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M. tuberculosis H37Rv Rv1557 (mmpL6)

annotation: PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL6
coordinates: 1761744 - 1762937
length: 397

VQGISVTGLVKRGWMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALA
NYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAARMIISHEG
DPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLLIAGIAALSLILLIMMII
TRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGA
GLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLG
RWFWWPQRVRPRPASRMLRPYGPRPVVRELLLREGNDDPRTQVATHR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1557mmpL6-100% (397)PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL6
M. tuberculosis H37RvRv0507mmpL2e-14868.78% (378) transmembrane transport protein MmpL2
M. tuberculosis H37RvRv0450cmmpL4e-13463.96% (369) transmembrane transport protein MmpL4

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1583mmpL60.099.48% (384) transmembrane transport protein MmpL6
M. gilvum PYR-GCKMflv_4418-1e-13564.09% (362) transport protein
M. leprae Br4923MLBr_02378-1e-13063.26% (362) hypothetical protein MLBr_02378
M. abscessus ATCC 19977MAB_0987c-1e-14470.56% (360) membrane protein MmpL
M. marinum MMMAR_0775-1e-15067.65% (374) MmpL family transport protein
M. avium 104MAV_3863-1e-15876.28% (371) MmpL4 protein
M. smegmatis MC2 155MSMEG_0382-1e-14867.93% (368) putative transport protein
M. thermoresistible (build 8)TH_3056-1e-14164.42% (371) PUTATIVE Mmp14a protein
M. ulcerans Agy99MUL_0757mmpL51e-13362.43% (362) transmembrane transport protein, MmpL5
M. vanbaalenii PYR-1Mvan_1936-1e-13365.16% (353) transport protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4418|M.gilvum_PYR-GCK          ---------------------------------MADAGRSGIGRIIRVLA
Mvan_1936|M.vanbaalenii_PYR-1       ---------------------------------MADAGRSGIGRIIHLLA
MUL_0757|M.ulcerans_Agy99           ------------------MTATTTDTPTDVVPPAEHPPRPFIPRMIRTFA
MMAR_0775|M.marinum_M               MSDDQAVSERAASNGASNGAGAENGNGNENGNGNGNGSRPSMARLIHRMA
MSMEG_0382|M.smegmatis_MC2_155      --------------------------MSTEQSGTEKARRPFFARAVRTLS
TH_3056|M.thermoresistible__bu      --------------------------MSVLDRVGVEPRRPRVASFIRRYS
MLBr_02378|M.leprae_Br4923          ------------------------MTVKCANDLDTHTKPPFVARMIHRFA
Rv1557|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1583|M.bovis_AF2122/97            -------------------------------MSNHHRPRPWLPHTIRRLS
MAV_3863|M.avium_104                -------------------------------MTTDQATRSVVAQTIRRLS
MAB_0987c|M.abscessus_ATCC_199      -------------------------------MSANHAHESRAAKIVRRLA
                                                                                      

Mflv_4418|M.gilvum_PYR-GCK          VPIVLGWVLLTVLTN---------VAVPSLEKVGEEHTVGMSAGDAPSMM
Mvan_1936|M.vanbaalenii_PYR-1       VPIVLGWIALTVLTN---------VAVPSLEKVGEEHTVGMSANDAPSMM
MUL_0757|M.ulcerans_Agy99           VPLILGWVLLIAVLN---------SVVPQLEVVGQMQAVSMSPDAAPSMI
MMAR_0775|M.marinum_M               VPIVVFWVGLVAVLV---------MFVPSLEEVGKQHTVSLSPSDAESMI
MSMEG_0382|M.smegmatis_MC2_155      PFIIVGWLAVILVTTLAAVGGDWSAAIPALERVGEKNSVSLMPQDAPSAK
TH_3056|M.thermoresistible__bu      VLIILGWVALTVLAT---------VAVPPLEAVEREKSLSLIPYDAPAFA
MLBr_02378|M.leprae_Br4923          VPIILVWLAIAVTVS---------VFIPSLEDVGQERSVSLSPKDAPSYI
Rv1557|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1583|M.bovis_AF2122/97            LPILLFWVGVAAITN---------AAVPQLEVVGEAHNVAQSSPDDPSLQ
MAV_3863|M.avium_104                VPILLVWVAVAAISN---------IAVPNLEDVAKAHNVSLNTPAAPSFQ
MAB_0987c|M.abscessus_ATCC_199      VPIVLFWVAIAAVTN---------ATVPQLEVVGEERSAPLNAADAPSTL
                                                                                      

Mflv_4418|M.gilvum_PYR-GCK          SMKRVGANFEEFDSDSSAMVVLEGEQPLGDAAHRYYDQLIDELEADTANV
Mvan_1936|M.vanbaalenii_PYR-1       SMERVGANFDEFDSDSSAMVVLEGEQPLGDAAHRYYDELIGKLEADTANV
MUL_0757|M.ulcerans_Agy99           SMKHIGKVFREGDSDSAAMIVLEGQEPLGAAAHKFYDKMITKLRADTKHV
MMAR_0775|M.marinum_M               AMKRVGKVFNEFDTDSAVMIVLEGDHPLGDEAHHYYDELVRKLKADKDHV
MSMEG_0382|M.smegmatis_MC2_155      AMKHMGQKFEESDSDSFAMIVLEGQEPLGPDALDYYTGLISELRNDSKHV
TH_3056|M.thermoresistible__bu      AMHRMGELFDEPDSESIAIIVLEGQEPLGLEAHEYYDQLISQLREHPQYV
MLBr_02378|M.leprae_Br4923          AMQKMGQVFNEGNSDSVIMIVLEGDKPLGDDAHRFYDGLIRKLRAD-KHV
Rv1557|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1583|M.bovis_AF2122/97            AMKRIGKVFHEFDSDSAAMIVLEGDKPLGNDAHRFYDTLLRNLSNDTKHV
MAV_3863|M.avium_104                AMQHIGKVFHEYDSDSAAMIVLEGDKPLGDDAHRFYDALVGKLEHDTKHV
MAB_0987c|M.abscessus_ATCC_199      AMRHIGKVFNEFDSDSSAMVVLEGEKPLGAQAHQFYNTLVQRLNDDHEHV
                                                                                      

Mflv_4418|M.gilvum_PYR-GCK          QHIADFWGDPLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIV
Mvan_1936|M.vanbaalenii_PYR-1       QHVADFWGDPLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIV
MUL_0757|M.ulcerans_Agy99           QSVQDFWGDPLTATGAQSGDGKAAYVQVKLAGNQGESLANESVEAVKTIV
MMAR_0775|M.marinum_M               QHVQDFWGDPLTAAGSQSPDGKAAYVQAYLVGNQGEAKANESVDAVRELV
MSMEG_0382|M.smegmatis_MC2_155      EHVQDLWGDRLTASSAQSADGKAAYVQLNLAGNQGTPLGDESVAAVRDLV
TH_3056|M.thermoresistible__bu      QHIRDFWGDPLTAGAAQSDDGKAAFVQVNLVGRFGQAKVNEAVRAVQEIV
MLBr_02378|M.leprae_Br4923          QSVQDFWGDPLTAPGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIV
Rv1557|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1583|M.bovis_AF2122/97            EHVQDFWGDPLTAAGSQSTDGKAAYVQVYLAGNQGEALSIESVDAVRDIV
MAV_3863|M.avium_104                EHVQNFWGDPLTAAGSQSKDGKAAYVQVYLAGNQGDALANESVDAIRNIV
MAB_0987c|M.abscessus_ATCC_199      QHVADYWGDPITAGGSQSKDGKAAYVQVYVAGNQGEALSNESVDAVRRII
                                                                                      

Mflv_4418|M.gilvum_PYR-GCK          DRTPAPPGIKAYVTGGAPLVADQHSAGDTSVLRVTLITIGVIAVMLLIVF
Mvan_1936|M.vanbaalenii_PYR-1       DQTPAPPGLKAYVTGGAPLVADQHNAGDKSVFRVTLITIGVIAVMLLLVF
MUL_0757|M.ulcerans_Agy99           DSLQAPPGVKVYVTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVY
MMAR_0775|M.marinum_M               NDTPAPPGVKAYVTGPAALIADQSTAGDASIQRVTFITIGVIFVMLLSVY
MSMEG_0382|M.smegmatis_MC2_155      ARTPAPEGVSVYVTGAAPLVSDMQHSGNRSILKITAVTVVIIFAMLLMVY
TH_3056|M.thermoresistible__bu      ERTPAPEGVETFVTGPAALGADAGDSGTATVILITLVTVAVIFLMLLFFF
MLBr_02378|M.leprae_Br4923          VQTPAPPGITAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVY
Rv1557|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1583|M.bovis_AF2122/97            AHTPPPAGVKAYVTGAAPLMADQFQVGSKGTAKVTGITLVVIAVMLLFVY
MAV_3863|M.avium_104                EHTPPPPGVKAYVTGAAPLVTDQFEVGSKGIFKVTVITVLVILAMLLWVY
MAB_0987c|M.abscessus_ATCC_199      AETPAPDGIKAYVSGEAPTITDQFEVGNAGAAQVTIITFAVIAVMLLVVY
                                                                                      

Mflv_4418|M.gilvum_PYR-GCK          RSVATMVLILFMVFAELGAARGIVAFLADAEIIGLSTFATSLLTLMVIAA
Mvan_1936|M.vanbaalenii_PYR-1       RSVATMVLILFMVFAELGAARGIVAFLANAEIIGLSTFATSLLTLMVIAA
MUL_0757|M.ulcerans_Agy99           RSIITAAIMLTMVVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAA
MMAR_0775|M.marinum_M               RSLITVISVLVMVGIELMAARGVVAFLADNNVIGLSTFAVNLLVLMAIAA
MSMEG_0382|M.smegmatis_MC2_155      RSVITVILLLIMVGFEVAAARGIVAFLGANEVFVLSTFAVNMLVFLAIAA
TH_3056|M.thermoresistible__bu      RSFLTVIVLLLTVAVELQVARGLVAYLGLQGWVGLTTYVVNLLVSVGIAA
MLBr_02378|M.leprae_Br4923          RSFITVILLLFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAA
Rv1557|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1583|M.bovis_AF2122/97            RSVVTMVLVLITVLIELAAARGIVAFLGNAGVIGLSTYSTNLLTLLVIAA
MAV_3863|M.avium_104                RS-VTAVFVLVTVIVEMAAARGIVAFLGSVGLIGLSTYATNLLTLLVIAA
MAB_0987c|M.abscessus_ATCC_199      RSLITTALVLAMVMVELSAARGIVAALGHTGVIGLSTYATNLLTMLAIAA
                                                                                      

Mflv_4418|M.gilvum_PYR-GCK          GTDYAIFAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLC
Mvan_1936|M.vanbaalenii_PYR-1       GTDYAIFAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLC
MUL_0757|M.ulcerans_Agy99           ATDYAIFLIGRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFC
MMAR_0775|M.marinum_M               GTDYAIFVLGRYQEARGEGESREKAFYTMFHGTAHVVLGSGLTIAGAMYC
MSMEG_0382|M.smegmatis_MC2_155      GTDYGIFFFGRYQEARAAGEDRETAYYSMYRGVTPVVMASGLTIAGAIFC
TH_3056|M.thermoresistible__bu      GTDYGIFFFGRYQEAREAGEDRDSAYFTTYRSVAKVVLASGLTIAGAIAC
MLBr_02378|M.leprae_Br4923          GTDYGIFITGRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFC
Rv1557|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1583|M.bovis_AF2122/97            GTDYAIFVLGRYHEARYAAQDRETAFYTMYRGTAHVVLGSGLTVAGAVYC
MAV_3863|M.avium_104                GTDYAIFFVGRYHEARHEGQDRETAYYTMYRGTTHVVLGSGLTVAGAVLC
MAB_0987c|M.abscessus_ATCC_199      GTDYAIFFVGRYQEARSAGEDRPSAYQTMYKSTAHVIIGSGLTVAGALFC
                                                                                      

Mflv_4418|M.gilvum_PYR-GCK          LSFTRLPYFQTMGVPCAVGTFVAVIAALTLGPAVIVIGSRFG-LFDPKRA
Mvan_1936|M.vanbaalenii_PYR-1       LSFTRLPYFQTMGVPCAVGTFVAVMAALTLGPAVVAIGSRFG-LFDPKRA
MUL_0757|M.ulcerans_Agy99           LSFTRLPYFQTLGVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPKRM
MMAR_0775|M.marinum_M               LSFTRLPYFQTLGAPCAVGMLVAVLAALTLGPAVLVVGSFFK-LFDPKRK
MSMEG_0382|M.smegmatis_MC2_155      LTFTRLPYFHTMGVPCAIGMLAAVAVAVTLVPAGVALAGRIG-WLEPKRK
TH_3056|M.thermoresistible__bu      LSFTRLPHFQPLGIPGAVGLLVAVAVALTLVPATIALGSRFG-LFEPKRR
MLBr_02378|M.leprae_Br4923          LSFARMPYFQTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRL
Rv1557|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1583|M.bovis_AF2122/97            LSFTRLPYFQSLGIPASIGVMIALAAALSLAPSVLILGSRFG-CFEPKRR
MAV_3863|M.avium_104                LRFTRLNYFQSLGIPAAIGIGVALAAALSLTPAVITVGSLFG-LFDPKRQ
MAB_0987c|M.abscessus_ATCC_199      LSFTRLPYFQTLGVPAALGVLVTLAAALTLAPAVLVIAGRFG-LMEPKRA
                                                                                      

Mflv_4418|M.gilvum_PYR-GCK          ISSRGWRRIGVSVVRWPGPVLAATLALALVGLVTLPGYKTNYDARDYLPE
Mvan_1936|M.vanbaalenii_PYR-1       ISSRGWRRIGVSVVRWPGPVLAATLALALVGLVALPGYKTNYDSRDYLPE
MUL_0757|M.ulcerans_Agy99           ARVRGWRKIGAAIVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLPA
MMAR_0775|M.marinum_M               MRTRGWRRVGTAIVRWPGPILAVSIAIALIGLLALPGYRTNYDSKKYLPA
MSMEG_0382|M.smegmatis_MC2_155      MRVRRWRGIGTAIVRWPAPILVASLAVALVGLLALPGYETSYNDRDYIPA
TH_3056|M.thermoresistible__bu      VMTHRWRRIGTAVVRWPVPILTAAVALSLVGLLTLPGYNPSYSDQEFIPD
MLBr_02378|M.leprae_Br4923          IKVRGWRRIGTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPA
Rv1557|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1583|M.bovis_AF2122/97            MRTRGWRRIGTAIVRWPGPILAVACAIAVVGLLALPGYKTSYDARYYMPA
MAV_3863|M.avium_104                MATRGWRRIGTAIVRWPGPILVVATGVALVGLLALPGYRTNYDARPYMPA
MAB_0987c|M.abscessus_ATCC_199      MRTRGWRRIGTAIVRWPGPILVVSCIATLVGLLALPGYRTTYDGRIYMPS
                                                                                      

Mflv_4418|M.gilvum_PYR-GCK          DIPANVGYAVADQHFGSARMN-PELLMVESDHDLRNPADFLVIDKIAKSV
Mvan_1936|M.vanbaalenii_PYR-1       DVPANVGYAVADRHFGSARMN-PELLMVESDHDLRNPADFLVIDKIAKAI
MUL_0757|M.ulcerans_Agy99           DLPANEGYSAAERHFSQARMN-PEVLMVESDHDMRNSSDFLVINKIAKAI
MMAR_0775|M.marinum_M               STPTNVGYTAADRHFSQARMN-PELLMVETDHDMRNPADMLVIDRIAKGV
MSMEG_0382|M.smegmatis_MC2_155      DIPANAGFAAADRHFSQARMT-PDILMVESDHDMRNPTDFLVLNKIAKAI
TH_3056|M.thermoresistible__bu      DIPASEGYKAAARHFPASAMSVPDVVLIEADRDMRNPADLLVLNKVAKKI
MLBr_02378|M.leprae_Br4923          SIPANQGFAAADRHFPQARMK-PEILMIESDHDMRNPADFLILDKLARGI
Rv1557|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1583|M.bovis_AF2122/97            TAPANIGYMAAERHFPQARLN-PELLMIETDHDMRNPADMLILDRIAKAV
MAV_3863|M.avium_104                SAPANTGYTAAERHFSQARLN-PELLMIETDHDMRNPADMINLERVAKAI
MAB_0987c|M.abscessus_ATCC_199      SVPSNVGYAAAERHFSVARLN-PELLMIETDFDMRNPAGMVLLERVAKSV
                                                                                      

Mflv_4418|M.gilvum_PYR-GCK          FRVPGVARVQTITRPDGKPIKHTTIPFQMSMQGTTQRLNEKYLQDRMADM
Mvan_1936|M.vanbaalenii_PYR-1       FRVPGVARVQTITRPDGKPIKHTTIPFQMSMRSTTSRLNEKYMQDRMADM
MUL_0757|M.ulcerans_Agy99           FGVEGISRVQAITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSM
MMAR_0775|M.marinum_M               FHLPGVARVQAVTRPLGKPIEHSSIPFQISMQNTVQVENMQYMKQRMADM
MSMEG_0382|M.smegmatis_MC2_155      FKVRGVSRVQGITRPEGTPIERTSIPFLLSLQSAGQVQATNFQKQRIGDM
TH_3056|M.thermoresistible__bu      FEVPGVANVQSVTRPEGRQIEHTTIPFMLSMSQASQRLALPFQRARMDDM
MLBr_02378|M.leprae_Br4923          FRVPGISRVQAITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDL
Rv1557|M.tuberculosis_H37Rv         --MQGISVTGLVKR------------------------------------
Mb1583|M.bovis_AF2122/97            FHLPGIGLVQAMTRPLGTPIDHSSIPFQISMQSVGQIQNLKYQRDRAADL
MAV_3863|M.avium_104                AHLPGIAQVQSMTRPLGTPIEHTSLAFQISAGSIGSIENLQYQKERAEDL
MAB_0987c|M.abscessus_ATCC_199      LHARGVALVQSITRPLGTPITHSSIPFQISASSASQLMNLSQQQNQALYL
                                        *:. .  :.*                                    

Mflv_4418|M.gilvum_PYR-GCK          LVQADAMQTNVDTMTRMQSLMGQMSATTHEMVLKTKKTEIDIIEVRDNLA
Mvan_1936|M.vanbaalenii_PYR-1       LVQADAMQTNVDTMTKMQSLMTQMSAATHDMVTKTKKTAVDIVEVRDYLA
MUL_0757|M.ulcerans_Agy99           LQQVNDIQTNIDQMERMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIA
MMAR_0775|M.marinum_M               LIQAAAMQDSIDTLDRMYDIMGKMVETTHDMDGLTHDMVEITDELRDHIA
MSMEG_0382|M.smegmatis_MC2_155      LKQVDDMNMMIGVMKTTYGVLQELAATTHSLNGSTHELRDVARDLRGSIA
TH_3056|M.thermoresistible__bu      LKQADELTETIALMRRMQSLMEKMVATTHSMVGTTHELLDTTRDLRDHIA
MLBr_02378|M.leprae_Br4923          LRQAENMAETIASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIA
Rv1557|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1583|M.bovis_AF2122/97            LKQAEELGKTIEILQRQYALQQELAAATHEQAESFHQTIATVKELRDRIA
MAV_3863|M.avium_104                LKQADNLKDTIGILNQQYALQKQLAASTHDETQSFHDTIAIINDLRDKIA
MAB_0987c|M.abscessus_ATCC_199      SQQADQMTNTIAVLRQQLALQKQSAAITHEQTEGFQQTVAVAQDLRDKIA
                                                                                      

Mflv_4418|M.gilvum_PYR-GCK          DFDDFFRPVRNYFYWEPHCYDIPVCWTMRSVFDTLDGINPLTDDISELIP
Mvan_1936|M.vanbaalenii_PYR-1       NLDDFVRPVRNYFYWEPHCYNIPVCATMRSVFDTLDGINPLTDDIQELIP
MUL_0757|M.ulcerans_Agy99           DFDDFFRPIRSYFYWEKHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLP
MMAR_0775|M.marinum_M               DFDDFWRPIRSYFYWEKHCYDVPICWSLRSIFDALDGVDKITEKLAALSR
MSMEG_0382|M.smegmatis_MC2_155      IFDDLLRPIRNYFYWEPHCYNIPICWSLRSIFDAMDGVDRLNDELQVLVD
TH_3056|M.thermoresistible__bu      DFDDFFRPIRNYFHWEPHCYNIPICWSIRSIFDALDGINEMTEKMEELVE
MLBr_02378|M.leprae_Br4923          NFDDFWRPIRSYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVG
Rv1557|M.tuberculosis_H37Rv         ------------------------GWMVRSVFDTIDGIDQLGEQLASVTV
Mb1583|M.bovis_AF2122/97            NFDDFFRPIRSYFYWEKHCYDIPSCWALRSVFDTIDGIDQLGEQLASVTV
MAV_3863|M.avium_104                NFDDFFRPVRSYFYWEKHCFDIPACFAFRSVFDALDGIDELSAQFEKLTA
MAB_0987c|M.abscessus_ATCC_199      NFDDQFRPIRNYFYWEPHCFDIPFCAALRSVFDALDGIDELVDALQSVTG
                                                               .**:**::**:: :   :  :  

Mflv_4418|M.gilvum_PYR-GCK          DLERLDELMPQLIALLPSQIETMRSMQAMMLRQYQTQKGQLDQNAAMSED
Mvan_1936|M.vanbaalenii_PYR-1       DLERLDALMPQLIALLPSQIESMRNMQSMMLTMYQSQKGLQDQMASQSED
MUL_0757|M.ulcerans_Agy99           LMERLDTLMPQMTAMMPEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQED
MMAR_0775|M.marinum_M               DMDRLDILMPQMRAQIPFQIASMKTMKTMMLTMHSSMSSLYDQMDEMSKN
MSMEG_0382|M.smegmatis_MC2_155      NMDRLDALVPELVAQFPEYIASMETFRELTLTSYSTFSGLLQQMDEQTED
TH_3056|M.thermoresistible__bu      DMDRLDALMPQMLVQFPQMIETMESSRTMILTMHATMSGIFDQMESSSEN
MLBr_02378|M.leprae_Br4923          DIKNMDLLMPQMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDN
Rv1557|M.tuberculosis_H37Rv         TLDKLAAIQPQLVALLPDEIASQQINRELALANYATMSGIYAQTAALIEN
Mb1583|M.bovis_AF2122/97            TLDKLAAIQPQLVALLPDEIASQQINRELALANYATMSGIYAQTAALIEN
MAV_3863|M.avium_104                SLDKLDAGQQKLVTLLPPQIADQEKNLALTLSNYATNLGINAQTRANTDT
MAB_0987c|M.abscessus_ATCC_199      SLTKLDALQPKLVDLIPPQIAIQEKNRDLTLSNYAINNGTNTQNEESTRT
                                     : .:     ::   :*  *   .      *  :    .   *       

Mflv_4418|M.gilvum_PYR-GCK          ADAMGEAFDDSMNDDSFYLPPEAFDNDDFKRGMENFISPDGRSVRFIISH
Mvan_1936|M.vanbaalenii_PYR-1       ADAMGEAFDDSMNDDSFYLPPEAFDNDDFKRGIENFISPDGKSVRFIIAH
MUL_0757|M.ulcerans_Agy99           SSAMGEAFDSSRNDDSFYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISH
MMAR_0775|M.marinum_M               STAMGKAFDAARNDDSFYIPPEVFDNADFKRGLKMFLSPDGHAVRFIISH
MSMEG_0382|M.smegmatis_MC2_155      VTAMGQAFDAAKNDDTFFLPPEVFDNPDFKRAMTSFLSPDGKAARFIISH
TH_3056|M.thermoresistible__bu      ATAMGKAFDASHNDDSFYLPPEALENKDFQRVMEIFLSPDGKAARMLVTQ
MLBr_02378|M.leprae_Br4923          ANTMGKAFDTAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILH
Rv1557|M.tuberculosis_H37Rv         AAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAARMIISH
Mb1583|M.bovis_AF2122/97            AAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAARMIISH
MAV_3863|M.avium_104                ATALGQAYDAAKNDDSFYLPPEAFTNPEFKRGLKLFLSPDGKAARMIISH
MAB_0987c|M.abscessus_ATCC_199      ATELGKAFDDAKNDDSFYLPPEAFDNPAFKRGMKLFMSPDGKAARMIITH
                                       :*:*:* : ***:*::***.: *  *:* :  *:*.**::.*::: :

Mflv_4418|M.gilvum_PYR-GCK          EGDPATVEGISEVVPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMSDGA
Mvan_1936|M.vanbaalenii_PYR-1       EGDPATVEGISRVLPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMRDGA
MUL_0757|M.ulcerans_Agy99           EGDPMSQAGINHIDKIKTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGN
MMAR_0775|M.marinum_M               EGDPASTEGISHVKPIMDEAKQAIKGTPLEGAKIYLAGTASVYKDMRDGS
MSMEG_0382|M.smegmatis_MC2_155      NGDPATPEGISRVDQMQTAAVEALKGTPLTDAQVYLAGTAPTAKDWKDGS
TH_3056|M.thermoresistible__bu      RGDPATPEGMALVEPIYIAAEEALKGTPLESSRIYLAGSAAGVKDLVEGA
MLBr_02378|M.leprae_Br4923          RGDPASVAGIASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGA
Rv1557|M.tuberculosis_H37Rv         EGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGA
Mb1583|M.bovis_AF2122/97            EGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGA
MAV_3863|M.avium_104                EGDPATPEGISHIEPIRNAAKQAVKNTPLGDSNIYLAGTAATYKDIAEGA
MAB_0987c|M.abscessus_ATCC_199      QGDPQTSEGIAHIDAIKEAAFDAVKATPLADAKIYVAGTASAYKDIADGQ
                                    .*** :  *:  :  :   * :*:* **: .: :*:.*:..  **  :* 

Mflv_4418|M.gilvum_PYR-GCK          FYDLLIAGIAAVTLIFVIMLVITRSVVAAAVIVGTVLLSLGASFGLSVLL
Mvan_1936|M.vanbaalenii_PYR-1       NYDLLIAGIAAVTLIFVIMLIITRSVVAAAVIVGTVLLSLGASFGLSVLL
MUL_0757|M.ulcerans_Agy99           TFDLMIAGISALCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLI
MMAR_0775|M.marinum_M               RWDLLIAGVAAVSLILIIMLIITRSLVAAVVIVGTVLLSLGASFGLSVLV
MSMEG_0382|M.smegmatis_MC2_155      TYDLLIAGIAAMCLIFIIMLIVTRSFIAALVIVGTVVLSLGASFGLSVLL
TH_3056|M.thermoresistible__bu      KYDLMIAAISAVCLIFMIMVFMTRSVIAALVIVGTVVLSLGASFGMSVLL
MLBr_02378|M.leprae_Br4923          NWDLVIAGISSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLL
Rv1557|M.tuberculosis_H37Rv         TYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLV
Mb1583|M.bovis_AF2122/97            TYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLV
MAV_3863|M.avium_104                KYDLLIAGIAALSLILLIMVLITRSLVAAIVIVGTVALSLGASFGLSVLV
MAB_0987c|M.abscessus_ATCC_199      KYDLLMAALASLGLILLIMMFLTRSLVAALVIVGTVALSLAASFGMSVVV
                                     :**::*.:::: **::**:.:**:.:** ****** ***.****:**::

Mflv_4418|M.gilvum_PYR-GCK          WQHIIGLALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELSGGLKTGIIR
Mvan_1936|M.vanbaalenii_PYR-1       WQHIIGLALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELAGGLKTGIIR
MUL_0757|M.ulcerans_Agy99           WQHVLGIELHWLVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIR
MMAR_0775|M.marinum_M               WQDIFGVELHWMVLAMSVILLLAVGSDYNLLLVSRLKEEIGAGLKTGIIR
MSMEG_0382|M.smegmatis_MC2_155      WQYILGIHLHWMVLAMSVIILLAVGSDYNLLLVSRIKEEVGAGINTGIVR
TH_3056|M.thermoresistible__bu      WQHLLGIQLHWVVLAMSVIVLLAVGSDYNLMLVSRMKEEIGAGLNTGIIR
MLBr_02378|M.leprae_Br4923          WQHILGIELHYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIR
Rv1557|M.tuberculosis_H37Rv         WQHLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIR
Mb1583|M.bovis_AF2122/97            WQHLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIR
MAV_3863|M.avium_104                WQDILGIKLYWICLALSVIILLAVGSDYNLLLISRFREEIHAGLNTGIIR
MAB_0987c|M.abscessus_ATCC_199      WQYIFGIPLYWVIFPLAVIILLAVGADYNLLLISRFKEETGAGLKTGIIR
                                    ** ::*: *::: :.::**:*****:****:*::*:::*  .*::***:*

Mflv_4418|M.gilvum_PYR-GCK          AMAGTGSVVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVR
Mvan_1936|M.vanbaalenii_PYR-1       SMAGTGSVVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVR
MUL_0757|M.ulcerans_Agy99           AMGGSGSVVTAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVR
MMAR_0775|M.marinum_M               AMAGTGGVVTTAGLVFAATMASFIFSDLRVIGQVGTTIGLGLLFDTLIVR
MSMEG_0382|M.smegmatis_MC2_155      AMGGTGKVVTSAGLVFAGTMAAMVVSDLRIIGQIGTTIGLGLLFDTMIVR
TH_3056|M.thermoresistible__bu      AMGGTGRVVTMAGLVFAATMASMIVSDLLMIGQVGTTIALGLLFDTMVVR
MLBr_02378|M.leprae_Br4923          SMGGTGKVVTNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVR
Rv1557|M.tuberculosis_H37Rv         AMAGTGGVVTAAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVR
Mb1583|M.bovis_AF2122/97            AMAGTGGVVTAAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVR
MAV_3863|M.avium_104                SMAGSGAVVTSAGLVFAFTMASFVSASLLVLGQIGTTIALGLLFDTLIVR
MAB_0987c|M.abscessus_ATCC_199      AIAGTGGVVTAAGLVFAVTMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVR
                                    ::.*:* *** ****** ** ::  :.* ::.*:****.:******::**

Mflv_4418|M.gilvum_PYR-GCK          SFMTPAVAALLGRWFWWPQKFRSAASERRLARIGVQPATAGR--------
Mvan_1936|M.vanbaalenii_PYR-1       SFMTPAVAALLGRWFWWPQKVRSHASQRRLAALNH---------------
MUL_0757|M.ulcerans_Agy99           SFMTPSIAALLGKWFWWPQVVRQRPAPQPWPTPAPTPPPATTSV------
MMAR_0775|M.marinum_M               SFMTPSIAALMGRWFWWPQQVRTRPASQLLRPYGPRPLVRALLLPRNGDS
MSMEG_0382|M.smegmatis_MC2_155      SFMTPSIAALLGRWFWWPQKVRPRPASALLEPYGPRPLVRALLEGPSGAA
TH_3056|M.thermoresistible__bu      AFMTPSVAAILGRWFWWPQRVRTRPASAMLRPVGPRPLVRSLLLRD----
MLBr_02378|M.leprae_Br4923          SFMMPSIAALLGRWFWWPQQGRTRPLLTVAAPVG-LPPDRSLVYSD----
Rv1557|M.tuberculosis_H37Rv         AFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGPRPVVRELLLREGND-
Mb1583|M.bovis_AF2122/97            AFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGPRPVVRELLLREGND-
MAV_3863|M.avium_104                SFMTPSVAALLGRWFWWPQRVRPRPASTMLRPYGPRPAVRQLLLWEDGDP
MAB_0987c|M.abscessus_ATCC_199      SFLTPAIATMLGRWFWWPINIRTRPAP---KPFGPKPTG--------AD-
                                    :*: *::*.::*:*****   *  .                         

Mflv_4418|M.gilvum_PYR-GCK          ----------------------
Mvan_1936|M.vanbaalenii_PYR-1       ----------------------
MUL_0757|M.ulcerans_Agy99           ----------------------
MMAR_0775|M.marinum_M               ADGPEDTNTERLAVSSPHY---
MSMEG_0382|M.smegmatis_MC2_155      SPGGPGGRLSDDDTPTGPMRTR
TH_3056|M.thermoresistible__bu      ----------------------
MLBr_02378|M.leprae_Br4923          ----------------------
Rv1557|M.tuberculosis_H37Rv         --DPRTQVATHR----------
Mb1583|M.bovis_AF2122/97            --DPRTQVATHR----------
MAV_3863|M.avium_104                AVAPETPSAARHSRG-------
MAB_0987c|M.abscessus_ATCC_199      --DTTGPIPVSG----------