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MNFMMLPPEVNSALMFTGAGSAPTLAAATAWDGLVAELGEAAEAFSSVTSGLASGSWQGPAAAAMAAAAA PYAGWLSAAATRALGAATQAKAAAAVFESAQAATVHPELVLANRNQLVSLVLSNLFGQNAPAIAATESTY EELWAQDVAATVGYHGGASAVAAQLAPWQQAIQALPGRVAAMATTGPAASAAAALASGPAAALDIGNNGS GNFLSIGNIGNNNLGSGNTGSANLGGGNIGNGNLGSGNTGNVNLGNGNNGFFNFGNGNLGDTNFGSGNSG NLNLGSGNRFGSGNIGFGNRFGDGNFGSGNAGSYNFGTGNNGSFNIGSGNNGDSNIGFGNLGTNNLGFGN NGSNNIGFGLSGSNQIGIGGLNAGIGNMGFGNAGDNNVGFFNSGSNNIGFFNSGDGNFGFAHAGSTNTGF WNSGGTNTGFGNGGSLNFGFGNGGVENMGHGNAGSFNMGFGNGGGGNTGFYNSGTYNTGFSNAAETNTGW ENSGNVNTGGYNSGGLNTGIGSPDTQAGPNSGFGHSGSGNSGFFNSGDGNSGFENSNTCVSANGHSGVRN SGDATNVGFSNSGSNNTGIFNTGTFNTGIANSGSDSSGLLISGTNSSGALNSGDDQSGFNN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0964 | - | - | 100% (621) | PPE family protein |
| M. ulcerans Agy99 | MUL_0902 | - | 0.0 | 63.59% (629) | PPE family protein |
| M. ulcerans Agy99 | MUL_0965 | - | e-173 | 49.86% (702) | PPE family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1166c | PPE16 | 0.0 | 66.14% (635) | PPE family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-29 | 27.70% (621) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1135c | PPE16 | 0.0 | 66.14% (635) | PPE family protein |
| M. leprae Br4923 | MLBr_01182 | - | 4e-29 | 42.77% (166) | PPE-family protein |
| M. abscessus ATCC 19977 | MAB_0047 | - | 6e-24 | 34.29% (210) | PPE family protein |
| M. marinum M | MMAR_4319 | - | 0.0 | 98.71% (621) | PPE family protein |
| M. avium 104 | MAV_4704 | - | 3e-52 | 54.40% (193) | PPE family protein |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 5e-29 | 28.03% (528) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3569 | - | 2e-26 | 36.59% (205) | PUTATIVE PPE protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 2e-34 | 28.18% (614) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4319|M.marinum_M --------------------------------------------------
Mb1166c|M.bovis_AF2122/97 --------------------------------------------------
Rv1135c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4319|M.marinum_M --------------------------------------------------
Mb1166c|M.bovis_AF2122/97 --------------------------------------------------
Rv1135c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4319|M.marinum_M --------------------------------------------------
Mb1166c|M.bovis_AF2122/97 --------------------------------------------------
Rv1135c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4319|M.marinum_M --------------------------------------------------
Mb1166c|M.bovis_AF2122/97 --------------------------------------------------
Rv1135c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4319|M.marinum_M --------------------------------------------------
Mb1166c|M.bovis_AF2122/97 --------------------------------------------------
Rv1135c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
MUL_0964|M.ulcerans_Agy99 -------------------MN---FMMLPPEVNSALMFTGAGSAP-----
MMAR_4319|M.marinum_M -------------------MN---FMMLPPEVNSALMFTGAGSAP-----
Mb1166c|M.bovis_AF2122/97 -------------------MS---FLVLPPEVNSALMFAGAGSGP-----
Rv1135c|M.tuberculosis_H37Rv -------------------MS---FLVLPPEVNSALMFAGAGSGP-----
MAV_4704|M.avium_104 -------------------MTNPHFAWLPPEVNSALIYSGPGPGP-----
MLBr_01182|M.leprae_Br4923 ---------------------MFDFAALSPETNSTRMYLGPGSSP-----
MAB_0047|M.abscessus_ATCC_1997 -------------------MSAPIWMASPPEVHSALLSAGPGPGA-----
TH_3569|M.thermoresistible__bu ------------------MMTAPIWMALPPEVHSALLSSGPGPGS-----
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
:. : . * .
MUL_0964|M.ulcerans_Agy99 -------------TLAAATAWDGLVAELGEAAEAFSSVTSGLASGSWQGP
MMAR_4319|M.marinum_M -------------TLAAATAWDGLAAELGEAAEAFSSVTSGLASGSWQGP
Mb1166c|M.bovis_AF2122/97 -------------TLAAAAAWDGLAAELGQAANSFSSATAALADTAWQGP
Rv1135c|M.tuberculosis_H37Rv -------------TLAAAAAWDGLAAELGQAANSFSSATAALADTAWQGP
MAV_4704|M.avium_104 -------------LLAAAAAWDGLAEELASSAQSFSSVTSDLASGSWQGA
MLBr_01182|M.leprae_Br4923 -------------ILTAAAAWVVLAKELTAAAQGLQSAVEALLT-TFEGE
MAB_0047|M.abscessus_ATCC_1997 -------------LLAAAAQWQALSTQYATAATELTELLGSTVAGSWQGP
TH_3569|M.thermoresistible__bu -------------LLAAASAWHALSAEYASAAAELSSVLANVQAGSWEGP
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
: . :: .
MUL_0964|M.ulcerans_Agy99 AAAAMAAAAAPYAGWLSAAATRALGAATQAKAAAA---------------
MMAR_4319|M.marinum_M AAAAMAAAAAPYAGWLSAAATRALGAATQAKAAAA---------------
Mb1166c|M.bovis_AF2122/97 AATAMAAAAAPYASWLSTAATRALSAAAQAKAAAA---------------
Rv1135c|M.tuberculosis_H37Rv AATAMAAAAAPYASWLSTAATRALSAAAQAKAAAA---------------
MAV_4704|M.avium_104 SSAAMMTVANQYVSWLSAAAAQAEEVSHQASAIAT---------------
MLBr_01182|M.leprae_Br4923 SAAALAERVTPYEKWLTQNAASAELTATQLTVAAN---------------
MAB_0047|M.abscessus_ATCC_1997 SAMQYAASHAPYLAWLTQQSAMSATNAVLHETSAA---------------
TH_3569|M.thermoresistible__bu SAERYVAAHAPYLAWLTQQSANSAATAGRHETAAA---------------
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
: .: . : .
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4319|M.marinum_M --------------------------------------------------
Mb1166c|M.bovis_AF2122/97 --------------------------------------------------
Rv1135c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
MUL_0964|M.ulcerans_Agy99 ----VFESAQAATVHPELVLANRNQLVSLVLSNLFGQNAPAIAATESTYE
MMAR_4319|M.marinum_M ----VFESAQAATVHPELVLANRNQLVSLVLSNLFGQNAPAIAATESTYE
Mb1166c|M.bovis_AF2122/97 ----VYEAARAATVDPLLVAANRHQLVSLVLSNLFGQNAPAIAATEAAYE
Rv1135c|M.tuberculosis_H37Rv ----VYEAARAATVDPLLVAANRHQLVSLVLSNLFGQNAPAIAATEAAYE
MAV_4704|M.avium_104 ----AFEVALAATVQPAVVAANRALVQALAATNWLGQNTPAIADIEAAYE
MLBr_01182|M.leprae_Br4923 ----AYETAFTMTVPPLMVFVNRAQACLLIMSNIFGQNSTAIAEKEAEYT
MAB_0047|M.abscessus_ATCC_1997 ----AYTTALAAMPTLAELAANHMIHGVLLATNFFGINTIPIALNEADYI
TH_3569|M.thermoresistible__bu ----AYSTALATMPTMAELTLNKTTHAVLVATNFLGINTIPIALNEADYV
Mflv_5091|M.gilvum_PYR-GCK -AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAAGGAGGLG
Mvan_1264|M.vanbaalenii_PYR-1 -VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAAGQAGTAG
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
. . . . : .
MUL_0964|M.ulcerans_Agy99 ELWAQDVAATVG--------------------------------------
MMAR_4319|M.marinum_M ELWAQDVAAMVG--------------------------------------
Mb1166c|M.bovis_AF2122/97 QLWAADVAAMVS--------------------------------------
Rv1135c|M.tuberculosis_H37Rv QLWAADVAAMVS--------------------------------------
MAV_4704|M.avium_104 QMWASDVAAMFG--------------------------------------
MLBr_01182|M.leprae_Br4923 EMWIQDAAAMTS--------------------------------------
MAB_0047|M.abscessus_ATCC_1997 RMWIQAATTMGV--------------------------------------
TH_3569|M.thermoresistible__bu RMWIQAATSMST--------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ETGTTGGAGGVG--------------------GQGTAGGTGGVGGIGGAG
Mvan_1264|M.vanbaalenii_PYR-1 ETGVTGGVGGIG--------------------GQGTEGGTGGVGGVGGVG
MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4319|M.marinum_M --------------------------------------------------
Mb1166c|M.bovis_AF2122/97 --------------------------------------------------
Rv1135c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------STGAVGG-------VGGKG----IQGGQG-----------
Mvan_1264|M.vanbaalenii_PYR-1 ----------ATGGAGG-------VGGKG----IQGGQG-----------
MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
MUL_0964|M.ulcerans_Agy99 --YHGGASAVAAQLAPWQQAIQALP-------------------------
MMAR_4319|M.marinum_M --YHGGASAVAAQLAPWQQAIQALP-------------------------
Mb1166c|M.bovis_AF2122/97 --YHSGASAVAAQLAPWAQAVRALP-------------------------
Rv1135c|M.tuberculosis_H37Rv --YHSGASAVAAQLAPWAQAVRALP-------------------------
MAV_4704|M.avium_104 --YHADASAAVAKLPPWNEVLQNLG-------------------------
MLBr_01182|M.leprae_Br4923 --YQASVLEAVGATKAFTAPPLGVN-------------------------
MAB_0047|M.abscessus_ATCC_1997 --YQGVSSAALAATTPTQPSPMIMA-------------------------
TH_3569|M.thermoresistible__bu --YQAVAGTAVMSAPASSPAPLLLA-------------------------
Mflv_5091|M.gilvum_PYR-GCK --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK
Mvan_1264|M.vanbaalenii_PYR-1 --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK
MSMEG_0868|M.smegmatis_MC2_155 KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV
:.
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4319|M.marinum_M --------------------------------------------------
Mb1166c|M.bovis_AF2122/97 --------------------------------------------------
Rv1135c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGRGGLFG---------------KGGNAGNGAD-----------
Mvan_1264|M.vanbaalenii_PYR-1 GGNGGNGGRGSLFG---------------RGGNAGNGGN-----------
MSMEG_0868|M.smegmatis_MC2_155 GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP
MUL_0964|M.ulcerans_Agy99 -----------GRVAAMATTGPAASAAAALASGPAAALDIGNNGSGNFLS
MMAR_4319|M.marinum_M -----------GRVAAMATTGPAASAAAALASGPAAALGIGNNGSGNFLS
Mb1166c|M.bovis_AF2122/97 -----------NPTAPALASGPAALAIPALG--------IGNTGIGNIFS
Rv1135c|M.tuberculosis_H37Rv -----------NPTAPALASGPAALAIPALG--------IGNTGIGNIFS
MAV_4704|M.avium_104 -----------FSNASTAVTRPAGSGAVARG-------------------
MLBr_01182|M.leprae_Br4923 -----------EVGLAQEVVEEVVEEVVEEV-------------------
MAB_0047|M.abscessus_ATCC_1997 -----------PGG-EMSRMSADMMSMAAQP-------------------
TH_3569|M.thermoresistible__bu -----------PGVSEAADAMATTQQIGSQA-------------------
Mflv_5091|M.gilvum_PYR-GCK -----------GGTGGAGGAGGTGG-TGGAGGTGG---------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------GGTGGNGGNGGTGG-TGGNGGTGG---------------
MSMEG_0868|M.smegmatis_MC2_155 AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ
MUL_0964|M.ulcerans_Agy99 IGNIGNNNLGSGNTGSANLGGGNIGNGNLGSGNTGNVNLGNGNNGFFNFG
MMAR_4319|M.marinum_M IGNIGNNNLGSGNTGSANLGGGNIGNGNLGSGNTGNVNLGNGNNGFFNFG
Mb1166c|M.bovis_AF2122/97 IGNIGDYNLGNGNTGNANLGSGNTGQANLGSGNTGFFNFGSGNTANTNFG
Rv1135c|M.tuberculosis_H37Rv IGNIGDYNLGNGNTGNANLGSGNTGQANLGSGNTGFFNFGSGNTANTNFG
MAV_4704|M.avium_104 ----------------------------YTSRIAGFLAPRAPQ-------
MLBr_01182|M.leprae_Br4923 -------------VEAEQAISQAALDQAVNEGMEATVVPQVDQQVNVDVA
MAB_0047|M.abscessus_ATCC_1997 -----------QAAESGSALDSS----------NNIMDQLMR----FMTN
TH_3569|M.thermoresistible__bu -----------TAADSGTALNLSDLIANLLQYYQDYLDQLFGPIVDFLRD
Mflv_5091|M.gilvum_PYR-GCK --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
Mvan_1264|M.vanbaalenii_PYR-1 --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
MSMEG_0868|M.smegmatis_MC2_155 TDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRG
MUL_0964|M.ulcerans_Agy99 NGNLGDTNFGSGNSGNLNLGSGNRFGSGNIGFGNRFGDGNFGSGNAGSYN
MMAR_4319|M.marinum_M NGNLGDTNFGSGNSGNLNLGSGNRFGSGNIGFGNRFGDGNFGSGNAGSYN
Mb1166c|M.bovis_AF2122/97 SGNLGNLNLGSGNDGNGNFGLGN-IGDGNRGSGN-VGSFNFGTANAGSFN
Rv1135c|M.tuberculosis_H37Rv SGNLGNLNLGSGNDGNGNFGLGN-IGDGNRGSGN-VGSFNFGTANAGSFN
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 TPQTAVP--------------------------------DSSSAAAPQLW
MAB_0047|M.abscessus_ATCC_1997 P-------------------------------------LGTLQDMIEDFM
TH_3569|M.thermoresistible__bu P-------------------------------------IGNLFQLIDDFL
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGG
MUL_0964|M.ulcerans_Agy99 FG------------------------------------------------
MMAR_4319|M.marinum_M FG------------------------------------------------
Mb1166c|M.bovis_AF2122/97 VG------------------------------------------------
Rv1135c|M.tuberculosis_H37Rv VG------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 GG------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997 RN------------------------------------------------
TH_3569|M.thermoresistible__bu TN------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AG-----------DGTGGTGGTGG----TGGQGGQGGQGG----------
Mvan_1264|M.vanbaalenii_PYR-1 AG-----------DGLGGTGGTGG----TGGFGGQGGQGG----------
MSMEG_0868|M.smegmatis_MC2_155 AGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIG
MUL_0964|M.ulcerans_Agy99 -------TGNNGSFNIGSGNNGDSN----------------------IGF
MMAR_4319|M.marinum_M -------TGNNGSFNIGSGNNGDSN----------------------IGF
Mb1166c|M.bovis_AF2122/97 -------SANHGSPNVGFANLGNNN----------------------LGI
Rv1135c|M.tuberculosis_H37Rv -------SANHGSPNVGFANLGNNN----------------------LGI
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 -------FAQHLSPINDTLSMINNH----------------------AGM
MAB_0047|M.abscessus_ATCC_1997 -------PVAAFFAWFPLLFFIAYE----------------------AFF
TH_3569|M.thermoresistible__bu -------PAGALVTWWPLLFAVAYQ----------------------VFT
Mflv_5091|M.gilvum_PYR-GCK -------TGGTGGQGG-LGGGGGTG-----------------------GQ
Mvan_1264|M.vanbaalenii_PYR-1 -------TGGTGGQGG-LGGVGGTG-----------------------GT
MSMEG_0868|M.smegmatis_MC2_155 SNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGH
MUL_0964|M.ulcerans_Agy99 GNLGTNNLGFGNNGSNNIGFGLSGSNQIGIGGLNAGIGNMGFGNAGDNNV
MMAR_4319|M.marinum_M GNFGTNNLGFGNNGSNNIGFGLSGSNQIGIGGLNAGIGNMGFGNAGDNNV
Mb1166c|M.bovis_AF2122/97 ANLGNNNLGIANLGNNNIGIGLTGDNMIGIGALNSGIGNLGFGNSGNNNI
Rv1135c|M.tuberculosis_H37Rv ANLGNNNLGIANLGNNNIGIGLTGDNMIGIGALNSGIGNLGFGNSGNNNI
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 ANAGLSLVNGMGSAMKSLAPTTTKAAESAFKAMGSAVQSTGRGLLGSSSG
MAB_0047|M.abscessus_ATCC_1997 IPFGFTFWGVLLSAPAWLPIVLGLALSALVPPAGIEEP-GQEDEPGREPT
TH_3569|M.thermoresistible__bu NLVGWPTWAMILASPVLIPLAITLGVAGLVMIADQAQPPAEEAAPEEDVA
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGS
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGV
MSMEG_0868|M.smegmatis_MC2_155 GGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGD
MUL_0964|M.ulcerans_Agy99 GFFNSGSNNIGFFNSGDGNFGFAHAGSTNTGFWNSGGTNTGFGNGGSLNF
MMAR_4319|M.marinum_M GFFNSGSNNIGFFNSGDGNFGFANAGSTNTGFWNSGGTNTGFGNGGSLNF
Mb1166c|M.bovis_AF2122/97 GLFNSGNNNIGFFNSGDSNFGFFNSGDTNTGFGNAGFTNTGFGNAGSGNF
Rv1135c|M.tuberculosis_H37Rv GLFNSGNNNIGFFNSGDSNFGFFNSGDTNTGFGNAGFTNTGFGNAGSGNF
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 GHVTAQLGRAASIGSLRVPQTWTTASQPVTAATRALSPAR----------
MAB_0047|M.abscessus_ATCC_1997 RIERRSPQQDLQLAHVPSGSPTPGGSTTTTVTSGGSAPPAPAPATATPAY
TH_3569|M.thermoresistible__bu APVRAEPQNPLPLTXXX---------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGKA
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGTA
MSMEG_0868|M.smegmatis_MC2_155 GVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTL
MUL_0964|M.ulcerans_Agy99 GFGNGGVENMGHGNAGSFNMGFGNGGGGNTGFYNSGTYNTGFSNAAETNT
MMAR_4319|M.marinum_M GFGNGGVENMGHGNAGSFNMGFGNGGGGNTGFYNSGTYNTGFSNAGETNT
Mb1166c|M.bovis_AF2122/97 GFGNAGNNNFGFGNSGFENMGVGNSGAYNTGSFNSGTLNTGDLNSGDFNT
Rv1135c|M.tuberculosis_H37Rv GFGNAGNNNFGFGNSGFENMGVGNSGAYNTGSFNSGTLNTGDLNSGDFNT
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 -----------------------------------VAVATESESAPLLGG
MAB_0047|M.abscessus_ATCC_1997 MVYAVQEDPPAARFGPTLNEGSGAKAPAAGISAAAAAAASARSRARRKRA
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGATG
Mvan_1264|M.vanbaalenii_PYR-1 GVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGSAG
MSMEG_0868|M.smegmatis_MC2_155 GGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGG
MUL_0964|M.ulcerans_Agy99 GWENSGNVNTGG------------------YNSGGLNTGIGSPDTQAGPN
MMAR_4319|M.marinum_M GWENSGNVNTGG------------------YNSGGLNTGIGSPDTQAGPN
Mb1166c|M.bovis_AF2122/97 GWANSGDINTGG------------------FHSGDLNTGFGSPVDQPVMN
Rv1135c|M.tuberculosis_H37Rv GWANSGDINTGG------------------FHSGDLNTGFGSPVDQPVMN
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 GLPMAPMVPGGG------------------SGTGGVNTALRLQPRAFVMP
MAB_0047|M.abscessus_ATCC_1997 ARIKDPAPQFMD------------------MNS---SVAPDFSESAARQT
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA
Mvan_1264|M.vanbaalenii_PYR-1 SAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA
MSMEG_0868|M.smegmatis_MC2_155 AATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWV
MUL_0964|M.ulcerans_Agy99 SGFGHSGSGNSGFFNSGDGNSGFENSNTCVSANGHSGVRNSGD-------
MMAR_4319|M.marinum_M SGFGHSGSGNSGFFNSGDGNSGFQNSNTGVSANGHSGVRNSGD-------
Mb1166c|M.bovis_AF2122/97 SGFGNIGTGNSGFNNSGDANSGFQNTNTGAFFIGHSGLLNSGG-------
Rv1135c|M.tuberculosis_H37Rv SGFGNIGTGNSGFNNSGDANSGFQNTNTGAFFIGHSGLLNSGG-------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 RNPAAG--------------------------------------------
MAB_0047|M.abscessus_ATCC_1997 TGVGASARGAGRLGFAGTAPAAAGTTAAAGLVERDSGTAEALD-------
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG-------
Mvan_1264|M.vanbaalenii_PYR-1 GATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG-------
MSMEG_0868|M.smegmatis_MC2_155 QAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKS
MUL_0964|M.ulcerans_Agy99 ------ATNVGFSNSGS-NNTGIFNTGTFNTGIANSGS-----DSSGLLI
MMAR_4319|M.marinum_M ------ATNVGFSNSGS-NNTGIFNTGTFNTGIANSGS-----DSSGLLI
Mb1166c|M.bovis_AF2122/97 ------GQHVGISNSGTGFNTGLFNTGFNNTGIGNSATNAAFTTTSGVAN
Rv1135c|M.tuberculosis_H37Rv ------GQHVGISNSGTGFNTGLFNTGFNNTGIGNSATNAAFTTTSGVAN
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_0047|M.abscessus_ATCC_1997 ------GARTVPMLPTSWGTDSEHGPDRPAEGGSST--------------
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG-
Mvan_1264|M.vanbaalenii_PYR-1 ----AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG-
MSMEG_0868|M.smegmatis_MC2_155 GGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGN
MUL_0964|M.ulcerans_Agy99 SGTNSSGALNSGDDQSGFNN-------
MMAR_4319|M.marinum_M SGTNSSGALNSGDDQSGFNN-------
Mb1166c|M.bovis_AF2122/97 SGDNSSGGFNAGNDQSGFFDG------
Rv1135c|M.tuberculosis_H37Rv SGDNSSGGFNAGNDQSGFFDG------
MAV_4704|M.avium_104 ---------------------------
MLBr_01182|M.leprae_Br4923 ---------------------------
MAB_0047|M.abscessus_ATCC_1997 ---------------------------
TH_3569|M.thermoresistible__bu ---------------------------
Mflv_5091|M.gilvum_PYR-GCK -GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 -GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGGNGGADGTPGTAGTTGANNP