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NFAVLPPEINSVRMFSGAGSEPMLAAAAAWDGLSAELGEAAESFASVTSGLAGAGQAWQGAAASAMVAAA GPYASWLGAAAARAAGASASAKVVASAFEAARAAMVHPLAVAANRNGFVQLVMSNLFGQNAPAIAAAEGV YEEMWAADVAAMAGYHGGASAAAAQLSSWQGMVSGVLSGVPGVSGLVGGAAPAAAAVTTPLASAQLGVQA LGSSAAAAPAAVSQELSDLIFNLGIGNVGTFNLGSGNLGNTNLGSGNVGNQNVGSGNYGSGNWGGGNTGT GNTGSGNAGDYNFGSGNFGSGNLGSGNIGSLNLGSGNFGTLNLFGGNNGDLGLGSGNTGDVNVGSGNNGG GNIGFGNLGDNNIGFGNKGSGNIGFGLTGDGQFGIGGFNSGTGNIGLFNSGNNNIGFFNSGDNNFGWCNS GSGNTGFGNAGNFNTGFWNAGSSNTGFGSAGDGNFGLFNAGNHNSGSFNVGTESTGFGNSGAGNTGFMNA GNSNTGAFNGGNVNTGFFNGGNTNTGAFNGGDLNTAIGSSVSQSGLNSGFGNLGSGNSGFYNSDPNGSAN SGFFNTGIGNSGVSNAGPALVPGYNSGFGNIGTNNAGFVNSGNRLAGISNSGDDSSGFLNSGDQNSGGFN SGTGLSGFFR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3666 | - | - | 100% (641) | PPE family protein |
| M. marinum M | MMAR_3665 | - | 0.0 | 72.23% (641) | PPE family protein |
| M. marinum M | MMAR_4319 | - | 0.0 | 58.67% (646) | PPE family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2377c | PPE40 | 0.0 | 72.27% (642) | PPE family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 8e-30 | 25.94% (636) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv2356c | PPE40 | 0.0 | 72.27% (642) | PPE family protein |
| M. leprae Br4923 | MLBr_01182 | - | 2e-28 | 40.34% (176) | PPE-family protein |
| M. abscessus ATCC 19977 | MAB_4284c | - | 3e-23 | 30.79% (432) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4704 | - | 1e-47 | 50.25% (203) | PPE family protein |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 9e-28 | 26.16% (646) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3569 | - | 3e-25 | 33.19% (229) | PUTATIVE PPE protein |
| M. ulcerans Agy99 | MUL_0964 | - | 0.0 | 57.12% (646) | PPE family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 5e-32 | 29.04% (668) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2377c|M.bovis_AF2122/97 --------------------------------------------------
Rv2356c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3666|M.marinum_M --------------------------------------------------
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3569|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2377c|M.bovis_AF2122/97 --------------------------------------------------
Rv2356c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3666|M.marinum_M --------------------------------------------------
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3569|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2377c|M.bovis_AF2122/97 --------------------------------------------------
Rv2356c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3666|M.marinum_M --------------------------------------------------
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3569|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP
Mb2377c|M.bovis_AF2122/97 --------------------------------------------------
Rv2356c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3666|M.marinum_M --------------------------------------------------
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3569|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------VEAASYVADP
Mb2377c|M.bovis_AF2122/97 ----------------------------------------MVN--FSVLP
Rv2356c|M.tuberculosis_H37Rv ----------------------------------------MVN--FSVLP
MMAR_3666|M.marinum_M -----------------------------------------MN--FAVLP
MUL_0964|M.ulcerans_Agy99 -----------------------------------------MN--FMMLP
MAV_4704|M.avium_104 ----------------------------------------MTNPHFAWLP
MLBr_01182|M.leprae_Br4923 ----------------------------------------MFD--FAALS
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3569|M.thermoresistible__bu ---------------------------------------MMTAPIWMALP
MAB_4284c|M.abscessus_ATCC_199 -------------------------EAALANAGLSAVSAAQVGAVMPVVA
Mb2377c|M.bovis_AF2122/97 PEIN---SGRMFFGAGSGPMLAAAAAWDGLAAELGLAAESFGLVTSGLAG
Rv2356c|M.tuberculosis_H37Rv PEIN---SGRMFFGAGSGPMLAAAAAWDGLAAELGLAAESFGLVTSGLAG
MMAR_3666|M.marinum_M PEIN---SVRMFSGAGSEPMLAAAAAWDGLSAELGEAAESFASVTSGLAG
MUL_0964|M.ulcerans_Agy99 PEVN---SALMFTGAGSAPTLAAATAWDGLVAELGEAAEAFSSVTSGLAS
MAV_4704|M.avium_104 PEVN---SALIYSGPGPGPLLAAAAAWDGLAEELASSAQSFSSVTSDLAS
MLBr_01182|M.leprae_Br4923 PETN---STRMYLGPGSSPILTAAAAWVVLAKELTAAAQGLQSAVEALLT
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3569|M.thermoresistible__bu PEVH---SALLSSGPGPGSLLAAASAWHALSAEYASAAAELSSVLANVQA
MAB_4284c|M.abscessus_ATCC_199 ESVA---SNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLS
. . .
Mb2377c|M.bovis_AF2122/97 G-------------SGQAWQGAAAAAMVVAAAPYAGWLAAAAARAGGAAV
Rv2356c|M.tuberculosis_H37Rv G-------------SGQAWQGAAAAAMVVAAAPYAGWLAAAAARAGGAAV
MMAR_3666|M.marinum_M --------------AGQAWQGAAASAMVAAAGPYASWLGAAAARAAGASA
MUL_0964|M.ulcerans_Agy99 ----------------GSWQGPAAAAMAAAAAPYAGWLSAAATRALGAAT
MAV_4704|M.avium_104 ----------------GSWQGASSAAMMTVANQYVSWLSAAAAQAEEVSH
MLBr_01182|M.leprae_Br4923 -----------------TFEGESAAALAERVTPYEKWLTQNAASAELTAT
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3569|M.thermoresistible__bu G----------------SWEGPSAERYVAAHAPYLAWLTQQSANSAATAG
MAB_4284c|M.abscessus_ATCC_199 P-------------RDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFN
.
Mb2377c|M.bovis_AF2122/97 QAKAVAGAFEAARAAMVDPVVVAANRSAFVQLVLSN-------------V
Rv2356c|M.tuberculosis_H37Rv QAKAVAGAFEAARAAMVDPVVVAANRSAFVQLVLSN-------------V
MMAR_3666|M.marinum_M SAKVVASAFEAARAAMVHPLAVAANRNGFVQLVMSN-------------L
MUL_0964|M.ulcerans_Agy99 QAKAAAAVFESAQAATVHPELVLANRNQLVSLVLSN-------------L
MAV_4704|M.avium_104 QASAIATAFEVALAATVQPAVVAANRALVQALAATN-------------W
MLBr_01182|M.leprae_Br4923 QLTVAANAYETAFTMTVPPLMVFVNRAQACLLIMSN-------------I
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3569|M.thermoresistible__bu RHETAAAAYSTALATMPTMAELTLNKTTHAVLVATN-------------F
MAB_4284c|M.abscessus_ATCC_199 RGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGP-------------I
Mb2377c|M.bovis_AF2122/97 FGQNAPAIAAAEATYEQMWAADVAAMVGYHGGAS-AAAALAPWQ------
Rv2356c|M.tuberculosis_H37Rv FGQNAPAIAAAEATYEQMWAADVAAMVGYHGGASAAAAALAPWQ------
MMAR_3666|M.marinum_M FGQNAPAIAAAEGVYEEMWAADVAAMAGYHGGASAAAAQLSSWQGMVSGV
MUL_0964|M.ulcerans_Agy99 FGQNAPAIAATESTYEELWAQDVAATVGYHGGASAVAAQLAPWQ------
MAV_4704|M.avium_104 LGQNTPAIADIEAAYEQMWASDVAAMFGYHADASAAVAKLPPWN------
MLBr_01182|M.leprae_Br4923 FGQNSTAIAEKEAEYTEMWIQDAAAMTSYQASVLEAVGATKAFT------
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
TH_3569|M.thermoresistible__bu LGINTIPIALNEADYVRMWIQAATSMSTYQAVAGTAVMSAPASS------
MAB_4284c|M.abscessus_ATCC_199 ASGQGSTAVNGDVRDSNIINADHGSNVGVDQSQTRVGGDYTNVSG-----
. .
Mb2377c|M.bovis_AF2122/97 -QAVPGLSGLLGGAANAP---------------------AAAAQGAAQGL
Rv2356c|M.tuberculosis_H37Rv -QAVPGLSGLLGGAANAP---------------------AAAAQGAAQGL
MMAR_3666|M.marinum_M LSGVPGVSGLVGGAAPAAAAVTTPLASAQLGVQALGSSAAAAPAAVSQEL
MUL_0964|M.ulcerans_Agy99 -QAIQALPGRVAAMATTG------------------PAASAAAALASGPA
MAV_4704|M.avium_104 -----------------------------------------------EVL
MLBr_01182|M.leprae_Br4923 ----------------------------------------------APPL
Mflv_5091|M.gilvum_PYR-GCK -AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAAGGAGGLG
Mvan_1264|M.vanbaalenii_PYR-1 -VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAAGQAGTAG
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
TH_3569|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --HGSADIDKSVTVVDDHSQRNTTNIN-------DSFNTDRSTNIGSGNT
Mb2377c|M.bovis_AF2122/97 AELTLN--------------------------------------------
Rv2356c|M.tuberculosis_H37Rv AELTLN--------------------------------------------
MMAR_3666|M.marinum_M SDLIFN--------------------------------------------
MUL_0964|M.ulcerans_Agy99 AALDIGNNGSGN--------------------------------------
MAV_4704|M.avium_104 QN------------------------------------------------
MLBr_01182|M.leprae_Br4923 GVNEVG--------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ETGTTGGAGGVG--------------------GQGTAGGTGGVGGIGGAG
Mvan_1264|M.vanbaalenii_PYR-1 ETGVTGGVGGIG--------------------GQGTEGGTGGVGGVGGVG
MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
TH_3569|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TNTEIGSHNQAN--------------------------------------
Mb2377c|M.bovis_AF2122/97 --------------------------------------------------
Rv2356c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3666|M.marinum_M --------------------------------------------------
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------STGAVGG-------VGGKG----IQGGQG-----------
Mvan_1264|M.vanbaalenii_PYR-1 ----------ATGGAGG-------VGGKG----IQGGQG-----------
MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
TH_3569|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2377c|M.bovis_AF2122/97 --------------------------------------------------
Rv2356c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3666|M.marinum_M --------------------------------------------------
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK
Mvan_1264|M.vanbaalenii_PYR-1 --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK
MSMEG_0868|M.smegmatis_MC2_155 KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV
TH_3569|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2377c|M.bovis_AF2122/97 --------------------------------------------------
Rv2356c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3666|M.marinum_M --------------------------------------------------
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGRGGLFG---------------KGGNAGNGAD-----------
Mvan_1264|M.vanbaalenii_PYR-1 GGNGGNGGRGSLFG---------------RGGNAGNGGN-----------
MSMEG_0868|M.smegmatis_MC2_155 GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP
TH_3569|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2377c|M.bovis_AF2122/97 -----------------LGVGNIGSLNLGSGNIGG---------------
Rv2356c|M.tuberculosis_H37Rv -----------------LGVGNIGSLNLGSGNIGG---------------
MMAR_3666|M.marinum_M -----------------LGIGNVGTFNLGSGNLGN---------------
MUL_0964|M.ulcerans_Agy99 ----------------FLSIGNIGNNNLGSGNTGS---------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -----------GGTGGAGGAGGTGG-TGGAGGTGG---------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------GGTGGNGGNGGTGG-TGGNGGTGG---------------
MSMEG_0868|M.smegmatis_MC2_155 AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ
TH_3569|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------IGTSTSAGGSAAVGGNAG---------------
Mb2377c|M.bovis_AF2122/97 --TNVGSGNVGGTNLGSGNYGSLNWGSGNTGTGNAGSGNTGDYNPGSGNF
Rv2356c|M.tuberculosis_H37Rv --TNVGSGNVGGTNLGSGNYGSLNWGSGNTGTGNAGSGNTGDYNPGSGNF
MMAR_3666|M.marinum_M --TNLGSGNVGNQNVGSGNYGSGNWGGGNTGTGNTGSGNAGDYNFGSGNF
MUL_0964|M.ulcerans_Agy99 --ANLGGGNIGNGNLGSGNTGNVNLGNGNNGFFNFGNGNLGDTNFGSGNS
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
Mvan_1264|M.vanbaalenii_PYR-1 --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
MSMEG_0868|M.smegmatis_MC2_155 TDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRG
TH_3569|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --LAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAG
Mb2377c|M.bovis_AF2122/97 GSGNFGSGN-IGSLNVGSGN-FGTLNLANGNNGDVNFGGGNTGDFNFGGG
Rv2356c|M.tuberculosis_H37Rv GSGNFGSGN-IGSLNVGSGN-FGTLNLANGNNGDVNFGGGNTGDFNFGGG
MMAR_3666|M.marinum_M GSGNLGSGN-IGSLNLGSGN-FGTLNLFGGNNGDLGLGSGNTGDVNVGSG
MUL_0964|M.ulcerans_Agy99 GNLNLGSGNRFGSGNIGFGNRFGDGNFGSGNAGSYNFGTGNNGSFNIGSG
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGG
TH_3569|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGNAG--LAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAG
Mb2377c|M.bovis_AF2122/97 NNGTLNFGFGNTGSGNFGFGNTGNNNIGIGLTGDGQIGIGGL--------
Rv2356c|M.tuberculosis_H37Rv NNGTLNFGFGNTGSGNFGFGNTGNNNIGIGLTGDGQIGIGGL--------
MMAR_3666|M.marinum_M NNGGGNIGFGNLGDNNIGFGNKGSGNIGFGLTGDGQFGIGGF--------
MUL_0964|M.ulcerans_Agy99 NNGDSNIGFGNLGTNNLGFGNNGSNNIGFGLSGSNQIGIGGL--------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AG-----------DGTGGTGGTGG----TGGQGGQGGQGG----------
Mvan_1264|M.vanbaalenii_PYR-1 AG-----------DGLGGTGGTGG----TGGFGGQGGQGG----------
MSMEG_0868|M.smegmatis_MC2_155 AGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIG
TH_3569|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGNAGLAGNAGLAGNAGLAGNAAVAGNAAVAGN----------
Mb2377c|M.bovis_AF2122/97 ------------------------------------------------NS
Rv2356c|M.tuberculosis_H37Rv ------------------------------------------------NS
MMAR_3666|M.marinum_M ------------------------------------------------NS
MUL_0964|M.ulcerans_Agy99 ------------------------------------------------NA
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -------TGGTGGQGG-LGGGGGTG-----------------------GQ
Mvan_1264|M.vanbaalenii_PYR-1 -------TGGTGGQGG-LGGVGGTG-----------------------GT
MSMEG_0868|M.smegmatis_MC2_155 SNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGH
TH_3569|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2377c|M.bovis_AF2122/97 GTGNIGFGNSGNNNIGFFNSGDGNIGFFNSGDGNTGFGNAGNINTGFWNA
Rv2356c|M.tuberculosis_H37Rv GTGNIGFGNSGNNNIGFFNSGDGNIGFFNSGDGNTGFGNAGNINTGFWNA
MMAR_3666|M.marinum_M GTGNIGLFNSGNNNIGFFNSGDNNFGWCNSGSGNTGFGNAGNFNTGFWNA
MUL_0964|M.ulcerans_Agy99 GIGNMGFGNAGDNNVGFFNSGSNNIGFFNSGDGNFGFAHAGSTNTGFWNS
MAV_4704|M.avium_104 ----------------------------------LGFSNASTAVTRPAGS
MLBr_01182|M.leprae_Br4923 ------------LAQEVVEEVVEEVVEEVVEAEQAISQAALDQAVNEGME
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGS
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGV
MSMEG_0868|M.smegmatis_MC2_155 GGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGD
TH_3569|M.thermoresistible__bu ------------------------------PAPLLLAPGVSEAADAMATT
MAB_4284c|M.abscessus_ATCC_199 AAVAGNAAVGGVLNTGVSGAIGGSSHVGGAINESLGGSGSVGGSTAVGGG
Mb2377c|M.bovis_AF2122/97 GNLNTGFGSAGNGNVGIFDGGNSNSGSFNVGFQNTGFG-----NSGAGNT
Rv2356c|M.tuberculosis_H37Rv GNLNTGFGSAGNGNVGIFDGGNSNSGSFNVGFQNTGFG-----NSGAGNT
MMAR_3666|M.marinum_M GSSNTGFGSAGDGNFGLFNAGNHNSGSFNVGTESTGFG-----NSGAGNT
MUL_0964|M.ulcerans_Agy99 GGTNTGFGNGGSLNFGFGNGGVENMGHGNAGSFNMGFG-----NGGGGNT
MAV_4704|M.avium_104 GAVARGYTSR--------------------------------------IA
MLBr_01182|M.leprae_Br4923 ATVVPQVDQQVNVDVATPQTAVPDSSSAAAPQLWGGFA-----QHLSPIN
Mflv_5091|M.gilvum_PYR-GCK GGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGKA
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGTA
MSMEG_0868|M.smegmatis_MC2_155 GVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTL
TH_3569|M.thermoresistible__bu QQIGSQATAADSGTALNLSDLIANLLQYYQDYLDQLFG---------PIV
MAB_4284c|M.abscessus_ATCC_199 AHTGVGGGVSTGVGVGSHVGGGISESLGGSGSVGGSTAVG--GGAHTGVG
Mb2377c|M.bovis_AF2122/97 GFFNAGDSNTGFANAGNVNTGFFNG------GDINTGGFNGGNVNTGFGS
Rv2356c|M.tuberculosis_H37Rv GFFNAGDSNTGFANAGNVNTGFFNG------GDINTGGFNGGNVNTGFGS
MMAR_3666|M.marinum_M GFMNAGNSNTGAFNGGNVNTGFFNG------GNTNTGAFNGGDLNTAIGS
MUL_0964|M.ulcerans_Agy99 GFYNSGTYNTGFSNAAETNTGWENS------GNVNTGGYNSGGLNTGIGS
MAV_4704|M.avium_104 GFLAPRAPQ-----------------------------------------
MLBr_01182|M.leprae_Br4923 DTLSMINNHAGMANAGLSLVNGMGS------AMKSLAPTTTKAAESAFKA
Mflv_5091|M.gilvum_PYR-GCK GATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGATG
Mvan_1264|M.vanbaalenii_PYR-1 GVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGSAG
MSMEG_0868|M.smegmatis_MC2_155 GGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGG
TH_3569|M.thermoresistible__bu DFLRDPIGNLFQLIDDFLTN-------------------PAGALVTWWPL
MAB_4284c|M.abscessus_ATCC_199 GGVSTGVGVGSHVGGGISESLGGSG------SVGGSTAVGGGAHTGVGGG
.
Mb2377c|M.bovis_AF2122/97 ALTQAGANSGFG------------NLGTGNSGWGNSDP--SGTGNSGFFN
Rv2356c|M.tuberculosis_H37Rv ALTQAGANSGFG------------NLGTGNSGWGNSDP--SGTGNSGFFN
MMAR_3666|M.marinum_M SVSQSGLNSGFG------------NLGSGNSGFYNSDP--NGSANSGFFN
MUL_0964|M.ulcerans_Agy99 PDTQAGPNSGFG------------HSGSGNSGFFNSGDGNSGFENSNTCV
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 MG-SAVQSTGRG------------LLGSSSGGHVTAQLGRAASIGSLRVP
Mflv_5091|M.gilvum_PYR-GCK AAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA
Mvan_1264|M.vanbaalenii_PYR-1 SAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA
MSMEG_0868|M.smegmatis_MC2_155 AATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWV
TH_3569|M.thermoresistible__bu LFAVAYQVFTN-------------LVGWPTWAMILASPVLIPLAITLGVA
MAB_4284c|M.abscessus_ATCC_199 VNTGVGVGSHVGG---------GISESLGGSGSVGGSTAVGGGAHTSAIN
Mb2377c|M.bovis_AF2122/97 TGNGNSGFSNAGPAMLPGFNSGFANIGSFNAGIANSGNNLAGIS------
Rv2356c|M.tuberculosis_H37Rv TGNGNSGFSNAGPAMLPGFNSGFANIGSFNAGIANSGNNLAGIS------
MMAR_3666|M.marinum_M TGIGNSGVSNAGPALVPGYNSGFGNIGTNNAGFVNSGNRLAGIS------
MUL_0964|M.ulcerans_Agy99 SANGHSGVRNSG----DATNVGFSNSGSNNTGIFNTGTFNTGIA------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 QTWTTASQPVTAATRALSPARVAVATESESAPLLGGGLPMAPMV------
Mflv_5091|M.gilvum_PYR-GCK GATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG-------
Mvan_1264|M.vanbaalenii_PYR-1 GATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG-------
MSMEG_0868|M.smegmatis_MC2_155 QAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKS
TH_3569|M.thermoresistible__bu GLVMIADQAQPPAEEAAPEEDVAAPVRAEPQNPLPLTXXX----------
MAB_4284c|M.abscessus_ATCC_199 DALGGSGSVGGSTAVGGGAHTSAINESMNSSINASHSSSMNESFG-----
Mb2377c|M.bovis_AF2122/97 ---------------------------------NSGDDSSGAVNSGSQNS
Rv2356c|M.tuberculosis_H37Rv ---------------------------------NSGDDSSGAVNSGSQNS
MMAR_3666|M.marinum_M ---------------------------------NSGDDSSGFLNSGDQNS
MUL_0964|M.ulcerans_Agy99 ---------------------------------NSGSDSSGLLISGTNSS
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 ---------------------------------PGGGSGTGGVNTALRLQ
Mflv_5091|M.gilvum_PYR-GCK ----AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG-
Mvan_1264|M.vanbaalenii_PYR-1 ----AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG-
MSMEG_0868|M.smegmatis_MC2_155 GGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGN
TH_3569|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------SSMGSHGAAGTGFEAQ
Mb2377c|M.bovis_AF2122/97 GAFNAGVGLSGFFR-------------
Rv2356c|M.tuberculosis_H37Rv GAFNAGVGLSGFFR-------------
MMAR_3666|M.marinum_M GGFNSGTGLSGFFR-------------
MUL_0964|M.ulcerans_Agy99 GALNSGDDQSGFNN-------------
MAV_4704|M.avium_104 ---------------------------
MLBr_01182|M.leprae_Br4923 PRAFVMPRNPAAG--------------
Mflv_5091|M.gilvum_PYR-GCK -GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 -GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGGNGGADGTPGTAGTTGANNP
TH_3569|M.thermoresistible__bu ---------------------------
MAB_4284c|M.abscessus_ATCC_199 GHAQGHASETAHTTLPGAEHH------