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M. smegmatis MC2 155 MSMEG_4659 (-)

annotation: GntR-family protein transcriptional regulator
coordinates: 4746349 - 4747086
length: 245

TPTLSVELDRSSPVPLYFQVAQVFEKAILDGQLKPGDRFENELALASRLNLSRPTTRRAIQELVDKGLLV
RKRGVGTQVVQTPVHRPVELTSLYDDLARAGQEPATEVLEYTRRPAQADIAERLSIEPGSEIAYMRRLRS
SNGQPLALMTNYLPAALAPDEDELARSGLYQSLRARGVHIRLARQRIGAKAADREEARLLDEKPKAPLLV
MERTAFDDSGRIVEYGSHAYRASRYYFDTTLVDR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_4659--100% (245)GntR-family protein transcriptional regulator
M. smegmatis MC2 155MSMEG_0778-6e-2032.77% (238) putative transcriptional regulator
M. smegmatis MC2 155MSMEG_0286-2e-1829.38% (211) GntR-family protein transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0816c-6e-2231.78% (236) GntR family transcriptional regulator
M. gilvum PYR-GCKMflv_2603-1e-10074.69% (241) UbiC transcription regulator-associated domain-containing
M. tuberculosis H37RvRv0792c-6e-2231.78% (236) GntR family transcriptional regulator
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0953-2e-2334.31% (239) GntR family transcriptional regulator
M. marinum MMMAR_2560-2e-2334.60% (237) GntR family transcriptional regulator
M. avium 104MAV_0738-4e-1830.99% (242) mercuric reductase/transcriptional regulator, fusion
M. thermoresistible (build 8)TH_3932-5e-1628.10% (242) PUTATIVE transcriptional regulator, GntR family
M. ulcerans Agy99MUL_0525-5e-2427.42% (248) transcriptional regulatory protein
M. vanbaalenii PYR-1Mvan_4015-1e-10075.52% (241) UbiC transcription regulator-associated domain-containing

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2603|M.gilvum_PYR-GCK          ----------MP--LTVELDRSSPVPLYYQLAQAIEAAIRDGELAPGDRF
Mvan_4015|M.vanbaalenii_PYR-1       ----------MP--LTVELDRSSPVPLYYQLAQAIEAAIRGGELAPGDRF
MSMEG_4659|M.smegmatis_MC2_155      ----------MTPTLSVELDRSSPVPLYFQVAQVFEKAILDGQLKPGDRF
Mb0816c|M.bovis_AF2122/97           MTSVK----LDLDAADLRISRGS-VPASTQLAEALKAQIIQQRLPRGGRL
Rv0792c|M.tuberculosis_H37Rv        MTSVK----LDLDAADLRISRGS-VPASTQLAEALKAQIIQQRLPRGGRL
MAV_0738|M.avium_104                MVPDQ----LDLDAADLRISRGS-VPASTQLAEALKAAIVKQRLPRGARL
MMAR_2560|M.marinum_M               MTSDEDSPRHDLADADLRVTRGS-VPASVQLAELLRTQILERALSPGSRL
MAB_0953|M.abscessus_ATCC_1997      ------------------MEESEGGPVAEDVRRRILSMLAQGTLHPGSRL
TH_3932|M.thermoresistible__bu      ------MTRTATPMRSTTINRFADRPLYRQLSEVLEARLIERAR-PGDRL
MUL_0525|M.ulcerans_Agy99           -------MEGSQVLQLGQIDRADDKPPYRQIASMLRGAIISGELEAGGRL
                                                      : .    *   ::   :   :       * *:

Mflv_2603|M.gilvum_PYR-GCK          ENELALAKRLTLSRPTTRRAIQELVDKGLLVRKRGVG--TQVVQNPVHRR
Mvan_4015|M.vanbaalenii_PYR-1       ENELALAKRLTLSRPTTRRAIQELVDKGLLVRKRGVG--TQVVQNPVHRR
MSMEG_4659|M.smegmatis_MC2_155      ENELALASRLNLSRPTTRRAIQELVDKGLLVRKRGVG--TQVVQTPVHRP
Mb0816c|M.bovis_AF2122/97           PSERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQGLG--TFVADPVEQEL
Rv0792c|M.tuberculosis_H37Rv        PSERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQGLG--TFVADPVEQEL
MAV_0738|M.avium_104                PTERELVDRTRVSRVTVRAAVGLLERQGWLVRRQGLG--TFVANPVKQEL
MMAR_2560|M.marinum_M               PTEQELIARSGVSRSTVRAAVGILEDEGWLVRRQGLG--TFVAEPVKQDL
MAB_0953|M.abscessus_ATCC_1997      GSEREMAERFAVSRATVRSALVPLSRAGILERQTGRGGGTFVRADVVQRN
TH_3932|M.thermoresistible__bu      PSEAELSGQFGVNRLTVRRALHELAQRGIIETVHGRG--SFVARQPVRYR
MUL_0525|M.ulcerans_Agy99           PSEAELIEYFGVARMTVRQAVQELRTEGLVISEHGRG--VFVRPAPPIRW
                                     .*  :     : * *.* *:  *   * :    * *    *        

Mflv_2603|M.gilvum_PYR-GCK          ------------VELTSLFDDLARAGQEPTTRLLKYHIGPPDEDVARELN
Mvan_4015|M.vanbaalenii_PYR-1       ------------VELTSLFDDLARAGQEPTTRLLEYHVGPPDEDVARELN
MSMEG_4659|M.smegmatis_MC2_155      ------------VELTSLYDDLARAGQEPATEVLEYTRRPAQADIAERLS
Mb0816c|M.bovis_AF2122/97           S-----------CGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLG
Rv0792c|M.tuberculosis_H37Rv        S-----------CGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLG
MAV_0738|M.avium_104                G-----------PGVRTITEVLAASGITPNVDVLSHRVEDAPQRIAETLH
MMAR_2560|M.marinum_M               E-----------SGVRTITEVLLSRGVTPRVEVLSHAVVAAPQSVGAALG
MAB_0953|M.abscessus_ATCC_1997      V-----------AELVGLPTRLHIGGHTSDTRVLGTSRRPATAAERAALE
TH_3932|M.thermoresistible__bu      LS---------ATRDASFTRGMRELGHPVRIEVLGAETTRCR-RLRTELH
MUL_0525|M.ulcerans_Agy99           LASDRFARQHRANGKAAFTVEAERSGHTPQVDNITVSREKPDSVVAERLR
                                                     :       *       :              * 

Mflv_2603|M.gilvum_PYR-GCK          LAEGREVASIQRLRCANGEPLALMTNHLPADIAPDAEELGNIGLYQALR-
Mvan_4015|M.vanbaalenii_PYR-1       LAEGRDVASIRRLRCANGEPLALMTNYLPAEIAPDAEELESNGLYQSLR-
MSMEG_4659|M.smegmatis_MC2_155      IEPGSEIAYMRRLRSSNGQPLALMTNYLPAALAPDEDELARSGLYQSLR-
Mb0816c|M.bovis_AF2122/97           LV---EVLCIRRRIRTGDQPLALVTAYLPPGVG-PAVEPLLSGSADTET-
Rv0792c|M.tuberculosis_H37Rv        LV---EVLCIRRRIRTGDQPLALVTAYLPPGVG-PAVEPLLSGSADTET-
MAV_0738|M.avium_104                LT---KVLCVHRRFRDGEQPLALMIAYLPPGLG-EAVEPLLKSATDTQTG
MMAR_2560|M.marinum_M               RS---EVLRIQRRYSESDQPLAIVTCYLPADLPHDAVEPLLSATSATAT-
MAB_0953|M.abscessus_ATCC_1997      IAEGAEVFDVRRLRYADGVPLSVDTAYFPAELVPDLLEQPLGGSLYELC-
TH_3932|M.thermoresistible__bu      TAG--EVLTTTTLRHVDGQPWSVSVTSIALDRFPGIAQQWSGSTSLFDF-
MUL_0525|M.ulcerans_Agy99           LTADDEVVVRSRRYLADGKPVETATSYIPVAFAQGTKIEQTDTGPGGIYA
                                         .:         .  *       :.                     

Mflv_2603|M.gilvum_PYR-GCK          ------------ARGVHIRLARQRIGARSATRAEAHLLDEKPNAPLLTMA
Mvan_4015|M.vanbaalenii_PYR-1       ------------ARGVHIRLARQRIGARSATRAEASLLDEKPNAPLLTMA
MSMEG_4659|M.smegmatis_MC2_155      ------------ARGVHIRLARQRIGAKAADREEARLLDEKPKAPLLVME
Mb0816c|M.bovis_AF2122/97           -----TYAMWERRLGVRIAQATHEIHAAGASPDVADALGLAVGSPVLVVD
Rv0792c|M.tuberculosis_H37Rv        -----TYAMWERRLGVRIAQATHEIHAAGASPDVADALGLAVGSPVLVVD
MAV_0738|M.avium_104                RAMESTYTMWERRLDTPIARASYEIHAAGASVEVAGALNLPLGSPVLVLE
MMAR_2560|M.marinum_M               -----TYTMWEQRLGVRISSATHEIQAAGASPEIAAALGLSEGAPVLVLR
MAB_0953|M.abscessus_ATCC_1997      ----------QVRYGLQADSSTETIEVVSANPREAEWLDVPHRRPLLAIT
TH_3932|M.thermoresistible__bu      ---------LWQTFGVRMRRAYRSFSAVLADLAEAQHLGLRTGAPVLEMR
MUL_0525|M.ulcerans_Agy99           R---------FEEAGHTLARFNEEVGARMPTPEERRALQLPPGAPVLTVV
                                                  .         . .  .       *      *:* : 

Mflv_2603|M.gilvum_PYR-GCK          RTAFDDSGAAVEFGNHCYRASRYYFDTTLVDR------------------
Mvan_4015|M.vanbaalenii_PYR-1       RTAFDDSGAAVEFGNHCYRASRYYFDTTLVDR------------------
MSMEG_4659|M.smegmatis_MC2_155      RTAFDDSGRIVEYGSHAYRASRYYFDTTLVDR------------------
Mb0816c|M.bovis_AF2122/97           RTSYTNDGKPLEVVVFHHRPERYQFSVTLPRTLPGSGAGIIEKRDFA---
Rv0792c|M.tuberculosis_H37Rv        RTSYTNDGKPLEVVVFHHRPERYQFSVTLPRTLPGSGAGIIEKRDFA---
MAV_0738|M.avium_104                RTSYGHDDTPLEVVEFHYRPERYRFSVTLPRTVPGPGAGIVERSG-----
MMAR_2560|M.marinum_M               RTSYTDGDKPLEVVLFHHRPERYEFCVTLPRTMPGQRAGMTER-------
MAB_0953|M.abscessus_ATCC_1997      RVTRNTDGRPFEFSYDLFRADRVRLTATMTSAVAQESRGVDGKVERVVSR
TH_3932|M.thermoresistible__bu      GLNVDQHGAPVAVVRHRFRGDRVELTVDLA--------------------
MUL_0525|M.ulcerans_Agy99           RTAYDTKDVAVEVCDTVKVASAYLLEYDFSAR------------------
                                           .  .         .   :   :                     

Mflv_2603|M.gilvum_PYR-GCK          -------------
Mvan_4015|M.vanbaalenii_PYR-1       -------------
MSMEG_4659|M.smegmatis_MC2_155      -------------
Mb0816c|M.bovis_AF2122/97           -------------
Rv0792c|M.tuberculosis_H37Rv        -------------
MAV_0738|M.avium_104                -------------
MMAR_2560|M.marinum_M               -------------
MAB_0953|M.abscessus_ATCC_1997      LAAHRRPDDTLLA
TH_3932|M.thermoresistible__bu      -------------
MUL_0525|M.ulcerans_Agy99           -------------