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TEKLSTGTKTLLMARVDRAEELWQTELDQTIAAIPWLRASMAHLIALNDGTLQRDASDSFVAAFDRASDA VMCALDLQLAPLEPFALCIGVHAVEHTDSADSDGAARLRDIARGGQTLISAAAAALVSARMPAHAALTPL RDRVRHEPVYQLNHPGLRTEADEVPHLPYGRVVR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0545 | - | - | 100% (175) | transcriptional regulator, LuxR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0915c | - | 2e-24 | 43.98% (166) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv0891c | - | 2e-24 | 43.98% (166) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_01753 | - | 2e-17 | 36.63% (172) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2962 | - | 4e-27 | 42.61% (176) | transcriptional regulatory protein |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2743 | - | 1e-09 | 29.68% (155) | LuxR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5928 | - | 5e-25 | 41.71% (175) | regulatory protein, LuxR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0915c|M.bovis_AF2122/97 MLFNAVHNSLPPNIDIDHAILRGEDHPPTCAKCVARGRISALGSLDLRYH
Rv0891c|M.tuberculosis_H37Rv MLFNAVHNSLPPNIDIDHAILRGEDHPPTCAKCVARVRISALGSLDLRYH
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2962|M.marinum_M --------------------------------------------------
Mvan_5928|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01753|M.leprae_Br4923 --------------------------------------------------
MUL_2743|M.ulcerans_Agy99 --------------------------------------------------
Mb0915c|M.bovis_AF2122/97 SLRCYAAPPDVGRCEFVPPRRRVLIANQGLDVSRLPPTG-----------
Rv0891c|M.tuberculosis_H37Rv SLRCYAAPPDVGRCEFVPPRRRVLIANQGLDVSRLPPTG-----------
MSMEG_0545|M.smegmatis_MC2_155 -------------------------------MTEKLSTG-----------
MMAR_2962|M.marinum_M -------------------------------MDELLLTD-----------
Mvan_5928|M.vanbaalenii_PYR-1 -------------------------------MSELVPTG-----------
MLBr_01753|M.leprae_Br4923 -------------------------MYSLGEMQKPVPVGADYLASCLVAR
MUL_2743|M.ulcerans_Agy99 --------------------------------------------------
Mb0915c|M.bovis_AF2122/97 --------------TVTLLLADVEESTHLWQMCPEDMATAIAHLDHTVSE
Rv0891c|M.tuberculosis_H37Rv --------------TVTLLLADVEESTHLWQMCPEDMATAIAHLDHTVSE
MSMEG_0545|M.smegmatis_MC2_155 --------------TKTLLMARVDRAEELWQTELDQTIAAIPWLRASMAH
MMAR_2962|M.marinum_M --------------TVTLLSADIEDSARLRQTQPTELSAALERLDQILTD
Mvan_5928|M.vanbaalenii_PYR-1 --------------TVTLLLADVQGSTQLWETQPETMTAAVAQLDRTLTD
MLBr_01753|M.leprae_Br4923 LRSTDVPTDLHRGCTVTLFLGDVEGLAELSETQPDEAADAIARLDCVVSE
MUL_2743|M.ulcerans_Agy99 ---------------MTFLFTDVEGSTRLWESDPDRMRAALAAHDAVLTR
*:: :: .* : *: ::
Mb0915c|M.bovis_AF2122/97 AITNHGGVQPVKRYEGDSFVAAFTRASDAAACALDLQRTSLAPIRLRIGL
Rv0891c|M.tuberculosis_H37Rv AITNHGGVQPVKRYEGDSFVAAFTRASDAAACALDLQRTSLAPIRLRIGL
MSMEG_0545|M.smegmatis_MC2_155 LIALNDG--TLQRDASDSFVAAFDRASDAVMCALDLQLAPLEPFALCIGV
MMAR_2962|M.marinum_M AVSAYGGVRAVEQSPGESLVVAFGRAQDAVECALQLQQAPLAPIRLCIGI
Mvan_5928|M.vanbaalenii_PYR-1 LVSDHDGVRPVEQGEGDSFVVAFTRASDAVACALALQRAPLAPIRLRIGV
MLBr_01753|M.leprae_Br4923 AVAAHGGVQQVVQGVRGNFLATFARASDATACALDLQLAPIVPVRFRIAL
MUL_2743|M.ulcerans_Agy99 TIQTHRG--WLFKHTGDGVCAAFASPRSAVDAAVDAQRALELPVRMGLAT
: * : : .. .:* . .*. .*: * : *. : :.
Mb0915c|M.bovis_AF2122/97 HTGEVQLRDE--LYVGPTINRTARLRDLAHGGQVVLSAATGDLVTGRLPA
Rv0891c|M.tuberculosis_H37Rv HTGEVQLRDE--LYVGPTINRTARLRDLAHGGQVVLSAATGDLVTGRLPA
MSMEG_0545|M.smegmatis_MC2_155 HA--VEHTDS--ADS----DGAARLRDIARGGQTLISAAAAALVSARMPA
MMAR_2962|M.marinum_M HTGEVAQPRDDGTYVGPTIDRTARLRDLARGGQTLLSAATKDIVINQLPE
Mvan_5928|M.vanbaalenii_PYR-1 HTGEVR-LRDEGNYVGPTINRTARLRELAHGGQTVLSGTTSDLVADLLPD
MLBr_01753|M.leprae_Br4923 HTGEVQISNDDVNNVVFMMVQAAGLLDLACGGQTVLSSITGDLVVDGLPA
MUL_2743|M.ulcerans_Agy99 GEAEPHDADY----FGAVLNRAARVMATGHGGQILLTDSTANLISG----
:* : . *** ::: : ::
Mb0915c|M.bovis_AF2122/97 DAWLVDLGRHPLRGLPRPEWVMQLCHPDIREKFPPLRTAKSSPTSILPAQ
Rv0891c|M.tuberculosis_H37Rv DAWLVDLGRHPLRGLPRPEWVMQLCHPDIREKFPPLRTAKSSPTSILPAQ
MSMEG_0545|M.smegmatis_MC2_155 HAALT-----PLRDRVRHEPVYQLNHPGLRT--------EADEVPHLP--
MMAR_2962|M.marinum_M QAWLTDRGLAPLRDLIHFERVAQLCHPNLRNEFPPLCVTKSPAASGLPVH
Mvan_5928|M.vanbaalenii_PYR-1 GGWLSDLGTHRLRDLPRPERVVQLCHADLSNEFPPLRAREEIGVQRLPAQ
MLBr_01753|M.leprae_Br4923 DTWLVDLGSHLLRDLARPVRVMQLCHRNLRRNLHELGIRTVPGGPSLPVP
MUL_2743|M.ulcerans_Agy99 -VDLLDLGSRRLRDLPAPVRVFQVRAPGLRTDFPALRAPDTSPG-NLRPA
* **. * *: .: *
Mb0915c|M.bovis_AF2122/97 FTTFVGRRAQIS--------------------------------------
Rv0891c|M.tuberculosis_H37Rv FTTFVGRRAQIS--------------------------------------
MSMEG_0545|M.smegmatis_MC2_155 ----YGRVVR----------------------------------------
MMAR_2962|M.marinum_M LTSFVGRGRELAEVHGLVVENRLVTLIGSGGVGKSRLAEQVVAQLAAQFV
Mvan_5928|M.vanbaalenii_PYR-1 LTSFVGRVDDMAQVRGLMDANRLVTLTGAGGVGKTRLATQVAVAVVEGYP
MLBr_01753|M.leprae_Br4923 LTTFVGRAAQIKELQELLTEKRLLTLVGPGGVGKTRLALQVVARVADEFS
MUL_2743|M.ulcerans_Agy99 LTSFVARAAEIGQVQTALQVHRLVTLTGVGGVGKTRLALEVATRVADEFP
.*
Mb0915c|M.bovis_AF2122/97 --------------------------------------------------
Rv0891c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2962|M.marinum_M DGVRYVDLGSITDPAVAPITMARALGLPNQPGRSAMDTLLHHLGDRQMLL
Mvan_5928|M.vanbaalenii_PYR-1 GGVWYVDLAPITDPALVAITVARALGLPDQPGRSTVDTIVRFIADRRMLV
MLBr_01753|M.leprae_Br4923 GELSYFDLAPDTDHDIFPITVL--------------DNLRRCIGDRRMLM
MUL_2743|M.ulcerans_Agy99 DGVWLFELAAVSDPAAVPDAVAAVLGITQQAGKTVTQSVATALERRVRLL
Mb0915c|M.bovis_AF2122/97 --------------------------------------------------
Rv0891c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2962|M.marinum_M LVDNCEHLLDASAPRLGAMLRDCPGLRLLVTSREPIKVAGEVTWRVPPLA
Mvan_5928|M.vanbaalenii_PYR-1 VLDNCEHLLDACATLIDALLGACPALAMLATSREPIAVAGEQTWRVPPLA
MLBr_01753|M.leprae_Br4923 VLDNCEYLLDVCANVMTTLLGACPSLTILATSREPIGVAGEVIWRVSMLS
MUL_2743|M.ulcerans_Agy99 VFDNCEHVRDAAADLIEAILAGSTTVRILATSRERLEVPDEQLWSVPSLD
Mb0915c|M.bovis_AF2122/97 --------------------------------------------------
Rv0891c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2962|M.marinum_M VG-----DAIALFTDRARLAQPDFALTDDNAGTVS-QICRRLDTQPLGIE
Mvan_5928|M.vanbaalenii_PYR-1 LDD----DAIELFTDRARRARPDFIISADDAAAVS-EICHRLDGMPLAIE
MLBr_01753|M.leprae_Br4923 PAD----EAVELFTERAALVQPGFSVTDGNRQIVT-EICQRLDGMPLAIE
MUL_2743|M.ulcerans_Agy99 VGGGVVSAAGTLFVERAQSVAPGFAPTDAQDAAAIGEICRRLDGIPLAIE
Mb0915c|M.bovis_AF2122/97 --------------------------------------------------
Rv0891c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2962|M.marinum_M LAAARVRTLSLAEISAGLDDKIRLLTGGARTAVPRQQTLRASLEWSHGLL
Mvan_5928|M.vanbaalenii_PYR-1 LAAARVRALSLTEIVDGLHDRFRLLTGGSRTAVRRQQTLRASVDWSHGLL
MLBr_01753|M.leprae_Br4923 LAAARIRTLSLTEIADGLDDRFRLLTGGARTAVRRQQTLRASMDWSYALL
MUL_2743|M.ulcerans_Agy99 LAASRMASMTPIEVRDRLDHRFRLLVGSRR-GLGRHQTLRHAVAWSYDHL
Mb0915c|M.bovis_AF2122/97 --------------------------------------------------
Rv0891c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2962|M.marinum_M TDTERVLFRRLGVFVGGFDLQAAQAVA-AFGDVHPRDVLGDLSQLVDKSL
Mvan_5928|M.vanbaalenii_PYR-1 TDPERVLFRRLAVFAGGFDLDGAQAIT-VDGEVHRYEVVDLLTLLVDKSL
MLBr_01753|M.leprae_Br4923 TESERALFRRLSAISGTFDLKVAYAVG-HDDLEEPDQVFDRLTMLIDKSL
MUL_2743|M.ulcerans_Agy99 SDAEKVLLERCSVFAGGFDLQSACAVAGSADTHDDYEVLDLLDALVGKSL
Mb0915c|M.bovis_AF2122/97 --------------------------------------------------
Rv0891c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2962|M.marinum_M VVADSSNGRTRYRRFEGVGQLALEKLREAGEADIARARHCDHYTAVVAPL
Mvan_5928|M.vanbaalenii_PYR-1 LIAENTAGRTRYRLLETVRQYAQEKLGESGEADTLRARHRDHYTARAAEL
MLBr_01753|M.leprae_Br4923 VIVEGRQGGSRYRLLETVRQYAMKKLEESNEVDLVLARHRDHYMALGALL
MUL_2743|M.ulcerans_Agy99 LIVDRLSGRSRFSMLETIREFAEEQLVTRGQALAARTAHARHFAQRLPDV
Mb0915c|M.bovis_AF2122/97 --------------------------------------------------
Rv0891c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2962|M.marinum_M DLPARAD-YDFLLARVEGELENLRAASAWLLESSDGESALMLASRLQPLW
Mvan_5928|M.vanbaalenii_PYR-1 DAPSVAG-HERRLNQTDIEMDNLRAAFAWSRENANTDHSLLLASSLHPLW
MLBr_01753|M.leprae_Br4923 DTPGDID-HEQLVEQVETELDNLRSAFAWSRETGDIAGALQLASSLQPIW
MUL_2743|M.ulcerans_Agy99 AAVWDSPRQPEAYTWLTAELANLRLAFRWTADNNDLDDAASIATWVGFLG
Mb0915c|M.bovis_AF2122/97 --------------------------------------------------
Rv0891c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2962|M.marinum_M LVRGRISEGRSWFDAALAG--ASVLEVSPTVRARALADAAVLTMFVDVAT
Mvan_5928|M.vanbaalenii_PYR-1 RARGRLQEGQAWFDAALTDYEARPGEADPAVYARALADRAFMDGHVGITD
MLBr_01753|M.leprae_Br4923 FGRGHMYEGLAWFDSIFEHKNIEHLVAPKEVLARAVANKVMLHAILASSP
MUL_2743|M.ulcerans_Agy99 FLVN-RFEPLTWVEEAIERAVDHPKLAFLHVLASQCYTTG----------
Mb0915c|M.bovis_AF2122/97 --------------------------------------------------
Rv0891c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2962|M.marinum_M S-----LESAAAALAIARELDDPASLVRALTACGLTASFSHHTEAVGQYF
Mvan_5928|M.vanbaalenii_PYR-1 R-----LDQAQKALAMARDIDDPALLVRALTACGGLAAYN--ADVARPLL
MLBr_01753|M.leprae_Br4923 PDGSDLVTQAQQALTMAREIGDSAVLARALTACGFSSGYD--TEVARPYF
MUL_2743|M.ulcerans_Agy99 --------RVQEAIRYADEAARLLATDRYEVPFG-IEGWPSGACTSSGHP
Mb0915c|M.bovis_AF2122/97 --------------------------------------------------
Rv0891c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2962|M.marinum_M AEAASLAEELDDQWGLSQILSWQSNAAVVAG-DAIAARRIGTEGRDLADA
Mvan_5928|M.vanbaalenii_PYR-1 AEAVDLARSMGDKWMLAETLAWQAYAALMGGGDPVAARTAGEEARELADE
MLBr_01753|M.leprae_Br4923 AEAVELARTQGDKWTLSQIRLWGVVGFCVSG-DPVALRAAAEAADDLAQE
MUL_2743|M.ulcerans_Agy99 EQSVELCRTQLALGHDTHTLTLG---------------------------
Mb0915c|M.bovis_AF2122/97 --------------------------------------------------
Rv0891c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2962|M.marinum_M IGDRFNSWLCRLSLGYAQLWQGDLTGATTQFGALSEAENLASLSSKG---
Mvan_5928|M.vanbaalenii_PYR-1 MGDGFVSRICGWLLGIAHHFQGDLDAALALADGVVSESDVAHDTLNGCCG
MLBr_01753|M.leprae_Br4923 IGDRFVSLQCRLLLSIAQLWQGDMDGAIVRSGEVVAGAEAAHDTVTRTFG
MUL_2743|M.ulcerans_Agy99 ------------CLVLALTIKGQCDEAEQLADALIESAEATRN-------
Mb0915c|M.bovis_AF2122/97 --------------------------------------------------
Rv0891c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2962|M.marinum_M ---LGDALAYRGDVDAARTAAEAALERAAESSEYTLGLGYSTVALAALAG
Mvan_5928|M.vanbaalenii_PYR-1 ELVLAHSLAQRGDTDAARAAAQVSLNVAVEVSPVHAGLAHAALAVANLAA
MLBr_01753|M.leprae_Br4923 LYVQTRALVHR-DVSAALVTAGLVVEAAAELSGVYQGIGYAAMVFAALAM
MUL_2743|M.ulcerans_Agy99 ---------------------------------------PAALCYALLAY
Mb0915c|M.bovis_AF2122/97 --------------------------------------------------
Rv0891c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2962|M.marinum_M GDVETARNASDLAWHKLSVQPYAAMFWHSFRAEIALACGNVAGAKRCADE
Mvan_5928|M.vanbaalenii_PYR-1 GDVTAAEAASDSATRSFGPSEVAGIQDPNVAAQIACTRGDLDTARSLVDG
MLBr_01753|M.leprae_Br4923 GDVAAAVEASEACRPHLGADHGLVAIHLELMAAVALARGDVIVARRLADN
MUL_2743|M.ulcerans_Agy99 G----------------------------FTFRDTNPASALAAMRRGLRI
Mb0915c|M.bovis_AF2122/97 --------------------------------------------------
Rv0891c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2962|M.marinum_M AVSVTTGWHRALALTTRARVAMAEGEPEQAERAAYEALTCAADVGARTCL
Mvan_5928|M.vanbaalenii_PYR-1 AVSITRGVHRASALTTRARIAIAQGDPEQAERNAHDALSLAAGVGARLEV
MLBr_01753|M.leprae_Br4923 SVSATTGWHQMAALTTRARIAMAQGEPELARADIHAALACGADIQASLGI
MUL_2743|M.ulcerans_Agy99 AQDTGNRNSETHLAAVLCRVEAKYGDPLSALDHFTLAIHNHHEAGNTTLI
Mb0915c|M.bovis_AF2122/97 --------------------------------------------------
Rv0891c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2962|M.marinum_M PDILECLGALAADQGRDREAARVYGAAEGIRQRIGAMRFKIYDAGYQKSV
Mvan_5928|M.vanbaalenii_PYR-1 PDTLECLARVVGDGGSHHEAARLCGAAEAIRGRTGAVRFRIYDADHETTV
MLBr_01753|M.leprae_Br4923 SDSMELLAELISQGDNHRQAGRLFGAASAQREKTGEVRFKVWDAGYESAV
MUL_2743|M.ulcerans_Agy99 STPLAVLAAFFDRLGRYEAAATIAGFAFHPITEASFP-------ELRTTI
Mb0915c|M.bovis_AF2122/97 --------------------------------------------------
Rv0891c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2962|M.marinum_M AALHATMSTDEFDTAWAHGAAFSAEEAIDYLQHRRGERKRATSGWAALTR
Mvan_5928|M.vanbaalenii_PYR-1 TTLRDALGDKAFEAAWTEGSATSITEAIAYAQRGRGERKRPSSGWASLTP
MLBr_01753|M.leprae_Br4923 AVLRGAMGCKDFDSAWAEGAAMPIDDAITYAQRGRGNRKRPTTGWESLTP
MUL_2743|M.ulcerans_Agy99 SHLRDALGDHAYESFSQSGAAMTTAAMATYAYHQIDHARTEFQAR-----
Mb0915c|M.bovis_AF2122/97 --------------------------------------------------
Rv0891c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2962|M.marinum_M AELNVVRLVGQGLSNKDIAQRLFLSPRTVQTHLTHVYTKLGFNSRVQLAQ
Mvan_5928|M.vanbaalenii_PYR-1 TELDVVGLVSEGLSNKDIAARLFVSPRTVQTHLTHVYTKLCLASRVQLAQ
MLBr_01753|M.leprae_Br4923 AEHNVIRLVSEGLDTKDIAARLFVSVRTVHTHLTRIYSKLGLTSRVQLVQ
MUL_2743|M.ulcerans_Agy99 --------------------------------------------------
Mb0915c|M.bovis_AF2122/97 ------
Rv0891c|M.tuberculosis_H37Rv ------
MSMEG_0545|M.smegmatis_MC2_155 ------
MMAR_2962|M.marinum_M QAAQHS
Mvan_5928|M.vanbaalenii_PYR-1 EAARHT
MLBr_01753|M.leprae_Br4923 EAARHN
MUL_2743|M.ulcerans_Agy99 ------