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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3753 | - | - | 100% (485) | putative aldehyde dehydrogenase |
| M. thermoresistible (build 8) | TH_3902 | - | 7e-90 | 39.35% (493) | PUTATIVE putative 5-carboxymethyl-2-hydroxymuconate |
| M. thermoresistible (build 8) | TH_3080 | - | 5e-86 | 40.04% (472) | PUTATIVE aldehyde dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0791 | aldA | 1e-75 | 38.15% (464) | aldehyde dehydrogenase NAD dependant AldA |
| M. gilvum PYR-GCK | Mflv_0428 | - | 7e-87 | 40.17% (463) | betaine-aldehyde dehydrogenase |
| M. tuberculosis H37Rv | Rv0223c | - | 2e-82 | 36.78% (454) | aldehyde dehydrogenase |
| M. leprae Br4923 | MLBr_02573 | gabD1 | 8e-45 | 29.44% (411) | succinic semialdehyde dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4484 | - | 9e-91 | 40.86% (465) | aldehyde dehydrogenase |
| M. marinum M | MMAR_0472 | - | 8e-85 | 38.16% (456) | aldehyde dehydrogenase |
| M. avium 104 | MAV_2647 | - | 3e-83 | 40.58% (483) | betaine-aldehyde dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_0309 | - | 4e-89 | 39.52% (463) | aldehyde dehydrogenase family protein |
| M. ulcerans Agy99 | MUL_1122 | - | 1e-83 | 37.72% (456) | aldehyde dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_0240 | - | 3e-87 | 40.27% (452) | betaine-aldehyde dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0428|M.gilvum_PYR-GCK ---MTQS----TAFRTEWDKLFIGGKWVEPASSEVIEVRSPATGDVVGKV
Mvan_0240|M.vanbaalenii_PYR-1 ---MTQS----TTFRTEWDKLFIGGKWVEPATSDVIEVHSPATGELVGKV
MSMEG_0309|M.smegmatis_MC2_155 MTAMTQTAPAATAATTNWDKLFIGGQWVEPSSSEIIEVFSPATGEKVGQA
MMAR_0472|M.marinum_M -----------MGEKTEYDKLFIGGKWTEPSTSEVIEVHCPATGEYVGKV
MUL_1122|M.ulcerans_Agy99 -----------MGEKTEYDKLFIGGRWTEPSTSEVIEVHCPATGEYVGKV
Rv0223c|M.tuberculosis_H37Rv ----------MSDSATEYDKLFIGGKWTKPSTSDVIEVRCPATGEYVGKV
MAB_4484|M.abscessus_ATCC_1997 --------------MTNYDKLFIGGVWTEPATDQVIEVISPATGQKVGQC
MAV_2647|M.avium_104 -----MTLLPESVPMVELAASYAAGKWVSGAHAGTLDVTSPATGELLGTV
TH_3753|M.thermoresistible__bu --------VQLPDGTVVWRAPSGRTYTTTPAGAEFFAQLGRPTGEVEVSQ
Mb0791|M.bovis_AF2122/97 ----------MALWGDGISALLIDGKLSD-GRAGTFPTVNPATEEVLGVA
MLBr_02573|M.leprae_Br4923 ---------------------------------MSIATINPATGETVKTF
: .* :
Mflv_0428|M.gilvum_PYR-GCK PLASAADVDAACAAAREAFDNGPWPQMSPTERAEVLGRAVKLMEERADEL
Mvan_0240|M.vanbaalenii_PYR-1 PLASAADVDAACAAAREAFDNGPWPHMSPAERGEILGRAVKIMEERADEL
MSMEG_0309|M.smegmatis_MC2_155 PLATKADVDAACAAARKAFDEGPWPRMTPQEREAVLAKATALIEESADEF
MMAR_0472|M.marinum_M PLAAAADVDAAVAAARAAFDNGPWPSTPPKERATVIANALKLLEERKDHF
MUL_1122|M.ulcerans_Agy99 PLAAAADVDAAVAAARAAFDNGPWPSTPPKERATVIANALKLLEERKDHF
Rv0223c|M.tuberculosis_H37Rv PMAAAADVDAAVAAARAAFDNGPWPSTPPHERAAVIAAAVKMLAERKDLF
MAB_4484|M.abscessus_ATCC_1997 PLASPADVDAAVSAARRAFDNGPWPRLTPHERQAVLQKAVSLLESRKDEI
MAV_2647|M.avium_104 GIAGPDDVGAAVAAARGALQS--WGRVAPADRGAALGRLADALSARKGEL
TH_3753|M.thermoresistible__bu TKPPDGADRGAKMPLRPXXXEGPWPRMSPKERSAALHRVADRLEQLHAPL
Mb0791|M.bovis_AF2122/97 ADADAEDMGRAIEAARRAFDSTDWSRN-TELRVRCVRQLRDAMQQHVEEL
MLBr_02573|M.leprae_Br4923 TPTTQDEVEDAIARAYARFDN--YRHTTFTQRAKWANATADLLEAEANQS
. * . : * :
Mflv_0428|M.gilvum_PYR-GCK KFLLAAETGQPPTIVDMMQYGAAMSSFQFYAG-AADKFTWQDIR-----D
Mvan_0240|M.vanbaalenii_PYR-1 KFLLAAETGQPPTIVDMMQYGAAMSSFQFYAG-AADKFTWQDIR-----D
MSMEG_0309|M.smegmatis_MC2_155 KTLLKLETGQPQTIVDMMQYGAAMSTLQFYAS-AADKFAWKDIR-----D
MMAR_0472|M.marinum_M AKLLADETGQPPMTVETMHWMGSIGALNFFAGPAVDQVRWKEIR-----N
MUL_1122|M.ulcerans_Agy99 AKLFADETGQPPMTVETMHWMGSIGALNFFAGPAVDQVRWKEIR-----N
Rv0223c|M.tuberculosis_H37Rv TKLLAAETGQPPTIIETMHWMGSMGAMNYFAG-AADKVTWTETR-----T
MAB_4484|M.abscessus_ATCC_1997 CKAIADETGAPPMVIETLQWMGGFGAIQYYAN-AADAVKWKELR-----N
MAV_2647|M.avium_104 ADLTTAEIGSPRSWSTFGQVITAVGVLRAYAS-ITPHYPFSTTR-----P
TH_3753|M.thermoresistible__bu SAALVEEVGTPITLATTLQAQLPVQVLREYAD-AAADIGVTHLGPHF--D
Mb0791|M.bovis_AF2122/97 RELTISEVGAPRMLTASAQLEGPVGDLSFAAD-TAESYPWKQDLGEASPL
MLBr_02573|M.leprae_Br4923 AALMTLEMG-KTLQSAKDEAMKCAKGFRYYAEKAETLLADEPAEA----A
* * . : *
Mflv_0428|M.gilvum_PYR-GCK GVYGQTLVVRE-PVGVVGAVTAWNVPFFLAANKLGPALLAGCTVVLKPAA
Mvan_0240|M.vanbaalenii_PYR-1 GVYGQTLVVRE-PVGVVGAVTAWNVPFFLAANKLGPALLAGCTVVLKPAA
MSMEG_0309|M.smegmatis_MC2_155 GIYGQTLVLKE-PVGVVGAVVAWNVPFFLAANKLGPALLAGCTIVLKPAA
MMAR_0472|M.marinum_M GSYGQTIVHRE-PIGVVGAIVAWNVPLFLAINKLGPALLAGCTVVLKPAA
MUL_1122|M.ulcerans_Agy99 GSYGQTIVHRE-PIGVVGAIVAWNVPLFLAINKLGPAPLAGCTVVLKPAA
Rv0223c|M.tuberculosis_H37Rv GSYGQSIVSRE-PVGVVGAIVAWNVPLFLAVNKIAPALLAGCTIVLKPAA
MAB_4484|M.abscessus_ATCC_1997 GAYGQTLVTRE-PAGVVAAIAAWNVPLFLALNKIGPAFLAGCAVVLKPAA
MAV_2647|M.avium_104 SVTGGTVEVRQLPVGVVGAIVPWNTPLFIAALKLGPALAAGCTVVLKPAP
TH_3753|M.thermoresistible__bu PVPSSSYVARR-PMGVAAVIAAYNFPILLAIRSAGAALAAGCTVVLLPSP
Mb0791|M.bovis_AF2122/97 GIATRRTLARE-AVGVVGAITPWNFPHQINLAKLGPALAAGNTVVLKPAP
MLBr_02573|M.leprae_Br4923 AVGASKALARYQPLGVVLAVMPWNFPLWQTVRFAAPALMAGNVGLLKHAS
: . **. .: .:* * ..* ** . :* :.
Mflv_0428|M.gilvum_PYR-GCK ETPLSVFAMAEMFVEA-GLPEGVLSIVPGG-PETGQALTANPNLDKYTFT
Mvan_0240|M.vanbaalenii_PYR-1 ETPLSVFAMAEMFVEA-GLPEGVLSIVPGG-PETGQALTANPNLDKYTFT
MSMEG_0309|M.smegmatis_MC2_155 ETPLTTNLMAQKFLEA-GLPEGVLSVVPGG-PETGRALTDNPALDKFTFT
MMAR_0472|M.marinum_M ETPLTANALAEVFAEA-GLPEGVLSVVPGG-VETGQALTSNPGVDLFTFT
MUL_1122|M.ulcerans_Agy99 ETPLTANALAEVFAEA-GLPEGVLSVVPGG-VETGQALTSNPGVDLFTFT
Rv0223c|M.tuberculosis_H37Rv ETPLTANALAEVFAEV-GLPEGVLSVVPGG-IETGQALTSNPDIDMFTFT
MAB_4484|M.abscessus_ATCC_1997 ETPLSSFILAEVFAEA-GVPEGVLSVVPGG-AETGRALTNNPDVDVFSFT
MAV_2647|M.avium_104 DAPLEFGVLMEAIEEA-GLPDGVVNVVNGG-AETGELLTEHPGVDKVSFT
TH_3753|M.thermoresistible__bu RTPLTTLLLHDIFSD---LPPGTVNTVVGG-PEIGRHLTTHPGVEKVAFT
Mb0791|M.bovis_AF2122/97 DTPWCAAALGEIIVEHTDFPPGVVNIVTSSSHALGALLAKDPRVDMISFT
MLBr_02573|M.leprae_Br4923 NVPQCALYLADVIARG-GFPEDCFQTLLIS-ANGVEAILRDPRVAAATLT
.* : : : .* . .. : . : .* : ::*
Mflv_0428|M.gilvum_PYR-GCK GSSGVGKEIAKIAADKLKPCTLELGGKSAAIILEDADLDSTLPMLVFSGL
Mvan_0240|M.vanbaalenii_PYR-1 GSSGVGKEIAKIAADKLKPCTLELGGKSAAIILEDADLDSTLPMLVFSGL
MSMEG_0309|M.smegmatis_MC2_155 GSSAVGKEIGKIAAEKLKPCTLELGGKSAAIILEDADLDSTLPMLLFSGL
MMAR_0472|M.marinum_M GSSAVGKEIGRRAAEMLKPCTLELGGKSAAILLEDVDLSTAVPMMVFSGI
MUL_1122|M.ulcerans_Agy99 GSSAVGKEIGRRAAEMLKPCTLELGGKSAAILLEDVDLSTAVPMMVFSGI
Rv0223c|M.tuberculosis_H37Rv GSSAVGREVGRRAAEMLKPCTLELGGKSAAIILEDVDLAAAIPMMVFSGV
MAB_4484|M.abscessus_ATCC_1997 GSTAVGKEIAEIAAKNLKKVTLELGGKSAAIVLEDADLAAALPMLVFSGL
MAV_2647|M.avium_104 GSTAVGARIAASCGSRIRRCSTELGGKSAAIVLPDAPLETTVPGLVAGVM
TH_3753|M.thermoresistible__bu GSMAVGAQIMRQAADTAKSLSLELGDKSPAVVLPDADLAEQLPGILLGYL
Mb0791|M.bovis_AF2122/97 GSTATGRAVMADAAATIKKVFLELGGKSAFVVLDDADLAAASAVSAFSAC
MLBr_02573|M.leprae_Br4923 GSEPAGQAVGAIAGNEIKPTVLELGGSDPFIVMPSADLDAAVATAVTGRV
** .* : .. : ***.... ::: .. * . .
Mflv_0428|M.gilvum_PYR-GCK MNSGQACVGQTRILAPRSRYDEVIEKLGEAVRNMAPGLPDNPAAMIGPLI
Mvan_0240|M.vanbaalenii_PYR-1 MNSGQACVGQTRILAPRSRYDEVVEKLAAAAAGMAPGLPDNPAAMIGPLI
MSMEG_0309|M.smegmatis_MC2_155 MNSGQACVGQTRILAPRSRYDEVVEKVAAGVAAMQVGVPDDPAAMVGPLI
MMAR_0472|M.marinum_M MNTGQACVGQTRILAPRSRYEEIVEAVSAFVQALPVGPPSDPAAQIGSLI
MUL_1122|M.ulcerans_Agy99 MNTGQACVGQTRILAPRSRYEEIVEAVSAFVQTLPVGPPSDPAAQIGSLI
Rv0223c|M.tuberculosis_H37Rv MNAGQGCVNQTRILAPRSRYDEIVAAVTNFVTALPVGPPSDPAAQIGPLI
MAB_4484|M.abscessus_ATCC_1997 MNAGQGCVNQTRVLAPRSRYDEVVDGIVGMVSLMGVGLPDDPATQVGPLI
MAV_2647|M.avium_104 GNNGQLCAALTRIVLPRSRYDEFVAALTAAVAELIVGDPADRVTDIGPLI
TH_3753|M.thermoresistible__bu ANSGQSCGATTRLIVPREKVEEFIAGSQAFIEGVLVGDPWDPATVIGPLI
Mb0791|M.bovis_AF2122/97 MHAGQGCAITTRLVVPRARYEEAVAIAAATMSSIRPGDPNDPGTVCGPLI
MLBr_02573|M.leprae_Br4923 QNNGQSCIAAKRFIAHADIYDEFVEKFVARMETLRVGDPTDPDTDVGPLA
: ** * .*.: :* : : * * : : *.*
Mflv_0428|M.gilvum_PYR-GCK SEKQRDRVEGYIKKGIEEGARVITGGGRPEGLDSGWFVEPTVFADVDNSM
Mvan_0240|M.vanbaalenii_PYR-1 SEKQRDRVEGYIKKGIEEGARVVTGGGRPEGLDSGWYVQPTVFADVDNSM
MSMEG_0309|M.smegmatis_MC2_155 SEKQRERVEGYIKKGIEEGARLVTGGGRPEGLDSGWFVQPTVFADVDNSM
MMAR_0472|M.marinum_M SEKQRARVEGYIAKGIEEGARLVSGGGRPEGLDNGFFVQPTVFADVDNKM
MUL_1122|M.ulcerans_Agy99 SEKQRARVEGYIAKGIEEGARLVSGGGRPESLDNGFFVQPTVFADVDNKM
Rv0223c|M.tuberculosis_H37Rv SEKQRTRVEGYIAKGIEEGARLVCGGGRPEGLDNGFFIQPTVFADVDNKM
MAB_4484|M.abscessus_ATCC_1997 TEKQRTRVEGYIAKGIAEGARLAYGGKRPEGLDGGYFVQPTIFADVDNSM
MAV_2647|M.avium_104 NEAARDRVEGFLRRARQDGATVLVGGERPN--RPGWFLSPAVVAATN-DM
TH_3753|M.thermoresistible__bu RPEHRDFVRSHVEKAIRNGADVIARG-RSVDALPGWYHEPVLLAGVDSRA
Mb0791|M.bovis_AF2122/97 SARQRDRVQGYLDLAVAEGGRFACGGARPADREVGFYIEPTVIAGLTNDA
MLBr_02573|M.leprae_Br4923 TESGRAQVEQQVDAAAAAGAVIRCGGKRPD--RPGWFYPPTVITDITKDM
* *. : . *. . * *. *:: *.:.:
Mflv_0428|M.gilvum_PYR-GCK TIAQEEIFGPVLSVIPYEDE-----DDAVRIANDSVYGLAGSVYTTDNDR
Mvan_0240|M.vanbaalenii_PYR-1 TIAQEEIFGPVLAVIPYEDE-----DDAVRIANDSVYGLAGSVYTTDNDR
MSMEG_0309|M.smegmatis_MC2_155 TIAQEEIFGPVLVVIPFEDE-----DDAVRIANDSVYGLAGSVYTTDHAK
MMAR_0472|M.marinum_M TIAQEEIFGPVLVVIPYDTE-----EDAIKIANDSVYGLAGSVWTSNVPK
MUL_1122|M.ulcerans_Agy99 TIAQEEIFGPVLVVIPYDTK-----EDAIKIANDSVYGLAGSVWTSNVPK
Rv0223c|M.tuberculosis_H37Rv TIAQEEIFGPVLAIIPYDTE-----EDAIAIANDSVYGLAGSVWTTDVPK
MAB_4484|M.abscessus_ATCC_1997 TIAQEEIFGPVLSIIAYDSV-----DEAVKIANDSNYGLAGSVWTTDVQK
MAV_2647|M.avium_104 EIAREEVFGPVAVVIAYDDTGADDVAEAVAIANDSRYGLVGAVWSADAER
TH_3753|M.thermoresistible__bu EIAQQELFGPVAVLLVYDDV-----EEAVKLANDTPYGLHGKVFTADVRA
Mb0791|M.bovis_AF2122/97 RVAREEIFGPVLTVIAHDGD-----DDAVRIANDSPYGLSGTVYGADPQR
MLBr_02573|M.leprae_Br4923 ALYTDEVFGPVASVYCATNI-----DDAIEIANATPFGLGSNAWTQNESE
: :*:**** : :*: :** : :** . .: :
Mflv_0428|M.gilvum_PYR-GCK ALKIARRIRTGTYAVN-MYAFDPCAPFGGYKNSGIGRENGWEGIEAYCEQ
Mvan_0240|M.vanbaalenii_PYR-1 ALKIARRIRTGTYAVN-MYAFDPCAPFGGFKNSGIGRENGWEGIEAYCEP
MSMEG_0309|M.smegmatis_MC2_155 GVEIASKVRTGTYGIN-MYAFDPGAPFGGYKNSGIGRECGPEGIAGYCES
MMAR_0472|M.marinum_M GIEISEKIRTGTYAIN-WYAFDPCCPFGGYKNSGIGRENGPEGVEHFTQQ
MUL_1122|M.ulcerans_Agy99 GIEISEKIRTGTYAIN-WYAFDPCCPFGGYKNSGIGRENGPEGVEHFTQQ
Rv0223c|M.tuberculosis_H37Rv GIKISQQIRTGTYGIN-WYAFDPGSPFGGYKNSGIGRENGPEGVEHFTQQ
MAB_4484|M.abscessus_ATCC_1997 GLEVAAQIRTGTYGIN-WYAFDPSCPFGGYKQSGIGRENGPEGIEEYCEL
MAV_2647|M.avium_104 AAAVAAQLLVGSVAVNSTAVLDFASPFGGFKQSGIGREGGPEGIAGFVEH
TH_3753|M.thermoresistible__bu GLEVAARIRAGSVQVN-GGGFRADAPFGGMKASGIGREYGMWGIQEFSEV
Mb0791|M.bovis_AF2122/97 AARIASRLRVGTVNVNGGVWYCADAPFGGYKQSGIGREMGLLGFEEYLEA
MLBr_02573|M.leprae_Br4923 QRHFIDNIVAGQVFINGMTVSYPELPFGGIKRSGYGRELSTHGIREFCNI
. .: .* :* **** * ** *** . *. : :
Mflv_0428|M.gilvum_PYR-GCK KSILLPFGYTPPAS
Mvan_0240|M.vanbaalenii_PYR-1 KSILLPFGYTPAT-
MSMEG_0309|M.smegmatis_MC2_155 KSVLLPFGYTPE--
MMAR_0472|M.marinum_M KSVLMPMGYTLES-
MUL_1122|M.ulcerans_Agy99 KSVLMPMGYTLES-
Rv0223c|M.tuberculosis_H37Rv KSVLLPMGYTVA--
MAB_4484|M.abscessus_ATCC_1997 KSVLLPMGYTLESI
MAV_2647|M.avium_104 QAIIR---------
TH_3753|M.thermoresistible__bu QHIQWAW-------
Mb0791|M.bovis_AF2122/97 KLIATAAN------
MLBr_02573|M.leprae_Br4923 KTVWIA--------
: :