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VNFSVLPPEINSGRMFFGAGSGPMLAAAAAWDGLAAELGLAAESFGLVTSGLAGGSGQAWQGAAAAAMVV AAAPYAGWLAAAAARAGGAAVQAKAVAGAFEAARAAMVDPVVVAANRSAFVQLVLSNVFGQNAPAIAAAE ATYEQMWAADVAAMVGYHGGASAAAAALAPWQQAVPGLSGLLGGAANAPAAAAQGAAQGLAELTLNLGVG NIGSLNLGSGNIGGTNVGSGNVGGTNLGSGNYGSLNWGSGNTGTGNAGSGNTGDYNPGSGNFGSGNFGSG NIGSLNVGSGNFGTLNLANGNNGDVNFGGGNTGDFNFGGGNNGTLNFGFGNTGSGNFGFGNTGNNNIGIG LTGDGQIGIGGLNSGTGNIGFGNSGNNNIGFFNSGDGNIGFFNSGDGNTGFGNAGNINTGFWNAGNLNTG FGSAGNGNVGIFDGGNSNSGSFNVGFQNTGFGNSGAGNTGFFNAGDSNTGFANAGNVNTGFFNGGDINTG GFNGGNVNTGFGSALTQAGANSGFGNLGTGNSGWGNSDPSGTGNSGFFNTGNGNSGFSNAGPAMLPGFNS GFANIGSFNAGIANSGNNLAGISNSGDDSSGAVNSGSQNSGAFNAGVGLSGFFR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2356c | PPE40 | - | 100% (615) | PPE FAMILY PROTEIN |
| M. tuberculosis H37Rv | Rv3159c | PPE53 | 0.0 | 62.64% (613) | PPE family protein |
| M. tuberculosis H37Rv | Rv1135c | PPE16 | 0.0 | 59.27% (626) | PPE family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2377c | PPE40 | 0.0 | 99.84% (615) | PPE family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 2e-35 | 29.15% (669) | triple helix repeat-containing collagen |
| M. leprae Br4923 | MLBr_01182 | - | 6e-29 | 41.57% (166) | PPE-family protein |
| M. abscessus ATCC 19977 | MAB_0809c | - | 8e-24 | 37.20% (164) | PPE family protein |
| M. marinum M | MMAR_3666 | - | 0.0 | 72.27% (642) | PPE family protein |
| M. avium 104 | MAV_4704 | - | 2e-51 | 54.55% (198) | PPE family protein |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 6e-27 | 26.54% (697) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3113 | - | 7e-24 | 38.38% (198) | PUTATIVE PPE protein |
| M. ulcerans Agy99 | MUL_0964 | - | 0.0 | 60.79% (630) | PPE family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 6e-40 | 31.90% (605) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2356c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2377c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3666|M.marinum_M --------------------------------------------------
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_0809c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
Rv2356c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2377c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3666|M.marinum_M --------------------------------------------------
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_0809c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
Rv2356c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2377c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3666|M.marinum_M --------------------------------------------------
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_0809c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
Rv2356c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2377c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3666|M.marinum_M --------------------------------------------------
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_0809c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
Rv2356c|M.tuberculosis_H37Rv -----------------------------------MVN--FSVLPPEINS
Mb2377c|M.bovis_AF2122/97 -----------------------------------MVN--FSVLPPEINS
MMAR_3666|M.marinum_M ------------------------------------MN--FAVLPPEINS
MUL_0964|M.ulcerans_Agy99 ------------------------------------MN--FMMLPPEVNS
MAV_4704|M.avium_104 -----------------------------------MTNPHFAWLPPEVNS
MLBr_01182|M.leprae_Br4923 -----------------------------------MFD--FAALSPETNS
MAB_0809c|M.abscessus_ATCC_199 ----------------------------------MLAAPVWMASPPEVHS
TH_3113|M.thermoresistible__bu -----------------------------------------MALPPEVHS
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
: .
Rv2356c|M.tuberculosis_H37Rv GRMFFGAGSGPMLAAAAAWDGLAAELGLAAESFGLVTSGLAGGSGQAWQG
Mb2377c|M.bovis_AF2122/97 GRMFFGAGSGPMLAAAAAWDGLAAELGLAAESFGLVTSGLAGGSGQAWQG
MMAR_3666|M.marinum_M VRMFSGAGSEPMLAAAAAWDGLSAELGEAAESFASVTSGLAG-AGQAWQG
MUL_0964|M.ulcerans_Agy99 ALMFTGAGSAPTLAAATAWDGLVAELGEAAEAFSSVTSGLAS---GSWQG
MAV_4704|M.avium_104 ALIYSGPGPGPLLAAAAAWDGLAEELASSAQSFSSVTSDLAS---GSWQG
MLBr_01182|M.leprae_Br4923 TRMYLGPGSSPILTAAAAWVVLAKELTAAAQGLQSAVEALLT----TFEG
MAB_0809c|M.abscessus_ATCC_199 ALLSSGPGPGPLLAAAAEWSSLGAHYSATAQELRAILAATHA---SAWHG
TH_3113|M.thermoresistible__bu TLLRTGPGPGALSAAADAWRMLSDEYRAAAVELAAVVSQTCA---TAWEG
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
* .. : .
Rv2356c|M.tuberculosis_H37Rv AAAAAMVVAAAPYAGWLAAAAARAGGAAVQAKAVAG-----AFEAARAAM
Mb2377c|M.bovis_AF2122/97 AAAAAMVVAAAPYAGWLAAAAARAGGAAVQAKAVAG-----AFEAARAAM
MMAR_3666|M.marinum_M AAASAMVAAAGPYASWLGAAAARAAGASASAKVVAS-----AFEAARAAM
MUL_0964|M.ulcerans_Agy99 PAAAAMAAAAAPYAGWLSAAATRALGAATQAKAAAA-----VFESAQAAT
MAV_4704|M.avium_104 ASSAAMMTVANQYVSWLSAAAAQAEEVSHQASAIAT-----AFEVALAAT
MLBr_01182|M.leprae_Br4923 ESAAALAERVTPYEKWLTQNAASAELTATQLTVAAN-----AYETAFTMT
MAB_0809c|M.abscessus_ATCC_199 PSAETYVAAHTPYLEWLNQGALESNARAVQHGAAAG-----AYSTALAVM
TH_3113|M.thermoresistible__bu VGADAYAAAHGPYLFWLTDTAAAAAAAGAQLEAAAA-----AHASALAAM
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
. . . . .
Rv2356c|M.tuberculosis_H37Rv VDPVVVAANRSAFVQLVLSNVFGQNAPAIAAAEATY------------EQ
Mb2377c|M.bovis_AF2122/97 VDPVVVAANRSAFVQLVLSNVFGQNAPAIAAAEATY------------EQ
MMAR_3666|M.marinum_M VHPLAVAANRNGFVQLVMSNLFGQNAPAIAAAEGVY------------EE
MUL_0964|M.ulcerans_Agy99 VHPELVLANRNQLVSLVLSNLFGQNAPAIAATESTY------------EE
MAV_4704|M.avium_104 VQPAVVAANRALVQALAATNWLGQNTPAIADIEAAY------------EQ
MLBr_01182|M.leprae_Br4923 VPPLMVFVNRAQACLLIMSNIFGQNSTAIAEKEAEY------------TE
MAB_0809c|M.abscessus_ATCC_199 PTLAELAANHATHAALVATNFFGINTIPILATEADY------------VR
TH_3113|M.thermoresistible__bu PTMAELTANRTTHAALVATNFFGVNTIPIAVNEADY------------AR
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
. :. * . .
Rv2356c|M.tuberculosis_H37Rv MWAADVAAMVGYHGGASAAAAALAPWQ---------------------QA
Mb2377c|M.bovis_AF2122/97 MWAADVAAMVGYHGGAS-AAAALAPWQ---------------------QA
MMAR_3666|M.marinum_M MWAADVAAMAGYHGGASAAAAQLSSWQGMVSGVL--------------SG
MUL_0964|M.ulcerans_Agy99 LWAQDVAATVGYHGGASAVAAQLAPWQ---------------------QA
MAV_4704|M.avium_104 MWASDVAAMFGYHADASAAVAKLPPWN-----------------------
MLBr_01182|M.leprae_Br4923 MWIQDAAAMTSYQASVLEAVGATKAFT-----------------------
MAB_0809c|M.abscessus_ATCC_199 MWVQAATTMATYQTASEVALASAPPSTP----------------------
TH_3113|M.thermoresistible__bu MWIQAATTMATYEAVASAAVSATPRTVA----------------------
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----------------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----------------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
: .
Rv2356c|M.tuberculosis_H37Rv VPGLSGLLGGAANAP---------------------AAAAQGAAQGLAEL
Mb2377c|M.bovis_AF2122/97 VPGLSGLLGGAANAP---------------------AAAAQGAAQGLAEL
MMAR_3666|M.marinum_M VPGVSGLVGGAAPAAAAVTTPLASAQLGVQALGSSAAAAPAAVSQELSDL
MUL_0964|M.ulcerans_Agy99 IQALPGRVAAMATTG------------------PAASAAAALASGPAAAL
MAV_4704|M.avium_104 --------------------------------------------EVLQN-
MLBr_01182|M.leprae_Br4923 -------------------------------------------APPLGVN
MAB_0809c|M.abscessus_ATCC_199 ------------------------------------------PPSILHDH
TH_3113|M.thermoresistible__bu ------------------------------------------PPPILGAG
Mflv_5091|M.gilvum_PYR-GCK AVGAAGAAG------TVGTAGATGGTG---------------TGANGGAG
Mvan_1264|M.vanbaalenii_PYR-1 AIGTAGVAG------AAGTAGATGGTG---------------VGGNGGAG
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
Rv2356c|M.tuberculosis_H37Rv TLN-------LGVGNIGSLNLGSGNIGGTNVGSGNVGGTNLGSGNYGSLN
Mb2377c|M.bovis_AF2122/97 TLN-------LGVGNIGSLNLGSGNIGGTNVGSGNVGGTNLGSGNYGSLN
MMAR_3666|M.marinum_M IFN-------LGIGNVGTFNLGSGNLGNTNLGSGNVGNQNVGSGNYGSGN
MUL_0964|M.ulcerans_Agy99 DIGNNGSGNFLSIGNIGNNNLGSGNTGSANLGGGNIGNGNLGSGNTGNVN
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 EVG-----------------------------------------------
MAB_0809c|M.abscessus_ATCC_199 DHG-----------------------------HDDHDHEHGHDDDHGHGD
TH_3113|M.thermoresistible__bu TG---------------------------------ESATAAITGAHVTAE
Mflv_5091|M.gilvum_PYR-GCK GVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGGQ-
Mvan_1264|M.vanbaalenii_PYR-1 QAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGGQ-
MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
Rv2356c|M.tuberculosis_H37Rv WGSGNTGTGNAGSGNTGDYNPGSGNFGSGNFGSGN-IGSLNVGSGN-FGT
Mb2377c|M.bovis_AF2122/97 WGSGNTGTGNAGSGNTGDYNPGSGNFGSGNFGSGN-IGSLNVGSGN-FGT
MMAR_3666|M.marinum_M WGGGNTGTGNTGSGNAGDYNFGSGNFGSGNLGSGN-IGSLNLGSGN-FGT
MUL_0964|M.ulcerans_Agy99 LGNGNNGFFNFGNGNLGDTNFGSGNSGNLNLGSGNRFGSGNIGFGNRFGD
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_0809c|M.abscessus_ATCC_199 LDPTDPEWWVHVAGEMVEHFELLLNN------------------------
TH_3113|M.thermoresistible__bu LRAAESRTLLDEINELIDRLFAPLFPPGFADALPD---------------
Mflv_5091|M.gilvum_PYR-GCK -GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG-----------
Mvan_1264|M.vanbaalenii_PYR-1 -GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG-----------
MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
Rv2356c|M.tuberculosis_H37Rv LNLANGNNGDVNFGGGNTGDFNFGGGNNGTLNFGFGNTGSGNFGFGNTGN
Mb2377c|M.bovis_AF2122/97 LNLANGNNGDVNFGGGNTGDFNFGGGNNGTLNFGFGNTGSGNFGFGNTGN
MMAR_3666|M.marinum_M LNLFGGNNGDLGLGSGNTGDVNVGSGNNGGGNIGFGNLGDNNIGFGNKGS
MUL_0964|M.ulcerans_Agy99 GNFGSGNAGSYNFGTGNNGSFNIGSGNNGDSNIGFGNLGTNNLGFGNNGS
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_0809c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3113|M.thermoresistible__bu ---------------------GLLGTLLAPLLPGATGDGPPMATIMSFLL
Mflv_5091|M.gilvum_PYR-GCK --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK
Mvan_1264|M.vanbaalenii_PYR-1 --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK
MSMEG_0868|M.smegmatis_MC2_155 KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV
Rv2356c|M.tuberculosis_H37Rv NNIGIGLTGDGQIG------------------------------------
Mb2377c|M.bovis_AF2122/97 NNIGIGLTGDGQIG------------------------------------
MMAR_3666|M.marinum_M GNIGFGLTGDGQFG------------------------------------
MUL_0964|M.ulcerans_Agy99 NNIGFGLSGSNQIG------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 ------------LA------------------------------------
MAB_0809c|M.abscessus_ATCC_199 -LLTDPAALLTNLP------------------------------------
TH_3113|M.thermoresistible__bu MGLSNPAYLFPVLV------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGRGGLFG---------------KGGNAGNGAD-----------
Mvan_1264|M.vanbaalenii_PYR-1 GGNGGNGGRGSLFG---------------RGGNAGNGGN-----------
MSMEG_0868|M.smegmatis_MC2_155 GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP
Rv2356c|M.tuberculosis_H37Rv ------------IGGLNSGTGNIGFGNSGNNNIGF---------------
Mb2377c|M.bovis_AF2122/97 ------------IGGLNSGTGNIGFGNSGNNNIGF---------------
MMAR_3666|M.marinum_M ------------IGGFNSGTGNIGLFNSGNNNIGF---------------
MUL_0964|M.ulcerans_Agy99 ------------IGGLNAGIGNMGFGNAGDNNVGF---------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 ------------QEVVEEVVEEVVEEVVEAEQAIS---------------
MAB_0809c|M.abscessus_ATCC_199 ------------MVLADVAFHAAQLASTIGQFAPA---------------
TH_3113|M.thermoresistible__bu ------------YLLFTGVVHTTVAVSGMLAQLVP---------------
Mflv_5091|M.gilvum_PYR-GCK -----------GGTGGAGGAGGTGG-TGGAGGTGG---------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------GGTGGNGGNGGTGG-TGGNGGTGG---------------
MSMEG_0868|M.smegmatis_MC2_155 AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ
Rv2356c|M.tuberculosis_H37Rv -------FNSGDGNIGFFNSGDGNTGFGNAGNINTGFWNAGNLNTGFGSA
Mb2377c|M.bovis_AF2122/97 -------FNSGDGNIGFFNSGDGNTGFGNAGNINTGFWNAGNLNTGFGSA
MMAR_3666|M.marinum_M -------FNSGDNNFGWCNSGSGNTGFGNAGNFNTGFWNAGSSNTGFGSA
MUL_0964|M.ulcerans_Agy99 -------FNSGSNNIGFFNSGDGNFGFAHAGSTNTGFWNSGGTNTGFGNG
MAV_4704|M.avium_104 ------------------------LGFSNASTAVTRPAGSGAVARGYTSR
MLBr_01182|M.leprae_Br4923 -------QAALDQAVNEGMEATVVPQVDQQVNVDVATPQTAVPDSSSAAA
MAB_0809c|M.abscessus_ATCC_199 -------LIQPALALAIANLG-WAAGFAGLAGIQPSPEILAVEPGSVEDA
TH_3113|M.thermoresistible__bu -------LMPALLPVAVAALGGLAGVWAGLSGLAGLAGLTAVP---AADG
Mflv_5091|M.gilvum_PYR-GCK --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
Mvan_1264|M.vanbaalenii_PYR-1 --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
MSMEG_0868|M.smegmatis_MC2_155 TDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRG
.
Rv2356c|M.tuberculosis_H37Rv GNGNVGIFDGGNSNSGSFNVGFQNTGFGNSG-------------AGNTGF
Mb2377c|M.bovis_AF2122/97 GNGNVGIFDGGNSNSGSFNVGFQNTGFGNSG-------------AGNTGF
MMAR_3666|M.marinum_M GDGNFGLFNAGNHNSGSFNVGTESTGFGNSG-------------AGNTGF
MUL_0964|M.ulcerans_Agy99 GSLNFGFGNGGVENMGHGNAGSFNMGFGNGG-------------GGNTGF
MAV_4704|M.avium_104 ----------------------------------------------IAGF
MLBr_01182|M.leprae_Br4923 PQLWGGFAQHLSPINDTLSMINNHAGMANAG-------------LSLVNG
MAB_0809c|M.abscessus_ATCC_199 PMAASAGTALAPSPPASAAAPAAPASAPAPT-------------ASGTAP
TH_3113|M.thermoresistible__bu GASAAPVPAGGPSLPSGSSAPPAPTGSAAPT-------------TGTAPG
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGG
Rv2356c|M.tuberculosis_H37Rv FN------------------------------------------------
Mb2377c|M.bovis_AF2122/97 FN------------------------------------------------
MMAR_3666|M.marinum_M MN------------------------------------------------
MUL_0964|M.ulcerans_Agy99 YN------------------------------------------------
MAV_4704|M.avium_104 LA------------------------------------------------
MLBr_01182|M.leprae_Br4923 MG------------------------------------------------
MAB_0809c|M.abscessus_ATCC_199 AP------------------------------------------------
TH_3113|M.thermoresistible__bu GA------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AG-----------DGTGGTGGTGG----TGGQGGQGGQGG----------
Mvan_1264|M.vanbaalenii_PYR-1 AG-----------DGLGGTGGTGG----TGGFGGQGGQGG----------
MSMEG_0868|M.smegmatis_MC2_155 AGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIG
Rv2356c|M.tuberculosis_H37Rv --------AGDSNTGFANAGNVNTGFF-----------------------
Mb2377c|M.bovis_AF2122/97 --------AGDSNTGFANAGNVNTGFF-----------------------
MMAR_3666|M.marinum_M --------AGNSNTGAFNGGNVNTGFF-----------------------
MUL_0964|M.ulcerans_Agy99 --------SGTYNTGFSNAAETNTGWE-----------------------
MAV_4704|M.avium_104 --------PRAPQ-------------------------------------
MLBr_01182|M.leprae_Br4923 --------SAMKSLAPTTTKAAESAFK-----------------------
MAB_0809c|M.abscessus_ATCC_199 --------PSPPPVGD-----PGFSFP-----------------------
TH_3113|M.thermoresistible__bu --------GSPPPAGHSVPPAPHSAPP-----------------------
Mflv_5091|M.gilvum_PYR-GCK -------TGGTGGQGG-LGGGGGTG-----------------------GQ
Mvan_1264|M.vanbaalenii_PYR-1 -------TGGTGGQGG-LGGVGGTG-----------------------GT
MSMEG_0868|M.smegmatis_MC2_155 SNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGH
Rv2356c|M.tuberculosis_H37Rv ----------------------------------NGGDINTGGFNGGNVN
Mb2377c|M.bovis_AF2122/97 ----------------------------------NGGDINTGGFNGGNVN
MMAR_3666|M.marinum_M ----------------------------------NGGNTNTGAFNGGDLN
MUL_0964|M.ulcerans_Agy99 ----------------------------------NSGNVNTGGYNSGGLN
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 ----------------------------------AMGSAVQSTGRGLLGS
MAB_0809c|M.abscessus_ATCC_199 ----------------------------------YAVGGGPRLGTGLALA
TH_3113|M.thermoresistible__bu ----------------------------------VGTSGPPYLIAAQPAP
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGS
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGV
MSMEG_0868|M.smegmatis_MC2_155 GGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGD
Rv2356c|M.tuberculosis_H37Rv TGFGSALTQAGANSGFGNLGTGNS----------------------GWGN
Mb2377c|M.bovis_AF2122/97 TGFGSALTQAGANSGFGNLGTGNS----------------------GWGN
MMAR_3666|M.marinum_M TAIGSSVSQSGLNSGFGNLGSGNS----------------------GFYN
MUL_0964|M.ulcerans_Agy99 TGIGSPDTQAGPNSGFGHSGSGNS----------------------GFFN
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 SSGGHVTAQLGRAASIGSLRVPQT----------------------WTTA
MAB_0809c|M.abscessus_ATCC_199 AQVRRGTSAAARSSAREQAAAAET----------------------AAAR
TH_3113|M.thermoresistible__bu GVARRSAGARRAASIVEPAGSAAA----------------------AAAA
Mflv_5091|M.gilvum_PYR-GCK GGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGKA
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGTA
MSMEG_0868|M.smegmatis_MC2_155 GVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTL
Rv2356c|M.tuberculosis_H37Rv SDP--SGTGNSGFFNTGNGNSGFSNAGPAMLPGFNSGFANIGSFNAGIAN
Mb2377c|M.bovis_AF2122/97 SDP--SGTGNSGFFNTGNGNSGFSNAGPAMLPGFNSGFANIGSFNAGIAN
MMAR_3666|M.marinum_M SDP--NGSANSGFFNTGIGNSGVSNAGPALVPGYNSGFGNIGTNNAGFVN
MUL_0964|M.ulcerans_Agy99 SGDGNSGFENSNTCVSANGHSGVRNSG----DATNVGFSNSGSNNTGIFN
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 SQPVTAATRALSPARVAVATE---------------------SESAPLLG
MAB_0809c|M.abscessus_ATCC_199 QARR--RRDKGKQQGRGIEYMDMNATARCEEPAPDTTASHRGAGTMGFAG
TH_3113|M.thermoresistible__bu RESAPIRRRRGQKDGLHGHRHEHQQPASMSAATAPSAAGIR---VLGGAG
Mflv_5091|M.gilvum_PYR-GCK GATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGATG
Mvan_1264|M.vanbaalenii_PYR-1 GVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGSAG
MSMEG_0868|M.smegmatis_MC2_155 GGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGG
Rv2356c|M.tuberculosis_H37Rv SGNNLAGISNSG---------------DDSSGAVNSGSQNSGAFNAGVGL
Mb2377c|M.bovis_AF2122/97 SGNNLAGISNSG---------------DDSSGAVNSGSQNSGAFNAGVGL
MMAR_3666|M.marinum_M SGNRLAGISNSG---------------DDSSGFLNSGDQNSGGFNSGTGL
MUL_0964|M.ulcerans_Agy99 TGTFNTGIANSG---------------SDSSGLLISGTNSSGALNSGDDQ
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 GGLPMAPMVPGG---------------GSGTGGVNTALRLQPRAFVMPRN
MAB_0809c|M.abscessus_ATCC_199 TVIKTGATASGL---------------AMLSRDDDLFEGVRAPMVPNTWD
TH_3113|M.thermoresistible__bu RISRTRGSVPHA---------------EITPGDP------TEPSSPTDRA
Mflv_5091|M.gilvum_PYR-GCK AAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA
Mvan_1264|M.vanbaalenii_PYR-1 SAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA
MSMEG_0868|M.smegmatis_MC2_155 AATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWV
Rv2356c|M.tuberculosis_H37Rv SGFFR---------------------------------------------
Mb2377c|M.bovis_AF2122/97 SGFFR---------------------------------------------
MMAR_3666|M.marinum_M SGFFR---------------------------------------------
MUL_0964|M.ulcerans_Agy99 SGFNN---------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 PAAG----------------------------------------------
MAB_0809c|M.abscessus_ATCC_199 PEHGRQD-------------------------------------------
TH_3113|M.thermoresistible__bu HRPAEPN-------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG-------
Mvan_1264|M.vanbaalenii_PYR-1 GATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG-------
MSMEG_0868|M.smegmatis_MC2_155 QAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKS
Rv2356c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2377c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3666|M.marinum_M --------------------------------------------------
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_0809c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG-
Mvan_1264|M.vanbaalenii_PYR-1 ----AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG-
MSMEG_0868|M.smegmatis_MC2_155 GGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGN
Rv2356c|M.tuberculosis_H37Rv ---------------------------
Mb2377c|M.bovis_AF2122/97 ---------------------------
MMAR_3666|M.marinum_M ---------------------------
MUL_0964|M.ulcerans_Agy99 ---------------------------
MAV_4704|M.avium_104 ---------------------------
MLBr_01182|M.leprae_Br4923 ---------------------------
MAB_0809c|M.abscessus_ATCC_199 ---------------------------
TH_3113|M.thermoresistible__bu ---------------------------
Mflv_5091|M.gilvum_PYR-GCK -GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 -GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGGNGGADGTPGTAGTTGANNP