For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_4188 (-)

annotation: transcriptional regulator, GntR family
coordinates: 356681 - 357397
length: 239

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4188--100% (239)transcriptional regulator, GntR family
M. thermoresistible (build 8)TH_0099-2e-1325.54% (231) transcriptional regulator, GntR family protein
M. thermoresistible (build 8)TH_3932-3e-1228.46% (246) PUTATIVE transcriptional regulator, GntR family

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0816c-1e-2032.51% (243) GntR family transcriptional regulator
M. gilvum PYR-GCKMflv_0447-2e-9575.42% (236) regulatory protein GntR, HTH
M. tuberculosis H37RvRv0792c-1e-2032.51% (243) GntR family transcriptional regulator
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2239-3e-1230.36% (247) GntR family transcriptional regulator
M. marinum MMMAR_2560-3e-1629.46% (241) GntR family transcriptional regulator
M. avium 104MAV_0738-1e-1630.40% (250) mercuric reductase/transcriptional regulator, fusion
M. smegmatis MC2 155MSMEG_5630-7e-1626.84% (231) transcriptional regulator, GntR family protein
M. ulcerans Agy99MUL_3201-2e-1629.46% (241) GntR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_0220-2e-9374.15% (236) regulatory protein GntR, HTH

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0447|M.gilvum_PYR-GCK          ---------------------MP-PAYQVLRERLRDEIAAGCYPDGTRLP
Mvan_0220|M.vanbaalenii_PYR-1       ---------------------MP-PAYQVLRERLRDDIAAGRYPDGTRLP
TH_4188|M.thermoresistible__bu      --------------------VRPRPAYQVLRDRLRDDIAAGRYRDGTRLP
Mb0816c|M.bovis_AF2122/97           MTSVK----LDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLP
Rv0792c|M.tuberculosis_H37Rv        MTSVK----LDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLP
MAV_0738|M.avium_104                MVPDQ----LDLDAADLRISRGSVPASTQLAEALKAAIVKQRLPRGARLP
MMAR_2560|M.marinum_M               MTSDEDSPRHDLADADLRVTRGSVPASVQLAELLRTQILERALSPGSRLP
MUL_3201|M.ulcerans_Agy99           MTSDEDSPRHDLADADLRVTRGSVPASVQLAELLRTQILERALSPGSRLP
MAB_2239|M.abscessus_ATCC_1997      ----------MAAAEPTPLRRPRADQARLVADVLRHQIHAGGYAEGG-LP
MSMEG_5630|M.smegmatis_MC2_155      -----------------MTVSPAEHRYLQVARTLRKEIVDGVYPVGSHLP
                                                                 :   *:  *       *  **

Mflv_0447|M.gilvum_PYR-GCK          TESELVARLGLSRQTVRRAFQDLVAEGAVYRVPGRGSYAGDR--GRRYLR
Mvan_0220|M.vanbaalenii_PYR-1       TESELVARHGLSRQTVRRAFQDLVAEGTVYRVPGRGSYASEQ--GRRYLR
TH_4188|M.thermoresistible__bu      TESELMAQYGVSRQTVRRAFQDLVAEGSVYRVPGRGTYAAD-----RYLR
Mb0816c|M.bovis_AF2122/97           SERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQGLGTFVADP--VEQELS
Rv0792c|M.tuberculosis_H37Rv        SERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQGLGTFVADP--VEQELS
MAV_0738|M.avium_104                TERELVDRTRVSRVTVRAAVGLLERQGWLVRRQGLGTFVANP--VKQELG
MMAR_2560|M.marinum_M               TEQELIARSGVSRSTVRAAVGILEDEGWLVRRQGLGTFVAEP--VKQDLE
MUL_3201|M.ulcerans_Agy99           TEQELIARSGVSRSTVRAAVGILEDEGWLVRRQGLGTFVAEP--VEQDLE
MAB_2239|M.abscessus_ATCC_1997      SEHALAAEFFVSRNTVREALTTLKDEGLIERGPRTGTHVALRK-YEHGLD
MSMEG_5630|M.smegmatis_MC2_155      TEHELCERFEVSRYTIREALRRLRDDNLVESRPRAGTTVVPRPTTNSYAQ
                                    :*  *  .  :** *:* *.  *  :. :      *: .           

Mflv_0447|M.gilvum_PYR-GCK          QLGSIEDLLSLSEDTTMEVLDGLRRRVDIDAASRLRLDG-DVVYTVVFRR
Mvan_0220|M.vanbaalenii_PYR-1       QLGSIEDLMSLSDDTTMEVVDGLRRRVDIEAASRLRLDG-DVVYSVQFRR
TH_4188|M.thermoresistible__bu      QFGSIEDLMALSDDTTMEVRSGLRRRVDVDAASRLRLDD-DVVHTVVFRR
Mb0816c|M.bovis_AF2122/97           CGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGL-VEVLCIRRRI
Rv0792c|M.tuberculosis_H37Rv        CGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGL-VEVLCIRRRI
MAV_0738|M.avium_104                PGVRTITEVLAASGITPNVDVLSHRVEDAPQRIAETLHL-TKVLCVHRRF
MMAR_2560|M.marinum_M               SGVRTITEVLLSRGVTPRVEVLSHAVVAAPQSVGAALGR-SEVLRIQRRY
MUL_3201|M.ulcerans_Agy99           SGVRTITEVLLSRGVTPRVEVLAHAVVAAPQSVGAALGR-SEVLRIQRRY
MAB_2239|M.abscessus_ATCC_1997      ALLGLKETFKGYGEVRNEVRVIQEVNAPPAVAHRLRLDPGARVIFIERLR
MSMEG_5630|M.smegmatis_MC2_155      DVMSINDLLAFATGAQFTIDSNAMVTIDDELAERTGLPVDEEWLAVRGYR
                                            .         :                 *        :    

Mflv_0447|M.gilvum_PYR-GCK          LHDGI--AFGHTMVHLPPAVAAPVLASPHLMTGAVSTHT------VIGLL
Mvan_0220|M.vanbaalenii_PYR-1       LHGGI--AFGHTTVALPPAVATSVLTSPHLVTGATSTHT------VIGLL
TH_4188|M.thermoresistible__bu      LHAGA--PFVSTVVHLPDRAAHHLHGCAELRTGAVSTHT------VIGLL
Mb0816c|M.bovis_AF2122/97           RTGDQ--PLALVTAYLPPGVG---PAVEPLLSGSADTET------TYAMW
Rv0792c|M.tuberculosis_H37Rv        RTGDQ--PLALVTAYLPPGVG---PAVEPLLSGSADTET------TYAMW
MAV_0738|M.avium_104                RDGEQ--PLALMIAYLPPGLG---EAVEPLLKSATDTQTGRAMESTYTMW
MMAR_2560|M.marinum_M               SESDQ--PLAIVTCYLPADLPH--DAVEPLLSATSATAT------TYTMW
MUL_3201|M.ulcerans_Agy99           SESDQ--PLAIVTCYLPTDLPH--DAVEPLLSATSVTAT------TYTMW
MAB_2239|M.abscessus_ATCC_1997      YLGDL--PLSLDKTYLTPDVG------EAVIEHQLETND------VFALI
MSMEG_5630|M.smegmatis_MC2_155      QAEGNKPPVCRTEYYINRSFA--------AVGRLLQRHTG----PIFPLI
                                           ..      :                                : 

Mflv_0447|M.gilvum_PYR-GCK          EPHLERPIDEAAQSITVVSADEAAAAAVHCAPGHPMLRVDRLYADDEGRP
Mvan_0220|M.vanbaalenii_PYR-1       EPHLEKPIAEAAQSITVAAADEAAAAAVACPPGHPMLRVDRLYADDEGHP
TH_4188|M.thermoresistible__bu      EPHLEEPIDQAAQSITVAPADDDTADAVGVEPGHPMLRIDRLYSDRTGRP
Mb0816c|M.bovis_AF2122/97           ERRLGVRIAQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGKP
Rv0792c|M.tuberculosis_H37Rv        ERRLGVRIAQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGKP
MAV_0738|M.avium_104                ERRLDTPIARASYEIHAAGASVEVAGALNLPLGSPVLVLERTSYGHDDTP
MMAR_2560|M.marinum_M               EQRLGVRISSATHEIQAAGASPEIAAALGLSEGAPVLVLRRTSYTDGDKP
MUL_3201|M.ulcerans_Agy99           EQRLGVRISSATHEVQAAGASPEIASALGLSEGAPVLVLRRTSYTDGDKP
MAB_2239|M.abscessus_ATCC_1997      ERVTGRRLGSANLALEAVAADSHSAATLQVPDSAPLLLLERLTHLDDGTP
MSMEG_5630|M.smegmatis_MC2_155      EDLFGVSVVEVHQQITAVLVDTDLAELLKVSPGTAALQMQRTYTTSDGEI
                                    *      :  .   : .. ..   *  :    . . * : *      .  

Mflv_0447|M.gilvum_PYR-GCK          VELAVSQFLPEQYTYRVTLRRSG--------------
Mvan_0220|M.vanbaalenii_PYR-1       VELAVSQFLPEQYTYRVTLRRSS--------------
TH_4188|M.thermoresistible__bu      VELSVSHFLPEQYTYRVTLRRE---------------
Mb0816c|M.bovis_AF2122/97           LEVVVFHHRPERYQFSVTLPRTLPGSGAGIIEKRDFA
Rv0792c|M.tuberculosis_H37Rv        LEVVVFHHRPERYQFSVTLPRTLPGSGAGIIEKRDFA
MAV_0738|M.avium_104                LEVVEFHYRPERYRFSVTLPRTVPGPGAGIVERSG--
MMAR_2560|M.marinum_M               LEVVLFHHRPERYEFCVTLPRTMPGQRAGMTER----
MUL_3201|M.ulcerans_Agy99           LEVVLFHHRPERYEFCVTLPRTMPGQRAGMTER----
MAB_2239|M.abscessus_ATCC_1997      VDLEYIRMRGDRITLRSNLLRDI--------------
MSMEG_5630|M.smegmatis_MC2_155      AQVTVNTHPSGRYRHSMTMRRVKG-------------
                                     ::        :     .: *