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VPLTVELDRSSPVPLYYQLAQAIEAAIRDGELAPGDRFENELALAKRLTLSRPTTRRAIQELVDKGLLVR KRGVGTQVVQNPVHRRVELTSLFDDLARAGQEPTTRLLKYHIGPPDEDVARELNLAEGREVASIQRLRCA NGEPLALMTNHLPADIAPDAEELGNIGLYQALRARGVHIRLARQRIGARSATRAEAHLLDEKPNAPLLTM ARTAFDDSGAAVEFGNHCYRASRYYFDTTLVDR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2603 | - | - | 100% (243) | UbiC transcription regulator-associated domain-containing protein |
| M. gilvum PYR-GCK | Mflv_1234 | - | 4e-19 | 32.76% (232) | UbiC transcription regulator-associated domain-containing |
| M. gilvum PYR-GCK | Mflv_2652 | - | 2e-18 | 29.82% (228) | regulatory protein GntR, HTH |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0816c | - | 1e-20 | 32.20% (236) | GntR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0792c | - | 1e-20 | 32.20% (236) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0953 | - | 1e-22 | 33.33% (240) | GntR family transcriptional regulator |
| M. marinum M | MMAR_2560 | - | 1e-20 | 32.49% (237) | GntR family transcriptional regulator |
| M. avium 104 | MAV_0738 | - | 4e-16 | 28.63% (262) | mercuric reductase/transcriptional regulator, fusion |
| M. smegmatis MC2 155 | MSMEG_4659 | - | 1e-100 | 74.69% (241) | GntR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3932 | - | 4e-16 | 28.45% (232) | PUTATIVE transcriptional regulator, GntR family |
| M. ulcerans Agy99 | MUL_0525 | - | 5e-23 | 29.44% (248) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4015 | - | 1e-129 | 95.06% (243) | UbiC transcription regulator-associated domain-containing |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2603|M.gilvum_PYR-GCK ----------MP--LTVELDRSSPVPLYYQLAQAIEAAIRDGELAPGDRF
Mvan_4015|M.vanbaalenii_PYR-1 ----------MP--LTVELDRSSPVPLYYQLAQAIEAAIRGGELAPGDRF
MSMEG_4659|M.smegmatis_MC2_155 ----------MTPTLSVELDRSSPVPLYFQVAQVFEKAILDGQLKPGDRF
Mb0816c|M.bovis_AF2122/97 MTSVK----LDLDAADLRISRGS-VPASTQLAEALKAQIIQQRLPRGGRL
Rv0792c|M.tuberculosis_H37Rv MTSVK----LDLDAADLRISRGS-VPASTQLAEALKAQIIQQRLPRGGRL
MAV_0738|M.avium_104 MVPDQ----LDLDAADLRISRGS-VPASTQLAEALKAAIVKQRLPRGARL
MMAR_2560|M.marinum_M MTSDEDSPRHDLADADLRVTRGS-VPASVQLAELLRTQILERALSPGSRL
MAB_0953|M.abscessus_ATCC_1997 ------------------MEESEGGPVAEDVRRRILSMLAQGTLHPGSRL
TH_3932|M.thermoresistible__bu ------MTRTATPMRSTTINRFADRPLYRQLSEVLEARLIERAR-PGDRL
MUL_0525|M.ulcerans_Agy99 -------MEGSQVLQLGQIDRADDKPPYRQIASMLRGAIISGELEAGGRL
: . * :: : : * *:
Mflv_2603|M.gilvum_PYR-GCK ENELALAKRLTLSRPTTRRAIQELVDKGLLVRKRGVG--TQVVQNPVHRR
Mvan_4015|M.vanbaalenii_PYR-1 ENELALAKRLTLSRPTTRRAIQELVDKGLLVRKRGVG--TQVVQNPVHRR
MSMEG_4659|M.smegmatis_MC2_155 ENELALASRLNLSRPTTRRAIQELVDKGLLVRKRGVG--TQVVQTPVHRP
Mb0816c|M.bovis_AF2122/97 PSERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQGLG--TFVADPVEQEL
Rv0792c|M.tuberculosis_H37Rv PSERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQGLG--TFVADPVEQEL
MAV_0738|M.avium_104 PTERELVDRTRVSRVTVRAAVGLLERQGWLVRRQGLG--TFVANPVKQEL
MMAR_2560|M.marinum_M PTEQELIARSGVSRSTVRAAVGILEDEGWLVRRQGLG--TFVAEPVKQDL
MAB_0953|M.abscessus_ATCC_1997 GSEREMAERFAVSRATVRSALVPLSRAGILERQTGRGGGTFVRADVVQRN
TH_3932|M.thermoresistible__bu PSEAELSGQFGVNRLTVRRALHELAQRGIIETVHGRG--SFVARQPVRYR
MUL_0525|M.ulcerans_Agy99 PSEAELIEYFGVARMTVRQAVQELRTEGLVISEHGRG--VFVRPAPPIRW
.* : : * *.* *: * * : * * *
Mflv_2603|M.gilvum_PYR-GCK ------------VELTSLFDDLARAGQEPTTRLLKYHIGPPDEDVARELN
Mvan_4015|M.vanbaalenii_PYR-1 ------------VELTSLFDDLARAGQEPTTRLLEYHVGPPDEDVARELN
MSMEG_4659|M.smegmatis_MC2_155 ------------VELTSLYDDLARAGQEPATEVLEYTRRPAQADIAERLS
Mb0816c|M.bovis_AF2122/97 S-----------CGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLG
Rv0792c|M.tuberculosis_H37Rv S-----------CGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLG
MAV_0738|M.avium_104 G-----------PGVRTITEVLAASGITPNVDVLSHRVEDAPQRIAETLH
MMAR_2560|M.marinum_M E-----------SGVRTITEVLLSRGVTPRVEVLSHAVVAAPQSVGAALG
MAB_0953|M.abscessus_ATCC_1997 V-----------AELVGLPTRLHIGGHTSDTRVLGTSRRPATAAERAALE
TH_3932|M.thermoresistible__bu LS---------ATRDASFTRGMRELGHPVRIEVLGAETTRCR-RLRTELH
MUL_0525|M.ulcerans_Agy99 LASDRFARQHRANGKAAFTVEAERSGHTPQVDNITVSREKPDSVVAERLR
: * : *
Mflv_2603|M.gilvum_PYR-GCK LAEGREVASIQRLRCANGEPLALMTNHLPADIAPDAEELGNIGLYQALR-
Mvan_4015|M.vanbaalenii_PYR-1 LAEGRDVASIRRLRCANGEPLALMTNYLPAEIAPDAEELESNGLYQSLR-
MSMEG_4659|M.smegmatis_MC2_155 IEPGSEIAYMRRLRSSNGQPLALMTNYLPAALAPDEDELARSGLYQSLR-
Mb0816c|M.bovis_AF2122/97 LV---EVLCIRRRIRTGDQPLALVTAYLPPGVG-PAVEPLLSGSADTET-
Rv0792c|M.tuberculosis_H37Rv LV---EVLCIRRRIRTGDQPLALVTAYLPPGVG-PAVEPLLSGSADTET-
MAV_0738|M.avium_104 LT---KVLCVHRRFRDGEQPLALMIAYLPPGLG-EAVEPLLKSATDTQTG
MMAR_2560|M.marinum_M RS---EVLRIQRRYSESDQPLAIVTCYLPADLPHDAVEPLLSATSATAT-
MAB_0953|M.abscessus_ATCC_1997 IAEGAEVFDVRRLRYADGVPLSVDTAYFPAELVPDLLEQPLGGSLYELC-
TH_3932|M.thermoresistible__bu TAG--EVLTTTTLRHVDGQPWSVSVTSIALDRFPGIAQQWSGSTSLFDF-
MUL_0525|M.ulcerans_Agy99 LTADDEVVVRSRRYLADGKPVETATSYIPVAFAQGTKIEQTDTGPGGIYA
.: . * :.
Mflv_2603|M.gilvum_PYR-GCK ------------ARGVHIRLARQRIGARSATRAEAHLLDEKPNAPLLTMA
Mvan_4015|M.vanbaalenii_PYR-1 ------------ARGVHIRLARQRIGARSATRAEASLLDEKPNAPLLTMA
MSMEG_4659|M.smegmatis_MC2_155 ------------ARGVHIRLARQRIGAKAADREEARLLDEKPKAPLLVME
Mb0816c|M.bovis_AF2122/97 -----TYAMWERRLGVRIAQATHEIHAAGASPDVADALGLAVGSPVLVVD
Rv0792c|M.tuberculosis_H37Rv -----TYAMWERRLGVRIAQATHEIHAAGASPDVADALGLAVGSPVLVVD
MAV_0738|M.avium_104 RAMESTYTMWERRLDTPIARASYEIHAAGASVEVAGALNLPLGSPVLVLE
MMAR_2560|M.marinum_M -----TYTMWEQRLGVRISSATHEIQAAGASPEIAAALGLSEGAPVLVLR
MAB_0953|M.abscessus_ATCC_1997 ----------QVRYGLQADSSTETIEVVSANPREAEWLDVPHRRPLLAIT
TH_3932|M.thermoresistible__bu ---------LWQTFGVRMRRAYRSFSAVLADLAEAQHLGLRTGAPVLEMR
MUL_0525|M.ulcerans_Agy99 R---------FEEAGHTLARFNEEVGARMPTPEERRALQLPPGAPVLTVV
. . . . * *:* :
Mflv_2603|M.gilvum_PYR-GCK RTAFDDSGAAVEFGNHCYRASRYYFDTTLVDR------------------
Mvan_4015|M.vanbaalenii_PYR-1 RTAFDDSGAAVEFGNHCYRASRYYFDTTLVDR------------------
MSMEG_4659|M.smegmatis_MC2_155 RTAFDDSGRIVEYGSHAYRASRYYFDTTLVDR------------------
Mb0816c|M.bovis_AF2122/97 RTSYTNDGKPLEVVVFHHRPERYQFSVTLPRTLPGSGAGIIEKRDFA---
Rv0792c|M.tuberculosis_H37Rv RTSYTNDGKPLEVVVFHHRPERYQFSVTLPRTLPGSGAGIIEKRDFA---
MAV_0738|M.avium_104 RTSYGHDDTPLEVVEFHYRPERYRFSVTLPRTVPGPGAGIVERSG-----
MMAR_2560|M.marinum_M RTSYTDGDKPLEVVLFHHRPERYEFCVTLPRTMPGQRAGMTER-------
MAB_0953|M.abscessus_ATCC_1997 RVTRNTDGRPFEFSYDLFRADRVRLTATMTSAVAQESRGVDGKVERVVSR
TH_3932|M.thermoresistible__bu GLNVDQHGAPVAVVRHRFRGDRVELTVDLA--------------------
MUL_0525|M.ulcerans_Agy99 RTAYDTKDVAVEVCDTVKVASAYLLEYDFSAR------------------
. . . : :
Mflv_2603|M.gilvum_PYR-GCK -------------
Mvan_4015|M.vanbaalenii_PYR-1 -------------
MSMEG_4659|M.smegmatis_MC2_155 -------------
Mb0816c|M.bovis_AF2122/97 -------------
Rv0792c|M.tuberculosis_H37Rv -------------
MAV_0738|M.avium_104 -------------
MMAR_2560|M.marinum_M -------------
MAB_0953|M.abscessus_ATCC_1997 LAAHRRPDDTLLA
TH_3932|M.thermoresistible__bu -------------
MUL_0525|M.ulcerans_Agy99 -------------