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TSDEDSPRHDLADADLRVTRGSVPASVQLAELLRTQILERALSPGSRLPTEQELIARSGVSRSTVRAAVG ILEDEGWLVRRQGLGTFVAEPVKQDLESGVRTITEVLLSRGVTPRVEVLSHAVVAAPQSVGAALGRSEVL RIQRRYSESDQPLAIVTCYLPADLPHDAVEPLLSATSATATTYTMWEQRLGVRISSATHEIQAAGASPEI AAALGLSEGAPVLVLRRTSYTDGDKPLEVVLFHHRPERYEFCVTLPRTMPGQRAGMTER*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2560 | - | - | 100% (270) | GntR family transcriptional regulator |
| M. marinum M | MMAR_4842 | - | 4e-15 | 27.04% (233) | regulatory protein |
| M. marinum M | MMAR_0304 | - | 7e-13 | 27.00% (237) | GntR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0816c | - | 2e-93 | 65.91% (264) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2603 | - | 9e-21 | 32.49% (237) | UbiC transcription regulator-associated domain-containing |
| M. tuberculosis H37Rv | Rv0792c | - | 3e-93 | 65.91% (264) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0953 | - | 7e-17 | 27.82% (248) | GntR family transcriptional regulator |
| M. avium 104 | MAV_0738 | - | 3e-82 | 60.15% (266) | mercuric reductase/transcriptional regulator, fusion |
| M. smegmatis MC2 155 | MSMEG_4659 | - | 2e-23 | 34.60% (237) | GntR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_4188 | - | 2e-16 | 29.46% (241) | PUTATIVE transcriptional regulator, GntR family |
| M. ulcerans Agy99 | MUL_3201 | - | 1e-148 | 97.78% (270) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2288 | - | 1e-20 | 30.93% (236) | UbiC transcription regulator-associated domain-containing |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2603|M.gilvum_PYR-GCK ---------MP--LTVELDRSSPVPLYYQLAQAIEAAIRDGELAPGDRFE
MSMEG_4659|M.smegmatis_MC2_155 ---------MTPTLSVELDRSSPVPLYFQVAQVFEKAILDGQLKPGDRFE
Mvan_2288|M.vanbaalenii_PYR-1 -MRVLTVDAAPLAARPDLVGSSDLPAHARIAQWLEALIASGDLIPGDKLP
MMAR_2560|M.marinum_M MTSDEDSPRHDLADADLRVTRGSVPASVQLAELLRTQILERALSPGSRLP
MUL_3201|M.ulcerans_Agy99 MTSDEDSPRHDLADADLRVTRGSVPASVQLAELLRTQILERALSPGSRLP
Mb0816c|M.bovis_AF2122/97 MTSVK----LDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLP
Rv0792c|M.tuberculosis_H37Rv MTSVK----LDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLP
MAV_0738|M.avium_104 MVPDQ----LDLDAADLRISRGSVPASTQLAEALKAAIVKQRLPRGARLP
TH_4188|M.thermoresistible__bu --------------------VRPRPAYQVLRDRLRDDIAAGRYRDGTRLP
MAB_0953|M.abscessus_ATCC_1997 -----------------MEESEGGPVAEDVRRRILSMLAQGTLHPGSRLG
* : : : * ::
Mflv_2603|M.gilvum_PYR-GCK NELALAKRLTLSRPTTRRAIQELVDKGLLVRKRG-VGTQVVQNP--VHRR
MSMEG_4659|M.smegmatis_MC2_155 NELALASRLNLSRPTTRRAIQELVDKGLLVRKRG-VGTQVVQTP--VHRP
Mvan_2288|M.vanbaalenii_PYR-1 PEVEIATSLGVSRMTLRQALSAVEAKGLIDRRRGRFGGNFVAAPRFEFDH
MMAR_2560|M.marinum_M TEQELIARSGVSRSTVRAAVGILEDEGWLVRRQG--LGTFVAEPVKQDLE
MUL_3201|M.ulcerans_Agy99 TEQELIARSGVSRSTVRAAVGILEDEGWLVRRQG--LGTFVAEPVEQDLE
Mb0816c|M.bovis_AF2122/97 SERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQG--LGTFVADPVEQELS
Rv0792c|M.tuberculosis_H37Rv SERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQG--LGTFVADPVEQELS
MAV_0738|M.avium_104 TERELVDRTRVSRVTVRAAVGLLERQGWLVRRQG--LGTFVANPVKQELG
TH_4188|M.thermoresistible__bu TESELMAQYGVSRQTVRRAFQDLVAEGSVYRVPG--RGTYAADRYLRQFG
MAB_0953|M.abscessus_ATCC_1997 SEREMAERFAVSRATVRSALVPLSRAGILERQTGRGGGTFVRADVVQRNV
* : :** * * *. : * : * * .
Mflv_2603|M.gilvum_PYR-GCK VELTSLFDDLARAGQEPTTRLLKYHIGPPDEDVARELNLAEGREVASIQR
MSMEG_4659|M.smegmatis_MC2_155 VELTSLYDDLARAGQEPATEVLEYTRRPAQADIAERLSIEPGSEIAYMRR
Mvan_2288|M.vanbaalenii_PYR-1 ASLPGFTEQMRRFEVEAGAQVLMATTGRPDAEVSRALGLRRTDQVHRILR
MMAR_2560|M.marinum_M SGVRTITEVLLSRGVTPRVEVLSHAVVAAPQSVGAALGR---SEVLRIQR
MUL_3201|M.ulcerans_Agy99 SGVRTITEVLLSRGVTPRVEVLAHAVVAAPQSVGAALGR---SEVLRIQR
Mb0816c|M.bovis_AF2122/97 CGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGL---VEVLCIRR
Rv0792c|M.tuberculosis_H37Rv CGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGL---VEVLCIRR
MAV_0738|M.avium_104 PGVRTITEVLAASGITPNVDVLSHRVEDAPQRIAETLHL---TKVLCVHR
TH_4188|M.thermoresistible__bu S-----IEDLMALSDDTTMEVRSGLRRRVDVDAASRLRLDD-DVVHTVVF
MAB_0953|M.abscessus_ATCC_1997 AELVGLPTRLHIGGHTSDTRVLGTSRRPATAAERAALEIAEGAEVFDVRR
: . : * : :
Mflv_2603|M.gilvum_PYR-GCK LRCANGEPLALMTNHLP--ADIAP-DAEELGNIGLYQAL-----------
MSMEG_4659|M.smegmatis_MC2_155 LRSSNGQPLALMTNYLP--AALAP-DEDELARSGLYQSL-----------
Mvan_2288|M.vanbaalenii_PYR-1 ARTANGEPIVLEEAYLP--AAVFPGMLSKNLQASLYALM-----------
MMAR_2560|M.marinum_M RYSESDQPLAIVTCYLP--ADLPHDAVEPLLSATSATAT------TYTMW
MUL_3201|M.ulcerans_Agy99 RYSESDQPLAIVTCYLP--TDLPHDAVEPLLSATSVTAT------TYTMW
Mb0816c|M.bovis_AF2122/97 RIRTGDQPLALVTAYLP--PGVG-PAVEPLLSGSADTET------TYAMW
Rv0792c|M.tuberculosis_H37Rv RIRTGDQPLALVTAYLP--PGVG-PAVEPLLSGSADTET------TYAMW
MAV_0738|M.avium_104 RFRDGEQPLALMIAYLP--PGLG-EAVEPLLKSATDTQTGRAMESTYTMW
TH_4188|M.thermoresistible__bu RRLHAGAPFVSTVVHLPDRAAHHLHGCAELRTGAVSTHT------VIGLL
MAB_0953|M.abscessus_ATCC_1997 LRYADGVPLSVDTAYFP--AELVPDLLEQPLGGSLYELC-----------
*: ::* .
Mflv_2603|M.gilvum_PYR-GCK -RARGVHIRLARQRIGARSATRAEAHLLDEKPNAPLLTMARTAFDDSGAA
MSMEG_4659|M.smegmatis_MC2_155 -RARGVHIRLARQRIGAKAADREEARLLDEKPKAPLLVMERTAFDDSGRI
Mvan_2288|M.vanbaalenii_PYR-1 -RGYGHAPCAADERIEATSATPEQARVLGVEPSCPLLLVVRTSFADNGVA
MMAR_2560|M.marinum_M EQRLGVRISSATHEIQAAGASPEIAAALGLSEGAPVLVLRRTSYTDGDKP
MUL_3201|M.ulcerans_Agy99 EQRLGVRISSATHEVQAAGASPEIASALGLSEGAPVLVLRRTSYTDGDKP
Mb0816c|M.bovis_AF2122/97 ERRLGVRIAQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGKP
Rv0792c|M.tuberculosis_H37Rv ERRLGVRIAQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGKP
MAV_0738|M.avium_104 ERRLDTPIARASYEIHAAGASVEVAGALNLPLGSPVLVLERTSYGHDDTP
TH_4188|M.thermoresistible__bu EPHLEEPIDQAAQSITVAPADDDTADAVGVEPGHPMLRIDRLYSDRTGRP
MAB_0953|M.abscessus_ATCC_1997 QVRYGLQADSSTETIEVVSANPREAEWLDVPHRRPLLAITRVTRNTDGRP
: : . * * :. *:* : * .
Mflv_2603|M.gilvum_PYR-GCK VEFGNHCYRASRYYFDTTLVDR----------------------------
MSMEG_4659|M.smegmatis_MC2_155 VEYGSHAYRASRYYFDTTLVDR----------------------------
Mvan_2288|M.vanbaalenii_PYR-1 VEFSRDYHRSDRTTIRIQSRADPVRQGY----------------------
MMAR_2560|M.marinum_M LEVVLFHHRPERYEFCVTLPRTMPGQRAGMTER-----------------
MUL_3201|M.ulcerans_Agy99 LEVVLFHHRPERYEFCVTLPRTMPGQRAGMTER-----------------
Mb0816c|M.bovis_AF2122/97 LEVVVFHHRPERYQFSVTLPRTLPGSGAGIIEKRDFA-------------
Rv0792c|M.tuberculosis_H37Rv LEVVVFHHRPERYQFSVTLPRTLPGSGAGIIEKRDFA-------------
MAV_0738|M.avium_104 LEVVEFHYRPERYRFSVTLPRTVPGPGAGIVERSG---------------
TH_4188|M.thermoresistible__bu VELSVSHFLPEQYTYRVTLRRE----------------------------
MAB_0953|M.abscessus_ATCC_1997 FEFSYDLFRADRVRLTATMTSAVAQESRGVDGKVERVVSRLAAHRRPDDT
.* . ..:
Mflv_2603|M.gilvum_PYR-GCK ---
MSMEG_4659|M.smegmatis_MC2_155 ---
Mvan_2288|M.vanbaalenii_PYR-1 ---
MMAR_2560|M.marinum_M ---
MUL_3201|M.ulcerans_Agy99 ---
Mb0816c|M.bovis_AF2122/97 ---
Rv0792c|M.tuberculosis_H37Rv ---
MAV_0738|M.avium_104 ---
TH_4188|M.thermoresistible__bu ---
MAB_0953|M.abscessus_ATCC_1997 LLA