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VQGISVTGLVKRGWMVRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALA NYATMSGIYAQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAARMIISHEG DPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLLIAGIAALSLILLIMMII TRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGA GLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAVLLG RWFWWPQRVRPRPASRMLRPYGPRPVVRELLLREGNDDPRTQVATHR
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv1557 | mmpL6 | - | 100% (397) | PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL6 |
M. tuberculosis H37Rv | Rv0507 | mmpL2 | e-148 | 68.78% (378) | transmembrane transport protein MmpL2 |
M. tuberculosis H37Rv | Rv0450c | mmpL4 | e-134 | 63.96% (369) | transmembrane transport protein MmpL4 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1583 | mmpL6 | 0.0 | 99.48% (384) | transmembrane transport protein MmpL6 |
M. gilvum PYR-GCK | Mflv_4418 | - | 1e-135 | 64.09% (362) | transport protein |
M. leprae Br4923 | MLBr_02378 | - | 1e-130 | 63.26% (362) | hypothetical protein MLBr_02378 |
M. abscessus ATCC 19977 | MAB_0987c | - | 1e-144 | 70.56% (360) | membrane protein MmpL |
M. marinum M | MMAR_0775 | - | 1e-150 | 67.65% (374) | MmpL family transport protein |
M. avium 104 | MAV_3863 | - | 1e-158 | 76.28% (371) | MmpL4 protein |
M. smegmatis MC2 155 | MSMEG_0382 | - | 1e-148 | 67.93% (368) | putative transport protein |
M. thermoresistible (build 8) | TH_3056 | - | 1e-141 | 64.42% (371) | PUTATIVE Mmp14a protein |
M. ulcerans Agy99 | MUL_0757 | mmpL5 | 1e-133 | 62.43% (362) | transmembrane transport protein, MmpL5 |
M. vanbaalenii PYR-1 | Mvan_1936 | - | 1e-133 | 65.16% (353) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_4418|M.gilvum_PYR-GCK ---------------------------------MADAGRSGIGRIIRVLA Mvan_1936|M.vanbaalenii_PYR-1 ---------------------------------MADAGRSGIGRIIHLLA MUL_0757|M.ulcerans_Agy99 ------------------MTATTTDTPTDVVPPAEHPPRPFIPRMIRTFA MMAR_0775|M.marinum_M MSDDQAVSERAASNGASNGAGAENGNGNENGNGNGNGSRPSMARLIHRMA MSMEG_0382|M.smegmatis_MC2_155 --------------------------MSTEQSGTEKARRPFFARAVRTLS TH_3056|M.thermoresistible__bu --------------------------MSVLDRVGVEPRRPRVASFIRRYS MLBr_02378|M.leprae_Br4923 ------------------------MTVKCANDLDTHTKPPFVARMIHRFA Rv1557|M.tuberculosis_H37Rv -------------------------------------------------- Mb1583|M.bovis_AF2122/97 -------------------------------MSNHHRPRPWLPHTIRRLS MAV_3863|M.avium_104 -------------------------------MTTDQATRSVVAQTIRRLS MAB_0987c|M.abscessus_ATCC_199 -------------------------------MSANHAHESRAAKIVRRLA Mflv_4418|M.gilvum_PYR-GCK VPIVLGWVLLTVLTN---------VAVPSLEKVGEEHTVGMSAGDAPSMM Mvan_1936|M.vanbaalenii_PYR-1 VPIVLGWIALTVLTN---------VAVPSLEKVGEEHTVGMSANDAPSMM MUL_0757|M.ulcerans_Agy99 VPLILGWVLLIAVLN---------SVVPQLEVVGQMQAVSMSPDAAPSMI MMAR_0775|M.marinum_M VPIVVFWVGLVAVLV---------MFVPSLEEVGKQHTVSLSPSDAESMI MSMEG_0382|M.smegmatis_MC2_155 PFIIVGWLAVILVTTLAAVGGDWSAAIPALERVGEKNSVSLMPQDAPSAK TH_3056|M.thermoresistible__bu VLIILGWVALTVLAT---------VAVPPLEAVEREKSLSLIPYDAPAFA MLBr_02378|M.leprae_Br4923 VPIILVWLAIAVTVS---------VFIPSLEDVGQERSVSLSPKDAPSYI Rv1557|M.tuberculosis_H37Rv -------------------------------------------------- Mb1583|M.bovis_AF2122/97 LPILLFWVGVAAITN---------AAVPQLEVVGEAHNVAQSSPDDPSLQ MAV_3863|M.avium_104 VPILLVWVAVAAISN---------IAVPNLEDVAKAHNVSLNTPAAPSFQ MAB_0987c|M.abscessus_ATCC_199 VPIVLFWVAIAAVTN---------ATVPQLEVVGEERSAPLNAADAPSTL Mflv_4418|M.gilvum_PYR-GCK SMKRVGANFEEFDSDSSAMVVLEGEQPLGDAAHRYYDQLIDELEADTANV Mvan_1936|M.vanbaalenii_PYR-1 SMERVGANFDEFDSDSSAMVVLEGEQPLGDAAHRYYDELIGKLEADTANV MUL_0757|M.ulcerans_Agy99 SMKHIGKVFREGDSDSAAMIVLEGQEPLGAAAHKFYDKMITKLRADTKHV MMAR_0775|M.marinum_M AMKRVGKVFNEFDTDSAVMIVLEGDHPLGDEAHHYYDELVRKLKADKDHV MSMEG_0382|M.smegmatis_MC2_155 AMKHMGQKFEESDSDSFAMIVLEGQEPLGPDALDYYTGLISELRNDSKHV TH_3056|M.thermoresistible__bu AMHRMGELFDEPDSESIAIIVLEGQEPLGLEAHEYYDQLISQLREHPQYV MLBr_02378|M.leprae_Br4923 AMQKMGQVFNEGNSDSVIMIVLEGDKPLGDDAHRFYDGLIRKLRAD-KHV Rv1557|M.tuberculosis_H37Rv -------------------------------------------------- Mb1583|M.bovis_AF2122/97 AMKRIGKVFHEFDSDSAAMIVLEGDKPLGNDAHRFYDTLLRNLSNDTKHV MAV_3863|M.avium_104 AMQHIGKVFHEYDSDSAAMIVLEGDKPLGDDAHRFYDALVGKLEHDTKHV MAB_0987c|M.abscessus_ATCC_199 AMRHIGKVFNEFDSDSSAMVVLEGEKPLGAQAHQFYNTLVQRLNDDHEHV Mflv_4418|M.gilvum_PYR-GCK QHIADFWGDPLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIV Mvan_1936|M.vanbaalenii_PYR-1 QHVADFWGDPLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIV MUL_0757|M.ulcerans_Agy99 QSVQDFWGDPLTATGAQSGDGKAAYVQVKLAGNQGESLANESVEAVKTIV MMAR_0775|M.marinum_M QHVQDFWGDPLTAAGSQSPDGKAAYVQAYLVGNQGEAKANESVDAVRELV MSMEG_0382|M.smegmatis_MC2_155 EHVQDLWGDRLTASSAQSADGKAAYVQLNLAGNQGTPLGDESVAAVRDLV TH_3056|M.thermoresistible__bu QHIRDFWGDPLTAGAAQSDDGKAAFVQVNLVGRFGQAKVNEAVRAVQEIV MLBr_02378|M.leprae_Br4923 QSVQDFWGDPLTAPGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIV Rv1557|M.tuberculosis_H37Rv -------------------------------------------------- Mb1583|M.bovis_AF2122/97 EHVQDFWGDPLTAAGSQSTDGKAAYVQVYLAGNQGEALSIESVDAVRDIV MAV_3863|M.avium_104 EHVQNFWGDPLTAAGSQSKDGKAAYVQVYLAGNQGDALANESVDAIRNIV MAB_0987c|M.abscessus_ATCC_199 QHVADYWGDPITAGGSQSKDGKAAYVQVYVAGNQGEALSNESVDAVRRII Mflv_4418|M.gilvum_PYR-GCK DRTPAPPGIKAYVTGGAPLVADQHSAGDTSVLRVTLITIGVIAVMLLIVF Mvan_1936|M.vanbaalenii_PYR-1 DQTPAPPGLKAYVTGGAPLVADQHNAGDKSVFRVTLITIGVIAVMLLLVF MUL_0757|M.ulcerans_Agy99 DSLQAPPGVKVYVTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVY MMAR_0775|M.marinum_M NDTPAPPGVKAYVTGPAALIADQSTAGDASIQRVTFITIGVIFVMLLSVY MSMEG_0382|M.smegmatis_MC2_155 ARTPAPEGVSVYVTGAAPLVSDMQHSGNRSILKITAVTVVIIFAMLLMVY TH_3056|M.thermoresistible__bu ERTPAPEGVETFVTGPAALGADAGDSGTATVILITLVTVAVIFLMLLFFF MLBr_02378|M.leprae_Br4923 VQTPAPPGITAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVY Rv1557|M.tuberculosis_H37Rv -------------------------------------------------- Mb1583|M.bovis_AF2122/97 AHTPPPAGVKAYVTGAAPLMADQFQVGSKGTAKVTGITLVVIAVMLLFVY MAV_3863|M.avium_104 EHTPPPPGVKAYVTGAAPLVTDQFEVGSKGIFKVTVITVLVILAMLLWVY MAB_0987c|M.abscessus_ATCC_199 AETPAPDGIKAYVSGEAPTITDQFEVGNAGAAQVTIITFAVIAVMLLVVY Mflv_4418|M.gilvum_PYR-GCK RSVATMVLILFMVFAELGAARGIVAFLADAEIIGLSTFATSLLTLMVIAA Mvan_1936|M.vanbaalenii_PYR-1 RSVATMVLILFMVFAELGAARGIVAFLANAEIIGLSTFATSLLTLMVIAA MUL_0757|M.ulcerans_Agy99 RSIITAAIMLTMVVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAA MMAR_0775|M.marinum_M RSLITVISVLVMVGIELMAARGVVAFLADNNVIGLSTFAVNLLVLMAIAA MSMEG_0382|M.smegmatis_MC2_155 RSVITVILLLIMVGFEVAAARGIVAFLGANEVFVLSTFAVNMLVFLAIAA TH_3056|M.thermoresistible__bu RSFLTVIVLLLTVAVELQVARGLVAYLGLQGWVGLTTYVVNLLVSVGIAA MLBr_02378|M.leprae_Br4923 RSFITVILLLFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAA Rv1557|M.tuberculosis_H37Rv -------------------------------------------------- Mb1583|M.bovis_AF2122/97 RSVVTMVLVLITVLIELAAARGIVAFLGNAGVIGLSTYSTNLLTLLVIAA MAV_3863|M.avium_104 RS-VTAVFVLVTVIVEMAAARGIVAFLGSVGLIGLSTYATNLLTLLVIAA MAB_0987c|M.abscessus_ATCC_199 RSLITTALVLAMVMVELSAARGIVAALGHTGVIGLSTYATNLLTMLAIAA Mflv_4418|M.gilvum_PYR-GCK GTDYAIFAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLC Mvan_1936|M.vanbaalenii_PYR-1 GTDYAIFAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLC MUL_0757|M.ulcerans_Agy99 ATDYAIFLIGRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFC MMAR_0775|M.marinum_M GTDYAIFVLGRYQEARGEGESREKAFYTMFHGTAHVVLGSGLTIAGAMYC MSMEG_0382|M.smegmatis_MC2_155 GTDYGIFFFGRYQEARAAGEDRETAYYSMYRGVTPVVMASGLTIAGAIFC TH_3056|M.thermoresistible__bu GTDYGIFFFGRYQEAREAGEDRDSAYFTTYRSVAKVVLASGLTIAGAIAC MLBr_02378|M.leprae_Br4923 GTDYGIFITGRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFC Rv1557|M.tuberculosis_H37Rv -------------------------------------------------- Mb1583|M.bovis_AF2122/97 GTDYAIFVLGRYHEARYAAQDRETAFYTMYRGTAHVVLGSGLTVAGAVYC MAV_3863|M.avium_104 GTDYAIFFVGRYHEARHEGQDRETAYYTMYRGTTHVVLGSGLTVAGAVLC MAB_0987c|M.abscessus_ATCC_199 GTDYAIFFVGRYQEARSAGEDRPSAYQTMYKSTAHVIIGSGLTVAGALFC Mflv_4418|M.gilvum_PYR-GCK LSFTRLPYFQTMGVPCAVGTFVAVIAALTLGPAVIVIGSRFG-LFDPKRA Mvan_1936|M.vanbaalenii_PYR-1 LSFTRLPYFQTMGVPCAVGTFVAVMAALTLGPAVVAIGSRFG-LFDPKRA MUL_0757|M.ulcerans_Agy99 LSFTRLPYFQTLGVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPKRM MMAR_0775|M.marinum_M LSFTRLPYFQTLGAPCAVGMLVAVLAALTLGPAVLVVGSFFK-LFDPKRK MSMEG_0382|M.smegmatis_MC2_155 LTFTRLPYFHTMGVPCAIGMLAAVAVAVTLVPAGVALAGRIG-WLEPKRK TH_3056|M.thermoresistible__bu LSFTRLPHFQPLGIPGAVGLLVAVAVALTLVPATIALGSRFG-LFEPKRR MLBr_02378|M.leprae_Br4923 LSFARMPYFQTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRL Rv1557|M.tuberculosis_H37Rv -------------------------------------------------- Mb1583|M.bovis_AF2122/97 LSFTRLPYFQSLGIPASIGVMIALAAALSLAPSVLILGSRFG-CFEPKRR MAV_3863|M.avium_104 LRFTRLNYFQSLGIPAAIGIGVALAAALSLTPAVITVGSLFG-LFDPKRQ MAB_0987c|M.abscessus_ATCC_199 LSFTRLPYFQTLGVPAALGVLVTLAAALTLAPAVLVIAGRFG-LMEPKRA Mflv_4418|M.gilvum_PYR-GCK ISSRGWRRIGVSVVRWPGPVLAATLALALVGLVTLPGYKTNYDARDYLPE Mvan_1936|M.vanbaalenii_PYR-1 ISSRGWRRIGVSVVRWPGPVLAATLALALVGLVALPGYKTNYDSRDYLPE MUL_0757|M.ulcerans_Agy99 ARVRGWRKIGAAIVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLPA MMAR_0775|M.marinum_M MRTRGWRRVGTAIVRWPGPILAVSIAIALIGLLALPGYRTNYDSKKYLPA MSMEG_0382|M.smegmatis_MC2_155 MRVRRWRGIGTAIVRWPAPILVASLAVALVGLLALPGYETSYNDRDYIPA TH_3056|M.thermoresistible__bu VMTHRWRRIGTAVVRWPVPILTAAVALSLVGLLTLPGYNPSYSDQEFIPD MLBr_02378|M.leprae_Br4923 IKVRGWRRIGTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPA Rv1557|M.tuberculosis_H37Rv -------------------------------------------------- Mb1583|M.bovis_AF2122/97 MRTRGWRRIGTAIVRWPGPILAVACAIAVVGLLALPGYKTSYDARYYMPA MAV_3863|M.avium_104 MATRGWRRIGTAIVRWPGPILVVATGVALVGLLALPGYRTNYDARPYMPA MAB_0987c|M.abscessus_ATCC_199 MRTRGWRRIGTAIVRWPGPILVVSCIATLVGLLALPGYRTTYDGRIYMPS Mflv_4418|M.gilvum_PYR-GCK DIPANVGYAVADQHFGSARMN-PELLMVESDHDLRNPADFLVIDKIAKSV Mvan_1936|M.vanbaalenii_PYR-1 DVPANVGYAVADRHFGSARMN-PELLMVESDHDLRNPADFLVIDKIAKAI MUL_0757|M.ulcerans_Agy99 DLPANEGYSAAERHFSQARMN-PEVLMVESDHDMRNSSDFLVINKIAKAI MMAR_0775|M.marinum_M STPTNVGYTAADRHFSQARMN-PELLMVETDHDMRNPADMLVIDRIAKGV MSMEG_0382|M.smegmatis_MC2_155 DIPANAGFAAADRHFSQARMT-PDILMVESDHDMRNPTDFLVLNKIAKAI TH_3056|M.thermoresistible__bu DIPASEGYKAAARHFPASAMSVPDVVLIEADRDMRNPADLLVLNKVAKKI MLBr_02378|M.leprae_Br4923 SIPANQGFAAADRHFPQARMK-PEILMIESDHDMRNPADFLILDKLARGI Rv1557|M.tuberculosis_H37Rv -------------------------------------------------- Mb1583|M.bovis_AF2122/97 TAPANIGYMAAERHFPQARLN-PELLMIETDHDMRNPADMLILDRIAKAV MAV_3863|M.avium_104 SAPANTGYTAAERHFSQARLN-PELLMIETDHDMRNPADMINLERVAKAI MAB_0987c|M.abscessus_ATCC_199 SVPSNVGYAAAERHFSVARLN-PELLMIETDFDMRNPAGMVLLERVAKSV Mflv_4418|M.gilvum_PYR-GCK FRVPGVARVQTITRPDGKPIKHTTIPFQMSMQGTTQRLNEKYLQDRMADM Mvan_1936|M.vanbaalenii_PYR-1 FRVPGVARVQTITRPDGKPIKHTTIPFQMSMRSTTSRLNEKYMQDRMADM MUL_0757|M.ulcerans_Agy99 FGVEGISRVQAITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSM MMAR_0775|M.marinum_M FHLPGVARVQAVTRPLGKPIEHSSIPFQISMQNTVQVENMQYMKQRMADM MSMEG_0382|M.smegmatis_MC2_155 FKVRGVSRVQGITRPEGTPIERTSIPFLLSLQSAGQVQATNFQKQRIGDM TH_3056|M.thermoresistible__bu FEVPGVANVQSVTRPEGRQIEHTTIPFMLSMSQASQRLALPFQRARMDDM MLBr_02378|M.leprae_Br4923 FRVPGISRVQAITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDL Rv1557|M.tuberculosis_H37Rv --MQGISVTGLVKR------------------------------------ Mb1583|M.bovis_AF2122/97 FHLPGIGLVQAMTRPLGTPIDHSSIPFQISMQSVGQIQNLKYQRDRAADL MAV_3863|M.avium_104 AHLPGIAQVQSMTRPLGTPIEHTSLAFQISAGSIGSIENLQYQKERAEDL MAB_0987c|M.abscessus_ATCC_199 LHARGVALVQSITRPLGTPITHSSIPFQISASSASQLMNLSQQQNQALYL *:. . :.* Mflv_4418|M.gilvum_PYR-GCK LVQADAMQTNVDTMTRMQSLMGQMSATTHEMVLKTKKTEIDIIEVRDNLA Mvan_1936|M.vanbaalenii_PYR-1 LVQADAMQTNVDTMTKMQSLMTQMSAATHDMVTKTKKTAVDIVEVRDYLA MUL_0757|M.ulcerans_Agy99 LQQVNDIQTNIDQMERMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIA MMAR_0775|M.marinum_M LIQAAAMQDSIDTLDRMYDIMGKMVETTHDMDGLTHDMVEITDELRDHIA MSMEG_0382|M.smegmatis_MC2_155 LKQVDDMNMMIGVMKTTYGVLQELAATTHSLNGSTHELRDVARDLRGSIA TH_3056|M.thermoresistible__bu LKQADELTETIALMRRMQSLMEKMVATTHSMVGTTHELLDTTRDLRDHIA MLBr_02378|M.leprae_Br4923 LRQAENMAETIASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIA Rv1557|M.tuberculosis_H37Rv -------------------------------------------------- Mb1583|M.bovis_AF2122/97 LKQAEELGKTIEILQRQYALQQELAAATHEQAESFHQTIATVKELRDRIA MAV_3863|M.avium_104 LKQADNLKDTIGILNQQYALQKQLAASTHDETQSFHDTIAIINDLRDKIA MAB_0987c|M.abscessus_ATCC_199 SQQADQMTNTIAVLRQQLALQKQSAAITHEQTEGFQQTVAVAQDLRDKIA Mflv_4418|M.gilvum_PYR-GCK DFDDFFRPVRNYFYWEPHCYDIPVCWTMRSVFDTLDGINPLTDDISELIP Mvan_1936|M.vanbaalenii_PYR-1 NLDDFVRPVRNYFYWEPHCYNIPVCATMRSVFDTLDGINPLTDDIQELIP MUL_0757|M.ulcerans_Agy99 DFDDFFRPIRSYFYWEKHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLP MMAR_0775|M.marinum_M DFDDFWRPIRSYFYWEKHCYDVPICWSLRSIFDALDGVDKITEKLAALSR MSMEG_0382|M.smegmatis_MC2_155 IFDDLLRPIRNYFYWEPHCYNIPICWSLRSIFDAMDGVDRLNDELQVLVD TH_3056|M.thermoresistible__bu DFDDFFRPIRNYFHWEPHCYNIPICWSIRSIFDALDGINEMTEKMEELVE MLBr_02378|M.leprae_Br4923 NFDDFWRPIRSYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVG Rv1557|M.tuberculosis_H37Rv ------------------------GWMVRSVFDTIDGIDQLGEQLASVTV Mb1583|M.bovis_AF2122/97 NFDDFFRPIRSYFYWEKHCYDIPSCWALRSVFDTIDGIDQLGEQLASVTV MAV_3863|M.avium_104 NFDDFFRPVRSYFYWEKHCFDIPACFAFRSVFDALDGIDELSAQFEKLTA MAB_0987c|M.abscessus_ATCC_199 NFDDQFRPIRNYFYWEPHCFDIPFCAALRSVFDALDGIDELVDALQSVTG .**:**::**:: : : : Mflv_4418|M.gilvum_PYR-GCK DLERLDELMPQLIALLPSQIETMRSMQAMMLRQYQTQKGQLDQNAAMSED Mvan_1936|M.vanbaalenii_PYR-1 DLERLDALMPQLIALLPSQIESMRNMQSMMLTMYQSQKGLQDQMASQSED MUL_0757|M.ulcerans_Agy99 LMERLDTLMPQMTAMMPEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQED MMAR_0775|M.marinum_M DMDRLDILMPQMRAQIPFQIASMKTMKTMMLTMHSSMSSLYDQMDEMSKN MSMEG_0382|M.smegmatis_MC2_155 NMDRLDALVPELVAQFPEYIASMETFRELTLTSYSTFSGLLQQMDEQTED TH_3056|M.thermoresistible__bu DMDRLDALMPQMLVQFPQMIETMESSRTMILTMHATMSGIFDQMESSSEN MLBr_02378|M.leprae_Br4923 DIKNMDLLMPQMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDN Rv1557|M.tuberculosis_H37Rv TLDKLAAIQPQLVALLPDEIASQQINRELALANYATMSGIYAQTAALIEN Mb1583|M.bovis_AF2122/97 TLDKLAAIQPQLVALLPDEIASQQINRELALANYATMSGIYAQTAALIEN MAV_3863|M.avium_104 SLDKLDAGQQKLVTLLPPQIADQEKNLALTLSNYATNLGINAQTRANTDT MAB_0987c|M.abscessus_ATCC_199 SLTKLDALQPKLVDLIPPQIAIQEKNRDLTLSNYAINNGTNTQNEESTRT : .: :: :* * . * : . * Mflv_4418|M.gilvum_PYR-GCK ADAMGEAFDDSMNDDSFYLPPEAFDNDDFKRGMENFISPDGRSVRFIISH Mvan_1936|M.vanbaalenii_PYR-1 ADAMGEAFDDSMNDDSFYLPPEAFDNDDFKRGIENFISPDGKSVRFIIAH MUL_0757|M.ulcerans_Agy99 SSAMGEAFDSSRNDDSFYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISH MMAR_0775|M.marinum_M STAMGKAFDAARNDDSFYIPPEVFDNADFKRGLKMFLSPDGHAVRFIISH MSMEG_0382|M.smegmatis_MC2_155 VTAMGQAFDAAKNDDTFFLPPEVFDNPDFKRAMTSFLSPDGKAARFIISH TH_3056|M.thermoresistible__bu ATAMGKAFDASHNDDSFYLPPEALENKDFQRVMEIFLSPDGKAARMLVTQ MLBr_02378|M.leprae_Br4923 ANTMGKAFDTAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILH Rv1557|M.tuberculosis_H37Rv AAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAARMIISH Mb1583|M.bovis_AF2122/97 AAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAARMIISH MAV_3863|M.avium_104 ATALGQAYDAAKNDDSFYLPPEAFTNPEFKRGLKLFLSPDGKAARMIISH MAB_0987c|M.abscessus_ATCC_199 ATELGKAFDDAKNDDSFYLPPEAFDNPAFKRGMKLFMSPDGKAARMIITH :*:*:* : ***:*::***.: * *:* : *:*.**::.*::: : Mflv_4418|M.gilvum_PYR-GCK EGDPATVEGISEVVPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMSDGA Mvan_1936|M.vanbaalenii_PYR-1 EGDPATVEGISRVLPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMRDGA MUL_0757|M.ulcerans_Agy99 EGDPMSQAGINHIDKIKTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGN MMAR_0775|M.marinum_M EGDPASTEGISHVKPIMDEAKQAIKGTPLEGAKIYLAGTASVYKDMRDGS MSMEG_0382|M.smegmatis_MC2_155 NGDPATPEGISRVDQMQTAAVEALKGTPLTDAQVYLAGTAPTAKDWKDGS TH_3056|M.thermoresistible__bu RGDPATPEGMALVEPIYIAAEEALKGTPLESSRIYLAGSAAGVKDLVEGA MLBr_02378|M.leprae_Br4923 RGDPASVAGIASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGA Rv1557|M.tuberculosis_H37Rv EGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGA Mb1583|M.bovis_AF2122/97 EGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGA MAV_3863|M.avium_104 EGDPATPEGISHIEPIRNAAKQAVKNTPLGDSNIYLAGTAATYKDIAEGA MAB_0987c|M.abscessus_ATCC_199 QGDPQTSEGIAHIDAIKEAAFDAVKATPLADAKIYVAGTASAYKDIADGQ .*** : *: : : * :*:* **: .: :*:.*:.. ** :* Mflv_4418|M.gilvum_PYR-GCK FYDLLIAGIAAVTLIFVIMLVITRSVVAAAVIVGTVLLSLGASFGLSVLL Mvan_1936|M.vanbaalenii_PYR-1 NYDLLIAGIAAVTLIFVIMLIITRSVVAAAVIVGTVLLSLGASFGLSVLL MUL_0757|M.ulcerans_Agy99 TFDLMIAGISALCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLI MMAR_0775|M.marinum_M RWDLLIAGVAAVSLILIIMLIITRSLVAAVVIVGTVLLSLGASFGLSVLV MSMEG_0382|M.smegmatis_MC2_155 TYDLLIAGIAAMCLIFIIMLIVTRSFIAALVIVGTVVLSLGASFGLSVLL TH_3056|M.thermoresistible__bu KYDLMIAAISAVCLIFMIMVFMTRSVIAALVIVGTVVLSLGASFGMSVLL MLBr_02378|M.leprae_Br4923 NWDLVIAGISSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLL Rv1557|M.tuberculosis_H37Rv TYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLV Mb1583|M.bovis_AF2122/97 TYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLV MAV_3863|M.avium_104 KYDLLIAGIAALSLILLIMVLITRSLVAAIVIVGTVALSLGASFGLSVLV MAB_0987c|M.abscessus_ATCC_199 KYDLLMAALASLGLILLIMMFLTRSLVAALVIVGTVALSLAASFGMSVVV :**::*.:::: **::**:.:**:.:** ****** ***.****:**:: Mflv_4418|M.gilvum_PYR-GCK WQHIIGLALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELSGGLKTGIIR Mvan_1936|M.vanbaalenii_PYR-1 WQHIIGLALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELAGGLKTGIIR MUL_0757|M.ulcerans_Agy99 WQHVLGIELHWLVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIR MMAR_0775|M.marinum_M WQDIFGVELHWMVLAMSVILLLAVGSDYNLLLVSRLKEEIGAGLKTGIIR MSMEG_0382|M.smegmatis_MC2_155 WQYILGIHLHWMVLAMSVIILLAVGSDYNLLLVSRIKEEVGAGINTGIVR TH_3056|M.thermoresistible__bu WQHLLGIQLHWVVLAMSVIVLLAVGSDYNLMLVSRMKEEIGAGLNTGIIR MLBr_02378|M.leprae_Br4923 WQHILGIELHYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIR Rv1557|M.tuberculosis_H37Rv WQHLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIR Mb1583|M.bovis_AF2122/97 WQHLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIR MAV_3863|M.avium_104 WQDILGIKLYWICLALSVIILLAVGSDYNLLLISRFREEIHAGLNTGIIR MAB_0987c|M.abscessus_ATCC_199 WQYIFGIPLYWVIFPLAVIILLAVGADYNLLLISRFKEETGAGLKTGIIR ** ::*: *::: :.::**:*****:****:*::*:::* .*::***:* Mflv_4418|M.gilvum_PYR-GCK AMAGTGSVVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVR Mvan_1936|M.vanbaalenii_PYR-1 SMAGTGSVVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVR MUL_0757|M.ulcerans_Agy99 AMGGSGSVVTAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVR MMAR_0775|M.marinum_M AMAGTGGVVTTAGLVFAATMASFIFSDLRVIGQVGTTIGLGLLFDTLIVR MSMEG_0382|M.smegmatis_MC2_155 AMGGTGKVVTSAGLVFAGTMAAMVVSDLRIIGQIGTTIGLGLLFDTMIVR TH_3056|M.thermoresistible__bu AMGGTGRVVTMAGLVFAATMASMIVSDLLMIGQVGTTIALGLLFDTMVVR MLBr_02378|M.leprae_Br4923 SMGGTGKVVTNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVR Rv1557|M.tuberculosis_H37Rv AMAGTGGVVTAAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVR Mb1583|M.bovis_AF2122/97 AMAGTGGVVTAAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVR MAV_3863|M.avium_104 SMAGSGAVVTSAGLVFAFTMASFVSASLLVLGQIGTTIALGLLFDTLIVR MAB_0987c|M.abscessus_ATCC_199 AIAGTGGVVTAAGLVFAVTMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVR ::.*:* *** ****** ** :: :.* ::.*:****.:******::** Mflv_4418|M.gilvum_PYR-GCK SFMTPAVAALLGRWFWWPQKFRSAASERRLARIGVQPATAGR-------- Mvan_1936|M.vanbaalenii_PYR-1 SFMTPAVAALLGRWFWWPQKVRSHASQRRLAALNH--------------- MUL_0757|M.ulcerans_Agy99 SFMTPSIAALLGKWFWWPQVVRQRPAPQPWPTPAPTPPPATTSV------ MMAR_0775|M.marinum_M SFMTPSIAALMGRWFWWPQQVRTRPASQLLRPYGPRPLVRALLLPRNGDS MSMEG_0382|M.smegmatis_MC2_155 SFMTPSIAALLGRWFWWPQKVRPRPASALLEPYGPRPLVRALLEGPSGAA TH_3056|M.thermoresistible__bu AFMTPSVAAILGRWFWWPQRVRTRPASAMLRPVGPRPLVRSLLLRD---- MLBr_02378|M.leprae_Br4923 SFMMPSIAALLGRWFWWPQQGRTRPLLTVAAPVG-LPPDRSLVYSD---- Rv1557|M.tuberculosis_H37Rv AFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGPRPVVRELLLREGND- Mb1583|M.bovis_AF2122/97 AFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGPRPVVRELLLREGND- MAV_3863|M.avium_104 SFMTPSVAALLGRWFWWPQRVRPRPASTMLRPYGPRPAVRQLLLWEDGDP MAB_0987c|M.abscessus_ATCC_199 SFLTPAIATMLGRWFWWPINIRTRPAP---KPFGPKPTG--------AD- :*: *::*.::*:***** * . Mflv_4418|M.gilvum_PYR-GCK ---------------------- Mvan_1936|M.vanbaalenii_PYR-1 ---------------------- MUL_0757|M.ulcerans_Agy99 ---------------------- MMAR_0775|M.marinum_M ADGPEDTNTERLAVSSPHY--- MSMEG_0382|M.smegmatis_MC2_155 SPGGPGGRLSDDDTPTGPMRTR TH_3056|M.thermoresistible__bu ---------------------- MLBr_02378|M.leprae_Br4923 ---------------------- Rv1557|M.tuberculosis_H37Rv --DPRTQVATHR---------- Mb1583|M.bovis_AF2122/97 --DPRTQVATHR---------- MAV_3863|M.avium_104 AVAPETPSAARHSRG------- MAB_0987c|M.abscessus_ATCC_199 --DTTGPIPVSG----------