% (206) | methyltransferase |
| M. thermoresistible (build 8) | TH_0144 | - | 4e-26 | 36.32% (201) | methyltransferase |
| M. ulcerans Agy99 | MUL_3115 | - | 1e-09 | 33.12% (154) | methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_3615 | - | 2e-29 | 47.10% (138) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1412c|M.bovis_AF2122/97 --------------------------------------------------
Rv1377c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_2895|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3615|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2216|M.avium_104 --------------------------------------------------
TH_0144|M.thermoresistible__bu --------------------------------------------------
MSMEG_4303|M.smegmatis_MC2_155 MENKPWDSIIVGGGAAGLSAALVLGRARRRVLLVDAGEQSNLPAHGIGGL
MAB_3178|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2640|M.marinum_M --------------------------------------------------
MUL_3115|M.ulcerans_Agy99 --------------------------------------------------
Mb1412c|M.bovis_AF2122/97 --------------------------------------------------
Rv1377c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_2895|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3615|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2216|M.avium_104 --------------------------------------------------
TH_0144|M.thermoresistible__bu --------------------------------------------------
MSMEG_4303|M.smegmatis_MC2_155 LGSDGRAPADLYAAGHAELAAYPSVQVRRGEVIAGRRGFALDLADGGHEH
MAB_3178|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2640|M.marinum_M --------------------------------------------------
MUL_3115|M.ulcerans_Agy99 --------------------------------------------------
Mb1412c|M.bovis_AF2122/97 --------------------------------------------------
Rv1377c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_2895|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3615|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2216|M.avium_104 --------------------------------------------------
TH_0144|M.thermoresistible__bu --------------------------------------------------
MSMEG_4303|M.smegmatis_MC2_155 ARTVLLAAGMDYLPPNIPGLGELWGRSVFHCPFCHGWEVRDAPLAVIARG
MAB_3178|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2640|M.marinum_M --------------------------------------------------
MUL_3115|M.ulcerans_Agy99 --------------------------------------------------
Mb1412c|M.bovis_AF2122/97 --------------------------------------------------
Rv1377c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_2895|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3615|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2216|M.avium_104 --------------------------------------------------
TH_0144|M.thermoresistible__bu --------------------------------------------------
MSMEG_4303|M.smegmatis_MC2_155 ERAVHSALLLRAWSDDIVVLTNGPDGLDDAQTEKLGAAGIPVNDASIARL
MAB_3178|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2640|M.marinum_M --------------------------------------------------
MUL_3115|M.ulcerans_Agy99 --------------------------------------------------
Mb1412c|M.bovis_AF2122/97 --------------------------------------------------
Rv1377c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_2895|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3615|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2216|M.avium_104 --------------------------------------------------
TH_0144|M.thermoresistible__bu --------------------------------------------------
MSMEG_4303|M.smegmatis_MC2_155 VAHDGELVAVEFTDGTRLSRRGALVATTLHQRSPLAAQLGAIGAPTPLAG
MAB_3178|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2640|M.marinum_M --------------------------------------------------
MUL_3115|M.ulcerans_Agy99 --------------------------------------------------
Mb1412c|M.bovis_AF2122/97 --------------------------------------------------
Rv1377c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_2895|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3615|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2216|M.avium_104 --------------------------------------------------
TH_0144|M.thermoresistible__bu --------------------------------------------------
MSMEG_4303|M.smegmatis_MC2_155 DAVVVDTFGRTTVPGLFAAGDLTGNLPQVATAVAAGSQTAAAIVQHLLAE
MAB_3178|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2640|M.marinum_M -------------------------MSRTAERADRLSIRYPVCSPTAQVR
MUL_3115|M.ulcerans_Agy99 --------------------------------------------------
Mb1412c|M.bovis_AF2122/97 ----MPGIDFDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWV-
Rv1377c|M.tuberculosis_H37Rv ----MPGIDFDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWV-
Mflv_2895|M.gilvum_PYR-GCK -----------MT-DVKQHWEERYSQRDRIWSGHVN--RWLAEVAAPLK-
Mvan_3615|M.vanbaalenii_PYR-1 -----------MTSEVKQHWEERYAERDRIWSGRVN--RWLAEVAASEK-
MAV_2216|M.avium_104 ------MDTSCEPGEAGRFWEERYRGAERVWSGRVN--PRLAELAADLP-
TH_0144|M.thermoresistible__bu -----------------------------MWSGRVN--ARLAEVAGELP-
MSMEG_4303|M.smegmatis_MC2_155 DIGLPTPPWPTEGLSPAEYWERHYGEREQIWSGRVN--PQLEKVASDLP-
MAB_3178|M.abscessus_ATCC_1997 ------MHDHNNPPSDEKSWDEFYQSHDALWSGNAN--PQLVAEISSLP-
MMAR_2640|M.marinum_M RSCRGRRMVARVAESDRRRWDRRYASLGPAAVSAARPPALLQAHLKLVPT
MUL_3115|M.ulcerans_Agy99 --------MARVAESDRRRWDRRYASLGPAAVSAVRPPALLQAHLKLVPA
. :
Mb1412c|M.bovis_AF2122/97 HGDVLDIGCGLGDNAIYLARNGYQVTGLDISPTALTTAKRRASDA--GVD
Rv1377c|M.tuberculosis_H37Rv HGDVLDIGCGLGDNAIYLARNGYQVTGLDISPTALTTAKRRASDA--GVD
Mflv_2895|M.gilvum_PYR-GCK PGRALDLGCGEGGDTLWLAEHGWEVVGVDISDTALRRAAEEADKR--GLA
Mvan_3615|M.vanbaalenii_PYR-1 PGHALDLGCGEGGDTVWLAEHGWQVLGVDISDTALGRAAAEAATR--GLT
MAV_2216|M.avium_104 AGRALDLGCGEGADALWLAQRGWTVLAVDISATALRRAAEAAASR--KLL
TH_0144|M.thermoresistible__bu PGRALDVGCGEGADAMWLAERGWQVTAVDISQTALDRAAAEAASR--GLT
MSMEG_4303|M.smegmatis_MC2_155 AGHALDLGCGEGGDAVWLAERGWRVTAVDISHTALSRAAAEAGRR--GVA
MAB_3178|M.abscessus_ATCC_1997 PRTALDAGCGEGGDAIWLAQHGWQVTGMDFAHTALRRAADNAVKVDPELA
MMAR_2640|M.marinum_M AGRALDLGCGQGLGAVWLARRGLDVLGLDISPVAIAQARDLAERS--GVS
MUL_3115|M.ulcerans_Agy99 AGRALDLGCGQGLGAVWLARRGLDVLGLDISPVAIAQARDLAERS--GVS
.** *** * .:::**..* * .:*:: .*: * * :
Mb1412c|M.bovis_AF2122/97 VKFAVGDATKLTGYTGAF-DTVIDCGMFHCLDDDGKRSYAASVHRATRPG
Rv1377c|M.tuberculosis_H37Rv VKFAVGDATKLTGYTGAF-DTVIDCGMFHCLDDDGKRSYAASVHRATRPG
Mflv_2895|M.gilvum_PYR-GCK DRVQLRQTDLSASFPDGV-FDLVSAQFLQSMVHLDRERIFAAAARAVAPG
Mvan_3615|M.vanbaalenii_PYR-1 DRVRFVQMNLSEAFPEGV-FDLVSAQFLQSMVHLDRERIFAAAARAVAPG
MAV_2216|M.avium_104 ARIDFQRHDLNESFPEGM-FDLISAQYFHSPVHLDRDAVLRRAATRVKPG
TH_0144|M.thermoresistible__bu --IDFQRHELPATFPDGQ-FELVSAHFLHSEVELDRVRILRRAAEAVVPG
MSMEG_4303|M.smegmatis_MC2_155 DRITFERHDLSESFPDGE-FDLVSAQFLHSTVRLERPRILSTAARAIRPG
MAB_3178|M.abscessus_ATCC_1997 NRISWTQADLTAWQPNRQ-FDLVTSHFMHLPTNL-REPVFAALAAAVAPG
MMAR_2640|M.marinum_M ARCCFDVVDLDDGLPDGPPVDVIVCHNFR------DRRLDAAIIDRLAPG
MUL_3115|M.ulcerans_Agy99 ARCRFDVVDLDDGLPDGPPVDLIVCHNFR------DRRLDAAIIERLAPG
. :: . :: **
Mb1412c|M.bovis_AF2122/97 ATLLLSCFSNAMPPD----EEWPRSTVSEQTLRDVLGGAGWDIESLEPAT
Rv1377c|M.tuberculosis_H37Rv ATLLLSCFSNAMPPD----EEWPRSTVSEQTLRDVLGGAGWDIESLEPAT
Mflv_2895|M.gilvum_PYR-GCK GVLIVVDHAAAPPWAPPEVHEHRFSTVDEVLATIDLGEGSWERLRADVVE
Mvan_3615|M.vanbaalenii_PYR-1 GVLVIVDHGAAPSWAPEHIREHVFPGVEEVLATVDLGDGQWRRVRADRVE
MAV_2216|M.avium_104 GVLLIVDHGAAPPWAQHDGHH--FPGVEEVLGSLRLDPDGWTRLRAEAAG
TH_0144|M.thermoresistible__bu GLLLIVDHGAPPPWAPDHVHEFEFPSAQEVVESLQLPEGQWELLRAEPVK
MSMEG_4303|M.smegmatis_MC2_155 GHLVIVDHGKMPPNATRVPHDHPFPSAEEVLAGLDLPASEWERVRVEAVH
MAB_3178|M.abscessus_ATCC_1997 GTLLIVGHHPSDMQAAIGRPDLPDWYFTAEDIADTLNPKEWTIIVAESRS
MMAR_2640|M.marinum_M GLVALVALS----------------EVGAAAGTYRAAPGELSAAFAELDP
MUL_3115|M.ulcerans_Agy99 GLVALVALS----------------EVGAAAGTYRAAPGELSTAFAELDP
. : : :
Mb1412c|M.bovis_AF2122/97 VRRELDGTEVEMAFWNVRAQRRGS------
Rv1377c|M.tuberculosis_H37Rv VRRELDGTEVEMAFWNVRAQRRGS------
Mflv_2895|M.gilvum_PYR-GCK RDAIGPDGEAGVLRDNLIVVRRCA------
Mvan_3615|M.vanbaalenii_PYR-1 RDATGPDGQQAVLIDNLIVLRRL-------
MAV_2216|M.avium_104 REMTGPNGEVGTLMDNIMMLRRTEQAYAAS
TH_0144|M.thermoresistible__bu RDAVGPDGQQGTLIDNVIMLRRR-------
MSMEG_4303|M.smegmatis_MC2_155 REATGPDGQPMPMVDNVMVLRRTS------
MAB_3178|M.abscessus_ATCC_1997 RKFTR-DDEEFDIADTVLRAERKPTTESA-
MMAR_2640|M.marinum_M IAAGEGDGRAWLLARA--------------
MUL_3115|M.ulcerans_Agy99 IAAGEGDGRAWLLARA--------------
. .