For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3113 | - | - | 100% (519) | PPE protein |
| M. thermoresistible (build 8) | TH_3569 | - | 1e-64 | 43.63% (353) | PUTATIVE PPE protein |
| M. thermoresistible (build 8) | TH_4447 | - | 5e-32 | 29.88% (415) | PUTATIVE PPE protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0262c | PPE2 | 9e-72 | 37.23% (564) | PPE family protein |
| M. gilvum PYR-GCK | Mflv_0325 | - | 1e-72 | 36.91% (531) | PPE protein |
| M. tuberculosis H37Rv | Rv0256c | PPE2 | 9e-72 | 37.23% (564) | PPE family protein |
| M. leprae Br4923 | MLBr_01828 | PPE | 2e-63 | 34.48% (551) | PPE-family protein |
| M. abscessus ATCC 19977 | MAB_4783 | - | 1e-72 | 39.15% (493) | PPE family protein |
| M. marinum M | MMAR_1418 | - | 4e-71 | 38.68% (517) | PPE family protein |
| M. avium 104 | MAV_1329 | - | 9e-77 | 39.32% (529) | PPE family protein |
| M. smegmatis MC2 155 | MSMEG_0619 | - | 3e-70 | 40.00% (505) | PPE family protein |
| M. ulcerans Agy99 | MUL_1202 | - | 3e-69 | 41.09% (460) | PPE family protein |
| M. vanbaalenii PYR-1 | Mvan_0415 | - | 1e-79 | 39.96% (528) | PPE protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1418|M.marinum_M ----------MTAPIWMASPPEVHSALLSSGPGPGPLLSAAAAWSQLSNE
MUL_1202|M.ulcerans_Agy99 --------------MWFTSPPEVHSALLSSGPGPASLLSGAAAWAGLSTE
Mflv_0325|M.gilvum_PYR-GCK MTSPVASLAPVTSPVWMALPPEVHSTMLSSGPGPGSLLAAGVAWQSLSAE
Mvan_0415|M.vanbaalenii_PYR-1 ----------MSSPVWMALPPEVHSALLSSGPGPGSMLAAAATWQSLSAE
MSMEG_0619|M.smegmatis_MC2_155 ----------MTAPIWMALPPEVHSSLLSSGPGPGSLLAAAGAWQSLSAE
MAB_4783|M.abscessus_ATCC_1997 ----------MTAPVWMAAPPEVHSALLSSGPGPGSLFAAADAWRSLSTE
Mb0262c|M.bovis_AF2122/97 ----------MTAPIWMASPPEVHSALLSSGPGPGPLLVSAEGWHSLSIA
Rv0256c|M.tuberculosis_H37Rv ----------MTAPIWMASPPEVHSALLSSGPGPGPLLVSAEGWHSLSIA
MLBr_01828|M.leprae_Br4923 ----------MSAPIWMASPPEVHSALLSRGPGSGPLLVAAEAWRSLSSV
MAV_1329|M.avium_104 -------MRSMTAPIWMASPPEVHSSLLSAGPGPGPLLAAAAAWSSLSVQ
TH_3113|M.thermoresistible__bu ----------------MALPPEVHSTLLRTGPGPGALSAAADAWRMLSDE
:: ******::* ***...: .. * **
MMAR_1418|M.marinum_M YASAANELTAMLGAVQAGPWEGSSAEQYVAAHLPYVAWLMQASVDTTQAA
MUL_1202|M.ulcerans_Agy99 YASVADELMGVLAAVQGGAWEGLSAELYVAAHVPYLMWLMRASATSAQAA
Mflv_0325|M.gilvum_PYR-GCK YASAAAELTSILAGVQSGAWEGPSSQQYVAAHTPYLAWLAQQSAVSAATA
Mvan_0415|M.vanbaalenii_PYR-1 YAAAAAELSSILADVQAGAWEGPSSEQYVAAHTPYLAWLAQQSAAGAAAA
MSMEG_0619|M.smegmatis_MC2_155 YAAAAAELTSVLSAVQAGSWEGPSSEQYVAAHAPYLQWLAQQSANSAAAA
MAB_4783|M.abscessus_ATCC_1997 YSSAANELTTTLGSVRAGVWDGASAEQYQTAHVPYLSWLHETSAVSAGVA
Mb0262c|M.bovis_AF2122/97 YAETADELAALLAAVQAGTWDGPTAAVYVAAHTPYLAWLVQASANSAAMA
Rv0256c|M.tuberculosis_H37Rv YAETADELAALLAAVQAGTWDGPTAAVYVAAHTPYLAWLVQASANSAAMA
MLBr_01828|M.leprae_Br4923 YAEMADELVALLVVVPVSSWDGSAAEAYVIAYLPYLGWLRQASVDSAVMA
MAV_1329|M.avium_104 YAESADELVTLLGAVRAGDWDGPTAGAYLAAHAPYLAWLVRASTDSAAVA
TH_3113|M.thermoresistible__bu YRAAAVELAAVVSQTCATAWEGVGADAYAAAHGPYLFWLTDTAAAAAAAG
* * ** : . *:* : * *: **: ** :. : .
MMAR_1418|M.marinum_M AQLETAAAAYTTALAAMPTLPELATNHTIHAALTATNFFGINTIPITLNE
MUL_1202|M.ulcerans_Agy99 AQHEAAAAAYTTALAAMPTMPELAANHVIHGVLMATNFFGINTIPIAANE
Mflv_0325|M.gilvum_PYR-GCK VQHDTAAAAYTTALATMPTLPELALNHTTHAVLVGTNFLGINTIPIALNE
Mvan_0415|M.vanbaalenii_PYR-1 AQHEAAAAAYSTALATMPTLPELALNHTTHAVLVATNFLGINTIPIAMTE
MSMEG_0619|M.smegmatis_MC2_155 VQHETAAAAYSTALATMPTMAELALNHTMHGVLVATNFFGINTIPIALNE
MAB_4783|M.abscessus_ATCC_1997 AQTETAATAYSEALATMPTLGELAANHATHGALVATNFFGINTIPIAVNE
Mb0262c|M.bovis_AF2122/97 TRQETAATAYGTALAAMPTLAELGANHALHGVLMATNFFGINTIPIALNE
Rv0256c|M.tuberculosis_H37Rv TRQETAATAYGTALAAMPTLAELGANHALHGVLMATNFFGINTIPIALNE
MLBr_01828|M.leprae_Br4923 AHYETMATAYITTLAMMPTLAELAANRTAHTVLVTTNFFGINTIPIARNE
MAV_1329|M.avium_104 AQQEVAAAAYTAALAAMPTLPELAANHAAHAVLTATNFFGVNTIPIAVNE
TH_3113|M.thermoresistible__bu AQLEAAAAAHASALAAMPTMAELTANRTTHAALVATNFFGVNTIPIAVNE
.: :. *:*: :** ***: ** *:. * .* ***:*:*****: .*
MMAR_1418|M.marinum_M ADYVRMWIQAATTMSTYQAVSGTALASTPQTAPAPYILKSNAQTEDSQPP
MUL_1202|M.ulcerans_Agy99 ADYVRMWIQAATTMSTYQAVSAAAVASTPPSTPAPRILAAPAAAHDHDHD
Mflv_0325|M.gilvum_PYR-GCK ADYVRMWIQAATTMATYQSVSGAALAATPTSAPAPSVLLPGVGEAGRAA-
Mvan_0415|M.vanbaalenii_PYR-1 ADYVRMWIQAATTMATYQAVSGAALAATPTATPAPFVLAPGVGEAGRAA-
MSMEG_0619|M.smegmatis_MC2_155 ADYVRMWIQAATTMSTYQAVSGAAVAAAPVSAPAPFLLKPGVGEAGSAS-
MAB_4783|M.abscessus_ATCC_1997 ADYIRMWIQAATVMSTYQAVSESSVSAAPPTSPAPPVLSPDSGAAART--
Mb0262c|M.bovis_AF2122/97 SDYARMWIQAATTMASYQAVSTAAVAAAPQTTPAPQIVKANAPTAASDEP
Rv0256c|M.tuberculosis_H37Rv SDYARMWIQAATTMASYQAVSTAAVAAAPQTTPAPQIVKANAPTAASDEP
MLBr_01828|M.leprae_Br4923 IDYVRMWVEAAIAMGTYQEVSTVVVDSAPEAIAAPQIMASDALEASSDQP
MAV_1329|M.avium_104 ADYARMWVQAATVMGTYQDVAAAALAATPHTEPAPRVMAAAAPAATAAQS
TH_3113|M.thermoresistible__bu ADYARMWIQAATTMATYEAVASAAVSATPRTVAPPPILGAGTGESATAAI
** ***::** .*.:*: *: : ::* : ..* :: .
MMAR_1418|M.marinum_M VEGS----------------------------------------------
MUL_1202|M.ulcerans_Agy99 HGGDP---------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4783|M.abscessus_ATCC_1997 --------------------------------------------------
Mb0262c|M.bovis_AF2122/97 N--------QVQEWLQWLQKIGYTDFYNNVIQPFINWLTNLPFLQAMFSG
Rv0256c|M.tuberculosis_H37Rv N--------QVQEWLQWLQKIGYTDFYNNVIQPFINWLTNLPFLQAMFSG
MLBr_01828|M.leprae_Br4923 SPTAPSQSPQVQNWLQWLQKIGYTDFYNTLVQPLITSLTNHPFFQGMFSG
MAV_1329|M.avium_104 SSYPP---DTQDQWLDWLEKTGFVDFYNRYIQPLIDQLMNNPFFQSLFSG
TH_3113|M.thermoresistible__bu TGAHVT----------------------------------------AELR
MMAR_1418|M.marinum_M -DPLDSLVADILRAITDGRVNWDPVSRTVNGIEYEEYTDAGDPVWWVVRA
MUL_1202|M.ulcerans_Agy99 -TPIDYFVAEVLRIISGGRIIWDPAEGTVNGIPYDDYVNAAQPIWWLVRA
Mflv_0325|M.gilvum_PYR-GCK -ADMSAFAAQPMAAQAGAAFDVSNIIADIIRLYGEVLRFLFEPIFNFLRD
Mvan_0415|M.vanbaalenii_PYR-1 -ADVTAFAAQAQAAEAGSALDLSNIIADLIRAYGELLRFLFEPIFDFLRD
MSMEG_0619|M.smegmatis_MC2_155 -ASVQQMSAQATAAESGSSLDLSSIISDLLNQYLQGVPGG-QAILDFLKD
MAB_4783|M.abscessus_ATCC_1997 -------AAQDATKPPPIVPDPNDPIEMLLKNS-QHFLGMYRALKGLITD
Mb0262c|M.bovis_AF2122/97 FDPWLPSLGNPLTFLSPANIAFALGYPMDIGSYVAFLSQTFAFIGADLAA
Rv0256c|M.tuberculosis_H37Rv FDPWLPSLGNPLTFLSPANIAFALGYPMDIGSYVAFLSQTFAFIGADLAA
MLBr_01828|M.leprae_Br4923 FDPWLPSLGNPLSFLSPFNIAFALGTPMDIGSYVGYLSQTFAFIGADLAA
MAV_1329|M.avium_104 FDPWLPSLGNPLSFLNPFNIAFALGYPMDFGSYFGYLAQMFSFVAADLAA
TH_3113|M.thermoresistible__bu AAESRTLLDEINELIDRLFAPLFPPGFADALPDGLLGTLLAPLLPGATGD
: :
MMAR_1418|M.marinum_M LEFSQDFRTFARLLPTDPQAALQFYGELFLFDYPVHIPQLLTWLSQSPQL
MUL_1202|M.ulcerans_Agy99 LEFGQDFQTFIKELFTNPIGAIEFMVELVLFDWPTHIAQIIQALAQSPQL
Mflv_0325|M.gilvum_PYR-GCK PIG--NTFALITDFLTNPVQALITWGPFLLAVVYQA----VSWVGASILY
Mvan_0415|M.vanbaalenii_PYR-1 PLG--NTIKLITDFLTNPAQALITWGPFLAAVAYQA----VSWVGASILY
MSMEG_0619|M.smegmatis_MC2_155 PLG--NLGRLLTDFMTNPAGALATWWPFLFGVAYQVFFNLVGWPTWGMIF
MAB_4783|M.abscessus_ATCC_1997 PVG--TIVRIIIDFSTNPAAAIVTWTPLFYVFAYAA-----TFAVMGTPI
Mb0262c|M.bovis_AF2122/97 AFASGNPATIAFTLMFTTVEAIGTIITDTIALVKTLLEQTLALLPAALPL
Rv0256c|M.tuberculosis_H37Rv AFASGNPATIAFTLMFTTVEAIGTIITDTIALVKTLLEQTLALLPAALPL
MLBr_01828|M.leprae_Br4923 AFASGNPVTIGFTLLFTTIEAIGTIITDTIALVKTMIEQSFVLLPMILPL
MAV_1329|M.avium_104 AFASGNPATIAWTLLFTTIEVIGTVITDTIALIKTLLEQMIVLIPAILPL
TH_3113|M.thermoresistible__bu GPPMATIMSFLLMGLSNPAYLFPVLVYLLFTGVVHTTVAVSGMLAQLVPL
: . :
MMAR_1418|M.marinum_M LAVALGQ--AVSGLG--AVTGFAGLAGLAAQPIGTVASALGPV----AAP
MUL_1202|M.ulcerans_Agy99 LAVALGG--VVANLG--AISGLAGLSGLAGLHSAALPAAIAPI----APP
Mflv_0325|M.gilvum_PYR-GCK PSLFLLP--LLATT--LAIVAGVGQHLLSLLNTPPAEEAAEEP----APA
Mvan_0415|M.vanbaalenii_PYR-1 PSLLLLP--LVATT--LAIVLGVGAYLLENLPAPAEDAPAEEP----AAS
MSMEG_0619|M.smegmatis_MC2_155 ASPFLIP--ALAALGITGLVLLIDHVLNNPVDVPAEDEAPQEV----AAA
MAB_4783|M.abscessus_ATCC_1997 YAAIMGP--AAGISIPLAITLAS---LSQMPEAPPVDAPAETV----PAR
Mb0262c|M.bovis_AF2122/97 LAAPLAPLTLAPASAAGGFAGLSGLAGLVGIPPSAPPVIPPVA--AIAPS
Rv0256c|M.tuberculosis_H37Rv LAAPLAPLTLAPASAAGGFAGLSGLAGLVGIPPSAPPVIPPVA--AIAPS
MLBr_01828|M.leprae_Br4923 LTAPLA---VATAGAAGSFAGLSELAGLVGVAPPGLPSAPPVA--AVAPV
MAV_1329|M.avium_104 LTVSVVP--LVVPTLVGGLAGLTGLAGLHAIPVPPFVPAPTLVPVALAPS
TH_3113|M.thermoresistible__bu MPALLPVAVAALGGLAGVWAGLSGLAGLAGLTAVPAADGGASAAP-VPAG
. : ..
MMAR_1418|M.marinum_M ADMLPVTSMAPTVTTPVAAPVSATAPAPATALTAGGPPPVPPAAGGAGFS
MUL_1202|M.ulcerans_Agy99 --MPPGVALAPTVAASVAAPTPPSAPPSAASTVANAAPPPPPAPAAAGFG
Mflv_0325|M.gilvum_PYR-GCK QSAPSRPDQQSFPATMSAPPPPSGAPIAANTVSAGSPPAPGAPAAAAATF
Mvan_0415|M.vanbaalenii_PYR-1 SPAPTRADQPSPAIAVSAPPPPSSAAATVGTVATGTAPAPGAPAAATASF
MSMEG_0619|M.smegmatis_MC2_155 P----RTDQP-LAVGISPAGVPGSAATAAAPAPAPAGTTVAAPAPAAATF
MAB_4783|M.abscessus_ATCC_1997 IDQPHAVAMGGAPAPTASTAAP--TPTTTSPATPGSAPAP-TPPPAGAEG
Mb0262c|M.bovis_AF2122/97 IP------TPTPTPAPAPAPTAVTAPTPPPGPPPPPVTAPPPVTGAGIQS
Rv0256c|M.tuberculosis_H37Rv IP------TPTPTPAPAPAPTAVTAPTPPPGPPPPPVTAPPPVTGAGIQS
MLBr_01828|M.leprae_Br4923 VPPSMPTLASIPTPTPMPAPAASTAPVVTP-PGPPPVTAPPSVTGAGVES
MAV_1329|M.avium_104 PPP---APAPAPSPAPAPAPTSAAAPAAAAPGAPPPTPSGPPV--ATLHS
TH_3113|M.thermoresistible__bu GPSLPSGSSAPPAPTGSAAPTTGTAPGGAGSPPPAGHSVPPAPHSAPPVG
.. . :. . . . .
MMAR_1418|M.marinum_M YPYLIGG-GPSIGFGSGMSTSASASAKKKTPEPD---TAAAAAARERARA
MUL_1202|M.ulcerans_Agy99 FPFVVGG-GPGIGYGEGMSASAAASARRKAPEPDSAALAAAAAVREEARR
Mflv_0325|M.gilvum_PYR-GCK VPYVVAGRDPYEGFSPTVRDSTGAKAPAGTIPAAASGIAASAAERRKRRR
Mvan_0415|M.vanbaalenii_PYR-1 VPYAVAGRDPGTGFSPTVRDSTSAKAPASGIPAAASGVAASAAERRKRRR
MSMEG_0619|M.smegmatis_MC2_155 VPYAVANRDPGEGFTPTLGNKSQVAAPASGVPAAASGVAASLASRRKRRR
MAB_4783|M.abscessus_ATCC_1997 LGYAVRGDGPGFGFGPTIGASTGATAHAPSSAVSAAAALACNPATGKSRR
Mb0262c|M.bovis_AF2122/97 FGYLVGDLNSAAQARKAVGTGVRKK-TPEPDSAEAPAAAAAPEEQVQPQR
Rv0256c|M.tuberculosis_H37Rv FGYLVGDLNSAAQARKAVGTGVRKK-TPEPDSAEAPAAAAAPEEQVQPQR
MLBr_01828|M.leprae_Br4923 FGYLVGRLPSTARG--VVGTSVRQQ-SSAPDRIEAPDAAATPQEQARSRW
MAV_1329|M.avium_104 LAYLVGGLTADARR--AANAGVRRREAAAPENVEAP-AVAQPEEESTQRR
TH_3113|M.thermoresistible__bu TSGPPYLIAAQPAPGVARRSAGARRAASIVEPAGSAAAAAAARESAPIRR
. * :
MMAR_1418|M.marinum_M RRRRRATLRGYGDEFMDIEVDPDWGAPPGEGPGASTVASDHGAGPVGIAG
MUL_1202|M.ulcerans_Agy99 RRRKRKTERGYGEEFMDVEVDPDWGGPLDDEP----VASTQGAGRLGFAG
Mflv_0325|M.gilvum_PYR-GCK RQKEEIKGRGYADAYADYEELPDDGPPEQPAPR--VTASTRGAGPMGFAG
Mvan_0415|M.vanbaalenii_PYR-1 RQKDEIAGRAYADAYADYEPEPDDEPPVRQEPR--IAATERGAGPMGFAG
MSMEG_0619|M.smegmatis_MC2_155 KKGAQIEERGYADAYMDYEE-PDEDPAPQPEPR--VRASERGSDAMGFTG
MAB_4783|M.abscessus_ATCC_1997 RRRRTIDDRGYRHEYATMDDHTPTGP--QDPVT--AVASGTGAGRLGFAG
Mb0262c|M.bovis_AF2122/97 RRRPKIKQLGRGYEYLDLDPETGHDP----------TGSPQGAGTLGFAG
Rv0256c|M.tuberculosis_H37Rv RRRPKIKQLGRGYEYLDLDPETGHDP----------TGSPQGAGTLGFAG
MLBr_01828|M.leprae_Br4923 RRRAKVTPFDS-----SGSPNPKAAP----------TASDQGAGTLGLAG
MAV_1329|M.avium_104 RHRAAAKQLGRGYEYLDPEPST--------------TASQLGAPTLGFAG
TH_3113|M.thermoresistible__bu RRGQKDGLHGHRHEHQQPASMSAATAP-----------SAAGIRVLGGAG
:: . : * :* :*
MMAR_1418|M.marinum_M TVHTGSVTPAAGLTTLGGDDFDGEPRMPMLPGTWDPDGARDAGKGS----
MUL_1202|M.ulcerans_Agy99 TVHSESAATAAGLTTLVADEFGGGPKMPMLPGTWDTDSDAPSD-------
Mflv_0325|M.gilvum_PYR-GCK TVSRG-DEQAGGLTTLAGDSFGGGPREPMLPGTWDPDATDDRHTDGRDGH
Mvan_0415|M.vanbaalenii_PYR-1 TVSRD-AAQAGGLTTLPGDPFGGGPKAPMLPGTWDPDTEPD------ERH
MSMEG_0619|M.smegmatis_MC2_155 TVTRH-DVTAAGLTTLTGDTFDDRPVTPMLPGTWDGDENPAP------SP
MAB_4783|M.abscessus_ATCC_1997 VHTATTAVEATGLSTLDGDAEN--RTIPMLPGTWDVTDDDR---------
Mb0262c|M.bovis_AF2122/97 TTHKASPGQVAGLITLPNDAFGGSPRTPMMPGTWDTDSATRVE-------
Rv0256c|M.tuberculosis_H37Rv TTHKASPGQVAGLITLPNDAFGGSPRTPMMPGTWDTDSATRVE-------
MLBr_01828|M.leprae_Br4923 TARQASSGPATGLVTLSNGTFSDSPRAPMLPRTWGADPTFCYNAADIGPA
MAV_1329|M.avium_104 TAANRAAAAPAGLSAPVLDEFADAPRAPMMPATWDGSKQ-----------
TH_3113|M.thermoresistible__bu RISRTRGSVPHAEITP------GDPTEPSSPTDRAHRPAEPN--------
. : * *
MMAR_1418|M.marinum_M ---------
MUL_1202|M.ulcerans_Agy99 ---------
Mflv_0325|M.gilvum_PYR-GCK DGHDGKEKP
Mvan_0415|M.vanbaalenii_PYR-1 NHHDGKDSQ
MSMEG_0619|M.smegmatis_MC2_155 DDPEGGPRR
MAB_4783|M.abscessus_ATCC_1997 ---------
Mb0262c|M.bovis_AF2122/97 ---------
Rv0256c|M.tuberculosis_H37Rv ---------
MLBr_01828|M.leprae_Br4923 GGWDDE---
MAV_1329|M.avium_104 ---------
TH_3113|M.thermoresistible__bu ---------