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NYSVLPPEINSLRMFTGAGSAPMLAASVAWDRLAAELAVAASSFGSVTSGLAGQSWQGAAAAAMAAAAAP YAGWLAAAAARAAGASAQAKAVASAFEAARAATVHPMLVAANRNAFVQLVLSNLFGQNAPAIAAAEAMYE QMWAADVAAMVGYHGGASAAAAQLSSWSIGLQQALPAAPSALAAAIGLGNIGVGNLGGGNTGDYNLGSGN SGNANVGSGNSGNANVGSGNDGATNLGSGNIGNTNLGSGNVGNVNLGSGNRGFGNLGNGNFGSGNLGSGN TGSTNFGGGNLGSFNLGSGNIGSSNIGFGNNGDNNLGLGNNGNNNIGFGLTGDNLVGIGALNSGIGNLGF GNSGNNNIGFFNSGNNNVGFFNSGNNNFGFGNAGDINTGFGNAGDTNTGFGNAGFFNMGIGNAGNEDMGV GNGGSFNVGVGNAGNQSVGFGNAGTLNVGFANAGSINTGFANSGSINTGGFDSGDRNTGFGSSVDQSVSS SGFGNTGMNSSGFFNTGNVSAGYGNNGDVQSGINNTNSGGFNVGFYNSGAGTVGIANSGLQTTGIANSGT LNTGVANTGDHSSGGFNQGSDQSGFFGQP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3159c | PPE53 | - | 100% (590) | PPE FAMILY PROTEIN |
| M. tuberculosis H37Rv | Rv1135c | PPE16 | 0.0 | 64.02% (617) | PPE family protein |
| M. tuberculosis H37Rv | Rv2356c | PPE40 | 0.0 | 62.64% (613) | PPE family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3183c | PPE53 | 0.0 | 99.66% (590) | PPE family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 3e-25 | 30.67% (450) | triple helix repeat-containing collagen |
| M. leprae Br4923 | MLBr_01182 | - | 7e-30 | 37.82% (193) | PPE-family protein |
| M. abscessus ATCC 19977 | MAB_4284c | - | 5e-25 | 33.56% (435) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_1139 | - | 0.0 | 64.43% (610) | PPE family protein |
| M. avium 104 | MAV_4704 | - | 2e-49 | 53.33% (195) | PPE family protein |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 2e-25 | 29.79% (423) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3113 | - | 2e-24 | 40.51% (158) | PUTATIVE PPE protein |
| M. ulcerans Agy99 | MUL_0902 | - | 0.0 | 63.61% (610) | PPE family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 5e-27 | 26.09% (663) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3159c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3183c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1139|M.marinum_M --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Rv3159c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3183c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1139|M.marinum_M --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Rv3159c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3183c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1139|M.marinum_M --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Rv3159c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3183c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1139|M.marinum_M --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Rv3159c|M.tuberculosis_H37Rv -----------------------------------MN---YSVLPPEINS
Mb3183c|M.bovis_AF2122/97 -----------------------------------MN---YSVLPPEINS
MMAR_1139|M.marinum_M -----------------------------------MN---FPMLPPEINS
MUL_0902|M.ulcerans_Agy99 -----------------------------------MN---FPMLPPEINS
MAV_4704|M.avium_104 -----------------------------------MTNPHFAWLPPEVNS
MLBr_01182|M.leprae_Br4923 -------------------------------------MFDFAALSPETNS
TH_3113|M.thermoresistible__bu -----------------------------------------MALPPEVHS
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
MAB_4284c|M.abscessus_ATCC_199 --------------------------MSIIDFILNLFRDPVEAASYVADP
Rv3159c|M.tuberculosis_H37Rv LRMFTGAGSAPMLAASV-AWDRLAAELAVAASSFGSVTSGLAGQSWQGAA
Mb3183c|M.bovis_AF2122/97 LRMFTGAGSAPMLAASV-AWDRLAAELAVAASSFGSVTSGLAGQSWQG-A
MMAR_1139|M.marinum_M ARMFAGAGSGPMLSAAM-AWDGLAVELGSAAESFGSVTSGLVGSSWQGAA
MUL_0902|M.ulcerans_Agy99 ARMFAGAGSGPMLSAAM-AWDGLAVELGSAAESFGSVTSGLVGSSWQGAA
MAV_4704|M.avium_104 ALIYSGPGPGPLLAAAA-AWDGLAEELASSAQSFSSVTSDLASGSWQGAS
MLBr_01182|M.leprae_Br4923 TRMYLGPGSSPILTAAA-AWVVLAKELTAAAQGLQSAV-EALLTTFEGES
TH_3113|M.thermoresistible__bu TLLRTGPGPGALSAAAD-AWRMLSDEYRAAAVELAAVVSQTCATAWEGVG
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGS-GWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGS-GWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLG
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGH-GYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWA
MAB_4284c|M.abscessus_ATCC_199 EAALANAGLSAVSAAQVGAVMPVVAESVASNYGYQSQWVNTGNPIHDLSG
* . . . . . .
Rv3159c|M.tuberculosis_H37Rv AAAMAAAAAPYAGWLAAAAARAAGASAQAKAVASAFEAARAATVHPMLVA
Mb3183c|M.bovis_AF2122/97 AAAMAAAAAPYAGWLAAAAARAAGASAQAKAVASAFEAARAATVHPMLVA
MMAR_1139|M.marinum_M AAAMSAAAAPYVSWLNAAAVRAGEAALQAKEVVSAFEAARAAMIHPLAVA
MUL_0902|M.ulcerans_Agy99 ATAMSAAAAPYVSWLNAAAVRAGEAALQAKEVVSAFEAARAAMIHPLAVA
MAV_4704|M.avium_104 SAAMMTVANQYVSWLSAAAAQAEEVSHQASAIATAFEVALAATVQPAVVA
MLBr_01182|M.leprae_Br4923 AAALAERVTPYEKWLTQNAASAELTATQLTVAANAYETAFTMTVPPLMVF
TH_3113|M.thermoresistible__bu ADAYAAAHGPYLFWLTDTAAAAAAAGAQLEAAAAAHASALAAMPTMAELT
Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGAT
Mvan_1264|M.vanbaalenii_PYR-1 SGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGAT
MSMEG_0868|M.smegmatis_MC2_155 GLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGT
MAB_4284c|M.abscessus_ATCC_199 NLQNYYAAQPDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMS
: . .
Rv3159c|M.tuberculosis_H37Rv ANRNAFVQLVLSNLFGQNAPAIAAAEAMYEQMWAAD-------------V
Mb3183c|M.bovis_AF2122/97 ANRNAFVQLVLSNLFGQNAPAIAAAEAMYEQMWAAD-------------V
MMAR_1139|M.marinum_M ANRNALVQLVLTNLFGQNAPAIAAAEGSYEQMWAAD-------------V
MUL_0902|M.ulcerans_Agy99 ANRNALVQLVLTNLFGQNAPAIAAAEGSYEQMWAAD-------------V
MAV_4704|M.avium_104 ANRALVQALAATNWLGQNTPAIADIEAAYEQMWASD-------------V
MLBr_01182|M.leprae_Br4923 VNRAQACLLIMSNIFGQNSTAIAEKEAEYTEMWIQD-------------A
TH_3113|M.thermoresistible__bu ANRTTHAALVATNFFGVNTIPIAVNEADYARMWIQA-------------A
Mflv_5091|M.gilvum_PYR-GCK GVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------
Mvan_1264|M.vanbaalenii_PYR-1 GVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------
MSMEG_0868|M.smegmatis_MC2_155 GGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNV
MAB_4284c|M.abscessus_ATCC_199 P-SGNVDSFNRGPLLDLSFGDLQFGNRDTTAIGDGA-------------V
.
Rv3159c|M.tuberculosis_H37Rv AAMVGYHGGASAAAAQLSSWSIGLQQALPAAPSALAAAIGLGNIGVGNLG
Mb3183c|M.bovis_AF2122/97 AAMVGYHGGASAAAAQLSSWSIGLQQALPAAPSALAAAIGLGNIGVGNLG
MMAR_1139|M.marinum_M AAMLGYHGGASAAASGLASWQQALQG-LAGPAASVIPGLSIGNIGVGNLS
MUL_0902|M.ulcerans_Agy99 AAMLGYHGGASAAASGLASWQQALQG-LAGPAASVILGLSIGNTGVGNLS
MAV_4704|M.avium_104 AAMFGYHADASAAVAKLPPWNEVLQN------------------------
MLBr_01182|M.leprae_Br4923 AAMTSYQASVLEAVGATKAFTAPP-----------------LGVN-----
TH_3113|M.thermoresistible__bu TTMATYEAVASAAVSATPRTVAPPPI---------------LGAGTGESA
Mflv_5091|M.gilvum_PYR-GCK AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG-----
Mvan_1264|M.vanbaalenii_PYR-1 AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG-----
MSMEG_0868|M.smegmatis_MC2_155 TVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDG
MAB_4284c|M.abscessus_ATCC_199 AVGGSNSGPIASGQGSTAVNGDVRDSNIINADHGSNVGVDQSQTRVGGDY
:. . .
Rv3159c|M.tuberculosis_H37Rv GGNTGDYNLGSGNSGNANVGSGNS---------GNANVGSGNDGATNLGS
Mb3183c|M.bovis_AF2122/97 GGNTGEYNLGSGNSGNANVGSGNS---------GNANVGSGNDGATNLGS
MMAR_1139|M.marinum_M IGNIGDFNLGGGNAGNLNLGGGNT---------GNANLGSGNNGFFNLGS
MUL_0902|M.ulcerans_Agy99 IGNIGVFNLGGGNAGNLNLGGGNT---------GNANLGSGNNGFFNLGS
MAV_4704|M.avium_104 --------LGFSNASTAVTRPAGS---------GAVARG-----------
MLBr_01182|M.leprae_Br4923 ---------EVGLAQEVVEEVVEE---------VVEEVVEAEQAISQAAL
TH_3113|M.thermoresistible__bu TAAITGAHVTAELRAAESRTLLDE---------INELIDRLFAPLFPPGF
Mflv_5091|M.gilvum_PYR-GCK --AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAAGGAGGL
Mvan_1264|M.vanbaalenii_PYR-1 --VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAAGQAGTA
MSMEG_0868|M.smegmatis_MC2_155 HAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGH
MAB_4284c|M.abscessus_ATCC_199 TNVSGHGSADIDKSVTVVDDHSQR---------NTTNINDSFNTDRSTNI
Rv3159c|M.tuberculosis_H37Rv GNIGNTNLGSGNV-------------------------------------
Mb3183c|M.bovis_AF2122/97 GNIGNTNLGSGNV-------------------------------------
MMAR_1139|M.marinum_M GNTGNTNFGNGNR-------------------------------------
MUL_0902|M.ulcerans_Agy99 GNTGNTNFGNGNR-------------------------------------
MAV_4704|M.avium_104 -------YTSRIA-------------------------------------
MLBr_01182|M.leprae_Br4923 DQAVNEGMEATVV-------------------------------------
TH_3113|M.thermoresistible__bu ADALPDGLLGTLL-------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GETGTTGGAGGVG--------------------GQGTAGGTGGVGGIGGA
Mvan_1264|M.vanbaalenii_PYR-1 GETGVTGGVGGIG--------------------GQGTEGGTGGVGGVGGV
MSMEG_0868|M.smegmatis_MC2_155 STGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEI
MAB_4284c|M.abscessus_ATCC_199 GSGNTTNTEIGSHN------------------------------------
Rv3159c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3183c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1139|M.marinum_M --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK G----------STGAVGG-------VGGKG----IQGGQG----------
Mvan_1264|M.vanbaalenii_PYR-1 G----------ATGGAGG-------VGGKG----IQGGQG----------
MSMEG_0868|M.smegmatis_MC2_155 YSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGT
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Rv3159c|M.tuberculosis_H37Rv ---GNVNLGSGNR-----GFGN-LGNGNFGSG------NLGSGNTGSTNF
Mb3183c|M.bovis_AF2122/97 ---GNVNLGSGNR-----GFGN-LGNGNFGSG------NLGSGNTGSTNF
MMAR_1139|M.marinum_M ---GNLNWGSGNLGNANVGFGNFLGQGNFGFGNRVGDANLGSGNLGNANF
MUL_0902|M.ulcerans_Agy99 ---GNLNWGSGNLGNANVGFGNFLGQGNFGFGNRVGDANLGSGNLGNANF
MAV_4704|M.avium_104 ---GFLAPRAPQ--------------------------------------
MLBr_01182|M.leprae_Br4923 ---PQVDQQVN---------------------------------------
TH_3113|M.thermoresistible__bu ---APLLPGATGD-------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ---LQGGKGGDGGAGGKGGDADSMGS------------------AGATGG
Mvan_1264|M.vanbaalenii_PYR-1 ---LQGGQGGDGGTGGTGGDATSMGE------------------AGATGG
MSMEG_0868|M.smegmatis_MC2_155 AKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGA
MAB_4284c|M.abscessus_ATCC_199 --QANIGTSTSAG---------------------------------GSAA
Rv3159c|M.tuberculosis_H37Rv GGGNLGSFNLGSGNI-----------------------------------
Mb3183c|M.bovis_AF2122/97 GGGNLGSFNLGSGNI-----------------------------------
MMAR_1139|M.marinum_M GNGNLGDTNLGSGNN-----------------------------------
MUL_0902|M.ulcerans_Agy99 GNGNLGDTNLGSGNN-----------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --GPPMATIMSFLLM-----------------------------------
Mflv_5091|M.gilvum_PYR-GCK KGGNGGNGGRGGLFG---------------KGGNAGNGAD----------
Mvan_1264|M.vanbaalenii_PYR-1 KGGNGGNGGRGSLFG---------------RGGNAGNGGN----------
MSMEG_0868|M.smegmatis_MC2_155 VGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNG
MAB_4284c|M.abscessus_ATCC_199 VGGNAGLAGNAGLAG-----------------------------------
Rv3159c|M.tuberculosis_H37Rv --------------GSSNIGFGNNGDNNLGLGNNGN--------------
Mb3183c|M.bovis_AF2122/97 --------------GSSNIGFGNNGDNNLGLGNNGN--------------
MMAR_1139|M.marinum_M --------------GFSNVGFGNLGSNNLGFGNNGD--------------
MUL_0902|M.ulcerans_Agy99 --------------GFSNVGFGNLGSNNLGFGNNGD--------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 -------------------------------VDVAT--------------
TH_3113|M.thermoresistible__bu --------------GLSNPAYLFPVLVYLLFTGVVH--------------
Mflv_5091|M.gilvum_PYR-GCK ------------GGTGGAGGAGGTGG-TGGAGGTGG--------------
Mvan_1264|M.vanbaalenii_PYR-1 ------------GGTGGNGGNGGTGG-TGGNGGTGG--------------
MSMEG_0868|M.smegmatis_MC2_155 PAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTG
MAB_4284c|M.abscessus_ATCC_199 -----------------NAGLAGNAGLAGNAGLAGN--------------
Rv3159c|M.tuberculosis_H37Rv -------NNIGFGLTGDNLVGIG--ALNSGIGNLGFGNSGNNNIGFFNSG
Mb3183c|M.bovis_AF2122/97 -------NNIGFGLTGDNLVGIG--ALNSGIGNLGFGNSGNNNIGFFNSG
MMAR_1139|M.marinum_M -------NNIGFGLTGNNQVGINFAGLNGGIGNIGLGNSGDNNVGFFNSG
MUL_0902|M.ulcerans_Agy99 -------NNIGFGLTGNNQVGINFAGLNGGIGNIDLGNSGDNNVGFFNSG
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 -------PQTAVPDSSSAAAPQLWGGFAQHLSPIN------DTLSMINN-
TH_3113|M.thermoresistible__bu -------TTVAVSGMLAQLVPLMPALLPVAVAALGGLAGVWAGLSGLAG-
Mflv_5091|M.gilvum_PYR-GCK ---TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGK
Mvan_1264|M.vanbaalenii_PYR-1 ---TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGK
MSMEG_0868|M.smegmatis_MC2_155 QTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGR
MAB_4284c|M.abscessus_ATCC_199 -------AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNA
Rv3159c|M.tuberculosis_H37Rv NNNVGFFNSGNNNFGFGNAGDINTGFGNAGDT--------NTGFGNAGFF
Mb3183c|M.bovis_AF2122/97 NNNVGFFNSGNNNFGFGNAGDINTGFGNAGDT--------NTGFGNAGFF
MMAR_1139|M.marinum_M SNNVGFFNSGDGNFGFANAGDTNTGFWNAGRV--------NTGFGNGGNF
MUL_0902|M.ulcerans_Agy99 SNNVGFFNSGDRNFGFANSGDTNTGFWNAGRV--------NTGFGNGGNF
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 -------HAGMANAGLSLVNGMGSAMKSLAPT--------TTKAAESAFK
TH_3113|M.thermoresistible__bu -------LAGLTAVPAADGGASAAPVPAGGPS--------LPSGSSAPPA
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 GGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNG
MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAG--LAGNAGLAGNAGLAGNAG--------LAGNAGLAG
Rv3159c|M.tuberculosis_H37Rv NMG--------------IGNAGNED-------------------------
Mb3183c|M.bovis_AF2122/97 NMG--------------IGNAGNED-------------------------
MMAR_1139|M.marinum_M NLG--------------FGNGGAAN-------------------------
MUL_0902|M.ulcerans_Agy99 NLG--------------FGNGGAAN-------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 AMG--------------SAVQSTGR-------------------------
TH_3113|M.thermoresistible__bu PTG--------------SAAPTTGT-------------------------
Mflv_5091|M.gilvum_PYR-GCK GAG-----------DGTGGTGGTGG----TGGQGGQGGQGG---------
Mvan_1264|M.vanbaalenii_PYR-1 GAG-----------DGLGGTGGTGG----TGGFGGQGGQGG---------
MSMEG_0868|M.smegmatis_MC2_155 GAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVI
MAB_4284c|M.abscessus_ATCC_199 NAG-------------LAGNAGLAG-------------------------
Rv3159c|M.tuberculosis_H37Rv -------------------------------------------------M
Mb3183c|M.bovis_AF2122/97 -------------------------------------------------M
MMAR_1139|M.marinum_M -------------------------------------------------V
MUL_0902|M.ulcerans_Agy99 -------------------------------------------------V
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 -------------------------------------------------G
TH_3113|M.thermoresistible__bu -------------------------------------------------A
Mflv_5091|M.gilvum_PYR-GCK --------TGGTGGQGG-LGGGGGTG-----------------------G
Mvan_1264|M.vanbaalenii_PYR-1 --------TGGTGGQGG-LGGVGGTG-----------------------G
MSMEG_0868|M.smegmatis_MC2_155 GSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDG
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Rv3159c|M.tuberculosis_H37Rv GVGNGGSFNVGVGNAGNQSVGFGNAG------TLNVGFANAGSINTGFAN
Mb3183c|M.bovis_AF2122/97 GVGNGGSFNVGVGNAGNQSVGFGNAG------TLNVGFANAGSINTGFAN
MMAR_1139|M.marinum_M GVGNGGGGNMGFGNSGTENTGSFNSGGDNGPNGGNTGSFNSGYVNTGFFN
MUL_0902|M.ulcerans_Agy99 GVGNGGGGNLGFGNSGTENTGSFNSGGDNGRNGGNTGSFNSGYVNTGFFN
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 LLGSSS----GGHVTAQLGR------------AASIGSLRVPQTWTTASQ
TH_3113|M.thermoresistible__bu PGGAGSPPPAGHSVPPAPHS------------APPVGTSGPPYLIAAQPA
Mflv_5091|M.gilvum_PYR-GCK QGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGG
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGG
MSMEG_0868|M.smegmatis_MC2_155 HGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGG
MAB_4284c|M.abscessus_ATCC_199 NAAVAGNAAVAGNAAVAGNAAVGGVLNTGVSGAIGGSSHVGGAINESLGG
Rv3159c|M.tuberculosis_H37Rv SGSINTGGFDSGDRNTGFGSSVDQSVSSSGFGNTG---------------
Mb3183c|M.bovis_AF2122/97 SGSINTGGFDSGDRNTGFGSSVDQSVSSSGFGNTG---------------
MMAR_1139|M.marinum_M SGSTNTGLFNAGSVNTGIGSPDTQPGSISGFGNTG---------------
MUL_0902|M.ulcerans_Agy99 SGSTNTGLFNAGSVNTGIGSPDTQPGSISGFGNTG---------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 PVTAAT------RALSPARVAVATESESAPLLGGG---------------
TH_3113|M.thermoresistible__bu PGVARR------SAGARRAASIVEPAGSAAAAAAA---------------
Mflv_5091|M.gilvum_PYR-GCK SGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGK
Mvan_1264|M.vanbaalenii_PYR-1 VGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGT
MSMEG_0868|M.smegmatis_MC2_155 DGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGST
MAB_4284c|M.abscessus_ATCC_199 SGSVGGSTAVGGGAHTGVGGGVSTGVGVGSHVGGG---------------
Rv3159c|M.tuberculosis_H37Rv ---MNSSGFFNTGNVSAGYGNNGD---VQSGINNTNSGGFNVGFYNSGAG
Mb3183c|M.bovis_AF2122/97 ---MNSSGFFNTGNVSAGYGNNGD---VQSGINNTNSGGFNVGFYNSGAG
MMAR_1139|M.marinum_M ---AGVSGFNNSGDATSGFMNVATTFGFTSGIN--NVGDYQVGLFNTGFG
MUL_0902|M.ulcerans_Agy99 ---AGVSGFNNSGDATSGFMNVATTFGFASGIN--NVGDYQVGLFNTGFG
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 ---LPMAPMVPGGG--------------------------------SGTG
TH_3113|M.thermoresistible__bu ---RESAPIRRRRGQKDGLHGHRHEHQQPASMSAATAPSAAGIRVLGGAG
Mflv_5091|M.gilvum_PYR-GCK AGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGAT
Mvan_1264|M.vanbaalenii_PYR-1 AGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGSA
MSMEG_0868|M.smegmatis_MC2_155 LGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDG
MAB_4284c|M.abscessus_ATCC_199 --ISESLGGSGSVGGSTAVGGGAHTGVGGGVSTGVGVGSHVGGGISESLG
Rv3159c|M.tuberculosis_H37Rv TVGIANSGLQTTG---------------IANSGTLNTGVANTGDHSSGGF
Mb3183c|M.bovis_AF2122/97 TVGIANSGLQTTG---------------IANSGTLNTGVANTGDHSSGGF
MMAR_1139|M.marinum_M NAGIANSGNATFG---------------IANSGALSSGISNSGTNSSGGF
MUL_0902|M.ulcerans_Agy99 NAGIANSGNATFG---------------IANSGALSSGISNSGTNSSGGF
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 GVNTALRLQPRAF---------------VMPRNPAAG-------------
TH_3113|M.thermoresistible__bu RISRTRGSVPHAE---------------ITPGDPTEPSSPTDRAHRPAEP
Mflv_5091|M.gilvum_PYR-GCK GAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGK
Mvan_1264|M.vanbaalenii_PYR-1 GSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGK
MSMEG_0868|M.smegmatis_MC2_155 GAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGW
MAB_4284c|M.abscessus_ATCC_199 GSGSVGGSTAVGG-------------GAHTGVGGGVNTGVGVGSHVGGGI
Rv3159c|M.tuberculosis_H37Rv NQGSDQSGFFGQP-------------------------------------
Mb3183c|M.bovis_AF2122/97 NQGSDQSGFFGQP-------------------------------------
MMAR_1139|M.marinum_M NTGDDQSGFFN---------------------------------------
MUL_0902|M.ulcerans_Agy99 NTGDDQSGFFN---------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu N-------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG------
Mvan_1264|M.vanbaalenii_PYR-1 AGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG------
MSMEG_0868|M.smegmatis_MC2_155 VQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWK
MAB_4284c|M.abscessus_ATCC_199 SESLGGSGSVGG-------STAVGGGAHTSAINDALGGSGSVGG------
Rv3159c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3183c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1139|M.marinum_M --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -----AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG
Mvan_1264|M.vanbaalenii_PYR-1 -----AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG
MSMEG_0868|M.smegmatis_MC2_155 SGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSG
MAB_4284c|M.abscessus_ATCC_199 ----STAVGGGAHTSAINESMNSSINASHSSSMNESFGSSMGSHGAAGTG
Rv3159c|M.tuberculosis_H37Rv ----------------------------
Mb3183c|M.bovis_AF2122/97 ----------------------------
MMAR_1139|M.marinum_M ----------------------------
MUL_0902|M.ulcerans_Agy99 ----------------------------
MAV_4704|M.avium_104 ----------------------------
MLBr_01182|M.leprae_Br4923 ----------------------------
TH_3113|M.thermoresistible__bu ----------------------------
Mflv_5091|M.gilvum_PYR-GCK --GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 --GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 NGGNGGNGGNGGADGTPGTAGTTGANNP
MAB_4284c|M.abscessus_ATCC_199 FEAQGHAQGHASETAHTTLPGAEHH---