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MFDELGDVELIDLIASAQRAEAQACARKLDAIGVLVDRHADLGKPDERDHHALDRWDRVASEVAAAQGIT HALASSQMRYAQVLRHRLRAVAERFAAGDLDFRTVALIINRTELVDDEAVVARVDAAIVRALPRWARWSH KRITAALDALVLHFDQDAVRRNRSATDKRHLEIRPLGNGEPVAEVWGTLQAVHAVALDKRLDLLAGTVCP ADPRSKTQRRADAVGALTQGLNRMRCACGHPDCSGRDTADVPVVVNVVINQSTLAGSDDCPAHVPGFGVL AAESARAAVAGTPTRNLTDSRSTGYRPSAKLAAFVRSRDQLCRFPGCEAVADRADIDHTVPWATGGPTTG ANLKALCRKHHLLKTFGQWTELQEPDGTVIWKSPTGHRYATTPVSWFLFPALTRHHTRQQARDRRRRTER NLNREQRLQREAALAALAAKDPPPF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4752 | - | - | 100% (445) | hypothetical protein MAB_4752 |
| M. abscessus ATCC 19977 | MAB_1907 | - | 2e-19 | 26.59% (410) | hypothetical protein MAB_1907 |
| M. abscessus ATCC 19977 | MAB_2374c | - | 3e-08 | 35.63% (87) | hypothetical protein MAB_2374c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0528 | - | 1e-83 | 40.21% (470) | 13E12 repeat family protein |
| M. gilvum PYR-GCK | Mflv_3596 | - | 2e-78 | 39.75% (473) | hypothetical protein Mflv_3596 |
| M. tuberculosis H37Rv | Rv0515 | - | 2e-83 | 40.21% (470) | 13E12 repeat family protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_2226 | - | 1e-86 | 41.21% (478) | 13e12 repeat-containing protein |
| M. avium 104 | MAV_3457 | - | 3e-87 | 42.14% (477) | 13e12 repeat-containing protein |
| M. smegmatis MC2 155 | MSMEG_5026 | - | 3e-84 | 41.24% (485) | hypothetical protein MSMEG_5026 |
| M. thermoresistible (build 8) | TH_0334 | - | 1e-68 | 40.55% (365) | HNH endonuclease |
| M. ulcerans Agy99 | MUL_1813 | - | 1e-81 | 44.27% (393) | 13e12 repeat-containing protein |
| M. vanbaalenii PYR-1 | Mvan_3778 | - | 1e-78 | 40.21% (485) | hypothetical protein Mvan_3778 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3596|M.gilvum_PYR-GCK ----------------------------MDAMTSAARCESRAAAERLAAV
Mvan_3778|M.vanbaalenii_PYR-1 --------MFAY----------AEPAELIDAMSSAARAESAAIARRLEAV
MSMEG_5026|M.smegmatis_MC2_155 MGAGILERMFDG----------TSDAGLIDAIAEAKRQENAATARRLFAI
TH_0334|M.thermoresistible__bu --------MFES----------LDDGAVVDSIAAASREQSAACGREMLAI
Mb0528|M.bovis_AF2122/97 MPSPEAIAHFDERFECHAPRTTRVSAAFIDRICSATRAENRAAAAQLVAL
Rv0515|M.tuberculosis_H37Rv MPSPEAIAHFDERFECHAPRTTRVSAAFIDRICSATRAENRAAAAQLVAL
MMAR_2226|M.marinum_M --------MFEY---WYASRPTAESNALLERAREASRREAAAAAERLDVV
MUL_1813|M.ulcerans_Agy99 ----------------------------MERAREASRREAAAAAERLDVV
MAV_3457|M.avium_104 ----MVEHMFEY---VVASRSTPEAVALLDRAREAARAEARAAAARLVAV
MAB_4752|M.abscessus_ATCC_1997 --------MFDELG----------DVELIDLIASAQRAEAQACARKLDAI
:: * * : * . .: .:
Mflv_3596|M.gilvum_PYR-GCK ASLYRVRK-SMY--VEAGLWRTDVFEAVAAEVSAAQNISRWRAGSQVRMA
Mvan_3778|M.vanbaalenii_PYR-1 AALFRSRK-CDY--AEAGFLHTDVYEAVAAEVSAAQNISRSRAGYQVEMA
MSMEG_5026|M.smegmatis_MC2_155 GELDTRRA-IDL--AECNFWRTDPFEEVCAEVSAALRISRSRANWQVHLA
TH_0334|M.thermoresistible__bu GELYARRAPEDD--TERANWAIDGHANVVAEISAALNISRGRAAGRLQLA
Mb0528|M.bovis_AF2122/97 GELFAYRWSRCG---GREEWVMDTMAAVAAEVAAALRISQGLAASRLRYA
Rv0515|M.tuberculosis_H37Rv GELFAYRWSRCG---GREEWVMDTMAAVAAEVAAALRISQGLAASRLRYA
MMAR_2226|M.marinum_M GALFVLRCRESG---DRAEWATDTWEAVAAQVAAALRTSVAMGSSYLRYA
MUL_1813|M.ulcerans_Agy99 GALFVLRCRESG---DRAEWATDTWEAVGAQVAAALRTSVAMGSSYLRYA
MAV_3457|M.avium_104 AELLVLRCRETG---ERADWAADAWEAVAAQVGAALGCSVAMGHSYLRYA
MAB_4752|M.abscessus_ATCC_1997 G-VLVDRHADLGKPDERDHHALDRWDRVASEVAAAQGITHALASSQMRYA
. : * * * :::.** : . :. *
Mflv_3596|M.gilvum_PYR-GCK VSLYERLPQVAEVFYRGDIDQRMVQLTLSRT-ETVDDAIIAELDAALARR
Mvan_3778|M.vanbaalenii_PYR-1 VSLYTRLPKVAEAFARGDIDLRMVQIVLART-KNVEDDVIGGLDKAIAPK
MSMEG_5026|M.smegmatis_MC2_155 RVLRDRIPKVAAVFAQGDIDFRIVTKIATRT-ELVDPAAMPALDDVLARR
TH_0334|M.thermoresistible__bu IDLRERLPRVAAVFAAGDIDFRMVSALVNRSRNVVDPDLLARLDAALAAW
Mb0528|M.bovis_AF2122/97 RAMRERLPKTAEVFSAGDIGYLMFATIVYRTDLIVDPDVLAAVDAQLAAN
Rv0515|M.tuberculosis_H37Rv RAMRERLPKTAEVFSAGDIGYLMFATIVYRTDLIVDPDVLAAVDAQLAAN
MMAR_2226|M.marinum_M MAMRNRLPKVGQAFRAGDIDYRAFQTIVFRTDLITDAEVLAKVDAQLAAL
MUL_1813|M.ulcerans_Agy99 MAMRNRLPKVGQAFRAEDIDYRAFQTIVFRTDLITDAEVLAKVDAQLAAL
MAV_3457|M.avium_104 MAMRERLPQVGAVFAAGGIDYRAFQTLVFRTDLITDAQVLARVDATLAVL
MAB_4752|M.abscessus_ATCC_1997 QVLRHRLRAVAERFAAGDLDFRTVALIINRTELVDDEAVVARVDAAIVRA
: *: .. * .:. . *: : : :* :.
Mflv_3596|M.gilvum_PYR-GCK IVKWMRFSKDKLRDRLDQWVAKFDPAGVRVPPAAKDNRYFDVTP---DVP
Mvan_3778|M.vanbaalenii_PYR-1 LSRWMRLSKNDLRDRVDLWVADFDPAAVRVPPEAKDNRYFDVTP---DVP
MSMEG_5026|M.smegmatis_MC2_155 CPNWMRLSEPKLEERIDQCILRLDPDGQRVTKRSEDSRYFTVQPA--DTP
TH_0334|M.thermoresistible__bu SPKWMKLSGPTLNERIDMWVERFDPTGVREPRSPGEDRYVVVTP---AGQ
Mb0528|M.bovis_AF2122/97 VARWPSMTKARLAGQVDKIVARADADAVRRRKEYQAQRQFWVG---ESQD
Rv0515|M.tuberculosis_H37Rv VARWPSMTKARLAGQVDKIVARADADAVRRRKEYQAQRQFWVG---ESQD
MMAR_2226|M.marinum_M LARCPAVTRGRLSVAVDQVVADVDRDAVRRVAEAADGRFVDVDV-IADGS
MUL_1813|M.ulcerans_Agy99 LARCPAVTRGRLSVAVDQVVADVDRDVVRRVAEAADGRFVDVDV-IADGS
MAV_3457|M.avium_104 VSRRPSLTRGGLAAAVDRVVAAVDADAVRRARDAVTGRYLDVR---ANES
MAB_4752|M.abscessus_ATCC_1997 LPRWARWSHKRITAALDALVLHFDQDAVRRNRSATDKRHLEIRP-LGNGE
. : : :* : * * * . :
Mflv_3596|M.gilvum_PYR-GCK GMAFAGGVLTARDAAALDQRLEAMADTVCANDPRTWNQRRADAAGALGRG
Mvan_3778|M.vanbaalenii_PYR-1 GMAFAGGLLNARDAAALDQRLEAIAATVCSNDPRSHNNLRADAAGALGRG
MSMEG_5026|M.smegmatis_MC2_155 GMANAQGYLPAHDAAGFDKRLDAIAATVCPNDPRTPDQRRADALGALGRY
TH_0334|M.thermoresistible__bu GMVDVSARLTFEAGFAFXTRLDQIAATVCRDDPRTADQRRADAMAAMSEG
Mb0528|M.bovis_AF2122/97 GVCQIGGSLLAVDAHALDARLSALAGTVCEHDPRSREQRRADALGALAGG
Rv0515|M.tuberculosis_H37Rv GVCQIGGSLLAVDAHALDARLSALAGTVCEHDPRSREQRRADALGALAGG
MMAR_2226|M.marinum_M GLAALTGSVLATAGRAFDRRLDELANTVCAADPRTREQRRADAVGALVAG
MUL_1813|M.ulcerans_Agy99 GLAALAGSVLATAGRAFDRRLDELANTVCAADPRTREQRRADAVGALVAG
MAV_3457|M.avium_104 GMAWVEGNVLGPDGHALDRRLDELASGVCAGDPRSRAQRRADALGALAAG
MAB_4752|M.abscessus_ATCC_1997 PVAEVWGTLQAVHAVALDKRLDLLAGTVCPADPRSKTQRRADAVGALTQG
: . : . .: **. :* ** ***: : **** .*:
Mflv_3596|M.gilvum_PYR-GCK EATLACQCGGDDCPAVALRESAAKVVIHILAEQATVEGRSDDPGYLSGFG
Mvan_3778|M.vanbaalenii_PYR-1 ESTLTCECGAEDCPAAVLRESAAQVVIHILAEQATVDGDGDKAGYLPGFG
MSMEG_5026|M.smegmatis_MC2_155 RDTLDCQCGREDCTAVAERDAVNNAMIHVLAEQSTLDG-GNEPGYLPGFG
TH_0334|M.thermoresistible__bu QNRLVCGCGSEDCPADPADTAATRLVINVIAEQATVEGRSDNPGYLPGYG
Mb0528|M.bovis_AF2122/97 ADRLGCGCGRADCAAGKRPAA-PPVVIHLIAEAATINGTGSAPASQMNAD
Rv0515|M.tuberculosis_H37Rv ADRLGCGCGRADCAAGKRPAA-PPVVIHLIAEAATINGTGSAPASQMNAD
MMAR_2226|M.marinum_M SDRLACGCTSADCTAAARSAP-SNVVIHVVADQSTVDGTGHTPAVLLGAE
MUL_1813|M.ulcerans_Agy99 SDRLACGCTSADCTAAARSAP-SKVVIHVVADQSTVDGTGHTPAVLLGAE
MAV_3457|M.avium_104 AGRLACGCGSPDCPSAAAPAPRSTVVIHVVAEQATVAGRGATPAVVAGLD
MAB_4752|M.abscessus_ATCC_1997 LNRMRCACGHPDCSG--RDTADVPVVVNVVINQSTLAGSDDCPAHVPGFG
: * * **.. . ::::: : :*: * . .. .
Mflv_3596|M.gilvum_PYR-GCK -VLPAEEVRAAARTAKLVPVSQP-GTEPETGYKPSAKLRDYLRWRDLTCR
Mvan_3778|M.vanbaalenii_PYR-1 -VLPAEEVRAAAKTAKLKPVRLP-GAEPEKGYRPSAGLKDFLQWRDLTCR
MSMEG_5026|M.smegmatis_MC2_155 -MLPAHMVREVAKTATTKPVTIP-KDKAQSGYRPNAELTEFIRWRDLTCR
TH_0334|M.thermoresistible__bu -AVPASILRAKAATATLRPVALP-QPCAEAGYRPSAALTRFIRCRDLTCR
Mb0528|M.bovis_AF2122/97 GLITAELVAELAKTATLVPLVHPGDAPPEPGYAPSKALADFVRCRDLTCR
Rv0515|M.tuberculosis_H37Rv GLITAELVAELAKTATLVPLVHPGDAPPEPGYAPSKALADFVRCRDLTCR
MMAR_2226|M.marinum_M GLIPASLIAELAKVATLRPLMRP-SGRPESGYAPSAGLAEFVRCRDLTCR
MUL_1813|M.ulcerans_Agy99 GLIPASLIAELAKVATLRPLMRP-SGRPESGYAPSAGLAEFVRCRDLTCR
MAV_3457|M.avium_104 GLIPAQVIAELAASARLVPVAVP-EGGPEPGYTPSARLADFIRCRDLTCR
MAB_4752|M.abscessus_ATCC_1997 -----VLAAESARAAVAGTPTRNLTDSRSTGYRPSAKLAAFVRSRDQLCR
* * . . ** *. * ::: ** **
Mflv_3596|M.gilvum_PYR-GCK FPGCDAPVEGCDVDHTTPWPFG-VTHASGTKHYCRTHHLIKTFYGGPSGW
Mvan_3778|M.vanbaalenii_PYR-1 FPGCDAPVERCDVDHTTRWPFG-VTHASGLKHYCRTHHVIKTFLTGVYGW
MSMEG_5026|M.smegmatis_MC2_155 FPGCDAPAMAADIDHTRPYPQG-PTHPSNTKLYCRTHHLIKTFYTGPNGW
TH_0334|M.thermoresistible__bu FPGCDAPAAVCQIDHTIPYPAG-PTHPSNLKLLCVFHCRQAELR-----F
Mb0528|M.bovis_AF2122/97 WPGCDEPATNCDLDHTIPYAAGGPTHASNLKCYCRTHHLVKTFWG----W
Rv0515|M.tuberculosis_H37Rv WPGCDEPATNCDLDHTIPYAAGGPTHASNLKCYCRTHHLVKTFWG----W
MMAR_2226|M.marinum_M APGCDQPAVCCDLDHTVAYGDGGHTHASNLKCLCRKHHLLKTFWD----W
MUL_1813|M.ulcerans_Agy99 ARGCDQPAVCCDLDHTVAYGDGGHTHASNLKCLCRKHHLLKTFWG----W
MAV_3457|M.avium_104 APGCDRPAVDCDVDHTIPYAQGGPTHPSNLKCLCRGHHLLKTFWG----W
MAB_4752|M.abscessus_ATCC_1997 FPGCEAVADRADIDHTVPWATGGPTTGANLKALCRKHHLLKTFGQ----W
**: . .::*** : * * :. * * * : :
Mflv_3596|M.gilvum_PYR-GCK RDAQSPDGTVVVIAPTGHVYSTEAHGAGLFPKLAEPTAPLPPPTSTQEP-
Mvan_3778|M.vanbaalenii_PYR-1 RDEQRRDGTVVLTAPTGHVYTTEPLGGLLFPTLATPTAPLPDVEVPEDD-
MSMEG_5026|M.smegmatis_MC2_155 TDRQLPDGTIEFTAPTGHIYTTEPQGAALFPVLGTPTGELNLPPQQDEPH
TH_0334|M.thermoresistible__bu THDQHKHQSSCLPA-----YFQRPHG-----------------PATRRP-
Mb0528|M.bovis_AF2122/97 RDQQLPDGTLILTSPSGHTYVSTPGSALLFPSLCHFSGGIPAPEADPP--
Rv0515|M.tuberculosis_H37Rv RDQQLPDGTLILTSPSGHTYVSTPGSALLFPSLCHFSGGIPAPEADPP--
MMAR_2226|M.marinum_M RDLQLPDGTVIWLLPDGHTYVTTPGSALLFPNLCVPTGGLPPIVGTAG--
MUL_1813|M.ulcerans_Agy99 RDLQLPDGTVIWLLPDGHTYVTTPGSALLFPNLCVPTGELPPIVGTAGKP
MAV_3457|M.avium_104 RDRQLPDGTVIWTLPDGDTYVTTPGSALLFPTLCTPTGAVSPAKPDTE--
MAB_4752|M.abscessus_ATCC_1997 TELQEPDGTVIWKSPTGHRYATTPVSWFLFPALT----------------
. * . : * . .
Mflv_3596|M.gilvum_PYR-GCK ----------------SDKSAMMPRRKRTREQDRRARIERERRQ-----R
Mvan_3778|M.vanbaalenii_PYR-1 ----------------PDKAAMMPRR-RTREQERRARIARERRQ-----R
MSMEG_5026|M.smegmatis_MC2_155 ----------------PNRGVMMPKRRQTREQDRADRINAERRE-----R
TH_0334|M.thermoresistible__bu -----------------------PSARGLREAVPRQGVDPRR--------
Mb0528|M.bovis_AF2122/97 ------------YDHCDQRTAMMPKRRRTRAQDRAYRIATERRQ------
Rv0515|M.tuberculosis_H37Rv ------------YDHCDQRTAMMPKRRRTRAQDRAYRIATERRQ------
MMAR_2226|M.marinum_M -------------SPRAGRAARMPTRARTRAQNRANRIDTERR-------
MUL_1813|M.ulcerans_Agy99 PRWPSGEDADPCPNPRTKPGESHRHRAPMQSQGTGSRRRRPRRPVRHPGA
MAV_3457|M.avium_104 -------------HRCGERTAMMPLRRHTRAHNRAHRITTERN-------
MAB_4752|M.abscessus_ATCC_1997 -------------------------RHHTRQQARDRRRRTERN-------
: *
Mflv_3596|M.gilvum_PYR-GCK IELDAEEERQRQAWLAET--------------YEPPPF------------
Mvan_3778|M.vanbaalenii_PYR-1 IEINAERERQHQAWLAAT--------------YEPPPF------------
MSMEG_5026|M.smegmatis_MC2_155 AELNAEQQRQRQAWLADN--------------YEPPPF------------
TH_0334|M.thermoresistible__bu --VSGQ--------------------------------------------
Mb0528|M.bovis_AF2122/97 -NHAARQRAQVLTQTAAATDTH---GPPPDHNDDPPPF------------
Rv0515|M.tuberculosis_H37Rv -NHAARQRAQVLTQTAAATDTH---GPPPDHNDDPPPF------------
MMAR_2226|M.marinum_M --CNRRALEAVGGVHADRYDTP---EPTIGPDEPPPF-------------
MUL_1813|M.ulcerans_Agy99 GNRSRRAAALLAATSLGTCQIPRRIAPRPGPSRSSRGCTDSGTRMGESSM
MAV_3457|M.avium_104 --HNRRTRLTTHPATPG----P---APPPDPDDEPPPF------------
MAB_4752|M.abscessus_ATCC_1997 --LNREQRLQREAALAAL------------AAKDPPPF------------
.
Mflv_3596|M.gilvum_PYR-GCK ----------
Mvan_3778|M.vanbaalenii_PYR-1 ----------
MSMEG_5026|M.smegmatis_MC2_155 ----------
TH_0334|M.thermoresistible__bu ----------
Mb0528|M.bovis_AF2122/97 ----------
Rv0515|M.tuberculosis_H37Rv ----------
MMAR_2226|M.marinum_M ----------
MUL_1813|M.ulcerans_Agy99 SARPRACVAG
MAV_3457|M.avium_104 ----------
MAB_4752|M.abscessus_ATCC_1997 ----------