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LVEPMNQSSVFQPPDRQRVDERIATTIADAILDGVFPPGSTLPPERDLAERLGVNRTSLRQGLARLQQMG LIEVRHGSGSVVRDPEGLTHPAVVEALVRKLGPDFLVELLEIRAALGPLIGRLAAARSTPEDAEALCAAL EVVQQADTAAARQAADLAYFRVLIHSTRNRALGLLYRWVEHAFGGREHALTGAYDDADPVLTDLRAINGA VLAGDPAAAAATVEAYLNASALRMVKSYRDRA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0494 | - | - | 100% (242) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY GNTR-FAMILY) |
| M. tuberculosis H37Rv | Rv0586 | - | 2e-21 | 31.80% (239) | GntR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0792c | - | 3e-06 | 34.38% (64) | GntR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0505 | - | 1e-134 | 100.00% (242) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0016 | - | 5e-15 | 29.03% (217) | GntR domain-containing protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3018 | - | 7e-21 | 31.46% (213) | GntR family transcriptional regulator |
| M. marinum M | MMAR_0820 | - | 1e-108 | 83.83% (235) | GntR family transcriptional regulator |
| M. avium 104 | MAV_2542 | - | 2e-09 | 28.09% (178) | regulatory protein GntR, HTH |
| M. smegmatis MC2 155 | MSMEG_3527 | - | 2e-16 | 29.91% (224) | putative HTH-type transcriptional regulator |
| M. thermoresistible (build 8) | TH_1959 | - | 5e-19 | 29.58% (240) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (GNTR-FAMILY) |
| M. ulcerans Agy99 | MUL_4564 | - | 1e-108 | 83.83% (235) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2942 | - | 1e-21 | 34.51% (226) | regulatory protein GntR, HTH |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0494|M.tuberculosis_H37Rv -----MVEPMNQSSVFQPPDRQRVDERIATTIADAILDGVFPPGSTLPPE
Mb0505|M.bovis_AF2122/97 -----MVEPMNQSSVFQPPDRQRVDERIATTIADAILDGVFPPGSTLPPE
MMAR_0820|M.marinum_M ---------MNQSSILQPPDRQRVDEQIATSIADAILDGVFPPGSALPPE
MUL_4564|M.ulcerans_Agy99 ---------MNQSSILQPPDRQRVDEQIATSIADAILDGVFPPGSALPPE
TH_1959|M.thermoresistible__bu -------------MALQPVNRRSVPEDVFDQIVGEVLSGQMQPGDALPSE
Mvan_2942|M.vanbaalenii_PYR-1 -------------MALRPVNRRSVPEDVFDQIISDVLSGEMRPGETLPSE
MSMEG_3527|M.smegmatis_MC2_155 ----------MAVMALQPVNRRSVPEDVFEQIVSEVLTGEMRPGESLPSE
MAB_3018|M.abscessus_ATCC_1997 -------------MALQPIARQSIPDEIFSQLAAQVLTGDRIPGDTLPSE
Mflv_0016|M.gilvum_PYR-GCK -----MIGRKDIRVPLSTARRSGLVEQVIDQLRHAVAGQEWRIGDRIPNE
MAV_2542|M.avium_104 MPKREPLAPMATSQNNGAVRSPKTAEIVADTLRRMIVEGQLKDGDFLPYE
. : : : : *. :* *
Rv0494|M.tuberculosis_H37Rv RDLAERLGVNRTSLRQGLARLQQMGLIEVRHGS--GSVVRDPEGLTHPAV
Mb0505|M.bovis_AF2122/97 RDLAERLGVNRTSLRQGLARLQQMGLIEVRHGS--GSVVRDPEGLTHPAV
MMAR_0820|M.marinum_M RELAEQLGVNRTSLRQGLARLQQMGLIETRQGS--GNVVRDPQSLTHPAV
MUL_4564|M.ulcerans_Agy99 RELAEQLGVNRTSLRQGLARLQQMGLIETRQGS--GNVVRDPQSLTHPAV
TH_1959|M.thermoresistible__bu RRLAEVLGVSRPAVREALKRLSAAGLVEVRQGE--ITTVRDYRRHAGLDL
Mvan_2942|M.vanbaalenii_PYR-1 RRLAEVLGVSRPAIREALKRLAAAGLIEVRQGD--ATTVRDFRRTAGLDL
MSMEG_3527|M.smegmatis_MC2_155 RRLAEVLGVSRPAVREAIKRLTAAGLVEVRQGD--ATTVRDFRRHAGMDL
MAB_3018|M.abscessus_ATCC_1997 RALAEALGVSRAAVREALGRLERSGLIQIRQGG--STVIRDYRSDAGFDV
Mflv_0016|M.gilvum_PYR-GCK TVLVEKFGVGRNTVREAVRALAHAGILEVRQGD--GTYVR-----ATSEV
MAV_2542|M.avium_104 AELMDHFQVSRPSLREAVRVLESDRLVEVRRGSRTGARVRVPGPEIVARP
* : : *.* ::*:.: * ::: *:* :*
Rv0494|M.tuberculosis_H37Rv VEALVRKLG---PDFLVELLEIRAALGPLIGRLAAAR--STPEDAEALCA
Mb0505|M.bovis_AF2122/97 VEALVRKLG---PDFLVELLEIRAALGPLIGRLAAAR--STPEDAEALCA
MMAR_0820|M.marinum_M VEALVRKLG---PDFLVEVLEIRAALGPLIGRLAAER--NSSEDAEALRA
MUL_4564|M.ulcerans_Agy99 VEALVRKLG---PDFLVEVLEIRAALGPLIGRLAAER--NSSEDAEALRA
TH_1959|M.thermoresistible__bu LPRLLFRAGELDVTVVRSILETRLHNGPKVAELAARR--RPPGLGALLDE
Mvan_2942|M.vanbaalenii_PYR-1 LPRLLIRDGDLDLAVVRSILETRLHNGPKVAELAAQR--RGPELSDELNT
MSMEG_3527|M.smegmatis_MC2_155 LPRLLFRAGELDTSVVRSILETRLHNGPKVAELAAER--RGAELVGQLTA
MAB_3018|M.abscessus_ATCC_1997 LPLLLAYGGDVDRRTLASVIEARAIIGPQVARLAAQRAHQTPGVADRLRA
Mflv_0016|M.gilvum_PYR-GCK SGALRRLCG----EELREVLEVRRALEVEAARLAASR--RTPADVAEMRG
MAV_2542|M.avium_104 AGFLLEMAG----TTLADVMTARMGIEPYAARLLAED--GTAAAHRELRE
* * : .:: * ..* * . :
Rv0494|M.tuberculosis_H37Rv ALEVVQQADTA---AARQAADLAYFRVLIHSTRNRALGLLYRWVEHAFGG
Mb0505|M.bovis_AF2122/97 ALEVVQQADTA---AARQAADLAYFRVLIHSTRNRALGLLYRWVEHAFGG
MMAR_0820|M.marinum_M ALAEVADADTA---PARQAADLAYFRVLIHGTRNRALGLLYRWVEQAFGG
MUL_4564|M.ulcerans_Agy99 ALAEVADADTA---PARQAADLAYFRVLIHGTRNRALGLLYRWVEQAFGG
TH_1959|M.thermoresistible__bu AVQTLAAETDP---VERQRHALRFWDHVVDGADSIAFRLMYNTLRATYEP
Mvan_2942|M.vanbaalenii_PYR-1 AMRALADEADP---VAAQRHALDFWDHIVDGADSIAFRLMFNTLRATYEP
MSMEG_3527|M.smegmatis_MC2_155 VVHALEAEIDP---IQRQRHAMTFWDHVVDGADSIAFRLMFNTLRETYEP
MAB_3018|M.abscessus_ATCC_1997 MTSELEAEDDP---LQRMWQALGFWELVIDTADSIAFRLVFNTMRDSYVR
Mflv_0016|M.gilvum_PYR-GCK LLARRDERDSAGDVEAFARIDTEFHLAVVRCARNNTLIELYRGLLEAVTA
MAV_2542|M.avium_104 LIEEIPAAWETG---KLGAASTALHRRLVELSGNATLTVIVGMLHEIFER
. :: : . :: : :
Rv0494|M.tuberculosis_H37Rv REHALTGAYDDADPVLT------DLRAINGAVLAGDPAAAAATVEAYLNA
Mb0505|M.bovis_AF2122/97 REHALTGAYDDADPVLT------DLRAINGAVLAGDPAAAAATVEAYLNA
MMAR_0820|M.marinum_M REHELTGAYEDADPVIA------DLTAINDAVLAGDPETAAAAVEGYLNA
MUL_4564|M.ulcerans_Agy99 REHDLTGAYEDADPVIA------DLTAINDAVLAGDPETAAAAVEGYLNA
TH_1959|M.thermoresistible__bu ALPALATMMAAEVGRPQ------AYRALAAAIEAGDPTAAEQSARDLLEP
Mvan_2942|M.vanbaalenii_PYR-1 ALPALATMMAAEVGRVD------AYRAVAEAVLAGDPAAARDNAHRLLEP
MSMEG_3527|M.smegmatis_MC2_155 VLPALAAVMAGEVADPD------AYRAITRAISDRDADAARGAAQNLLEP
MAB_3018|M.abscessus_ATCC_1997 ALDVLVNVMAAEVGDIG------HYRALADAIALADPDAAQDAAAGMLAL
Mflv_0016|M.gilvum_PYR-GCK S----VAHTRHVPVDVC------DHGVLLDHIAAGDPDLAARTAGEFLDR
MAV_2542|M.avium_104 HMTAAFLSVQNVVPKAQYNKLMRSYTRLADLVAARDGAEAEAHWRRHMEN
: : * * :
Rv0494|M.tuberculosis_H37Rv SALRMVKSYRDRA-------
Mb0505|M.bovis_AF2122/97 SALRMVKSYRDRA-------
MMAR_0820|M.marinum_M SALRMIMCYRAAYAGEDPER
MUL_4564|M.ulcerans_Agy99 SALRMIMCYRAAYAGEDPER
TH_1959|M.thermoresistible__bu ATAALLSALDELEAQK----
Mvan_2942|M.vanbaalenii_PYR-1 ATTALLDALHTLEEPR----
MSMEG_3527|M.smegmatis_MC2_155 ATHALLGALDALEAAR----
MAB_3018|M.abscessus_ATCC_1997 GTKAFDKLLREMEKER----
Mflv_0016|M.gilvum_PYR-GCK IINGLGSADSS---------
MAV_2542|M.avium_104 ASAELLKGHEKTKVRDIMH-
: