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LLATFWGWRAQQLPDGTVIWTLPGDQTYVTTPGSALLFPALCTPTGDPPRPDPARADRRGQRTAMMPRRA STRAQNRAHYIAAERHRNHQARRIAHVVTQTATTAPETNGPPPDPDDDPPPF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0397 | - | - | 100% (122) | CONSERVED 13E12 REPEAT FAMILY PROTEIN |
| M. tuberculosis H37Rv | Rv0393 | - | 3e-60 | 87.70% (122) | 13E12 repeat family protein |
| M. tuberculosis H37Rv | Rv0336 | - | 3e-39 | 63.71% (124) | 13E12 repeat family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0403 | - | 1e-72 | 100.00% (122) | 13E12 repeat family protein |
| M. gilvum PYR-GCK | Mflv_4099 | - | 4e-25 | 50.86% (116) | hypothetical protein Mflv_4099 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4752 | - | 3e-08 | 42.67% (75) | hypothetical protein MAB_4752 |
| M. marinum M | MMAR_5187 | - | 1e-29 | 54.84% (124) | 13e12 repeat-containing protein |
| M. avium 104 | MAV_3457 | - | 9e-39 | 62.30% (122) | 13e12 repeat-containing protein |
| M. smegmatis MC2 155 | MSMEG_3957 | - | 2e-18 | 43.97% (116) | 13e12 repeat-containing protein |
| M. thermoresistible (build 8) | TH_3753 | - | 6e-08 | 32.67% (101) | PUTATIVE putative aldehyde dehydrogenase |
| M. ulcerans Agy99 | MUL_1813 | - | 9e-19 | 77.55% (49) | 13e12 repeat-containing protein |
| M. vanbaalenii PYR-1 | Mvan_0728 | - | 8e-26 | 45.99% (137) | hypothetical protein Mvan_0728 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0397|M.tuberculosis_H37Rv --------------------------------------------------
Mb0403|M.bovis_AF2122/97 --------------------------------------------------
MAV_3457|M.avium_104 ---------MVEHMFEYVVASR----STPEAVALLDRAREAARAEARAAA
MUL_1813|M.ulcerans_Agy99 ----------------------------------MERAREASRREAAAAA
MMAR_5187|M.marinum_M MFESMGVAAGVDHPCDALAERRQLRTPTAESARWVQRIGAAARAENRAAA
MAB_4752|M.abscessus_ATCC_1997 ------------------------MFDELGDVELIDLIASAQRAEAQACA
MSMEG_3957|M.smegmatis_MC2_155 ------------------------MCETLDDAALIAGIAGESRAESAAAA
Mflv_4099|M.gilvum_PYR-GCK --------------MFDSLVPEPGALAGLSDAELVDAAGAAARAENAVCA
Mvan_0728|M.vanbaalenii_PYR-1 --------------MFDVLVPDPADLAALSDAELLDAATATTRAENAVCA
TH_3753|M.thermoresistible__bu ----------VQLPDGTVVWRAPSGRTYTTTPAGAEFFAQLGRPTGEVEV
Rv0397|M.tuberculosis_H37Rv --------------------------------------------------
Mb0403|M.bovis_AF2122/97 --------------------------------------------------
MAV_3457|M.avium_104 ARLVAVAELLVLR--CRETGERADWAADAWEAVAAQVGAALGCSVAMGHS
MUL_1813|M.ulcerans_Agy99 ERLDVVGALFVLR--CRESGDRAEWATDTWEAVGAQVAAALRTSVAMGSS
MMAR_5187|M.marinum_M AQLIEIGQLFAYR--LSRCSETEDWAVDTMEAVAAEVAAGLRISQGLAAS
MAB_4752|M.abscessus_ATCC_1997 RKLDAIGVLVDRHADLGKPDERDHHALDRWDRVASEVAAAQGITHALASS
MSMEG_3957|M.smegmatis_MC2_155 RRFAFIAEFVDRR-TADSEDTVVWWACDDWDAASAEVAAALNIGQRSASR
Mflv_4099|M.gilvum_PYR-GCK RKLAVMAELFTRR-VDLAPEDRLNWWVDPDAAVAAEIAAAVTITQGLATH
Mvan_0728|M.vanbaalenii_PYR-1 RKLAVMAELFIRR-TTLAPQDRLDWWVDPEAAVTAELAAAHHITQGLATH
TH_3753|M.thermoresistible__bu SQTKPPDGADRGAKMPLRPXXXEGPWPRMSPKERSAALHRVADRLEQLHA
Rv0397|M.tuberculosis_H37Rv --------------------------------------------------
Mb0403|M.bovis_AF2122/97 --------------------------------------------------
MAV_3457|M.avium_104 YLRYAMAMRERLPQVGAVFAAGGIDYRAFQTLVFRTDLITDAQVLARVDA
MUL_1813|M.ulcerans_Agy99 YLRYAMAMRNRLPKVGQAFRAEDIDYRAFQTIVFRTDLITDAEVLAKVDA
MMAR_5187|M.marinum_M RLRYARALRERLPKTGAVFAAGQIDLRAFQTIVFRTDLIVDPQVMAAVDA
MAB_4752|M.abscessus_ATCC_1997 QMRYAQVLRHRLRAVAERFAAGDLDFRTVALIINRTELVDDEAVVARVDA
MSMEG_3957|M.smegmatis_MC2_155 LMRIAVALRDRLPLVAAQFAEGAVSTRVVETLTWRTRLIDDTQTMAAVDA
Mflv_4099|M.gilvum_PYR-GCK QTYRAVVLRDRLPKVGALFLAGLLSELLVRAIITRTDLITDPELIAAVDA
Mvan_0728|M.vanbaalenii_PYR-1 QAYRAVVLRDRLPKIGALFLQGLLSELLVRAIITRTGLITDPDLIAAVDA
TH_3753|M.thermoresistible__bu PLSAALVEEVGTPITLATTLQAQLPVQVLREYADAAADIGVTHLGPHFDP
Rv0397|M.tuberculosis_H37Rv --------------------------------------------------
Mb0403|M.bovis_AF2122/97 --------------------------------------------------
MAV_3457|M.avium_104 TLAVLVSRRPSLTRGGLAAAVDRVVAAVDADAVRRARDAVTGRYLDVR--
MUL_1813|M.ulcerans_Agy99 QLAALLARCPAVTRGRLSVAVDQVVADVDRDVVRRVAEAADGRFVDVDVI
MMAR_5187|M.marinum_M LVALNVGRWPSMTKARLSGQIDAIVARADADAVRRRKERHADREIWIG--
MAB_4752|M.abscessus_ATCC_1997 AIVRALPRWARWSHKRITAALDALVLHFDQDAVRRNRSATDKRHLEIRPL
MSMEG_3957|M.smegmatis_MC2_155 QLASRIAEFGAMTIAELEGAVDKVVDSVDPAAVRRTRTAVRSRGVWFGHP
Mflv_4099|M.gilvum_PYR-GCK DLAADILRWGPQSAKKTEAAIDHIVERHDPDAVRQSRQHDVGRTIEIGNP
Mvan_0728|M.vanbaalenii_PYR-1 DLATDILDWGPLSVKATEAEIDAIIDRHDPDAVRKSRAPETGRTVQFGNP
TH_3753|M.thermoresistible__bu VPSSSYVARRPMGVAAVIAAYN----FPILLAIRSAGAALAAGCTVVLLP
Rv0397|M.tuberculosis_H37Rv --------------------------------------------------
Mb0403|M.bovis_AF2122/97 --------------------------------------------------
MAV_3457|M.avium_104 ANESGMAWVEGNVLGPDGHALDRRLDELASGVCAGDPRSRAQRRADALGA
MUL_1813|M.ulcerans_Agy99 ADGSGLAALAGSVLATAGRAFDRRLDELANTVCAADPRTREQRRADAVGA
MMAR_5187|M.marinum_M QDADGISRIDGSMFTIDAHALDRRLSALAATVCAQDPRSREQRRADALGV
MAB_4752|M.abscessus_ATCC_1997 GNGEPVAEVWGTLQAVHAVALDKRLDLLAGTVCPADPRSKTQRRADAVGA
MSMEG_3957|M.smegmatis_MC2_155 DDETGITSVHARLTNVDAVALKNRVGAMSSGQCPDDPRTKGQRLSDAMGV
Mflv_4099|M.gilvum_PYR-GCK GDAPGYTTVWARMFAGDAAAGHRTLTTMAYSVCDNDPRTLDERRNDALTA
Mvan_0728|M.vanbaalenii_PYR-1 GDAPGYTSMWARMYASDAAAADRTLTALAYSVCDNDPRTLDERRNDAHTA
TH_3753|M.thermoresistible__bu SPRTPLTTLLLHDIFSDLPPGTVNTVVGGPEIGRHLTTHPGVEKVAFTGS
Rv0397|M.tuberculosis_H37Rv --------------------------------------------------
Mb0403|M.bovis_AF2122/97 --------------------------------------------------
MAV_3457|M.avium_104 LAAGAGRLACGCGSPDCPSAAAPAPRSTVVIHVVAEQATVAG--------
MUL_1813|M.ulcerans_Agy99 LVAGSDRLACGCTSADCTAAARSAP-SKVVIHVVADQSTVDG--------
MMAR_5187|M.marinum_M LAAGGDRLGCRCGLPDCAAGARPAA-QPVVIHVIAERATLDG--------
MAB_4752|M.abscessus_ATCC_1997 LTQGLNRMRCACGHPDCSG--RDTADVPVVVNVVINQSTLAG--------
MSMEG_3957|M.smegmatis_MC2_155 LGHYGDRLTCRCGDPECPAAGIDPRAANTMVHVFAEPAAVHGPVDRYLDG
Mflv_4099|M.gilvum_PYR-GCK LFHGITTLACRCGHTDCDAATNPRPPRELTVYALTDQTAANAASEE----
Mvan_0728|M.vanbaalenii_PYR-1 LLTGITTLACQCGNPDCHASTNPRPPRDITVYALTDHTTT----------
TH_3753|M.thermoresistible__bu MAVGAQIMRQAADTAKSLSLELGDKSPAVVLPDADLAEQLPG--------
Rv0397|M.tuberculosis_H37Rv --------------------------------------------------
Mb0403|M.bovis_AF2122/97 --------------------------------------------------
MAV_3457|M.avium_104 ------------------------------------------RGATPAVV
MUL_1813|M.ulcerans_Agy99 ------------------------------------------TGHTPAVL
MMAR_5187|M.marinum_M ------------------------------------------DGGAPAWE
MAB_4752|M.abscessus_ATCC_1997 ------------------------------------------SDDCPAHV
MSMEG_3957|M.smegmatis_MC2_155 DHESNPIPYFEPTPTPEPEPTPEPVRKPPEPEPKPWTPQSAHPGRGGAVV
Mflv_4099|M.gilvum_PYR-GCK ----------PRGDATDADAGAVDAQPATPPVK-PRRSKPTLLPGRSGYL
Mvan_0728|M.vanbaalenii_PYR-1 ------------TDTGDADT-TTDTKPPTPPAPQPRRSKPILIPGRPAYL
TH_3753|M.thermoresistible__bu --------------------------------------------------
Rv0397|M.tuberculosis_H37Rv --------------------------------------------------
Mb0403|M.bovis_AF2122/97 --------------------------------------------------
MAV_3457|M.avium_104 AGLDGLIPAQVIAELAASARLVPVAVP-EGGPEPGYTPSARLADFIRCRD
MUL_1813|M.ulcerans_Agy99 LGAEGLIPASLIAELAKVATLRPLMRP-SGRPESGYAPSAGLAEFVRCRD
MMAR_5187|M.marinum_M VGADGLVTPELVAELAKSAKLVPLRHPGDVPPEPGYVPSKALADFVRCRD
MAB_4752|M.abscessus_ATCC_1997 PGFG-----VLAAESARAAVAGTPTRNLTDSRSTGYRPSAKLAAFVRSRD
MSMEG_3957|M.smegmatis_MC2_155 LGGGVVPAPLVAQLIADGAKVKELTVP--DDICASYRPSVAMDCFVRMRD
Mflv_4099|M.gilvum_PYR-GCK FGSGFMPAPLFDALLDGAKIREILHPG-QAGPEPRYTPSTALADFIRCRD
Mvan_0728|M.vanbaalenii_PYR-1 FGAGFMPAPLFDALLAEATIREIIHPGNRSAPEPRYTPSQALAEFIRCRD
TH_3753|M.thermoresistible__bu ---------ILLGYLANSGQSCGATTRLIVPREKVEEFIAGSQAFIEGVL
Rv0397|M.tuberculosis_H37Rv ------------------------------------------MLATFWG-
Mb0403|M.bovis_AF2122/97 ------------------------------------------MLATFWG-
MAV_3457|M.avium_104 LTCRAPGCDRPAVDCDVDHTIPYAQGGPTHPSNLKCLCRGHHLLKTFWG-
MUL_1813|M.ulcerans_Agy99 LTCRARGCDQPAVCCDLDHTVAYGDGGHTHASNLKCLCRKHHLLKTFWG-
MMAR_5187|M.marinum_M LTCRWPGCDHPALNCDLDHTIPYAQGGPTHASNLKCYCRTHHLVKTFWG-
MAB_4752|M.abscessus_ATCC_1997 QLCRFPGCEAVADRADIDHTVPWATGGPTTGANLKALCRKHHLLKTFGQ-
MSMEG_3957|M.smegmatis_MC2_155 MTCRFPGCSRPADFCDVDHTTPWPTG-VTHPSNTKCLCRIHHLLKTFWLG
Mflv_4099|M.gilvum_PYR-GCK LTCRFPGCDTPATEADIDHTVAHPVG-PTHASNLKCLCRFHHLLKTFWTG
Mvan_0728|M.vanbaalenii_PYR-1 LTCRFPGCDKPATEADIDHTVPYPIG-PTHPSNLKCLCRFHHLLKTFWLG
TH_3753|M.thermoresistible__bu VGDPWDPATVIGPLIRPEHRDFVRSHVEKAIRNGADVIARGRSVDALPG-
: ::
Rv0397|M.tuberculosis_H37Rv ---WRAQQLPDGTVIWTLPGDQTYVTTPGSALLFPALCTPTGDPPRP---
Mb0403|M.bovis_AF2122/97 ---WRAQQLPDGTVIWTLPGDQTYVTTPGSALLFPALCTPTGDPPRP---
MAV_3457|M.avium_104 ---WRDRQLPDGTVIWTLPDGDTYVTTPGSALLFPTLCTPTGAVSP----
MUL_1813|M.ulcerans_Agy99 ---WRDLQLPDGTVIWLLPDGHTYVTTPGSALLFPNLCVPTGELPPIVGT
MMAR_5187|M.marinum_M ---WHDQQLPDGTLILTSPAGHTYVTTPGSALLFPSLCHSTGGLPA----
MAB_4752|M.abscessus_ATCC_1997 ---WTELQEPDGTVIWKSPTGHRYATTPVSWFLFPALTR-----------
MSMEG_3957|M.smegmatis_MC2_155 ---WSDRQLPDGTVIWTSPTGHVYTTVPASRALFPQWDTTTAALPP----
Mflv_4099|M.gilvum_PYR-GCK PGGWHDRQDPDGTITWTAPTGHTYITHPGSRLLFPTLCKPTATLWAG---
Mvan_0728|M.vanbaalenii_PYR-1 ATGWHDRQHPDGTITWTAPTGHTYTTHPGSRLLFPTLCQPTATLWTG---
TH_3753|M.thermoresistible__bu ---WYHEPVLLAGVDSRAEIAQQELFGPVAVLLVYDDVEEAVKLAN----
* . : . * : *.
Rv0397|M.tuberculosis_H37Rv ---------------------DPARADRRGQRTAMMPRRASTRAQNRAHY
Mb0403|M.bovis_AF2122/97 ---------------------DPARADRRGQRTAMMPRRASTRAQNRAHY
MAV_3457|M.avium_104 --------------------AKPDTEHRCGERTAMMPLRRHTRAHNRAHR
MUL_1813|M.ulcerans_Agy99 AGKPPRWPSGEDADPCPNPRTKPGESHRHRAPMQSQGTGSRRRRPRRPVR
MMAR_5187|M.marinum_M ------------------AEADPPSDH-CDQRSAMMPRRQRTRAQDRARR
MAB_4752|M.abscessus_ATCC_1997 ---------------------------------------HHTRQQARDRR
MSMEG_3957|M.smegmatis_MC2_155 ----------------PPTPPPPMTPSEIAARAAMMPRRRRTRAAEEARR
Mflv_4099|M.gilvum_PYR-GCK ---------------------DPPQVPIRERRGAMMPRRAKTRAQNRAAY
Mvan_0728|M.vanbaalenii_PYR-1 ---------------------EPPQVPQSQQRGAMMPRRRNTRAHNHAAY
TH_3753|M.thermoresistible__bu ---------------------DTPYGLHGKVFTADVRAGLEVAARIRAGS
.
Rv0397|M.tuberculosis_H37Rv IAAERHRNHQARRIAHVVTQTATTAPETNGP--------PPDPDDDPPPF
Mb0403|M.bovis_AF2122/97 IAAERHRNHQARRIAHVVTQTATTAPETNGP--------PPDPDDDPPPF
MAV_3457|M.avium_104 ITTERNHNRR-------TRLTTHPATPGPAP--------PPDPDDEPPPF
MUL_1813|M.ulcerans_Agy99 HPGAGNRSRRAAALLAATSLGTCQIPRRIAP--------RPGPSRSSRGC
MMAR_5187|M.marinum_M VATERRQNHH------ARSTQPGGQPRSAAP--------PTPPQSEPQSH
MAB_4752|M.abscessus_ATCC_1997 RRTERNLNRE------------QRLQREAAL--------AALAAKDPPPF
MSMEG_3957|M.smegmatis_MC2_155 LAAERARNEA-------------YLAQRDRP--------PPDAHGPGMQ-
Mflv_4099|M.gilvum_PYR-GCK ITAERTHNVEHR--TDS--------PR----------------GNDPP-F
Mvan_0728|M.vanbaalenii_PYR-1 ITAERRRNAQTR--YATTGNTPPYLPRDHIPYQSSTGWREPDYGNDPPPF
TH_3753|M.thermoresistible__bu VQVNGGGFRADAP---FGGMKASGIGREYGMWG-----IQEFSEVQHIQW
Rv0397|M.tuberculosis_H37Rv ----------------------
Mb0403|M.bovis_AF2122/97 ----------------------
MAV_3457|M.avium_104 ----------------------
MUL_1813|M.ulcerans_Agy99 TDSGTRMGESSMSARPRACVAG
MMAR_5187|M.marinum_M PPPF------------------
MAB_4752|M.abscessus_ATCC_1997 ----------------------
MSMEG_3957|M.smegmatis_MC2_155 ----------------------
Mflv_4099|M.gilvum_PYR-GCK ----------------------
Mvan_0728|M.vanbaalenii_PYR-1 ----------------------
TH_3753|M.thermoresistible__bu AW--------------------